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Association between sleep disordered breathing and epigenetic age acceleration: Evidence from the Multi-Ethnic Study of Atherosclerosis.

Li X, Joehanes R, Hoeschele I, Rich SS, Rotter JI, Levy D, Liu Y, Redline S, Sofer T.

EBioMedicine. 2019 Nov 21. pii: S2352-3964(19)30769-8. doi: 10.1016/j.ebiom.2019.11.020. [Epub ahead of print]


Adrenocortical Challenge Response and Genomic Analyses in Scottish Terriers With Increased Alkaline Phosphate Activity.

Zimmerman KL, Panciera DL, Hoeschele I, Monroe WE, Todd SM, Werre SR, LeRoith T, Fecteau K, Lake BB.

Front Vet Sci. 2018 Oct 9;5:231. doi: 10.3389/fvets.2018.00231. eCollection 2018.


Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma.

Connolly NP, Shetty AC, Stokum JA, Hoeschele I, Siegel MB, Miller CR, Kim AJ, Ho CY, Davila E, Simard JM, Devine SE, Rossmeisl JH, Holland EC, Winkles JA, Woodworth GF.

Sci Rep. 2018 Jan 19;8(1):1180. doi: 10.1038/s41598-018-19451-6.


Cell Cycle Model System for Advancing Cancer Biomarker Research.

Lazar IM, Hoeschele I, de Morais J, Tenga MJ.

Sci Rep. 2017 Dec 21;7(1):17989. doi: 10.1038/s41598-017-17845-6.


Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis.

Liu Y, Reynolds LM, Ding J, Hou L, Lohman K, Young T, Cui W, Huang Z, Grenier C, Wan M, Stunnenberg HG, Siscovick D, Hou L, Psaty BM, Rich SS, Rotter JI, Kaufman JD, Burke GL, Murphy S, Jacobs DR Jr, Post W, Hoeschele I, Bell DA, Herrington D, Parks JS, Tracy RP, McCall CE, Stein JH.

Nat Commun. 2017 Aug 30;8(1):393. doi: 10.1038/s41467-017-00517-4.


Secondhand Tobacco Smoke Exposure Associations With DNA Methylation of the Aryl Hydrocarbon Receptor Repressor.

Reynolds LM, Magid HS, Chi GC, Lohman K, Barr RG, Kaufman JD, Hoeschele I, Blaha MJ, Navas-Acien A, Liu Y.

Nicotine Tob Res. 2017 Apr 1;19(4):442-451. doi: 10.1093/ntr/ntw219.


DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical Atherosclerosis.

Reynolds LM, Wan M, Ding J, Taylor JR, Lohman K, Su D, Bennett BD, Porter DK, Gimple R, Pittman GS, Wang X, Howard TD, Siscovick D, Psaty BM, Shea S, Burke GL, Jacobs DR Jr, Rich SS, Hixson JE, Stein JH, Stunnenberg H, Barr RG, Kaufman JD, Post WS, Hoeschele I, Herrington DM, Bell DA, Liu Y.

Circ Cardiovasc Genet. 2015 Oct;8(5):707-16. doi: 10.1161/CIRCGENETICS.115.001097. Epub 2015 Aug 25.


Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease.

Ding J, Reynolds LM, Zeller T, Müller C, Lohman K, Nicklas BJ, Kritchevsky SB, Huang Z, de la Fuente A, Soranzo N, Settlage RE, Chuang CC, Howard T, Xu N, Goodarzi MO, Chen YD, Rotter JI, Siscovick DS, Parks JS, Murphy S, Jacobs DR Jr, Post W, Tracy RP, Wild PS, Blankenberg S, Hoeschele I, Herrington D, McCall CE, Liu Y.

Diabetes. 2015 Oct;64(10):3464-74. doi: 10.2337/db14-1314. Epub 2015 Jul 7.


Transcriptomic profiles of aging in purified human immune cells.

Reynolds LM, Ding J, Taylor JR, Lohman K, Soranzo N, de la Fuente A, Liu TF, Johnson C, Barr RG, Register TC, Donohue KM, Talor MV, Cihakova D, Gu C, Divers J, Siscovick D, Burke G, Post W, Shea S, Jacobs DR Jr, Hoeschele I, McCall CE, Kritchevsky SB, Herrington D, Tracy RP, Liu Y.

BMC Genomics. 2015 Apr 22;16:333. doi: 10.1186/s12864-015-1522-4.


Age-related variations in the methylome associated with gene expression in human monocytes and T cells.

Reynolds LM, Taylor JR, Ding J, Lohman K, Johnson C, Siscovick D, Burke G, Post W, Shea S, Jacobs DR Jr, Stunnenberg H, Kritchevsky SB, Hoeschele I, McCall CE, Herrington D, Tracy RP, Liu Y.

Nat Commun. 2014 Nov 18;5:5366. doi: 10.1038/ncomms6366.


Penalized multimarker vs. single-marker regression methods for genome-wide association studies of quantitative traits.

Yi H, Breheny P, Imam N, Liu Y, Hoeschele I.

Genetics. 2015 Jan;199(1):205-22. doi: 10.1534/genetics.114.167817. Epub 2014 Oct 28.


Methylomics of gene expression in human monocytes.

Liu Y, Ding J, Reynolds LM, Lohman K, Register TC, De La Fuente A, Howard TD, Hawkins GA, Cui W, Morris J, Smith SG, Barr RG, Kaufman JD, Burke GL, Post W, Shea S, McCall CE, Siscovick D, Jacobs DR Jr, Tracy RP, Herrington DM, Hoeschele I.

Hum Mol Genet. 2013 Dec 15;22(24):5065-74. doi: 10.1093/hmg/ddt356. Epub 2013 Jul 29.


Simulating systems genetics data with SysGenSIM.

Pinna A, Soranzo N, Hoeschele I, de la Fuente A.

Bioinformatics. 2011 Sep 1;27(17):2459-62. doi: 10.1093/bioinformatics/btr407. Epub 2011 Jul 6.


Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature.

Galindo CL, McIver LJ, Tae H, McCormick JF, Skinner MA, Hoeschele I, Lewis CM, Minna JD, Boothman DA, Garner HR.

Genes Chromosomes Cancer. 2011 Apr;50(4):275-83. doi: 10.1002/gcc.20853. Epub 2011 Jan 14.


Nonparametric Bayesian variable selection with applications to multiple quantitative trait loci mapping with epistasis and gene-environment interaction.

Zou F, Huang H, Lee S, Hoeschele I.

Genetics. 2010 Sep;186(1):385-94. doi: 10.1534/genetics.109.113688. Epub 2010 Jun 15.


Genome scan for loci regulating HDL cholesterol levels in Finnish extended pedigrees with early coronary heart disease.

Kangas-Kontio T, Kakko S, Tamminen M, von Rohr P, Hoeschele I, Juvonen T, Kere J, Savolainen MJ.

Eur J Hum Genet. 2010 May;18(5):604-13. doi: 10.1038/ejhg.2009.202. Epub 2009 Nov 25.


Gaussian process based bayesian semiparametric quantitative trait Loci interval mapping.

Huang H, Zhou H, Cheng F, Hoeschele I, Zou F.

Biometrics. 2010 Mar;66(1):222-32. doi: 10.1111/j.1541-0420.2009.01268.x. Epub 2009 May 12.


Differential protein expression analysis using stable isotope labeling and PQD linear ion trap MS technology.

Armenta JM, Hoeschele I, Lazar IM.

J Am Soc Mass Spectrom. 2009 Jul;20(7):1287-302. doi: 10.1016/j.jasms.2009.02.029. Epub 2009 Mar 4.


Haplotyping methods for pedigrees.

Gao G, Allison DB, Hoeschele I.

Hum Hered. 2009;67(4):248-66. doi: 10.1159/000194978. Epub 2009 Jan 27. Review.


Infection and genotype remodel the entire soybean transcriptome.

Zhou L, Mideros SX, Bao L, Hanlon R, Arredondo FD, Tripathy S, Krampis K, Jerauld A, Evans C, St Martin SK, Maroof MA, Hoeschele I, Dorrance AE, Tyler BM.

BMC Genomics. 2009 Jan 26;10:49. doi: 10.1186/1471-2164-10-49.


Gene network inference via structural equation modeling in genetical genomics experiments.

Liu B, de la Fuente A, Hoeschele I.

Genetics. 2008 Mar;178(3):1763-76. doi: 10.1534/genetics.107.080069. Epub 2008 Feb 3.


A rapid conditional enumeration haplotyping method in pedigrees.

Gao G, Hoeschele I.

Genet Sel Evol. 2008 Jan-Feb;40(1):25-36. Epub 2007 Dec 21.


Influence of priors in Bayesian estimation of genetic parameters for multivariate threshold models using Gibbs sampling.

Stock KF, Distl O, Hoeschele I.

Genet Sel Evol. 2007 Mar-Apr;39(2):123-37. Epub 2007 Feb 17.


Nucleoplasmin facilitates reprogramming and in vivo development of bovine nuclear transfer embryos.

Betthauser JM, Pfister-Genskow M, Xu H, Golueke PJ, Lacson JC, Koppang RW, Myers C, Liu B, Hoeschele I, Eilertsen KJ, Leno GH.

Mol Reprod Dev. 2006 Aug;73(8):977-86.


Approximating identity-by-descent matrices using multiple haplotype configurations on pedigrees.

Gao G, Hoeschele I.

Genetics. 2005 Sep;171(1):365-76. Epub 2005 Jun 18.


Finite mixture model analysis of microarray expression data on samples of uncertain biological type with application to reproductive efficiency.

Bing N, Hoeschele I, Ye K, Eilertsen KJ.

Vet Immunol Immunopathol. 2005 May 15;105(3-4):187-96.


Genetical genomics analysis of a yeast segregant population for transcription network inference.

Bing N, Hoeschele I.

Genetics. 2005 Jun;170(2):533-42. Epub 2005 Mar 21.


Identification of differentially expressed genes in individual bovine preimplantation embryos produced by nuclear transfer: improper reprogramming of genes required for development.

Pfister-Genskow M, Myers C, Childs LA, Lacson JC, Patterson T, Betthauser JM, Goueleke PJ, Koppang RW, Lange G, Fisher P, Watt SR, Forsberg EJ, Zheng Y, Leno GH, Schultz RM, Liu B, Chetia C, Yang X, Hoeschele I, Eilertsen KJ.

Biol Reprod. 2005 Mar;72(3):546-55. Epub 2004 Oct 13.


Conditional probability methods for haplotyping in pedigrees.

Gao G, Hoeschele I, Sorensen P, Du F.

Genetics. 2004 Aug;167(4):2055-65.


Discovery of meaningful associations in genomic data using partial correlation coefficients.

de la Fuente A, Bing N, Hoeschele I, Mendes P.

Bioinformatics. 2004 Dec 12;20(18):3565-74. Epub 2004 Jul 29.


Search for pleiotropic QTL on chromosome BTA6 affecting yield traits of milk production.

Freyer G, Sørensen P, Kühn C, Weikard R, Hoeschele I.

J Dairy Sci. 2003 Mar;86(3):999-1008.


ATP-binding cassette transporter A1 locus is not a major determinant of HDL-C levels in a population at high risk for coronary heart disease.

Kakko S, Kelloniemi J, von Rohr P, Hoeschele I, Tamminen M, Brousseau ME, Kesäniemi YA, Savolainen MJ.

Atherosclerosis. 2003 Feb;166(2):285-90.


Bayesian QTL mapping using skewed Student-t distributions.

von Rohr P, Hoeschele I.

Genet Sel Evol. 2002 Jan-Feb;34(1):1-21.


Fine-mapping of quantitative trait loci in half-sib families using current recombinations.

Thaller G, Hoeschele I.

Genet Res. 2000 Aug;76(1):87-104.


Mapping quantitative trait loci for milk production and health of dairy cattle in a large outbred pedigree.

Zhang Q, Boichard D, Hoeschele I, Ernst C, Eggen A, Murkve B, Pfister-Genskow M, Witte LA, Grignola FE, Uimari P, Thaller G, Bishop MD.

Genetics. 1998 Aug;149(4):1959-73. Erratum in: Genetics 1999 Sep;153(1):513.


Advances in statistical methods to map quantitative trait loci in outbred populations.

Hoeschele I, Uimari P, Grignola FE, Zhang Q, Gage KM.

Genetics. 1997 Nov;147(3):1445-57.


A Monte Carlo method for Bayesian analysis of linkage between single markers and quantitative trait loci. II. A simulation study.

Thaller G, Hoeschele I.

Theor Appl Genet. 1996 Nov;93(7):1167-74. doi: 10.1007/BF00230142.


A Monte Carlo method for Bayesian analysis of linkage between single markers and quantitative trait loci. I. Methodology.

Thaller G, Hoeschele I.

Theor Appl Genet. 1996 Nov;93(7):1161-6. doi: 10.1007/BF00230141.


The use of multiple markers in a Bayesian method for mapping quantitative trait loci.

Uimari P, Thaller G, Hoeschele I.

Genetics. 1996 Aug;143(4):1831-42.


Maximum likelihood analysis of rare binary traits under different modes of inheritance.

Thaller G, Dempfle L, Hoeschele I.

Genetics. 1996 Aug;143(4):1819-29.


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