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Items: 36


Collateral Damage: What Effect Does Anti-CD4 and Anti-CD8α Antibody-Mediated Depletion Have on Leukocyte Populations?

Jung SR, Suprunenko T, Ashhurst TM, King NJC, Hofer MJ.

J Immunol. 2018 Oct 1;201(7):2176-2186. doi: 10.4049/jimmunol.1800339. Epub 2018 Aug 24.


Microglia have a more extensive and divergent response to interferon-α compared with astrocytes.

Li W, Viengkhou B, Denyer G, West PK, Campbell IL, Hofer MJ.

Glia. 2018 Oct;66(10):2058-2078. doi: 10.1002/glia.23460. Epub 2018 Jul 27.


Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7.

Vachharajani N, Joeris T, Luu M, Hartmann S, Pautz S, Jenike E, Pantazis G, Prinz I, Hofer MJ, Steinhoff U, Visekruna A.

Oncotarget. 2017 Jan 10;8(31):50447-50459. doi: 10.18632/oncotarget.14579. eCollection 2017 Aug 1.


IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection.

Huber M, Suprunenko T, Ashhurst T, Marbach F, Raifer H, Wolff S, Strecker T, Viengkhou B, Jung SR, Obermann HL, Bauer S, Xu HC, Lang PA, Tom A, Lang KS, King NJC, Campbell IL, Hofer MJ.

J Virol. 2017 Oct 27;91(22). pii: e01219-17. doi: 10.1128/JVI.01219-17. Print 2017 Nov 15.


Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9.

Li W, Hofer MJ, Songkhunawej P, Jung SR, Hancock D, Denyer G, Campbell IL.

J Biol Chem. 2017 Apr 7;292(14):5845-5859. doi: 10.1074/jbc.M116.756510. Epub 2017 Feb 17.


The emerging role of interferon regulatory factor 9 in the antiviral host response and beyond.

Suprunenko T, Hofer MJ.

Cytokine Growth Factor Rev. 2016 Jun;29:35-43. doi: 10.1016/j.cytogfr.2016.03.002. Epub 2016 Mar 4. Review.


Deterministic Assembly of Complex Bacterial Communities in Guts of Germ-Free Cockroaches.

Mikaelyan A, Thompson CL, Hofer MJ, Brune A.

Appl Environ Microbiol. 2015 Dec 11;82(4):1256-63. doi: 10.1128/AEM.03700-15. Print 2016 Feb 15.


Immunoinflammatory diseases of the central nervous system - the tale of two cytokines.

Hofer MJ, Campbell IL.

Br J Pharmacol. 2016 Feb;173(4):716-28. doi: 10.1111/bph.13175. Epub 2015 Jun 12. Review.


Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10.

Almolda B, de Labra C, Barrera I, Gruart A, Delgado-Garcia JM, Villacampa N, Vilella A, Hofer MJ, Hidalgo J, Campbell IL, González B, Castellano B.

Brain Behav Immun. 2015 Mar;45:80-97. doi: 10.1016/j.bbi.2014.10.015. Epub 2014 Oct 31.


Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.

Visekruna A, Linnerz T, Martinic V, Vachharajani N, Hartmann S, Harb H, Joeris T, Pfefferle PI, Hofer MJ, Steinhoff U.

Mucosal Immunol. 2015 Mar;8(2):307-15. doi: 10.1038/mi.2014.68. Epub 2014 Aug 6.


IRF7-dependent type I interferon production induces lethal immune-mediated disease in STAT1 knockout mice infected with lymphocytic choriomeningitis virus.

Li W, Hofer MJ, Jung SR, Lim SL, Campbell IL.

J Virol. 2014 Jul;88(13):7578-88. doi: 10.1128/JVI.03117-13. Epub 2014 Apr 23.


The bacteriostatic protein lipocalin 2 is induced in the central nervous system of mice with west Nile virus encephalitis.

Noçon AL, Ip JP, Terry R, Lim SL, Getts DR, Müller M, Hofer MJ, King NJ, Campbell IL.

J Virol. 2014 Jan;88(1):679-89. doi: 10.1128/JVI.02094-13. Epub 2013 Oct 30.


Distinct microscopic features of perineural invasion in adenoid cystic carcinoma of the head and neck.

Teymoortash A, Zieger L, Hoch S, Pagenstecher A, Hofer MJ.

Histopathology. 2014 Jun;64(7):1037-9. doi: 10.1111/his.12210. Epub 2013 Aug 19. No abstract available.


IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock.

Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, Weber M, Kalinke U, Hofer MJ, Hatesuer B, Schughart K, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Weber F, Hornef MW, Autenrieth IB, Bohn E.

J Immunol. 2013 Oct 1;191(7):3913-21. doi: 10.4049/jimmunol.1203305. Epub 2013 Sep 6.


Type I interferon in neurological disease-the devil from within.

Hofer MJ, Campbell IL.

Cytokine Growth Factor Rev. 2013 Jun;24(3):257-67. doi: 10.1016/j.cytogfr.2013.03.006. Epub 2013 Mar 30. Review.


Interferon regulatory factor 7 (IRF7) is required for the optimal initial control but not subsequent clearance of lymphocytic choriomeningitis virus infection in mice.

Li W, Hofer MJ, Noçon AL, Manders P, Campbell IL.

Virology. 2013 May 10;439(2):152-62. doi: 10.1016/j.virol.2013.02.015. Epub 2013 Mar 12.


CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia.

Zimmermann J, Krauthausen M, Hofer MJ, Heneka MT, Campbell IL, Müller M.

PLoS One. 2013;8(2):e57307. doi: 10.1371/journal.pone.0057307. Epub 2013 Feb 27.


Multiple system atrophy of the cerebellar type (MSA-C) with concomitant beta-amyloid and tau pathology.

Bujan B, Hofer MJ, Oertel WH, Pagenstecher A, Bürk K.

Clin Neuropathol. 2013 Jul-Aug;32(4):286-90. doi: 10.5414/NP300572.


A 62-year-old female with an intranasal mass extending into the lamina cribrosa.

Hofer MJ, Rohlfs J, Teymoortash A, Pagenstecher A.

Brain Pathol. 2013 Jan;23(1):105-8. doi: 10.1111/bpa.12010.


Painful muscle fibrosis following synthol injections in a bodybuilder: a case report.

Ghandourah S, Hofer MJ, Kießling A, El-Zayat B, Schofer MD.

J Med Case Rep. 2012 Aug 20;6:248.


Genomic profiling to assess the clonal relationship between histologically distinct intracranial tumours.

Hofer MJ, Riehmer V, Kuhnt D, Braun V, Nimsky C, Weber RG, Sommer C, Pagenstecher A.

Neuropathol Appl Neurobiol. 2012 Aug;38(5):500-4. doi: 10.1111/j.1365-2990.2012.01280.x. No abstract available.


Mice deficient in STAT1 but not STAT2 or IRF9 develop a lethal CD4+ T-cell-mediated disease following infection with lymphocytic choriomeningitis virus.

Hofer MJ, Li W, Manders P, Terry R, Lim SL, King NJ, Campbell IL.

J Virol. 2012 Jun;86(12):6932-46. doi: 10.1128/JVI.07147-11. Epub 2012 Apr 11.


Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration.

Ip JP, Noçon AL, Hofer MJ, Lim SL, Müller M, Campbell IL.

J Neuroinflammation. 2011 Sep 26;8:124. doi: 10.1186/1742-2094-8-124.


The cell-specific induction of CXC chemokine ligand 9 mediated by IFN-gamma in microglia of the central nervous system is determined by the myeloid transcription factor PU.1.

Ellis SL, Gysbers V, Manders PM, Li W, Hofer MJ, Müller M, Campbell IL.

J Immunol. 2010 Aug 1;185(3):1864-77. doi: 10.4049/jimmunol.1000900. Epub 2010 Jun 28.


Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity--a tale of conflict and conundrum.

Müller M, Carter S, Hofer MJ, Campbell IL.

Neuropathol Appl Neurobiol. 2010 Aug;36(5):368-87. doi: 10.1111/j.1365-2990.2010.01089.x. Epub 2010 May 6. Review.


Community dynamics in the mouse gut microbiota: a possible role for IRF9-regulated genes in community homeostasis.

Thompson CL, Hofer MJ, Campbell IL, Holmes AJ.

PLoS One. 2010 Apr 23;5(4):e10335. doi: 10.1371/journal.pone.0010335.


The type I interferon-alpha mediates a more severe neurological disease in the absence of the canonical signaling molecule interferon regulatory factor 9.

Hofer MJ, Li W, Lim SL, Campbell IL.

J Neurosci. 2010 Jan 20;30(3):1149-57. doi: 10.1523/JNEUROSCI.3711-09.2010.


Transgenic models for cytokine-induced neurological disease.

Campbell IL, Hofer MJ, Pagenstecher A.

Biochim Biophys Acta. 2010 Oct;1802(10):903-17. doi: 10.1016/j.bbadis.2009.10.004. Epub 2009 Oct 14. Review.


Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitis.

Quintana A, Müller M, Frausto RF, Ramos R, Getts DR, Sanz E, Hofer MJ, Krauthausen M, King NJ, Hidalgo J, Campbell IL.

J Immunol. 2009 Aug 1;183(3):2079-88. doi: 10.4049/jimmunol.0900242. Epub 2009 Jul 13.


Intracerebral interleukin 12 induces glioma rejection in the brain predominantly by CD8+ T cells and independently of interferon-gamma.

Vetter M, Hofer MJ, Roth E, Pircher HP, Pagenstecher A.

J Neuropathol Exp Neurol. 2009 May;68(5):525-34. doi: 10.1097/NEN.0b013e3181a2afa0.


Unaltered neurological disease and mortality in CXCR3-deficient mice infected intracranially with lymphocytic choriomeningitis virus-Armstrong.

Hofer MJ, Carter SL, Müller M, Campbell IL.

Viral Immunol. 2008 Dec;21(4):425-33. doi: 10.1089/vim.2008.0057.


Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain.

Sanz E, Hofer MJ, Unzeta M, Campbell IL.

Glia. 2008 Jan 15;56(2):190-9.


CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system.

Müller M, Carter SL, Hofer MJ, Manders P, Getts DR, Getts MT, Dreykluft A, Lu B, Gerard C, King NJ, Campbell IL.

J Immunol. 2007 Sep 1;179(5):2774-86.


Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses.

Wacher C, Müller M, Hofer MJ, Getts DR, Zabaras R, Ousman SS, Terenzi F, Sen GC, King NJ, Campbell IL.

J Virol. 2007 Jan;81(2):860-71. Epub 2006 Nov 1.


Absence of Borna disease virus in the CNS of epilepsy patients.

Hofer MJ, Schindler AR, Ehrensperger F, Staeheli P, Pagenstecher A.

J Clin Virol. 2006 May;36(1):84-5. Epub 2006 Feb 21. No abstract available.


Molecular genotyping of the murine H-2K MHC class I allele.

Hofer MJ, Finger C, Pagenstecher A.

J Immunol Methods. 2005 Jul;302(1-2):168-71.


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