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Items: 22


Innate CD8αα+ cells promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation.

Nazmi A, Hoek KL, Greer MJ, Piazuelo MB, Minato N, Olivares-Villagómez D.

PLoS One. 2019 Jul 10;14(7):e0215883. doi: 10.1371/journal.pone.0215883. eCollection 2019.


AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells.

Howard LM, Goll JB, Jensen TL, Hoek KL, Prasad N, Gelber CE, Levy SE, Joyce S, Link AJ, Creech CB, Edwards KM.

J Infect Dis. 2019 May 5;219(11):1786-1798. doi: 10.1093/infdis/jiy721.


Proteomics show antigen presentation processes in human immune cells after AS03-H5N1 vaccination.

Galassie AC, Goll JB, Samir P, Jensen TL, Hoek KL, Howard LM, Allos TM, Niu X, Gordy LE, Creech CB, Hill H, Joyce S, Edwards KM, Link AJ.

Proteomics. 2017 Jun;17(12). doi: 10.1002/pmic.201600453.


Cell-Based Systems Biology Analysis of Human AS03-Adjuvanted H5N1 Avian Influenza Vaccine Responses: A Phase I Randomized Controlled Trial.

Howard LM, Hoek KL, Goll JB, Samir P, Galassie A, Allos TM, Niu X, Gordy LE, Creech CB, Prasad N, Jensen TL, Hill H, Levy SE, Joyce S, Link AJ, Edwards KM.

PLoS One. 2017 Jan 18;12(1):e0167488. doi: 10.1371/journal.pone.0167488. eCollection 2017.


Corrigendum: Distinct Transcriptomic Features Are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen.

Kleiman E, Salyakina D, De Heusch M, Hoek KL, Llanes JM, Castro I, Wright JA, Clark ES, Dykxhoorn DM, Capobianco E, Takeda A, McCormack RM, Podack ER, Renauld JC, Khan WN.

Front Immunol. 2016 Jul 4;7:267. doi: 10.3389/fimmu.2016.00267. eCollection 2016.


Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival.

Rabacal W, Pabbisetty SK, Hoek KL, Cendron D, Guo Y, Maseda D, Sebzda E.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5370-5. doi: 10.1073/pnas.1521491113. Epub 2016 Apr 25.


Distinct Transcriptomic Features are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen.

Kleiman E, Salyakina D, De Heusch M, Hoek KL, Llanes JM, Castro I, Wright JA, Clark ES, Dykxhoorn DM, Capobianco E, Takeda A, Renauld JC, Khan WN.

Front Immunol. 2015 Feb 11;6:30. doi: 10.3389/fimmu.2015.00030. eCollection 2015. Erratum in: Front Immunol. 2016;7:267.


A cell-based systems biology assessment of human blood to monitor immune responses after influenza vaccination.

Hoek KL, Samir P, Howard LM, Niu X, Prasad N, Galassie A, Liu Q, Allos TM, Floyd KA, Guo Y, Shyr Y, Levy SE, Joyce S, Edwards KM, Link AJ.

PLoS One. 2015 Feb 23;10(2):e0118528. doi: 10.1371/journal.pone.0118528. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0122550.


KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production.

Pabbisetty SK, Rabacal W, Maseda D, Cendron D, Collins PL, Hoek KL, Parekh VV, Aune TM, Sebzda E.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9579-84. doi: 10.1073/pnas.1323493111. Epub 2014 Jun 16.


Bruton's tyrosine kinase promotes persistence of mature anti-insulin B cells.

Bonami RH, Sullivan AM, Case JB, Steinberg HE, Hoek KL, Khan WN, Kendall PL.

J Immunol. 2014 Feb 15;192(4):1459-70. doi: 10.4049/jimmunol.1300125. Epub 2014 Jan 22.


A novel algorithm for validating peptide identification from a shotgun proteomics search engine.

Jian L, Niu X, Xia Z, Samir P, Sumanasekera C, Mu Z, Jennings JL, Hoek KL, Allos T, Howard LM, Edwards KM, Weil PA, Link AJ.

J Proteome Res. 2013 Mar 1;12(3):1108-19. doi: 10.1021/pr300631t. Epub 2013 Feb 12.


Follicular B cell trafficking within the spleen actively restricts humoral immune responses.

Hoek KL, Gordy LE, Collins PL, Parekh VV, Aune TM, Joyce S, Thomas JW, Van Kaer L, Sebzda E.

Immunity. 2010 Aug 27;33(2):254-65. doi: 10.1016/j.immuni.2010.07.016. Epub 2010 Aug 5.


Absence of mature peripheral B cell populations in mice with concomitant defects in B cell receptor and BAFF-R signaling.

Hoek KL, Carlesso G, Clark ES, Khan WN.

J Immunol. 2009 Nov 1;183(9):5630-43. doi: 10.4049/jimmunol.0901100.


Reduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgene.

Kendall PL, Moore DJ, Hulbert C, Hoek KL, Khan WN, Thomas JW.

J Immunol. 2009 Nov 15;183(10):6403-12. doi: 10.4049/jimmunol.0900367. Epub 2009 Oct 19.


B cell receptor-mediated sustained c-Rel activation facilitates late transitional B cell survival through control of B cell activating factor receptor and NF-kappaB2.

Castro I, Wright JA, Damdinsuren B, Hoek KL, Carlesso G, Shinners NP, Gerstein RM, Woodland RT, Sen R, Khan WN.

J Immunol. 2009 Jun 15;182(12):7729-37. doi: 10.4049/jimmunol.0803281.


Subunit 1 of the prefoldin chaperone complex is required for lymphocyte development and function.

Cao S, Carlesso G, Osipovich AB, Llanes J, Lin Q, Hoek KL, Khan WN, Ruley HE.

J Immunol. 2008 Jul 1;181(1):476-84.


Bruton's tyrosine kinase mediates NF-kappa B activation and B cell survival by B cell-activating factor receptor of the TNF-R family.

Shinners NP, Carlesso G, Castro I, Hoek KL, Corn RA, Woodland RT, Scott ML, Wang D, Khan WN.

J Immunol. 2007 Sep 15;179(6):3872-80. Erratum in: J Immunol. 2007 Nov 1;179(9):6369. Woodland, Robert L [corrected to Woodland, Robert T].


TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells.

Treml LS, Carlesso G, Hoek KL, Stadanlick JE, Kambayashi T, Bram RJ, Cancro MP, Khan WN.

J Immunol. 2007 Jun 15;178(12):7531-9.


Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement.

Hoek KL, Antony P, Lowe J, Shinners N, Sarmah B, Wente SR, Wang D, Gerstein RM, Khan WN.

J Immunol. 2006 Oct 15;177(8):5405-13.


Low multiplicity of infection of Helicobacter pylori suppresses apoptosis of B lymphocytes.

Bussiere FI, Chaturvedi R, Asim M, Hoek KL, Cheng Y, Gainor J, Scholz A, Khan WN, Wilson KT.

Cancer Res. 2006 Jul 1;66(13):6834-42.


A role for the Mycoplasma pneumoniae adhesin P1 in interleukin (IL)-4 synthesis and release from rodent mast cells.

Hoek KL, Duffy LB, Cassell GH, Dai Y, Atkinson TP.

Microb Pathog. 2005 Oct;39(4):149-58.


Mycoplasma pneumoniae-induced activation and cytokine production in rodent mast cells.

Hoek KL, Cassell GH, Duffy LB, Atkinson TP.

J Allergy Clin Immunol. 2002 Mar;109(3):470-6.


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