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Items: 1 to 50 of 267

1.

Renal Klotho is Reduced in Septic Patients and Pretreatment With Recombinant Klotho Attenuates Organ Injury in Lipopolysaccharide-Challenged Mice.

Jou-Valencia D, Molema G, Popa E, Aslan A, van Dijk F, Mencke R, Hillebrands JL, Heeringa P, Hoenderop JG, Zijlstra JG, van Meurs M, Moser J.

Crit Care Med. 2018 Sep 19. doi: 10.1097/CCM.0000000000003427. [Epub ahead of print]

PMID:
30239382
2.

Uromodulin regulates renal magnesium homeostasis through the ion channel transient receptor potential melastatin 6 (TRPM6).

Nie M, Bal MS, Liu J, Yang Z, Rivera C, Wu XR, Hoenderop JGJ, Bindels RJM, Marciano DK, Wolf MTF.

J Biol Chem. 2018 Aug 23. pii: jbc.RA118.003950. doi: 10.1074/jbc.RA118.003950. [Epub ahead of print]

3.

FGF23 impairs peripheral microvascular function in renal failure.

Verkaik M, Juni RP, van Loon EPM, van Poelgeest E, Kwekkeboom RFJ, Gam Z, Richards WG, Ter Wee PM, Hoenderop JGJ, Eringa EC, Vervloet MG.

Am J Physiol Heart Circ Physiol. 2018 Jul 20. doi: 10.1152/ajpheart.00272.2018. [Epub ahead of print]

PMID:
30028196
4.

Magnesium deficiency prevents high-fat-diet-induced obesity in mice.

Kurstjens S, van Diepen JA, Overmars-Bos C, Alkema W, Bindels RJM, Ashcroft FM, Tack CJJ, Hoenderop JGJ, de Baaij JHF.

Diabetologia. 2018 Jul 9. doi: 10.1007/s00125-018-4680-5. [Epub ahead of print]

5.

Routine hemodialysis induces a decline in plasma magnesium concentration in most patients: a prospective observational cohort study.

Leenders NHJ, van Ittersum FJ, Hoekstra T, Hoenderop JGJ, Vervloet MG.

Sci Rep. 2018 Jul 6;8(1):10256. doi: 10.1038/s41598-018-28629-x.

6.

Recellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity Screening.

Fedecostante M, Westphal KGC, Buono MF, Sanchez Romero N, Wilmer MJ, Kerkering J, Baptista PM, Hoenderop JG, Masereeuw R.

Drug Metab Dispos. 2018 Sep;46(9):1338-1350. doi: 10.1124/dmd.118.080721. Epub 2018 Jul 6.

PMID:
29980578
7.

Polycystin-1 dysfunction impairs electrolyte and water handling in a renal precystic mouse model for ADPKD.

Verschuren EHJ, Mohammed SG, Leonhard WN, Overmars-Bos C, Veraar K, Hoenderop JGJ, Bindels RJM, Peters DJM, Arjona FJ.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F537-F546. doi: 10.1152/ajprenal.00622.2017. Epub 2018 May 16.

PMID:
29767557
8.

Transcription factor HNF1β regulates expression of the calcium-sensing receptor in the thick ascending limb of the kidney.

Kompatscher A, de Baaij JHF, Aboudehen K, Farahani S, van Son LHJ, Milatz S, Himmerkus N, Veenstra GC, Bindels RJM, Hoenderop JGJ.

Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F27-F35. doi: 10.1152/ajprenal.00601.2017. Epub 2018 Mar 21.

PMID:
29561186
9.

Dominant functional role of the novel phosphorylation site S811 in the human renal NaCl cotransporter.

Tutakhel OAZ, Bianchi F, Smits DA, Bindels RJM, Hoenderop JGJ, van der Wijst J.

FASEB J. 2018 Aug;32(8):4482-4493. doi: 10.1096/fj.201701047R. Epub 2018 Mar 16.

PMID:
29547703
10.

Primary cilia-regulated transcriptome in the renal collecting duct.

Mohammed SG, Arjona FJ, Verschuren EHJ, Bakey Z, Alkema W, van Hijum S, Schmidts M, Bindels RJM, Hoenderop JGJ.

FASEB J. 2018 Jul;32(7):3653-3668. doi: 10.1096/fj.201701228R. Epub 2018 Feb 8.

PMID:
29452568
11.

The rise and fall of novel renal magnesium transporters.

Schäffers OJM, Hoenderop JGJ, Bindels RJM, de Baaij JHF.

Am J Physiol Renal Physiol. 2018 Jun 1;314(6):F1027-F1033. doi: 10.1152/ajprenal.00634.2017. Epub 2018 Feb 7.

PMID:
29412701
12.

Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.

Ter Braake AD, Tinnemans PT, Shanahan CM, Hoenderop JGJ, de Baaij JHF.

Sci Rep. 2018 Feb 1;8(1):2069. doi: 10.1038/s41598-018-20241-3.

13.

Effects of a high-sodium/low-potassium diet on renal calcium, magnesium, and phosphate handling.

van der Wijst J, Tutakhel OAZ, Bos C, Danser AHJ, Hoorn EJ, Hoenderop JGJ, Bindels RJM.

Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F110-F122. doi: 10.1152/ajprenal.00379.2017. Epub 2018 Jan 10.

PMID:
29357414
14.

Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes.

Corre T, Arjona FJ, Hayward C, Youhanna S, de Baaij JHF, Belge H, Nägele N, Debaix H, Blanchard MG, Traglia M, Harris SE, Ulivi S, Rueedi R, Lamparter D, Macé A, Sala C, Lenarduzzi S, Ponte B, Pruijm M, Ackermann D, Ehret G, Baptista D, Polasek O, Rudan I, Hurd TW, Hastie ND, Vitart V, Waeber G, Kutalik Z, Bergmann S, Vargas-Poussou R, Konrad M, Gasparini P, Deary IJ, Starr JM, Toniolo D, Vollenweider P, Hoenderop JGJ, Bindels RJM, Bochud M, Devuyst O.

J Am Soc Nephrol. 2018 Jan;29(1):335-348. doi: 10.1681/ASN.2017030267. Epub 2017 Nov 1.

PMID:
29093028
15.

Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application.

Mihajlovic M, van den Heuvel LP, Hoenderop JG, Jansen J, Wilmer MJ, Westheim AJF, Allebes WA, Stamatialis D, Hilbrands LB, Masereeuw R.

Sci Rep. 2017 Aug 2;7(1):7103. doi: 10.1038/s41598-017-07582-1.

16.

A Novel Hypokalemic-Alkalotic Salt-Losing Tubulopathy in Patients with CLDN10 Mutations.

Bongers EMHF, Shelton LM, Milatz S, Verkaart S, Bech AP, Schoots J, Cornelissen EAM, Bleich M, Hoenderop JGJ, Wetzels JFM, Lugtenberg D, Nijenhuis T.

J Am Soc Nephrol. 2017 Oct;28(10):3118-3128. doi: 10.1681/ASN.2016080881. Epub 2017 Jul 3.

17.

Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1β drives autosomal dominant tubulointerstitial kidney disease.

Kompatscher A, de Baaij JHF, Aboudehen K, Hoefnagels APWM, Igarashi P, Bindels RJM, Veenstra GJC, Hoenderop JGJ.

Kidney Int. 2017 Nov;92(5):1145-1156. doi: 10.1016/j.kint.2017.03.034. Epub 2017 May 31.

PMID:
28577853
18.

NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity.

Tutakhel OAZ, Moes AD, Valdez-Flores MA, Kortenoeven MLA, Vrie MVD, Jeleń S, Fenton RA, Zietse R, Hoenderop JGJ, Hoorn EJ, Hilbrands L, Bindels RJM.

PLoS One. 2017 Apr 21;12(4):e0176220. doi: 10.1371/journal.pone.0176220. eCollection 2017.

19.

A Gate Hinge Controls the Epithelial Calcium Channel TRPV5.

van der Wijst J, Leunissen EH, Blanchard MG, Venselaar H, Verkaart S, Paulsen CE, Bindels RJ, Hoenderop JG.

Sci Rep. 2017 Apr 4;7:45489. doi: 10.1038/srep45489.

20.

Hydrochlorothiazide treatment increases the abundance of the NaCl cotransporter in urinary extracellular vesicles of essential hypertensive patients.

Pathare G, Tutakhel OAZ, van der Wel MC, Shelton LM, Deinum J, Lenders JWM, Hoenderop JGJ, Bindels RJM.

Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F1063-F1072. doi: 10.1152/ajprenal.00644.2016. Epub 2017 Mar 8.

21.

Differential regulation of the Na+-Ca2+ exchanger 3 (NCX3) by protein kinase PKC and PKA.

Michel LYM, Verkaart S, Latta F, Hoenderop JGJ, Bindels RJM.

Cell Calcium. 2017 Jul;65:52-62. doi: 10.1016/j.ceca.2017.02.005. Epub 2017 Feb 16.

PMID:
28233567
22.

Fluid shear stress increases transepithelial transport of Ca2+ in ciliated distal convoluted and connecting tubule cells.

Mohammed SG, Arjona FJ, Latta F, Bindels RJM, Roepman R, Hoenderop JGJ.

FASEB J. 2017 May;31(5):1796-1806. doi: 10.1096/fj.201600687RRR. Epub 2017 Jan 18.

PMID:
28100643
23.

Common single nucleotide polymorphisms in transient receptor potential melastatin type 6 increase the risk for proton pump inhibitor-induced hypomagnesemia: a case-control study.

Hess MW, de Baaij JH, Broekman MM, Bisseling TM, Haarhuis BJ, Tan AC, Te Morsche RH, Hoenderop JG, Bindels RJ, Drenth JP.

Pharmacogenet Genomics. 2017 Mar;27(3):83-88. doi: 10.1097/FPC.0000000000000259.

PMID:
27926584
24.

TRP channels in calcium homeostasis: from hormonal control to structure-function relationship of TRPV5 and TRPV6.

van Goor MKC, Hoenderop JGJ, van der Wijst J.

Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):883-893. doi: 10.1016/j.bbamcr.2016.11.027. Epub 2016 Nov 30. Review.

25.

Sildenafil Prevents Podocyte Injury via PPAR-γ-Mediated TRPC6 Inhibition.

Sonneveld R, Hoenderop JG, Isidori AM, Henique C, Dijkman HB, Berden JH, Tharaux PL, van der Vlag J, Nijenhuis T.

J Am Soc Nephrol. 2017 May;28(5):1491-1505. doi: 10.1681/ASN.2015080885. Epub 2016 Nov 28.

26.

Determinants of hypomagnesemia in patients with type 2 diabetes mellitus.

Kurstjens S, de Baaij JH, Bouras H, Bindels RJ, Tack CJ, Hoenderop JG.

Eur J Endocrinol. 2017 Jan;176(1):11-19. Epub 2016 Oct 5.

PMID:
27707767
27.

Functionomics of NCC mutations in Gitelman syndrome using a novel mammalian cell-based activity assay.

Valdez-Flores MA, Vargas-Poussou R, Verkaart S, Tutakhel OA, Valdez-Ortiz A, Blanchard A, Treard C, Hoenderop JG, Bindels RJ, Jeleń S.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1159-F1167. doi: 10.1152/ajprenal.00124.2016. Epub 2016 Aug 31.

28.

TRPV4 mediates afferent pathways in the urinary bladder. A spinal c-fos study showing TRPV1 related adaptations in the TRPV4 knockout mouse.

Janssen DA, Hoenderop JG, Heesakkers JP, Schalken JA.

Pflugers Arch. 2016 Oct;468(10):1741-9. doi: 10.1007/s00424-016-1859-9. Epub 2016 Aug 5.

29.

Identification of SLC41A3 as a novel player in magnesium homeostasis.

de Baaij JH, Arjona FJ, van den Brand M, Lavrijsen M, Lameris AL, Bindels RJ, Hoenderop JG.

Sci Rep. 2016 Jun 28;6:28565. doi: 10.1038/srep28565.

30.

P2X6 Knockout Mice Exhibit Normal Electrolyte Homeostasis.

de Baaij JH, Kompatscher A, Viering DH, Bos C, Bindels RJ, Hoenderop JG.

PLoS One. 2016 Jun 2;11(6):e0156803. doi: 10.1371/journal.pone.0156803. eCollection 2016.

31.

Bioengineered kidney tubules efficiently excrete uremic toxins.

Jansen J, Fedecostante M, Wilmer MJ, Peters JG, Kreuser UM, van den Broek PH, Mensink RA, Boltje TJ, Stamatialis D, Wetzels JF, van den Heuvel LP, Hoenderop JG, Masereeuw R.

Sci Rep. 2016 May 31;6:26715. doi: 10.1038/srep26715.

32.

Fibroblast growth factor 23 modifies the pharmacological effects of angiotensin receptor blockade in experimental renal fibrosis.

de Jong MA, Mirkovic K, Mencke R, Hoenderop JG, Bindels RJ, Vervloet MG, Hillebrands JL, van den Born J, Navis G, de Borst MH; NIGRAM consortium.

Nephrol Dial Transplant. 2017 Jan 1;32(1):73-80. doi: 10.1093/ndt/gfw105.

PMID:
27220755
33.

TRPV4 channels in the human urogenital tract play a role in cell junction formation and epithelial barrier.

Janssen DA, Jansen CJ, Hafmans TG, Verhaegh GW, Hoenderop JG, Heesakkers JP, Schalken JA.

Acta Physiol (Oxf). 2016 Sep;218(1):38-48. doi: 10.1111/apha.12701. Epub 2016 May 25.

PMID:
27124500
34.

Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism.

van der Eerden BC, Koek WN, Roschger P, Zillikens MC, Waarsing JH, van der Kemp A, Schreuders-Koedam M, Fratzl-Zelman N, Leenen PJ, Hoenderop JG, Klaushofer K, Bindels RJ, van Leeuwen JP.

Oncotarget. 2016 May 3;7(18):24928-41. doi: 10.18632/oncotarget.8779.

35.

Calcium Extrusion Pump PMCA4: A New Player in Renal Calcium Handling?

van Loon EP, Little R, Prehar S, Bindels RJ, Cartwright EJ, Hoenderop JG.

PLoS One. 2016 Apr 21;11(4):e0153483. doi: 10.1371/journal.pone.0153483. eCollection 2016.

36.

Inulin significantly improves serum magnesium levels in proton pump inhibitor-induced hypomagnesaemia.

Hess MW, de Baaij JH, Broekman M, Bisseling TM, Haarhuis B, Tan A, Te Morsche R, Hoenderop JG, Bindels RJ, Drenth JP.

Aliment Pharmacol Ther. 2016 Jun;43(11):1178-85. doi: 10.1111/apt.13619. Epub 2016 Apr 18.

37.

Inhibition of PRL-2·CNNM3 Protein Complex Formation Decreases Breast Cancer Proliferation and Tumor Growth.

Kostantin E, Hardy S, Valinsky WC, Kompatscher A, de Baaij JH, Zolotarov Y, Landry M, Uetani N, Martínez-Cruz LA, Hoenderop JG, Shrier A, Tremblay ML.

J Biol Chem. 2016 May 13;291(20):10716-25. doi: 10.1074/jbc.M115.705863. Epub 2016 Mar 11.

38.

1,25-Vitamin D3 Deficiency Induces Albuminuria.

Sonneveld R, Hoenderop JG, Stavenuiter AW, Ferrantelli E, Baltissen MP, Dijkman HB, Florquin S, Rops AL, Wetzels JF, Berden JH, van der Vlag J, Nijenhuis T.

Am J Pathol. 2016 Apr;186(4):794-804. doi: 10.1016/j.ajpath.2015.11.015. Epub 2016 Feb 3.

PMID:
26851346
39.

Reduction of Oxidative Stress in Chronic Kidney Disease Does Not Increase Circulating α-Klotho Concentrations.

Adema AY, van Ittersum FJ, Hoenderop JG, de Borst MH, Nanayakkara PW, Ter Wee PM, Heijboer AC, Vervloet MG; NIGRAM consortium.

PLoS One. 2016 Jan 25;11(1):e0144121. doi: 10.1371/journal.pone.0144121. eCollection 2016.

40.

Urinary β-galactosidase stimulates Ca2+ transport by stabilizing TRPV5 at the plasma membrane.

Leunissen EH, Blanchard MG, Sheedfar F, Lavrijsen M, van der Wijst J, Bindels RJ, Hoenderop JG.

Glycobiology. 2016 May;26(5):472-81. doi: 10.1093/glycob/cwv172. Epub 2016 Jan 7.

PMID:
26747426
41.

Hypomagnesemia in Type 2 Diabetes: A Vicious Circle?

Gommers LM, Hoenderop JG, Bindels RJ, de Baaij JH.

Diabetes. 2016 Jan;65(1):3-13. doi: 10.2337/db15-1028. Review.

42.

Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations.

Jansen J, De Napoli IE, Fedecostante M, Schophuizen CM, Chevtchik NV, Wilmer MJ, van Asbeck AH, Croes HJ, Pertijs JC, Wetzels JF, Hilbrands LB, van den Heuvel LP, Hoenderop JG, Stamatialis D, Masereeuw R.

Sci Rep. 2015 Nov 16;5:16702. doi: 10.1038/srep16702.

43.

Deregulated Renal Calcium and Phosphate Transport during Experimental Kidney Failure.

Pulskens WP, Verkaik M, Sheedfar F, van Loon EP, van de Sluis B, Vervloet MG, Hoenderop JG, Bindels RJ; NIGRAM Consortium.

PLoS One. 2015 Nov 13;10(11):e0142510. doi: 10.1371/journal.pone.0142510. eCollection 2015.

44.

Alternative splice variant of the thiazide-sensitive NaCl cotransporter: a novel player in renal salt handling.

Tutakhel OA, Jeleń S, Valdez-Flores M, Dimke H, Piersma SR, Jimenez CR, Deinum J, Lenders JW, Hoenderop JG, Bindels RJ.

Am J Physiol Renal Physiol. 2016 Feb 1;310(3):F204-16. doi: 10.1152/ajprenal.00429.2015. Epub 2015 Nov 11.

45.

Calpain-3-mediated regulation of the Na⁺-Ca²⁺ exchanger isoform 3.

Michel LY, Hoenderop JG, Bindels RJ.

Pflugers Arch. 2016 Feb;468(2):243-55. doi: 10.1007/s00424-015-1747-8. Epub 2015 Oct 27.

46.

The Na+/Ca2+ Exchanger 1 (NCX1) Variant 3 as the Major Extrusion System in Renal Distal Tubular Transcellular Ca2+-Transport.

van der Hagen EA, van Loon EP, Verkaart S, Latta F, Bindels RJ, Hoenderop JG.

Nephron. 2015;131(2):145-52. doi: 10.1159/000440655. Epub 2015 Sep 30.

PMID:
26418956
47.

Dietary Inulin Fibers Prevent Proton-Pump Inhibitor (PPI)-Induced Hypocalcemia in Mice.

Hess MW, de Baaij JH, Gommers LM, Hoenderop JG, Bindels RJ.

PLoS One. 2015 Sep 23;10(9):e0138881. doi: 10.1371/journal.pone.0138881. eCollection 2015.

48.

Hypomagnesemia as First Clinical Manifestation of ADTKD-HNF1B: A Case Series and Literature Review.

van der Made CI, Hoorn EJ, de la Faille R, Karaaslan H, Knoers NV, Hoenderop JG, Vargas Poussou R, de Baaij JH.

Am J Nephrol. 2015;42(1):85-90. Review.

49.

Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology.

Mutsaers HA, Caetano-Pinto P, Seegers AE, Dankers AC, van den Broek PH, Wetzels JF, van den Brand JA, van den Heuvel LP, Hoenderop JG, Wilmer MJ, Masereeuw R.

Toxicol In Vitro. 2015 Oct;29(7):1868-77. doi: 10.1016/j.tiv.2015.07.020. Epub 2015 Jul 26.

PMID:
26216510
50.

Vitamin D attenuates proteinuria by inhibition of heparanase expression in the podocyte.

Garsen M, Sonneveld R, Rops AL, Huntink S, van Kuppevelt TH, Rabelink TJ, Hoenderop JG, Berden JH, Nijenhuis T, van der Vlag J.

J Pathol. 2015 Dec;237(4):472-81. doi: 10.1002/path.4593. Epub 2015 Aug 31.

PMID:
26202309

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