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Midwest Nursing Research Society News.

Hoffman AJ, Larson JL.

West J Nurs Res. 2018 Aug;40(8):1265-1270. doi: 10.1177/0193945918784686. No abstract available.


Enhancing oral bioavailability of cyclic RGD hexa-peptides by the Lipophilic Prodrug Charge Masking approach: Redirection of peptide intestinal permeability from paracellular to transcellular pathway.

Schumacher-Klinger A, Fanous J, Merzbach S, Weinmueller M, Reichart F, Räder AFB, Gitlin-Domaglaska A, Gilon C, Kessler H, Hoffman A.

Mol Pharm. 2018 Jul 5. doi: 10.1021/acs.molpharmaceut.8b00466. [Epub ahead of print]


Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity.

Michaelides M, Miller ML, Egervari G, Primeaux SD, Gomez JL, Ellis RJ, Landry JA, Szutorisz H, Hoffman AF, Lupica CR, Loos RJF, Thanos PK, Bray GA, Neumaier JF, Zachariou V, Wang GJ, Volkow ND, Hurd YL.

Mol Psychiatry. 2018 Jun 28. doi: 10.1038/s41380-018-0120-7. [Epub ahead of print]


20 years of researching stroke through audit.

Rudd AG, Hoffman A, Paley L, Bray B.

Clin Rehabil. 2018 Jun 1:269215518784645. doi: 10.1177/0269215518784645. [Epub ahead of print]


Development of a Novel Backbone Cyclic Peptide Inhibitor of the Innate Immune TLR/IL1R Signaling Protein MyD88.

Dishon S, Schumacher A, Fanous J, Talhami A, Kassis I, Karussis D, Gilon C, Hoffman A, Nussbaum G.

Sci Rep. 2018 Jun 21;8(1):9476. doi: 10.1038/s41598-018-27773-8.


The economic burden of stroke care in England, Wales and Northern Ireland: Using a national stroke register to estimate and report patient-level health economic outcomes in stroke.

Xu XM, Vestesson E, Paley L, Desikan A, Wonderling D, Hoffman A, Wolfe CD, Rudd AG, Bray BD.

Eur Stroke J. 2018 Mar;3(1):82-91. doi: 10.1177/2396987317746516. Epub 2017 Nov 30.


Early stress priming and the effects on fitness-related traits following an adult stress exposure.

Hoffman AJ, Finger JW Jr, Wada H.

J Exp Zool A Ecol Integr Physiol. 2018 Jun 12. doi: 10.1002/jez.2190. [Epub ahead of print]


Mitochondrial peptides modulate mitochondrial function during cellular senescence.

Kim SJ, Mehta HH, Wan J, Kuehnemann C, Chen J, Hu JF, Hoffman AR, Cohen P.

Aging (Albany NY). 2018 Jun 10;10(6):1239-1256. doi: 10.18632/aging.101463.


Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels.

Hoffman A, Taleski G, Qian H, Wasek B, Arning E, Bottiglieri T, Sontag JM, Sontag E.

J Alzheimers Dis. 2018;64(1):223-237. doi: 10.3233/JAD-180032.


Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressors.

Wang H, Guo R, Du Z, Bai L, Li L, Cui J, Li W, Hoffman AR, Hu JF.

Mol Ther Nucleic Acids. 2018 Jun 1;11:23-33. doi: 10.1016/j.omtn.2018.01.002. Epub 2018 Jan 8.


The Ethics of Medicaid's Work Requirements and Other Personal Responsibility Policies.

Schmidt H, Hoffman AK.

JAMA. 2018 Jun 12;319(22):2265-2266. doi: 10.1001/jama.2018.3384. No abstract available.


Value-Added Activities in Medical Education: A Multi-Site Survey of First- and Second-Year Medical Students' Perceptions and Factors Influencing Their Potential Engagement.

Leep Hunderfund AN, Starr SR, Dyrbye LN, Gonzalo JD, George P, Miller BM, Morgan HK, Hoffman A, Baxley EG, Allen BL, Fancher TL, Mandrekar J, Skochelak SE, Reed DA.

Acad Med. 2018 May 22. doi: 10.1097/ACM.0000000000002299. [Epub ahead of print]


Management of Incidental Pituitary Findings on CT, MRI, and 18F-Fluorodeoxyglucose PET: A White Paper of the ACR Incidental Findings Committee.

Hoang JK, Hoffman AR, González RG, Wintermark M, Glenn BJ, Pandharipande PV, Berland LL, Seidenwurm DJ.

J Am Coll Radiol. 2018 Jul;15(7):966-972. doi: 10.1016/j.jacr.2018.03.037. Epub 2018 May 4.


Associations Between Lean Mass, Muscle Strength and Power, and Skeletal Size, Density and Strength in Older Men.

Chalhoub D, Boudreau R, Greenspan S, Newman AB, Zmuda J, Frank-Wilson AW, Nagaraj N, Hoffman AR, Lane NE, Stefanick ML, Barrett-Connor E, Dam T, Cawthon PM, Orwoll ES, Cauley JA; Osteoporotic Fractures in Men (MrOS) Study Research Group.

J Bone Miner Res. 2018 Apr 27. doi: 10.1002/jbmr.3458. [Epub ahead of print]


Effects of the Tempering and High-Pressure Torsion Temperatures on Microstructure of Ferritic/Martensitic Steel Grade 91.

Ganeev A, Nikitina M, Sitdikov V, Islamgaliev R, Hoffman A, Wen H.

Materials (Basel). 2018 Apr 19;11(4). pii: E627. doi: 10.3390/ma11040627.


Correction: Development and validation of the SIMPLE endoscopic classification of diminutive and small colorectal polyps.

Iacucci M, Trovato C, Daperno M, Akinola O, Greenwald D, Gross SA, Hoffman A, Lee J, Lethebe BC, Lowerison M, Nayor J, Neumann H, Rath T, Sanduleanu S, Sharma P, Kiesslich R, Ghosh S, Saltzman JR; and the SIMPLE classification investigator team.

Endoscopy. 2018 Apr 17. doi: 10.1055/a-0607-2062. [Epub ahead of print] No abstract available.


Low colostrum yield in Jersey cattle and potential risk factors.

Gavin K, Neibergs H, Hoffman A, Kiser JN, Cornmesser MA, Haredasht SA, Martínez-López B, Wenz JR, Moore DA.

J Dairy Sci. 2018 Jul;101(7):6388-6398. doi: 10.3168/jds.2017-14308. Epub 2018 Mar 28.


Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units.

Clarke DJ, Burton LJ, Tyson SF, Rodgers H, Drummond A, Palmer R, Hoffman A, Prescott M, Tyrrell P, Brkic L, Grenfell K, Forster A.

Clin Rehabil. 2018 Mar 1:269215518765329. doi: 10.1177/0269215518765329. [Epub ahead of print]


Weight loss in men in late life and bone strength and microarchitecture: a prospective study.

Ensrud KE, Vo TN, Burghardt AJ, Schousboe JT, Cauley JA, Taylor BC, Hoffman AR, Orwoll ES, Lane NE, Langsetmo L; Osteoporotic Fractures in Men (MrOS) Research Group.

Osteoporos Int. 2018 Jul;29(7):1549-1558. doi: 10.1007/s00198-018-4489-6. Epub 2018 Mar 23.


Development and validation of the SIMPLE endoscopic classification of diminutive and small colorectal polyps.

Iacucci M, Trovato C, Daperno M, Akinola O, Greenwald D, Gross SA, Hoffman A, Lee J, Lethebe BC, Lowerison M, Nayor J, Neumann H, Rath T, Sanduleanu S, Sharma P, Kiesslich R, Ghosh S, Saltzman JR; and the SIMPLE classification investigator team.

Endoscopy. 2018 Mar 23. doi: 10.1055/s-0044-100791. [Epub ahead of print]


Socioeconomic disparities in first stroke incidence, quality of care, and survival: a nationwide registry-based cohort study of 44 million adults in England.

Bray BD, Paley L, Hoffman A, James M, Gompertz P, Wolfe CDA, Hemingway H, Rudd AG; SSNAP Collaboration.

Lancet Public Health. 2018 Apr;3(4):e185-e193. doi: 10.1016/S2468-2667(18)30030-6. Epub 2018 Mar 15.


Primary Care Preparation for Children with Medical Complexity for Emergency Encounters in the Community.

Hoffman A, Larson IA.

Pediatr Ann. 2018 Mar 1;47(3):e102-e105. doi: 10.3928/19382359-20180221-02. Review.


The Effect of Piperine Pro-Nano Lipospheres on Direct Intestinal Phase II Metabolism: The Raloxifene Paradigm of Enhanced Oral Bioavailability.

Izgelov D, Cherniakov I, Aldouby Bier G, Domb AJ, Hoffman A.

Mol Pharm. 2018 Apr 2;15(4):1548-1555. doi: 10.1021/acs.molpharmaceut.7b01090. Epub 2018 Mar 19.


Growth Hormone Research Society perspective on biomarkers of GH action in children and adults.

Johannsson G, Bidlingmaier M, Biller BMK, Boguszewski M, Casanueva FF, Chanson P, Clayton PE, Choong CS, Clemmons D, Dattani M, Frystyk J, Ho K, Hoffman AR, Horikawa R, Juul A, Kopchick JJ, Luo X, Neggers S, Netchine I, Olsson DS, Radovick S, Rosenfeld R, Ross RJ, Schilbach K, Solberg P, Strasburger C, Trainer P, Yuen KCJ, Wickstrom K, Jorgensen JOL; Growth Hormone Research Society.

Endocr Connect. 2018 Mar;7(3):R126-R134. doi: 10.1530/EC-18-0047. Epub 2018 Feb 26. Review.


Children with medical complexities: Addressing the gaps in respite care during transition from paediatrics to adult health care in Ontario.

Porepa M, Hoffman A, Fellin M, Kublick L.

Paediatr Child Health. 2017 Oct;22(7):369-371. doi: 10.1093/pch/pxx142. Epub 2017 Oct 6.


Engineering optical emission in sub-diffraction hyperbolic metamaterial resonators.

Feng K, Sivco DL, Hoffman AJ.

Opt Express. 2018 Feb 19;26(4):4382-4391. doi: 10.1364/OE.26.004382.


Codominant grasses differ in gene expression under experimental climate extremes in native tallgrass prairie.

Hoffman AM, Avolio ML, Knapp AK, Smith MD.

PeerJ. 2018 Feb 14;6:e4394. doi: 10.7717/peerj.4394. eCollection 2018.


Explanation and elaboration of the Standards for UNiversal reporting of patient Decision Aid Evaluations (SUNDAE) guidelines: examples of reporting SUNDAE items from patient decision aid evaluation literature.

Hoffman AS, Sepucha KR, Abhyankar P, Sheridan S, Bekker H, LeBlanc A, Levin C, Ropka M, Shaffer V, Stacey D, Stalmeier P, Vo H, Wills C, Thomson R.

BMJ Qual Saf. 2018 May;27(5):389-412. doi: 10.1136/bmjqs-2017-006985. Epub 2018 Feb 21.


Pathways: patient-centred decision counselling for women at risk of cancer-related infertility: a protocol for a comparative effectiveness cluster randomised trial.

Woodard TL, Hoffman AS, Crocker LC, Holman DA, Hoffman DB, Ma J, Bassett RL Jr, Leal VB, Volk RJ.

BMJ Open. 2018 Feb 21;8(2):e019994. doi: 10.1136/bmjopen-2017-019994.


Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema.

Borel F, Sun H, Zieger M, Cox A, Cardozo B, Li W, Oliveira G, Davis A, Gruntman A, Flotte TR, Brodsky MH, Hoffman AM, Elmallah MK, Mueller C.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2788-2793. doi: 10.1073/pnas.1713689115. Epub 2018 Feb 16.


Elucidating the Vibrational Fingerprint of the Flexible Metal-Organic Framework MIL-53(Al) Using a Combined Experimental/Computational Approach.

Hoffman AEJ, Vanduyfhuys L, Nevjestić I, Wieme J, Rogge SMJ, Depauw H, Van Der Voort P, Vrielinck H, Van Speybroeck V.

J Phys Chem C Nanomater Interfaces. 2018 Feb 8;122(5):2734-2746. doi: 10.1021/acs.jpcc.7b11031. Epub 2018 Jan 8.


Serum Sodium and Cognition in Older Community-Dwelling Men.

Nowak KL, Yaffe K, Orwoll ES, Ix JH, You Z, Barrett-Connor E, Hoffman AR, Chonchol M.

Clin J Am Soc Nephrol. 2018 Mar 7;13(3):366-374. doi: 10.2215/CJN.07400717. Epub 2018 Feb 8.


Oncoprotein AEG-1 is an endoplasmic reticulum RNA-binding protein whose interactome is enriched in organelle resident protein-encoding mRNAs.

Hsu JC, Reid DW, Hoffman AM, Sarkar D, Nicchitta CV.

RNA. 2018 May;24(5):688-703. doi: 10.1261/rna.063313.117. Epub 2018 Feb 7.


Hospital readmission rates and risk factors for readmission following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal surface malignancies.

Dreznik Y, Hoffman A, Hamburger T, Ben-Yaacov A, Dux Y, Jacoby H, Berger Y, Nissan A, Gutman M.

Surgeon. 2018 Feb 8. pii: S1479-666X(18)30013-1. doi: 10.1016/j.surge.2018.01.001. [Epub ahead of print]


G-EYE advanced colonoscopy for improved polyp detection rates - a randomized tandem pilot study with different endoscopists.

Rey JW, Dümcke S, Haschemi J, Tresch A, Borger D, Kirchner AC, Teubner D, Kiesslich R, Hoffman A.

Z Gastroenterol. 2018 Feb 9. doi: 10.1055/s-0043-124089. [Epub ahead of print]


The Manchester Triage System (MTS): a score for emergency management of patients with acute gastrointestinal bleeding.

Nguyen-Tat M, Cornelius C, Hoffman A, Tresch A, Krey J, Kiesslich R, Galle PR, Rey JW.

Z Gastroenterol. 2018 Feb 9. doi: 10.1055/s-0043-124194. [Epub ahead of print]


Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor.

Yano H, Cai NS, Xu M, Verma RK, Rea W, Hoffman AF, Shi L, Javitch JA, Bonci A, Ferré S.

Nat Commun. 2018 Feb 5;9(1):486. doi: 10.1038/s41467-017-02606-w.


Toxicokinetics of the neonicotinoid insecticide imidacloprid in rainbow trout (Oncorhynchus mykiss).

Frew JA, Brown JT, Fitzsimmons PN, Hoffman AD, Sadilek M, Grue CE, Nichols JW.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Feb;205:34-42. doi: 10.1016/j.cbpc.2018.01.002. Epub 2018 Feb 3.


Society of Biomolecular Imaging and Informatics High-Content Screening/High-Content Analysis Emerging Technologies in Biological Models, When and Why?

Hoffman AF, Nolan J, Gebhard DF, Nickischer D, Omta W, Cooper S, Presnell S, Wardwell-Swanson J, Fennell M.

Assay Drug Dev Technol. 2018 Jan;16(1):1-6. doi: 10.1089/adt.2017.29070.afh. No abstract available.


Fortuitous benefits of living kidney donation: Diagnosis of serious medical conditions during the living donor evaluation.

Hoffman A, Tendulkar K, Merani S, Maskin A, Langnas A.

Clin Transplant. 2018 Mar;32(3):e13204. doi: 10.1111/ctr.13204. Epub 2018 Feb 6.


Twelve Lessons Learned for Effective Research Partnerships Between Patients, Caregivers, Clinicians, Academic Researchers, and Other Stakeholders.

Witteman HO, Chipenda Dansokho S, Colquhoun H, Fagerlin A, Giguere AMC, Glouberman S, Haslett L, Hoffman A, Ivers NM, Légaré F, Légaré J, Levin CA, Lopez K, Montori VM, Renaud JS, Sparling K, Stacey D, Volk RJ.

J Gen Intern Med. 2018 Apr;33(4):558-562. doi: 10.1007/s11606-017-4269-6. Epub 2018 Jan 4.


Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.

Eriksson AL, Perry JRB, Coviello AD, Delgado GE, Ferrucci L, Hoffman AR, Huhtaniemi IT, Ikram MA, Karlsson MK, Kleber ME, Laughlin GA, Liu Y, Lorentzon M, Lunetta KL, Mellström D, Murabito JM, Murray A, Nethander M, Nielson CM, Prokopenko I, Pye SR, Raffel LJ, Rivadeneira F, Srikanth P, Stolk L, Teumer A, Travison TG, Uitterlinden AG, Vaidya D, Vanderschueren D, Zmuda JM, März W, Orwoll ES, Ouyang P, Vandenput L, Wu FCW, de Jong FH, Bhasin S, Kiel DP, Ohlsson C.

J Clin Endocrinol Metab. 2018 Mar 1;103(3):991-1004. doi: 10.1210/jc.2017-02060.


Dysregulation of valvular interstitial cell let-7c, miR-17, miR-20a, and miR-30d in naturally occurring canine myxomatous mitral valve disease.

Yang VK, Tai AK, Huh TP, Meola DM, Juhr CM, Robinson NA, Hoffman AM.

PLoS One. 2018 Jan 9;13(1):e0188617. doi: 10.1371/journal.pone.0188617. eCollection 2018.


Implications of Stoma Formation as Part of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.

Jacoby H, Berger Y, Barda L, Sharif N, Zager Y, Lebedyev A, Gutman M, Hoffman A.

World J Surg. 2018 Jul;42(7):2036-2042. doi: 10.1007/s00268-017-4450-4.


PTL401, a New Formulation Based on Pro-Nano Dispersion Technology, Improves Oral Cannabinoids Bioavailability in Healthy Volunteers.

Atsmon J, Cherniakov I, Izgelov D, Hoffman A, Domb AJ, Deutsch L, Deutsch F, Heffetz D, Sacks H.

J Pharm Sci. 2018 May;107(5):1423-1429. doi: 10.1016/j.xphs.2017.12.020. Epub 2017 Dec 26.


Standards for UNiversal reporting of patient Decision Aid Evaluation studies: the development of SUNDAE Checklist.

Sepucha KR, Abhyankar P, Hoffman AS, Bekker HL, LeBlanc A, Levin CA, Ropka M, Shaffer VA, Sheridan SL, Stacey D, Stalmeier P, Vo H, Wills CE, Thomson R.

BMJ Qual Saf. 2018 May;27(5):380-388. doi: 10.1136/bmjqs-2017-006986. Epub 2017 Dec 21.


Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework.

Glusman G, Rose PW, Prlić A, Dougherty J, Duarte JM, Hoffman AS, Barton GJ, Bendixen E, Bergquist T, Bock C, Brunk E, Buljan M, Burley SK, Cai B, Carter H, Gao J, Godzik A, Heuer M, Hicks M, Hrabe T, Karchin R, Leman JK, Lane L, Masica DL, Mooney SD, Moult J, Omenn GS, Pearl F, Pejaver V, Reynolds SM, Rokem A, Schwede T, Song S, Tilgner H, Valasatava Y, Zhang Y, Deutsch EW.

Genome Med. 2017 Dec 18;9(1):113. doi: 10.1186/s13073-017-0509-y.


Two-Dimensional Fluorescence Difference Spectroscopy of ZnO and Mg Composites in the Detection of Physiological Protein and RNA Interactions.

Hoffman A, Wu X, Wang J, Brodeur A, Thomas R, Thakkar R, Hadi H, Glaspell GP, Duszynski M, Wanekaya A, DeLong RK.

Materials (Basel). 2017 Dec 15;10(12). pii: E1430. doi: 10.3390/ma10121430.


Oestrogen receptor β ligand acts on CD11c+ cells to mediate protection in experimental autoimmune encephalomyelitis.

Kim RY, Mangu D, Hoffman AS, Kavosh R, Jung E, Itoh N, Voskuhl R.

Brain. 2018 Jan 1;141(1):132-147. doi: 10.1093/brain/awx315.


A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness.

Lai J, Moya L, An J, Hoffman A, Srinivasan S, Panchadsaram J, Walpole C, Perry-Keene JL, Chambers S; Australian Prostate Cancer BioResource, Lehman ML, Nelson CC, Clements JA, Batra J.

Sci Rep. 2017 Dec 4;7(1):16862. doi: 10.1038/s41598-017-16700-y.

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