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Items: 1 to 50 of 88

1.

Redox Cofactor Rotates during Its Stepwise Decarboxylation: Molecular Mechanism of Conversion of Coproheme to Heme b.

Milazzo L, Gabler T, Pühringer D, Jandova Z, Maresch D, Michlits H, Pfanzagl V, Djinović-Carugo K, Oostenbrink C, Furtmüller PG, Obinger C, Smulevich G, Hofbauer S.

ACS Catal. 2019 Aug 2;9(8):6766-6782. doi: 10.1021/acscatal.9b00963. Epub 2019 Jun 18.

2.

Redox thermodynamics of B-class dye-decolorizing peroxidases.

Pfanzagl V, Bellei M, Hofbauer S, Laurent CVFP, Furtmüller PG, Oostenbrink C, Battistuzzi G, Obinger C.

J Inorg Biochem. 2019 Oct;199:110761. doi: 10.1016/j.jinorgbio.2019.110761. Epub 2019 Jul 11.

PMID:
31325671
3.

Outcome of Photoselective Vaporization of the Prostate with the GreenLight-XPS 180 Watt System Compared to Transurethral Resection of the Prostate.

Reimann M, Fishman N, Lichy I, Wiemer L, Hofbauer S, Almedom Z, Buckendahl J, Steiner U, Schlomm T, Friedersdorff F, Cash H.

J Clin Med. 2019 Jul 10;8(7). pii: E1004. doi: 10.3390/jcm8071004.

4.

Monomeric and homotrimeric solution structures of truncated human peroxidasin 1 variants.

Paumann-Page M, Tscheliessnig R, Sevcnikar B, Katz RS, Schwartz I, Hofbauer S, Pfanzagl V, Furtmüller PG, Obinger C.

Biochim Biophys Acta Proteins Proteom. 2019 Jul 8:140249. doi: 10.1016/j.bbapap.2019.07.002. [Epub ahead of print]

5.

Urinary expression of genes involved in DNA methylation and histone modification for diagnosis of bladder cancer in patients with asymptomatic microscopic haematuria.

Lucca I, Hofbauer SL, Haitel A, Susani M, Shariat SF, Klatte T, De Martino M.

Oncol Lett. 2019 Jul;18(1):57-62. doi: 10.3892/ol.2019.10330. Epub 2019 May 7.

6.

The hydrogen bonding network of coproheme in coproheme decarboxylase from Listeria monocytogenes: Effect on structure and catalysis.

Milazzo L, Gabler T, Pfanzagl V, Michlits H, Furtmüller PG, Obinger C, Hofbauer S, Smulevich G.

J Inorg Biochem. 2019 Jun;195:61-70. doi: 10.1016/j.jinorgbio.2019.03.009. Epub 2019 Mar 21.

7.

Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions.

Olivé M, Engvall M, Ravenscroft G, Cabrera-Serrano M, Jiao H, Bortolotti CA, Pignataro M, Lambrughi M, Jiang H, Forrest ARR, Benseny-Cases N, Hofbauer S, Obinger C, Battistuzzi G, Bellei M, Borsari M, Di Rocco G, Viola HM, Hool LC, Cladera J, Lagerstedt-Robinson K, Xiang F, Wredenberg A, Miralles F, Baiges JJ, Malfatti E, Romero NB, Streichenberger N, Vial C, Claeys KG, Straathof CSM, Goris A, Freyer C, Lammens M, Bassez G, Kere J, Clemente P, Sejersen T, Udd B, Vidal N, Ferrer I, Edström L, Wedell A, Laing NG.

Nat Commun. 2019 Mar 27;10(1):1396. doi: 10.1038/s41467-019-09111-2.

8.

Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells.

Lee SC, Shestov AA, Guo L, Zhang Q, Roman JC, Liu X, Wang HY, Pickup S, Nath K, Lu P, Hofbauer S, Mesaros C, Wang YL, Nelson DS, Schuster SJ, Blair IA, Glickson JD, Wasik MA.

Mol Cancer Res. 2019 Jun;17(6):1365-1377. doi: 10.1158/1541-7786.MCR-18-0256. Epub 2019 Mar 12.

PMID:
30862686
9.

Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry.

Kuskovsky R, Buj R, Xu P, Hofbauer S, Doan MT, Jiang H, Bostwick A, Mesaros C, Aird KM, Snyder NW.

Anal Biochem. 2019 Mar 1;568:65-72. doi: 10.1016/j.ab.2018.12.023. Epub 2018 Dec 31.

PMID:
30605633
10.

A urinary microRNA (miR) signature for diagnosis of bladder cancer.

Hofbauer SL, de Martino M, Lucca I, Haitel A, Susani M, Shariat SF, Klatte T.

Urol Oncol. 2018 Dec;36(12):531.e1-531.e8. doi: 10.1016/j.urolonc.2018.09.006. Epub 2018 Oct 12.

PMID:
30322728
11.

Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage.

Pfanzagl V, Nys K, Bellei M, Michlits H, Mlynek G, Battistuzzi G, Djinovic-Carugo K, Van Doorslaer S, Furtmüller PG, Hofbauer S, Obinger C.

J Biol Chem. 2018 Sep 21;293(38):14823-14838. doi: 10.1074/jbc.RA118.004773. Epub 2018 Aug 2.

12.

Validation of Prostate Imaging Reporting and Data System Version 2 for the Detection of Prostate Cancer.

Hofbauer SL, Maxeiner A, Kittner B, Heckmann R, Reimann M, Wiemer L, Asbach P, Haas M, Penzkofer T, Stephan C, Friedersdorff F, Fuller F, Miller K, Cash H.

J Urol. 2018 Oct;200(4):767-773. doi: 10.1016/j.juro.2018.05.003. Epub 2018 May 5.

PMID:
29733838
13.

Primary magnetic resonance imaging/ultrasonography fusion-guided biopsy of the prostate.

Maxeiner A, Kittner B, Blobel C, Wiemer L, Hofbauer SL, Fischer T, Asbach P, Haas M, Penzkofer T, Fuller F, Miller K, Cash H.

BJU Int. 2018 Aug;122(2):211-218. doi: 10.1111/bju.14212. Epub 2018 Apr 17.

14.

Insights into the Active Site of Coproheme Decarboxylase from Listeria monocytogenes.

Milazzo L, Hofbauer S, Howes BD, Gabler T, Furtmüller PG, Obinger C, Smulevich G.

Biochemistry. 2018 Apr 3;57(13):2044-2057. doi: 10.1021/acs.biochem.8b00186. Epub 2018 Mar 22.

15.

Acceptance of Adjuvant and Neoadjuvant Chemotherapy in Muscle-Invasive Bladder Cancer in Germany: A Survey of Current Practice.

Dogan S, Hennig M, Frank T, Struck JP, Cebulla A, Salem J, Borgmann H, Klatte T, Merseburger AS, Kramer M, Hofbauer SL.

Urol Int. 2018;101(1):25-30. doi: 10.1159/000487405. Epub 2018 Mar 6.

PMID:
29510388
16.

Posttranslational modification of heme in peroxidases - Impact on structure and catalysis.

Nicolussi A, Auer M, Sevcnikar B, Paumann-Page M, Pfanzagl V, Zámocký M, Hofbauer S, Furtmüller PG, Obinger C.

Arch Biochem Biophys. 2018 Apr 2;643:14-23. doi: 10.1016/j.abb.2018.02.008. Epub 2018 Feb 17. Review.

17.

Coproheme decarboxylases - Phylogenetic prediction versus biochemical experiments.

Pfanzagl V, Holcik L, Maresch D, Gorgone G, Michlits H, Furtmüller PG, Hofbauer S.

Arch Biochem Biophys. 2018 Feb 15;640:27-36. doi: 10.1016/j.abb.2018.01.005. Epub 2018 Jan 10.

18.

Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies.

Schaffner I, Mlynek G, Flego N, Pühringer D, Libiseller-Egger J, Coates L, Hofbauer S, Bellei M, Furtmüller PG, Battistuzzi G, Smulevich G, Djinović-Carugo K, Obinger C.

ACS Catal. 2017 Nov 3;7(11):7962-7976. doi: 10.1021/acscatal.7b01749. Epub 2017 Oct 13.

19.

Posttranslational Modification of Heme b in a Bacterial Peroxidase: The Role of Heme to Protein Ester Bonds in Ligand Binding and Catalysis.

Nicolussi A, Auer M, Weissensteiner J, Schütz G, Katz S, Maresch D, Hofbauer S, Bellei M, Battistuzzi G, Furtmüller PG, Obinger C.

Biochemistry. 2017 Aug 29;56(34):4525-4538. doi: 10.1021/acs.biochem.7b00632. Epub 2017 Aug 16.

PMID:
28762722
20.

Serum Adiponectin Predicts Cancer-specific Survival of Patients with Renal Cell Carcinoma.

de Martino M, Leitner CV, Hofbauer SL, Lucca I, Haitel A, Shariat SF, Klatte T.

Eur Urol Focus. 2016 Jun;2(2):197-203. doi: 10.1016/j.euf.2015.06.012. Epub 2015 Jul 15.

PMID:
28723535
21.

Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation.

Grishkovskaya I, Paumann-Page M, Tscheliessnig R, Stampler J, Hofbauer S, Soudi M, Sevcnikar B, Oostenbrink C, Furtmüller PG, Djinović-Carugo K, Nauseef WM, Obinger C.

J Biol Chem. 2017 May 19;292(20):8244-8261. doi: 10.1074/jbc.M117.775031. Epub 2017 Mar 27.

22.

Pre-steady-state Kinetics Reveal the Substrate Specificity and Mechanism of Halide Oxidation of Truncated Human Peroxidasin 1.

Paumann-Page M, Katz RS, Bellei M, Schwartz I, Edenhofer E, Sevcnikar B, Soudi M, Hofbauer S, Battistuzzi G, Furtmüller PG, Obinger C.

J Biol Chem. 2017 Mar 17;292(11):4583-4592. doi: 10.1074/jbc.M117.775213. Epub 2017 Jan 31.

23.

Hydrogen peroxide-mediated conversion of coproheme to heme b by HemQ-lessons from the first crystal structure and kinetic studies.

Hofbauer S, Mlynek G, Milazzo L, Pühringer D, Maresch D, Schaffner I, Furtmüller PG, Smulevich G, Djinović-Carugo K, Obinger C.

FEBS J. 2016 Dec;283(23):4386-4401. doi: 10.1111/febs.13930. Epub 2016 Nov 14.

24.

[Modern networks : Topics in the working group "Bladder cancer research" of the GeSRU Academics].

Hofbauer S, Kalogirou C, Roghmann F, Seitz AK, Vallo S, Wezel F, Worst T, Nawroth R.

Urologe A. 2017 Feb;56(2):202-207. doi: 10.1007/s00120-016-0217-z. Review. German.

PMID:
27604705
25.

Chemistry and Molecular Dynamics Simulations of Heme b-HemQ and Coproheme-HemQ.

Hofbauer S, Dalla Sega M, Scheiblbrandner S, Jandova Z, Schaffner I, Mlynek G, Djinović-Carugo K, Battistuzzi G, Furtmüller PG, Oostenbrink C, Obinger C.

Biochemistry. 2016 Sep 27;55(38):5398-412. doi: 10.1021/acs.biochem.6b00701. Epub 2016 Sep 15.

26.

Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes.

Ruivo EF, Gonçalves LM, Carvalho LA, Guedes RC, Hofbauer S, Brito JA, Archer M, Moreira R, Lucas SD.

ChemMedChem. 2016 Sep 20;11(18):2037-42. doi: 10.1002/cmdc.201600258. Epub 2016 Jul 28.

PMID:
27465595
27.

Development of a Preoperative Nomogram Incorporating Biomarkers of Systemic Inflammatory Response to Predict Nonorgan-confined Urothelial Carcinoma of the Bladder at Radical Cystectomy.

Lucca I, Hofbauer SL, Leitner CV, de Martino M, Özsoy M, Susani M, Shariat SF, Klatte T.

Urology. 2016 Sep;95:132-8. doi: 10.1016/j.urology.2016.06.007. Epub 2016 Jun 15.

PMID:
27316373
28.

From chlorite dismutase towards HemQ - the role of the proximal H-bonding network in haeme binding.

Hofbauer S, Howes BD, Flego N, Pirker KF, Schaffner I, Mlynek G, Djinović-Carugo K, Furtmüller PG, Smulevich G, Obinger C.

Biosci Rep. 2016 Feb 8;36(2). pii: e00312. doi: 10.1042/BSR20150330.

29.

ILK Induction in Lymphoid Organs by a TNFα-NF-κB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.

Krenn PW, Hofbauer SW, Pucher S, Hutterer E, Hinterseer E, Denk U, Asslaber D, Ganghammer S, Sternberg C, Neureiter D, Aberger F, Wickström SA, Egle A, Greil R, Hartmann TN.

Cancer Res. 2016 Apr 15;76(8):2186-96. doi: 10.1158/0008-5472.CAN-15-3379. Epub 2016 Feb 2.

30.

Dynamic Prognostication Using Conditional Recurrence and Progression Estimates for Patients with Nonmuscle Invasive Bladder Cancer.

Leitner CV, Ederer IA, de Martino M, Hofbauer SL, Lucca I, Mbeutcha A, Mathieu R, Haitel A, Susani M, Shariat SF, Klatte T.

J Urol. 2016 Jul;196(1):46-51. doi: 10.1016/j.juro.2016.01.102. Epub 2016 Feb 2.

PMID:
26835832
31.

The Moreau Strain of Bacillus Calmette-Guerin (BCG) for High-Risk Non-Muscle Invasive Bladder Cancer: An Alternative during Worldwide BCG Shortage?

Hofbauer SL, Shariat SF, Chade DC, Sarkis AS, Ribeiro-Filho LA, Nahas WC, Klatte T.

Urol Int. 2016;96(1):46-50. doi: 10.1159/000440701. Epub 2015 Nov 11.

PMID:
26555711
32.

Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking.

Hofbauer S, Brito JA, Mulchande J, Nogly P, Pessanha M, Moreira R, Archer M.

Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1346-51. doi: 10.1107/S2053230X15017045. Epub 2015 Sep 23.

33.

Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology.

de Martino M, Taus C, Lucca I, Hofbauer SL, Haitel A, Shariat SF, Klatte T.

Mol Carcinog. 2016 Oct;55(10):1458-66. doi: 10.1002/mc.22388. Epub 2015 Aug 21.

PMID:
26294352
34.

Eukaryotic Catalase-Peroxidase: The Role of the Trp-Tyr-Met Adduct in Protein Stability, Substrate Accessibility, and Catalysis of Hydrogen Peroxide Dismutation.

Gasselhuber B, Carpena X, Graf MM, Pirker KF, Nicolussi A, Sündermann A, Hofbauer S, Zamocky M, Furtmüller PG, Jakopitsch C, Oostenbrink C, Fita I, Obinger C.

Biochemistry. 2015 Sep 8;54(35):5425-38. doi: 10.1021/acs.biochem.5b00831. Epub 2015 Aug 25.

PMID:
26290940
35.

Monocyte subset distribution in patients with stable atherosclerosis and elevated levels of lipoprotein(a).

Krychtiuk KA, Kastl SP, Hofbauer SL, Wonnerth A, Goliasch G, Ozsvar-Kozma M, Katsaros KM, Maurer G, Huber K, Dostal E, Binder CJ, Pfaffenberger S, Oravec S, Wojta J, Speidl WS.

J Clin Lipidol. 2015 Jul-Aug;9(4):533-41. doi: 10.1016/j.jacl.2015.04.005. Epub 2015 Apr 25.

36.

The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.

Hofbauer SW, Krenn PW, Piñόn Hofbauer J, Pucher S, Asslaber D, Egle A, Hartmann TN, Greil R.

Br J Haematol. 2016 Mar;172(5):815-9. doi: 10.1111/bjh.13542. Epub 2015 Jul 6. No abstract available.

37.

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis.

Park J, Schlederer M, Schreiber M, Ice R, Merkel O, Bilban M, Hofbauer S, Kim S, Addison J, Zou J, Ji C, Bunting ST, Wang Z, Shoham M, Huang G, Bago-Horvath Z, Gibson LF, Rojanasakul Y, Remick S, Ivanov A, Pugacheva E, Bunting KD, Moriggl R, Kenner L, Tse W.

Oncotarget. 2015 Aug 21;6(24):20697-710.

38.

Comparison of the prognostic value of pretreatment measurements of systemic inflammatory response in patients undergoing curative resection of clear cell renal cell carcinoma.

Lucca I, de Martino M, Hofbauer SL, Zamani N, Shariat SF, Klatte T.

World J Urol. 2015 Dec;33(12):2045-52. doi: 10.1007/s00345-015-1559-7. Epub 2015 Apr 17.

PMID:
25894368
39.

Histopathology and prognosis of de novo bladder tumors following solid organ transplantation.

Ederer IA, Lucca I, Hofbauer SL, Haidinger M, Haitel A, Susani M, Shariat SF, Klatte T.

World J Urol. 2015 Dec;33(12):2087-93. doi: 10.1007/s00345-015-1554-z. Epub 2015 Apr 10.

PMID:
25860378
40.

Association of small dense LDL serum levels and circulating monocyte subsets in stable coronary artery disease.

Krychtiuk KA, Kastl SP, Pfaffenberger S, Lenz M, Hofbauer SL, Wonnerth A, Koller L, Katsaros KM, Pongratz T, Goliasch G, Niessner A, Gaspar L, Huber K, Maurer G, Dostal E, Wojta J, Oravec S, Speidl WS.

PLoS One. 2015 Apr 7;10(4):e0123367. doi: 10.1371/journal.pone.0123367. eCollection 2015.

41.

Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM.

Chromikova V, Mader A, Hofbauer S, Göbl C, Madl T, Gach JS, Bauernfried S, Furtmüller PG, Forthal DN, Mach L, Obinger C, Kunert R.

Biochim Biophys Acta. 2015 Oct;1854(10 Pt A):1536-44. doi: 10.1016/j.bbapap.2015.02.018. Epub 2015 Mar 5.

42.

Mechanism of chlorite degradation to chloride and dioxygen by the enzyme chlorite dismutase.

Schaffner I, Hofbauer S, Krutzler M, Pirker KF, Furtmüller PG, Obinger C.

Arch Biochem Biophys. 2015 May 15;574:18-26. doi: 10.1016/j.abb.2015.02.031. Epub 2015 Mar 4. Review.

43.

Dimeric chlorite dismutase from the nitrogen-fixing cyanobacterium Cyanothece sp. PCC7425.

Schaffner I, Hofbauer S, Krutzler M, Pirker KF, Bellei M, Stadlmayr G, Mlynek G, Djinovic-Carugo K, Battistuzzi G, Furtmüller PG, Daims H, Obinger C.

Mol Microbiol. 2015 Jun;96(5):1053-68. doi: 10.1111/mmi.12989. Epub 2015 Apr 6.

44.

Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia.

Kern D, Regl G, Hofbauer SW, Altenhofer P, Achatz G, Dlugosz A, Schnidar H, Greil R, Hartmann TN, Aberger F.

Oncogene. 2015 Oct 16;34(42):5341-51. doi: 10.1038/onc.2014.450. Epub 2015 Feb 2.

45.

Structure and heme-binding properties of HemQ (chlorite dismutase-like protein) from Listeria monocytogenes.

Hofbauer S, Hagmüller A, Schaffner I, Mlynek G, Krutzler M, Stadlmayr G, Pirker KF, Obinger C, Daims H, Djinović-Carugo K, Furtmüller PG.

Arch Biochem Biophys. 2015 May 15;574:36-48. doi: 10.1016/j.abb.2015.01.010. Epub 2015 Jan 17.

46.

Independent evolution of four heme peroxidase superfamilies.

Zámocký M, Hofbauer S, Schaffner I, Gasselhuber B, Nicolussi A, Soudi M, Pirker KF, Furtmüller PG, Obinger C.

Arch Biochem Biophys. 2015 May 15;574:108-19. doi: 10.1016/j.abb.2014.12.025. Epub 2015 Jan 7.

47.

Small high-density lipoprotein is associated with monocyte subsets in stable coronary artery disease.

Krychtiuk KA, Kastl SP, Pfaffenberger S, Pongratz T, Hofbauer SL, Wonnerth A, Katsaros KM, Goliasch G, Gaspar L, Huber K, Maurer G, Dostal E, Oravec S, Wojta J, Speidl WS.

Atherosclerosis. 2014 Dec;237(2):589-96. doi: 10.1016/j.atherosclerosis.2014.10.015. Epub 2014 Oct 18.

48.

The T309G murine double minute 2 gene polymorphism is an independent prognostic factor for patients with renal cell carcinoma.

de Martino M, Taus C, Wessely IS, Lucca I, Hofbauer SL, Haitel A, Shariat SF, Klatte T.

DNA Cell Biol. 2015 Feb;34(2):107-12. doi: 10.1089/dna.2014.2653. Epub 2014 Nov 21.

PMID:
25415135
49.

The preoperative prognostic nutritional index is an independent predictor of survival in patients with renal cell carcinoma.

Hofbauer SL, Pantuck AJ, de Martino M, Lucca I, Haitel A, Shariat SF, Belldegrun AS, Klatte T.

Urol Oncol. 2015 Feb;33(2):68.e1-7. doi: 10.1016/j.urolonc.2014.08.005. Epub 2014 Sep 16.

PMID:
25240758
50.

Associations between presenting symptoms, clinicopathological parameters, and prognosis in a contemporary series of patients with renal cell carcinoma.

Hofbauer SL, de Martino M, Seemann C, Zamani N, Lucca I, Haitel A, Shariat SF, Klatte T.

Korean J Urol. 2014 Aug;55(8):505-10. doi: 10.4111/kju.2014.55.8.505. Epub 2014 Aug 8.

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