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Items: 19


Protein kinase D up-regulates transcription of VEGF receptor-2 in endothelial cells by suppressing nuclear localization of the transcription factor AP2β.

Wang Y, Hoeppner LH, Angom RS, Wang E, Dutta S, Doeppler HR, Wang F, Shen T, Scarisbrick IA, Guha S, Storz P, Bhattacharya R, Mukhopadhyay D.

J Biol Chem. 2019 Oct 25;294(43):15759-15767. doi: 10.1074/jbc.RA119.010152. Epub 2019 Sep 6.


ScanNeo: identifying indel-derived neoantigens using RNA-Seq data.

Wang TY, Wang L, Alam SK, Hoeppner LH, Yang R.

Bioinformatics. 2019 Oct 15;35(20):4159-4161. doi: 10.1093/bioinformatics/btz193.


BMI1 Drives Metastasis of Prostate Cancer in Caucasian and African-American Men and Is A Potential Therapeutic Target: Hypothesis Tested in Race-specific Models.

Ganaie AA, Beigh FH, Astone M, Ferrari MG, Maqbool R, Umbreen S, Parray AS, Siddique HR, Hussain T, Murugan P, Morrissey C, Koochekpour S, Deng Y, Konety BR, Hoeppner LH, Saleem M.

Clin Cancer Res. 2018 Dec 15;24(24):6421-6432. doi: 10.1158/1078-0432.CCR-18-1394. Epub 2018 Aug 7.


DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration.

Alam SK, Astone M, Liu P, Hall SR, Coyle AM, Dankert EN, Hoffman DK, Zhang W, Kuang R, Roden AC, Mansfield AS, Hoeppner LH.

Commun Biol. 2018;1:43. doi: 10.1038/s42003-018-0050-6. Epub 2018 May 3.


Correction: RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells (doi:10.1242/jcs.167601).

Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D.

J Cell Sci. 2018 Mar 16;131(6). pii: jcs217604. doi: 10.1242/jcs.217604. No abstract available.


Fishing for cures: The alLURE of using zebrafish to develop precision oncology therapies.

Astone M, Dankert EN, Alam SK, Hoeppner LH.

NPJ Precis Oncol. 2017;1. pii: 39. doi: 10.1038/s41698-017-0043-9. Epub 2017 Nov 27.


RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells.

Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D.

J Cell Sci. 2015 Oct 1;128(19):3556-68. doi: 10.1242/jcs.167601. Epub 2015 Jul 1. Erratum in: J Cell Sci. 2018 Mar 16;131(6):.


Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis.

Wang Y, Cao Y, Yamada S, Thirunavukkarasu M, Nin V, Joshi M, Rishi MT, Bhattacharya S, Camacho-Pereira J, Sharma AK, Shameer K, Kocher JP, Sanchez JA, Wang E, Hoeppner LH, Dutta SK, Leof EB, Shah V, Claffey KP, Chini EN, Simons M, Terzic A, Maulik N, Mukhopadhyay D.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1401-12. doi: 10.1161/ATVBAHA.115.305566. Epub 2015 Apr 16.


Dopamine D2 receptor agonists inhibit lung cancer progression by reducing angiogenesis and tumor infiltrating myeloid derived suppressor cells.

Hoeppner LH, Wang Y, Sharma A, Javeed N, Van Keulen VP, Wang E, Yang P, Roden AC, Peikert T, Molina JR, Mukhopadhyay D.

Mol Oncol. 2015 Jan;9(1):270-81. doi: 10.1016/j.molonc.2014.08.008. Epub 2014 Aug 30.


Neuropilin-2 promotes extravasation and metastasis by interacting with endothelial α5 integrin.

Cao Y, Hoeppner LH, Bach S, E G, Guo Y, Wang E, Wu J, Cowley MJ, Chang DK, Waddell N, Grimmond SM, Biankin AV, Daly RJ, Zhang X, Mukhopadhyay D.

Cancer Res. 2013 Jul 15;73(14):4579-4590. doi: 10.1158/0008-5472.CAN-13-0529. Epub 2013 May 20.


Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability.

Hoeppner LH, Phoenix KN, Clark KJ, Bhattacharya R, Gong X, Sciuto TE, Vohra P, Suresh S, Bhattacharya S, Dvorak AM, Ekker SC, Dvorak HF, Claffey KP, Mukhopadhyay D.

Blood. 2012 Sep 13;120(11):2167-73. doi: 10.1182/blood-2012-03-417824. Epub 2012 Jun 6.


Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury.

Vohra PK, Hoeppner LH, Sagar G, Dutta SK, Misra S, Hubmayr RD, Mukhopadhyay D.

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 15;302(2):L185-92. doi: 10.1152/ajplung.00274.2010. Epub 2011 Oct 14.


Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass.

Hoeppner LH, Secreto FJ, Razidlo DF, Whitney TJ, Westendorf JJ.

J Biol Chem. 2011 Apr 1;286(13):10950-9. doi: 10.1074/jbc.M110.165100. Epub 2011 Jan 26.


Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation.

Hoeppner LH, Secreto F, Jensen ED, Li X, Kahler RA, Westendorf JJ.

J Cell Physiol. 2009 Nov;221(2):480-9. doi: 10.1002/jcp.21879.


Wnt signaling during fracture repair.

Secreto FJ, Hoeppner LH, Westendorf JJ.

Curr Osteoporos Rep. 2009 Jul;7(2):64-9. Review.


Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors.

Li X, Hoeppner LH, Jensen ED, Gopalakrishnan R, Westendorf JJ.

J Cell Biochem. 2009 Oct 1;108(2):378-87. doi: 10.1002/jcb.22263.


Wnt signaling as a therapeutic target for bone diseases.

Hoeppner LH, Secreto FJ, Westendorf JJ.

Expert Opin Ther Targets. 2009 Apr;13(4):485-96. doi: 10.1517/14728220902841961 . Review.


Collagen 11a1 is indirectly activated by lymphocyte enhancer-binding factor 1 (Lef1) and negatively regulates osteoblast maturation.

Kahler RA, Yingst SM, Hoeppner LH, Jensen ED, Krawczak D, Oxford JT, Westendorf JJ.

Matrix Biol. 2008 May;27(4):330-8. doi: 10.1016/j.matbio.2008.01.002. Epub 2008 Jan 16.


Humoral immune responses to testis antigens in sera from patients with prostate cancer.

Hoeppner LH, Dubovsky JA, Dunphy EJ, McNeel DG.

Cancer Immun. 2006 Jan 10;6:1.

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