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Items: 22

1.

Deciphering human ribonucleoprotein regulatory networks.

Mukherjee N, Wessels HH, Lebedeva S, Sajek M, Ghanbari M, Garzia A, Munteanu A, Yusuf D, Farazi T, Hoell JI, Akat KM, Akalin A, Tuschl T, Ohler U.

Nucleic Acids Res. 2018 Dec 5. doi: 10.1093/nar/gky1185. [Epub ahead of print]

PMID:
30517751
2.

Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling.

Duggimpudi S, Kloetgen A, Maney SK, Münch PC, Hezaveh K, Shaykhalishahi H, Hoyer W, McHardy AC, Lang PA, Borkhardt A, Hoell JI.

J Biol Chem. 2018 Oct 5;293(40):15359-15369. doi: 10.1074/jbc.RA118.002243. Epub 2018 Aug 20.

PMID:
30126842
3.

The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells.

Ingenhag D, Reister S, Auer F, Bhatia S, Wildenhain S, Picard D, Remke M, Hoell JI, Kloetgen A, Sohn D, Jänicke RU, Koegler G, Borkhardt A, Hauer J.

Haematologica. 2019 Jan;104(1):35-46. doi: 10.3324/haematol.2018.189407. Epub 2018 Aug 9.

4.

Challenges of palliative care in children with inborn metabolic diseases.

Hoell JI, Warfsmann J, Distelmaier F, Borkhardt A, Janßen G, Kuhlen M.

Orphanet J Rare Dis. 2018 Jul 9;13(1):112. doi: 10.1186/s13023-018-0868-5.

5.

Advance care planning and outcome in pediatric palliative home care.

Hoell JI, Weber HL, Balzer S, Danneberg M, Gagnon G, Trocan L, Borkhardt A, Janßen G, Kuhlen M.

Oncotarget. 2018 Apr 3;9(25):17867-17875. doi: 10.18632/oncotarget.24929. eCollection 2018 Apr 3.

6.

Diagnostic challenges in a child with early onset desmoplastic medulloblastoma and homozygous variants in MSH2 and MSH6.

Taeubner J, Wimmer K, Muleris M, Lascols O, Colas C, Fauth C, Brozou T, Felsberg J, Riemer J, Gombert M, Ginzel S, Hoell JI, Borkhardt A, Kuhlen M.

Eur J Hum Genet. 2018 Mar;26(3):440-444. doi: 10.1038/s41431-017-0071-5. Epub 2018 Jan 4.

PMID:
29302048
7.

Outcome of relapse after allogeneic HSCT in children with ALL enrolled in the ALL-SCT 2003/2007 trial.

Kuhlen M, Willasch AM, Dalle JH, Wachowiak J, Yaniv I, Ifversen M, Sedlacek P, Guengoer T, Lang P, Bader P, Sufliarska S, Balduzzi A, Strahm B, von Luettichau I, Hoell JI, Borkhardt A, Klingebiel T, Schrappe M, von Stackelberg A, Glogova E, Poetschger U, Meisel R, Peters C.

Br J Haematol. 2018 Jan;180(1):82-89. doi: 10.1111/bjh.14965. Epub 2017 Nov 28.

PMID:
29193007
8.

End-of-life care in children with hematologic malignancies.

Hoell JI, Warfsmann J, Balzer S, Borkhardt A, Janssen G, Kuhlen M.

Oncotarget. 2017 Sep 23;8(52):89939-89948. doi: 10.18632/oncotarget.21188. eCollection 2017 Oct 27.

9.

Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection.

Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, Crocker PR, Tanaka M, Duggimpudi S, Knolle P, Heikenwalder M, Ruland J, Mak TW, Brenner D, Pandyra AA, Hoell JI, Borkhardt A, Häussinger D, Lang KS, Lang PA.

J Virol. 2018 Jan 17;92(3). pii: e01637-17. doi: 10.1128/JVI.01637-17. Print 2018 Feb 1.

10.

Palliative care for children with a yet undiagnosed syndrome.

Hoell JI, Warfsmann J, Gagnon G, Trocan L, Balzer S, Oommen PT, Borkhardt A, Janßen G, Kuhlen M.

Eur J Pediatr. 2017 Oct;176(10):1319-1327. doi: 10.1007/s00431-017-2991-z. Epub 2017 Aug 14.

PMID:
28808789
11.

The PARA-suite: PAR-CLIP specific sequence read simulation and processing.

Kloetgen A, Borkhardt A, Hoell JI, McHardy AC.

PeerJ. 2016 Oct 27;4:e2619. eCollection 2016.

12.

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis.

Hezaveh K, Kloetgen A, Bernhart SH, Mahapatra KD, Lenze D, Richter J, Haake A, Bergmann AK, Brors B, Burkhardt B, Claviez A, Drexler HG, Eils R, Haas S, Hoffmann S, Karsch D, Klapper W, Kleinheinz K, Korbel J, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Leich E, Loeffler M, Mantovani-Loeffler L, López C, McHardy AC, Möller P, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schlesner M, Scholz I, Stadler PF, Stilgenbauer S, Sungalee S, Szczepanowski M, Trümper L, Weniger MA, Siebert R, Borkhardt A, Hummel M, Hoell JI; ICGC MMML-Seq Project.

Haematologica. 2016 Nov;101(11):1380-1389. Epub 2016 Jul 6.

13.

T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.

Doerrenberg M, Kloetgen A, Hezaveh K, Wössmann W, Bleckmann K, Stanulla M, Schrappe M, McHardy AC, Borkhardt A, Hoell JI.

Genes Chromosomes Cancer. 2017 Feb;56(2):159-167. doi: 10.1002/gcc.22423. Epub 2016 Oct 26.

PMID:
27717083
14.

Effective treatment of spasticity using dronabinol in pediatric palliative care.

Kuhlen M, Hoell JI, Gagnon G, Balzer S, Oommen PT, Borkhardt A, Janßen G.

Eur J Paediatr Neurol. 2016 Nov;20(6):898-903. doi: 10.1016/j.ejpn.2016.07.021. Epub 2016 Jul 30.

PMID:
27506815
15.

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells.

Doose G, Haake A, Bernhart SH, López C, Duggimpudi S, Wojciech F, Bergmann AK, Borkhardt A, Burkhardt B, Claviez A, Dimitrova L, Haas S, Hoell JI, Hummel M, Karsch D, Klapper W, Kleo K, Kretzmer H, Kreuz M, Küppers R, Lawerenz C, Lenze D, Loeffler M, Mantovani-Löffler L, Möller P, Ott G, Richter J, Rohde M, Rosenstiel P, Rosenwald A, Schilhabel M, Schneider M, Scholz I, Stilgenbauer S, Stunnenberg HG, Szczepanowski M, Trümper L, Weniger MA; ICGC MMML-Seq Consortium, Hoffmann S, Siebert R, Iaccarino I.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):E5261-70. doi: 10.1073/pnas.1505753112. Epub 2015 Sep 8.

16.

The cell cycle regulator CCDC6 is a key target of RNA-binding protein EWS.

Duggimpudi S, Larsson E, Nabhani S, Borkhardt A, Hoell JI.

PLoS One. 2015 Mar 9;10(3):e0119066. doi: 10.1371/journal.pone.0119066. eCollection 2015.

17.

Constitutional mismatch repair-deficiency and whole-exome sequencing as the means of the rapid detection of the causative MSH6 defect.

Hoell JI, Gombert M, Ginzel S, Loth S, Landgraf P, Käfer V, Streiter M, Prokop A, Weiss M, Thiele R, Borkhardt A.

Klin Padiatr. 2014 Nov;226(6-7):357-61. doi: 10.1055/s-0034-1389905. Epub 2014 Nov 28.

PMID:
25431869
18.

Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols.

Rohde M, Richter J, Schlesner M, Betts MJ, Claviez A, Bonn BR, Zimmermann M, Damm-Welk C, Russell RB, Borkhardt A, Eils R, Hoell JI, Szczepanowski M, Oschlies I, Klapper W, Burkhardt B, Siebert R; German ICGC MMML-Seq-Project; NHL-BFM Study Group.

Genes Chromosomes Cancer. 2014 Nov;53(11):911-6. doi: 10.1002/gcc.22202. Epub 2014 Jul 8.

PMID:
25044415
19.

Biochemical and bioinformatic methods for elucidating the role of RNA-protein interactions in posttranscriptional regulation.

Kloetgen A, Münch PC, Borkhardt A, Hoell JI, McHardy AC.

Brief Funct Genomics. 2015 Mar;14(2):102-14. doi: 10.1093/bfgp/elu020. Epub 2014 Jun 20. Review.

20.

Whole-genome paired-end analysis confirms remarkable genomic stability of atypical teratoid/rhabdoid tumors.

Hoell JI, Gombert M, Bartenhagen C, Ginzel S, Husemann P, Felsberg J, Reifenberger G, Eggert A, Dugas M, Schönberger S, Borkhardt A, Fischer U.

Genes Chromosomes Cancer. 2013 Oct;52(10):983-5. doi: 10.1002/gcc.22092. Epub 2013 Aug 9. No abstract available.

PMID:
23929726
21.

MicroRNAs in human cancer.

Farazi TA, Hoell JI, Morozov P, Tuschl T.

Adv Exp Med Biol. 2013;774:1-20. doi: 10.1007/978-94-007-5590-1_1. Review.

22.

RNA targets of wild-type and mutant FET family proteins.

Hoell JI, Larsson E, Runge S, Nusbaum JD, Duggimpudi S, Farazi TA, Hafner M, Borkhardt A, Sander C, Tuschl T.

Nat Struct Mol Biol. 2011 Nov 13;18(12):1428-31. doi: 10.1038/nsmb.2163.

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