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Items: 1 to 50 of 1148

1.

Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models.

Murakami T, Hiroshima Y, Miyake K, Kiyuna T, Endo I, Zhao M, Hoffman RM.

Cells. 2019 Jun 16;8(6). pii: E599. doi: 10.3390/cells8060599. Review.

2.

The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model.

Miyake K, Higuchi T, Oshiro H, Zhang Z, Sugisawa N, Park JH, Razmjooei S, Katsuya Y, Barangi M, Li Y, Nelson SD, Murakami T, Homma Y, Hiroshima Y, Matsuyama R, Bouvet M, Chawla SP, Singh SR, Endo I, Hoffman RM.

Biomed Pharmacother. 2019 Jun 11;117:109093. doi: 10.1016/j.biopha.2019.109093. [Epub ahead of print]

3.

Perceived Acceptability of a Facility-Based HIV Self-Test Intervention in Outpatient Waiting Spaces Among Adult Outpatients in Malawi: A Formative Study.

Shaba F, Offorjebe OA, Phiri K, Lungu E, Kalande P, Nyirenda M, Hoffman RM, Gupta S, Dovel K.

J Acquir Immune Defic Syndr. 2019 Jul 1;81(3):e92-e94. doi: 10.1097/QAI.0000000000002055. No abstract available.

PMID:
31194705
4.

RE: "Intraoperative Near-infrared Imaging Can Identify Neoplasms and Aid in Real-time Margin Assessment During Pancreatic Resection".

Bouvet M, Lwin TM, Hoffman RM.

Ann Surg. 2019 Jul;270(1):21-22. doi: 10.1097/SLA.0000000000003360. No abstract available.

PMID:
31188174
5.

Markers of Spontaneuous Preterm Delivery in Women living with HIV: Relationship with Protease Inhibitors and Vitamin D.

Weinberg A, Huo Y, Kacanek D, Patel K, Watts DH, Wara D, Hoffman RM, Klawitter J, Christians U; for IMPAACT P1025 Team.

J Acquir Immune Defic Syndr. 2019 May 28. doi: 10.1097/QAI.0000000000002111. [Epub ahead of print]

PMID:
31180997
6.

Traditional Chinese Medicine (TCM) Astragalus Membranaceus and Curcuma Wenyujin Promote Vascular Normalization in Tumor-derived Endothelial Cells of Human Hepatocellular Carcinoma.

Zang W, Bian H, Huang X, Yin G, Zhang C, Han LI, Hao P, Ding S, Sun YU, Yang Z, Hoffman RM, Tang D.

Anticancer Res. 2019 Jun;39(6):2739-2747. doi: 10.21873/anticanres.13400.

PMID:
31177109
7.

Knockdown of Histone Methyltransferase WHSC1 Induces Apoptosis and Inhibits Cell Proliferation and Tumorigenesis in Salivary Adenoid Cystic Carcinoma.

Liu C, Jiang YH, Zhao ZL, Wu HW, Zhang L, Yang Z, Hoffman RM, Zheng JW.

Anticancer Res. 2019 Jun;39(6):2729-2737. doi: 10.21873/anticanres.13399.

PMID:
31177108
8.

Targeting neddylation inhibits intravascular survival and extravasation of cancer cells to prevent lung-cancer metastasis.

Jiang Y, Liang Y, Li L, Zhou L, Cheng W, Yang X, Yang X, Qi H, Yu J, Jeong LS, Hoffman RM, Zheng P, Jia L.

Cell Biol Toxicol. 2019 Jun;35(3):233-245. doi: 10.1007/s10565-019-09472-w. Epub 2019 May 28.

PMID:
31140025
9.

Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model.

Oshiro H, Tome Y, Kiyuna T, Miyake K, Kawaguchi K, Higuchi T, Miyake M, Zang Z, Razmjooei S, Barangi M, Wangsiricharoen S, Nelson SD, Li Y, Bouvet M, Singh SR, Kanaya F, Hoffman RM.

Tissue Cell. 2019 Jun;58:17-23. doi: 10.1016/j.tice.2019.04.002. Epub 2019 Apr 3.

PMID:
31133242
10.

Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model.

Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Singh SR, Tsuchiya H, Hoffman RM.

Tissue Cell. 2019 Jun;58:107-111. doi: 10.1016/j.tice.2019.04.010. Epub 2019 May 3.

PMID:
31133237
11.

Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models.

Hollandsworth HM, Lwin TM, Amirfakhri S, Filemoni F, Batra SK, Hoffman RM, Dhawan P, Bouvet M.

J Surg Res. 2019 May 8;242:145-150. doi: 10.1016/j.jss.2019.04.048. [Epub ahead of print]

PMID:
31077946
12.

Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review.

Kawaguchi K, Han Q, Li S, Tan Y, Igarashi K, Murakami T, Unno M, Hoffman RM.

Cells. 2019 May 2;8(5). pii: E410. doi: 10.3390/cells8050410. Review.

13.

Tenofovir concentrations in hair strongly predict virologic suppression in breastfeeding women.

Murnane PM, Bacchetti P, Currier JS, Brummel S, Okochi H, Phung N, Louie A, Kuncze K, Hoffman RM, Nematadzira T, Soko DK, Owor M, Saidi F, Flynn PM, Fowler MG, Gandhi M.

AIDS. 2019 Apr 22. doi: 10.1097/QAD.0000000000002237. [Epub ahead of print]

PMID:
31021852
14.

Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model.

Higuchi T, Miyake K, Oshiro H, Sugisawa N, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.

Biochem Biophys Res Commun. 2019 May 28;513(2):326-331. doi: 10.1016/j.bbrc.2019.03.191. Epub 2019 Apr 5.

PMID:
30955860
15.

Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model.

Miyake K, Murata T, Murakami T, Zhao M, Kiyuna T, Kawaguchi K, Igarashi K, Miyake M, Lwin TM, Hozumi C, Komatsu S, Kikuchi T, Bouvet M, Shimoya K, Singh SR, Endo I, Hoffman RM.

Arch Gynecol Obstet. 2019 Jun;299(6):1683-1690. doi: 10.1007/s00404-019-05147-3. Epub 2019 Apr 5.

PMID:
30953192
16.

P-Glycoprotein Overexpression Is Associated With Cisplatin Resistance in Human Osteosarcoma.

He C, Sun Z, Hoffman RM, Yang Z, Jiang Y, Wang L, Hao Y.

Anticancer Res. 2019 Apr;39(4):1711-1718. doi: 10.21873/anticanres.13277.

PMID:
30952710
17.

Chemo-resistant Gastric Cancer Associated Gene Expression Signature: Bioinformatics Analysis Based on Gene Expression Omnibus.

Liu JB, Jian T, Yue C, Chen D, Chen W, Bao TT, Liu HX, Cao Y, Li WB, Yang Z, Hoffman RM, Yu C.

Anticancer Res. 2019 Apr;39(4):1689-1698. doi: 10.21873/anticanres.13274.

PMID:
30952707
18.

Post-imaging pulmonary nodule mathematical prediction models: are they clinically relevant?

Uthoff J, Koehn N, Larson J, Dilger SKN, Hammond E, Schwartz A, Mullan B, Sanchez R, Hoffman RM, Sieren JC; COPDGene Investigators.

Eur Radiol. 2019 Apr 1. doi: 10.1007/s00330-019-06168-x. [Epub ahead of print]

PMID:
30937590
19.

Decision-Making in a Time of Uncertainty: Dolutegravir for Reproductive-Age Women.

Hoffman RM, Mofenson LM.

Ann Intern Med. 2019 Apr 2. doi: 10.7326/M19-0641. [Epub ahead of print] No abstract available.

PMID:
30934065
20.

The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model.

Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.

Cancer Chemother Pharmacol. 2019 Jun;83(6):1075-1082. doi: 10.1007/s00280-019-03824-3. Epub 2019 Mar 30.

PMID:
30929053
21.

Role of the tumor microenvironment in pancreatic cancer.

Murakami T, Hiroshima Y, Matsuyama R, Homma Y, Hoffman RM, Endo I.

Ann Gastroenterol Surg. 2019 Jan 4;3(2):130-137. doi: 10.1002/ags3.12225. eCollection 2019 Mar. Review.

22.

Maternal health outcomes among HIV-infected breastfeeding women with high CD4 counts: results of a treatment strategy trial.

Hoffman RM, Angelidou KN, Brummel SS, Saidi F, Violari A, Dula D, Mave V, Fairlie L, Theron G, Kamateeka M, Chipato T, Chi BH, Stranix-Chibanda L, Nematadzira T, Moodley D, Bhattacharya D, Gupta A, Coletti A, McIntyre JA, Klingman KL, Chakhtoura N, Shapiro DE, Fowler MG, Currier JS; IMPAACT PROMISE 1077BF/FF team.

HIV Clin Trials. 2018 Dec;19(6):209-224. doi: 10.1080/15284336.2018.1537327.

PMID:
30890061
23.

Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model.

Higuchi T, Miyake K, Sugisawa N, Oshiro H, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.

Cancer Lett. 2019 Jun 1;451:122-127. doi: 10.1016/j.canlet.2019.03.003. Epub 2019 Mar 10.

PMID:
30867142
24.

╬▓-Catenin Expression Correlates With Prognosis in Hepatocellular Carcinoma Patients Treated With Transcatheter Arterial Chemoembolization.

Xu X, Gao D, Yuan X, Liu LI, Zhang X, Liang X, Chen S, Ai M, Chen BO, Shi D, Yang Z, Hoffman RM, Xu J.

Anticancer Res. 2019 Mar;39(3):1129-1134. doi: 10.21873/anticanres.13221.

PMID:
30842141
25.

Provider perspectives on barriers to reproductive health services for HIV-infected clients in Central Malawi.

Caplan MR, Phiri K, Parent J, Phoya A, Schooley A, Hoffman RM.

Clin Obstet Gynecol Reprod Med. 2018 Feb;4(1). doi: 10.15761/COGRM.1000208. Epub 2018 Feb 12.

26.

Surgical and histological boundary of the hepatic hilar plate system: basic study relevant to surgery for hilar cholangiocarcinoma regarding the "true" proximal ductal margin.

Kikuchi Y, Matuyama R, Hiroshima Y, Murakami T, Bouvet M, Morioka D, Hoffman RM, Endo I.

J Hepatobiliary Pancreat Sci. 2019 May;26(5):159-168. doi: 10.1002/jhbp.617. Epub 2019 Mar 31.

PMID:
30825363
27.

Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice.

Higuchi T, Oshiro H, Zhang Z, Miyake K, Sugisawa N, Katsuya Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Zhao M, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.

Transl Oncol. 2019 Apr;12(4):640-645. doi: 10.1016/j.tranon.2019.01.007. Epub 2019 Feb 23.

28.

A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma.

Zhang Z, Hu K, Kiyuna T, Miyake K, Kawaguchi K, Igarashi K, Nelson SD, Li Y, Singh SR, Hoffman RM.

Pharmacol Res. 2019 Apr;142:169-175. doi: 10.1016/j.phrs.2019.02.021. Epub 2019 Feb 23.

PMID:
30807865
29.

Regorafenib regressed a doxorubicin-resistant Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model.

Miyake K, Kiyuna T, Kawaguchi K, Higuchi T, Oshiro H, Zhang Z, Wangsiricharoen S, Razmjooei S, Li Y, Nelson SD, Murakami T, Hiroshima Y, Matsuyama R, Bouvet M, Chawla SP, Singh SR, Endo I, Hoffman RM.

Cancer Chemother Pharmacol. 2019 May;83(5):809-815. doi: 10.1007/s00280-019-03782-w. Epub 2019 Feb 13.

PMID:
30758647
30.

Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth?

Hoffman RM, Han Q, Kawaguchi K, Li S, Tan Y.

Methods Mol Biol. 2019;1866:311-322. doi: 10.1007/978-1-4939-8796-2_24.

PMID:
30725426
31.

Recombinant Methioninase as a DNA Demethylation Agent.

Hoffman RM, Machover D.

Methods Mol Biol. 2019;1866:279-284. doi: 10.1007/978-1-4939-8796-2_22.

PMID:
30725424
32.

Is the Hoffman Effect for Methionine Overuse Analogous to the Warburg Effect for Glucose Overuse in Cancer?

Hoffman RM.

Methods Mol Biol. 2019;1866:273-278. doi: 10.1007/978-1-4939-8796-2_21.

PMID:
30725423
33.

L-[Methyl-11C] Methionine-Positron-Emission Tomography (MET-PET).

Hoffman RM.

Methods Mol Biol. 2019;1866:267-271. doi: 10.1007/978-1-4939-8796-2_20.

PMID:
30725422
34.

Methionine Restriction and Life-Span Extension.

Hoffman RM.

Methods Mol Biol. 2019;1866:263-266. doi: 10.1007/978-1-4939-8796-2_19.

PMID:
30725421
35.

Pilot Phase I Clinical Trial of Methioninase on High-Stage Cancer Patients: Rapid Depletion of Circulating Methionine.

Hoffman RM, Tan Y, Li S, Han Q, Zavala J Sr, Zavala J Jr.

Methods Mol Biol. 2019;1866:231-242. doi: 10.1007/978-1-4939-8796-2_17.

PMID:
30725419
36.

Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates.

Hoffman RM, Yang Z, Tan Y, Han Q, Li S, Yagi S.

Methods Mol Biol. 2019;1866:211-229. doi: 10.1007/978-1-4939-8796-2_16.

PMID:
30725418
37.

Methioninase Gene Therapy.

Hoffman RM, Miki K, Al-Refaie W, Xu M, Tan Y.

Methods Mol Biol. 2019;1866:173-197. doi: 10.1007/978-1-4939-8796-2_14.

PMID:
30725416
38.

Total Methionine Restriction Treatment of Cancer.

Hoffman RM, Kokkinakis DM, Frenkel EP.

Methods Mol Biol. 2019;1866:163-171. doi: 10.1007/978-1-4939-8796-2_13.

PMID:
30725415
39.

High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer.

Hoffman RM, Murakami T, Kawaguchi K, Igarashi K, Tan Y, Li S, Han Q.

Methods Mol Biol. 2019;1866:149-161. doi: 10.1007/978-1-4939-8796-2_12.

PMID:
30725414
40.

Methioninase Cell-Cycle Trap Cancer Chemotherapy.

Hoffman RM, Yano S, Igarashi K.

Methods Mol Biol. 2019;1866:133-148. doi: 10.1007/978-1-4939-8796-2_11.

PMID:
30725413
41.

Development of Recombinant Methioninase for Cancer Treatment.

Hoffman RM, Tan Y, Li S, Han Q, Yagi S, Takakura T, Takimoto A, Inagaki K, Kudou D.

Methods Mol Biol. 2019;1866:107-131. doi: 10.1007/978-1-4939-8796-2_10.

PMID:
30725412
42.

Clinical Studies of Methionine-Restricted Diets for Cancer Patients.

Hoffman RM.

Methods Mol Biol. 2019;1866:95-105. doi: 10.1007/978-1-4939-8796-2_9.

PMID:
30725411
43.

Dietary Methionine Restriction-Based Cancer Chemotherapy in Rodents.

Hoffman RM, Stern PH.

Methods Mol Biol. 2019;1866:83-94. doi: 10.1007/978-1-4939-8796-2_8.

PMID:
30725410
44.

Efficacy of Methionine-Restricted Diets on Cancers In Vivo.

Hoffman RM, Hoshiya Y, Guo W.

Methods Mol Biol. 2019;1866:75-81. doi: 10.1007/978-1-4939-8796-2_7.

PMID:
30725409
45.

Tumor-Specific S/G2-Phase Cell Cycle Arrest of Cancer Cells by Methionine Restriction.

Hoffman RM, Yano S.

Methods Mol Biol. 2019;1866:49-60. doi: 10.1007/978-1-4939-8796-2_5.

PMID:
30725407
46.

Linkage of Methionine Dependence and Other Features of Malignancy.

Hoffman RM, Erbe RW.

Methods Mol Biol. 2019;1866:27-36. doi: 10.1007/978-1-4939-8796-2_3.

PMID:
30725405
47.

Altered Methionine Metabolism in Cancer Cells.

Hoffman RM, Stern PH, Coalson DW, Douglas Wallace C, Erbe RW.

Methods Mol Biol. 2019;1866:13-26. doi: 10.1007/978-1-4939-8796-2_2.

PMID:
30725404
48.

Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model.

Miyake K, Kiyuna T, Li S, Han Q, Tan Y, Zhao M, Oshiro H, Kawaguchi K, Higuchi T, Zhang Z, Razmjooei S, Barangi M, Wangsiricharoen S, Murakami T, Singh AS, Li Y, Nelson SD, Eilber FC, Bouvet M, Hiroshima Y, Chishima T, Matsuyama R, Singh SR, Endo I, Hoffman RM.

Chemotherapy. 2018;63(5):278-283. doi: 10.1159/000495574. Epub 2019 Jan 23.

PMID:
30673664
49.

Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model.

Miyake K, Kiyuna T, Miyake M, Kawaguchi K, Zhang Z, Wangsiricharoen S, Razmjooei S, Oshiro H, Higuchi T, Li Y, Nelson SD, Murakami T, Hiroshima Y, Kumamoto T, Matsuyama R, Bouvet M, Singh SR, Chawla SP, Endo I, Hoffman RM.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):1041-1046. doi: 10.1016/j.bbrc.2019.01.046. Epub 2019 Jan 16.

PMID:
30660363
50.

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model.

Lwin TM, Miyake K, Murakami T, DeLong JC, Amirfakhri S, Filemoni F, Yoon SN, Yazaki PJ, Shivley JE, Datnow B, Clary BM, Hoffman RM, Bouvet M.

Oncotarget. 2018 Dec 18;9(99):37333-37342. doi: 10.18632/oncotarget.26484. eCollection 2018 Dec 18.

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