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Items: 43

1.

The Structure of the Nuclear Pore Complex (An Update).

Lin DH, Hoelz A.

Annu Rev Biochem. 2019 Jun 20;88:725-783. doi: 10.1146/annurev-biochem-062917-011901. Epub 2019 Mar 18.

PMID:
30883195
2.

Structural and functional analysis of mRNA export regulation by the nuclear pore complex.

Lin DH, Correia AR, Cai SW, Huber FM, Jette CA, Hoelz A.

Nat Commun. 2018 Jun 13;9(1):2319. doi: 10.1038/s41467-018-04459-3.

3.

A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model.

Skubák P, Araç D, Bowler MW, Correia AR, Hoelz A, Larsen S, Leonard GA, McCarthy AA, McSweeney S, Mueller-Dieckmann C, Otten H, Salzman G, Pannu NS.

IUCrJ. 2018 Jan 25;5(Pt 2):166-171. doi: 10.1107/S2052252517017961. eCollection 2018 Mar 1.

4.

Günter Blobel (1936-2018).

Hoelz A.

Nat Cell Biol. 2018 Apr;20(4):364. doi: 10.1038/s41556-018-0081-8. No abstract available.

PMID:
29593325
5.

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

Huber FM, Greenblatt SM, Davenport AM, Martinez C, Xu Y, Vu LP, Nimer SD, Hoelz A.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6016-6021. doi: 10.1073/pnas.1700328114. Epub 2017 May 22.

6.

Molecular basis for protection of ribosomal protein L4 from cellular degradation.

Huber FM, Hoelz A.

Nat Commun. 2017 Feb 2;8:14354. doi: 10.1038/ncomms14354.

7.

A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins.

Sung MK, Porras-Yakushi TR, Reitsma JM, Huber FM, Sweredoski MJ, Hoelz A, Hess S, Deshaies RJ.

Elife. 2016 Aug 23;5. pii: e19105. doi: 10.7554/eLife.19105.

8.

Toward the atomic structure of the nuclear pore complex: when top down meets bottom up.

Hoelz A, Glavy JS, Beck M.

Nat Struct Mol Biol. 2016 Jul;23(7):624-30. doi: 10.1038/nsmb.3244. Epub 2016 Jun 6. Review.

9.

Architecture of the symmetric core of the nuclear pore.

Lin DH, Stuwe T, Schilbach S, Rundlet EJ, Perriches T, Mobbs G, Fan Y, Thierbach K, Huber FM, Collins LN, Davenport AM, Jeon YE, Hoelz A.

Science. 2016 Apr 15;352(6283):aaf1015. doi: 10.1126/science.aaf1015. Epub 2016 Apr 14.

10.

Architecture of the fungal nuclear pore inner ring complex.

Stuwe T, Bley CJ, Thierbach K, Petrovic S, Schilbach S, Mayo DJ, Perriches T, Rundlet EJ, Jeon YE, Collins LN, Huber FM, Lin DH, Paduch M, Koide A, Lu V, Fischer J, Hurt E, Koide S, Kossiakoff AA, Hoelz A.

Science. 2015 Oct 2;350(6256):56-64. doi: 10.1126/science.aac9176. Epub 2015 Aug 27.

11.

Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension.

Stelter P, Huber FM, Kunze R, Flemming D, Hoelz A, Hurt E.

Mol Cell. 2015 Jun 4;58(5):854-62. doi: 10.1016/j.molcel.2015.03.029. Epub 2015 Apr 30.

12.

Nuclear pores. Architecture of the nuclear pore complex coat.

Stuwe T, Correia AR, Lin DH, Paduch M, Lu VT, Kossiakoff AA, Hoelz A.

Science. 2015 Mar 6;347(6226):1148-52. doi: 10.1126/science.aaa4136. Epub 2015 Feb 12.

13.

Structural and functional characterization of the α-tubulin acetyltransferase MEC-17.

Davenport AM, Collins LN, Chiu H, Minor PJ, Sternberg PW, Hoelz A.

J Mol Biol. 2014 Jul 15;426(14):2605-16. doi: 10.1016/j.jmb.2014.05.009. Epub 2014 May 17.

14.

Evidence for an evolutionary relationship between the large adaptor nucleoporin Nup192 and karyopherins.

Stuwe T, Lin DH, Collins LN, Hurt E, Hoelz A.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2530-5. doi: 10.1073/pnas.1311081111. Epub 2014 Feb 6.

15.

Structural and functional analysis of human SIRT1.

Davenport AM, Huber FM, Hoelz A.

J Mol Biol. 2014 Feb 6;426(3):526-41. doi: 10.1016/j.jmb.2013.10.009. Epub 2013 Oct 10.

16.

Structural and functional analysis of the C-terminal domain of Nup358/RanBP2.

Lin DH, Zimmermann S, Stuwe T, Stuwe E, Hoelz A.

J Mol Biol. 2013 Apr 26;425(8):1318-29. doi: 10.1016/j.jmb.2013.01.021. Epub 2013 Jan 23.

17.

Crystal structure of the N-terminal domain of Nup358/RanBP2.

Kassube SA, Stuwe T, Lin DH, Antonuk CD, Napetschnig J, Blobel G, Hoelz A.

J Mol Biol. 2012 Nov 9;423(5):752-65. doi: 10.1016/j.jmb.2012.08.026. Epub 2012 Sep 7.

18.

Molecular basis for the anchoring of proto-oncoprotein Nup98 to the cytoplasmic face of the nuclear pore complex.

Stuwe T, von Borzyskowski LS, Davenport AM, Hoelz A.

J Mol Biol. 2012 Jun 22;419(5):330-46. doi: 10.1016/j.jmb.2012.03.024. Epub 2012 Apr 2.

19.

Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex.

Yoshida K, Seo HS, Debler EW, Blobel G, Hoelz A.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16571-6. doi: 10.1073/pnas.1112846108. Epub 2011 Sep 19.

20.

Structure of an enclosed dimer formed by the Drosophila period protein.

King HA, Hoelz A, Crane BR, Young MW.

J Mol Biol. 2011 Oct 28;413(3):561-72. doi: 10.1016/j.jmb.2011.08.048. Epub 2011 Sep 3.

21.

Rae1: a new clue for nucleoporin leukemias.

Stuwe T, Hoelz A.

Cell Cycle. 2011 Jul 1;10(13):2056. Epub 2011 Jul 1. No abstract available.

PMID:
21597329
22.

The structure of the nuclear pore complex.

Hoelz A, Debler EW, Blobel G.

Annu Rev Biochem. 2011;80:613-43. doi: 10.1146/annurev-biochem-060109-151030. Review.

PMID:
21495847
23.

Characterization of the membrane-coating Nup84 complex: paradigm for the nuclear pore complex structure.

Debler EW, Hsia KC, Nagy V, Seo HS, Hoelz A.

Nucleus. 2010 Mar-Apr;1(2):150-7. doi: 10.4161/nucl.1.2.11120. Epub 2010 Jan 3. Review.

24.

Crystal structure of alpha-COP in complex with epsilon-COP provides insight into the architecture of the COPI vesicular coat.

Hsia KC, Hoelz A.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11271-6. doi: 10.1073/pnas.1006297107. Epub 2010 Jun 3.

25.

Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1.

Ren Y, Seo HS, Blobel G, Hoelz A.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10406-11. doi: 10.1073/pnas.1005389107. Epub 2010 May 24.

26.

Structure of a trimeric nucleoporin complex reveals alternate oligomerization states.

Nagy V, Hsia KC, Debler EW, Kampmann M, Davenport AM, Blobel G, Hoelz A.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17693-8. doi: 10.1073/pnas.0909373106. Epub 2009 Oct 1.

27.

Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex.

Seo HS, Ma Y, Debler EW, Wacker D, Kutik S, Blobel G, Hoelz A.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14281-6. doi: 10.1073/pnas.0907453106. Epub 2009 Aug 11.

28.

Nuclear transport comes full circle.

Debler EW, Blobel G, Hoelz A.

Nat Struct Mol Biol. 2009 May;16(5):457-9. doi: 10.1038/nsmb0509-457. No abstract available.

PMID:
19421156
29.

Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19.

Napetschnig J, Kassube SA, Debler EW, Wong RW, Blobel G, Hoelz A.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3089-94. doi: 10.1073/pnas.0813267106. Epub 2009 Feb 10.

30.

A fence-like coat for the nuclear pore membrane.

Debler EW, Ma Y, Seo HS, Hsia KC, Noriega TR, Blobel G, Hoelz A.

Mol Cell. 2008 Dec 26;32(6):815-26. doi: 10.1016/j.molcel.2008.12.001.

31.

Molecular basis for the autoregulation of the protein acetyl transferase Rtt109.

Stavropoulos P, Nagy V, Blobel G, Hoelz A.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12236-41. doi: 10.1073/pnas.0805813105. Epub 2008 Aug 21.

32.

Architecture of a coat for the nuclear pore membrane.

Hsia KC, Stavropoulos P, Blobel G, Hoelz A.

Cell. 2007 Dec 28;131(7):1313-26.

33.

Lysine-specific demethylase 1 as a potential therapeutic target.

Stavropoulos P, Hoelz A.

Expert Opin Ther Targets. 2007 Jun;11(6):809-20. Review.

PMID:
17504018
34.

Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding.

Melcák I, Hoelz A, Blobel G.

Science. 2007 Mar 23;315(5819):1729-32.

35.

Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN.

Napetschnig J, Blobel G, Hoelz A.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1783-8. Epub 2007 Jan 30.

36.

A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.

Pirruccello M, Sondermann H, Pelton JG, Pellicena P, Hoelz A, Chernoff J, Wemmer DE, Kuriyan J.

J Mol Biol. 2006 Aug 11;361(2):312-26. Epub 2006 Jun 27.

PMID:
16837009
37.

Crystal structure and mechanism of human lysine-specific demethylase-1.

Stavropoulos P, Blobel G, Hoelz A.

Nat Struct Mol Biol. 2006 Jul;13(7):626-32. Epub 2006 Jun 25.

PMID:
16799558
38.

Crystal structure of the SH3 domain of betaPIX in complex with a high affinity peptide from PAK2.

Hoelz A, Janz JM, Lawrie SD, Corwin B, Lee A, Sakmar TP.

J Mol Biol. 2006 Apr 28;358(2):509-22. Epub 2006 Feb 28.

PMID:
16527308
39.

Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.

Rosenberg OS, Deindl S, Comolli LR, Hoelz A, Downing KH, Nairn AC, Kuriyan J.

FEBS J. 2006 Feb;273(4):682-94.

40.

Cell biology: popping out of the nucleus.

Hoelz A, Blobel G.

Nature. 2004 Dec 16;432(7019):815-6. No abstract available.

PMID:
15602540
41.
42.

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS.

Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J.

Cell. 2003 Mar 7;112(5):685-95.

43.

Gene structures and properties of enzymes of the plasmid-encoded nicotine catabolism of Arthrobacter nicotinovorans.

Schenk S, Hoelz A, Krauss B, Decker K.

J Mol Biol. 1998 Dec 18;284(5):1323-39.

PMID:
9878353

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