Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 74

1.

Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling.

Ryu KY, Lee HJ, Woo H, Kang RJ, Han KM, Park H, Lee SM, Lee JY, Jeong YJ, Nam HW, Nam Y, Hoe HS.

J Neuroinflammation. 2019 Oct 26;16(1):190. doi: 10.1186/s12974-019-1561-x.

2.

ALWPs Improve Cognitive Function and Regulate Aβ Plaque and Tau Hyperphosphorylation in a Mouse Model of Alzheimer's Disease.

Nam Y, Joo B, Lee JY, Han KM, Ryu KY, Koh YH, Kim J, Koo JW, We YM, Hoe HS.

Front Mol Neurosci. 2019 Aug 16;12:192. doi: 10.3389/fnmol.2019.00192. eCollection 2019.

3.

Diverse Structural Conversion and Aggregation Pathways of Alzheimer's Amyloid-β (1-40).

Lin Y, Sahoo BR, Ozawa D, Kinoshita M, Kang J, Lim MH, Okumura M, Huh YH, Moon E, Jang JH, Lee HJ, Ryu KY, Ham S, Won HS, Ryu KS, Sugiki T, Bang JK, Hoe HS, Fujiwara T, Ramamoorthy A, Lee YH.

ACS Nano. 2019 Aug 27;13(8):8766-8783. doi: 10.1021/acsnano.9b01578. Epub 2019 Jul 24.

PMID:
31310506
4.

An Aqueous Extract of Herbal Medicine ALWPs Enhances Cognitive Performance and Inhibits LPS-Induced Neuroinflammation via FAK/NF-κB Signaling Pathways.

Lee JY, Joo B, Nam JH, Nam HY, Lee W, Nam Y, Seo Y, Kang HJ, Cho HJ, Jang YP, Kim J, We YM, Koo JW, Hoe HS.

Front Aging Neurosci. 2018 Sep 26;10:269. doi: 10.3389/fnagi.2018.00269. eCollection 2018.

5.

The small molecule CA140 inhibits the neuroinflammatory response in wild-type mice and a mouse model of AD.

Lee JY, Nam JH, Nam Y, Nam HY, Yoon G, Ko E, Kim SB, Bautista MR, Capule CC, Koyanagi T, Leriche G, Choi HG, Yang J, Kim J, Hoe HS.

J Neuroinflammation. 2018 Oct 11;15(1):286. doi: 10.1186/s12974-018-1321-3.

6.

Ibrutinib suppresses LPS-induced neuroinflammatory responses in BV2 microglial cells and wild-type mice.

Nam HY, Nam JH, Yoon G, Lee JY, Nam Y, Kang HJ, Cho HJ, Kim J, Hoe HS.

J Neuroinflammation. 2018 Sep 19;15(1):271. doi: 10.1186/s12974-018-1308-0.

7.

Synovial Haemangioma of the Elbow: A rare paediatric case and imaging dilemma.

Hoe HG, Zaki FM, Rashid AHA.

Sultan Qaboos Univ Med J. 2018 Feb;18(1):e93-e96. doi: 10.18295/squmj.2018.18.01.015. Epub 2018 Apr 4.

8.

Epimedium koreanum Nakai inhibits PMA-induced cancer cell migration and invasion by modulating NF-κB/MMP-9 signaling in monomorphic malignant human glioma cells.

Lee W, Nam JH, Cho HJ, Lee JY, Cho WK, Kim Υ, We YM, Ma JY, Hoe HS.

Oncol Rep. 2017 Dec;38(6):3619-3631. doi: 10.3892/or.2017.6043. Epub 2017 Oct 17.

PMID:
29130110
9.

Isothiocyanates suppress the invasion and metastasis of tumors by targeting FAK/MMP-9 activity.

Jeong YJ, Cho HJ, Chung FL, Wang X, Hoe HS, Park KK, Kim CH, Chang HW, Lee SR, Chang YC.

Oncotarget. 2017 Jul 12;8(38):63949-63962. doi: 10.18632/oncotarget.19213. eCollection 2017 Sep 8.

10.

Suppression of c-Myc enhances p21WAF1/CIP1 -mediated G1 cell cycle arrest through the modulation of ERK phosphorylation by ascochlorin.

Jeong YJ, Hoe HS, Cho HJ, Park KK, Kim DD, Kim CH, Magae J, Kang DW, Lee SR, Chang YC.

J Cell Biochem. 2018 Feb;119(2):2036-2047. doi: 10.1002/jcb.26366. Epub 2017 Oct 4.

PMID:
28833404
11.

Ascochlorin Suppresses MMP-2-Mediated Migration and Invasion by Targeting FAK and JAK-STAT Signaling Cascades.

Cho HJ, Park JH, Nam JH, Chang YC, Park B, Hoe HS.

J Cell Biochem. 2018 Jan;119(1):300-313. doi: 10.1002/jcb.26179. Epub 2017 Jul 4.

PMID:
28569433
12.

A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Suppresses Cell Migration and Invasion in Monomorphic Malignant Human Glioma Cells by Inhibiting FAK/STAT3 Signaling.

Nam JH, Cho HJ, Kang H, Lee JY, Jung M, Chang YC, Kim K, Hoe HS.

J Cell Biochem. 2017 Dec;118(12):4672-4685. doi: 10.1002/jcb.26133. Epub 2017 Jun 1.

PMID:
28498494
13.

Polo-like kinase 2 phosphorylation of amyloid precursor protein regulates activity-dependent amyloidogenic processing.

Lee Y, Lee JS, Lee KJ, Turner RS, Hoe HS, Pak DTS.

Neuropharmacology. 2017 May 1;117:387-400. doi: 10.1016/j.neuropharm.2017.02.027. Epub 2017 Mar 1.

14.

Delphinidin inhibits angiogenesis through the suppression of HIF-1α and VEGF expression in A549 lung cancer cells.

Kim MH, Jeong YJ, Cho HJ, Hoe HS, Park KK, Park YY, Choi YH, Kim CH, Chang HW, Park YJ, Chung IK, Chang YC.

Oncol Rep. 2017 Feb;37(2):777-784. doi: 10.3892/or.2016.5296. Epub 2016 Dec 7.

PMID:
27959445
15.

A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.

Song JM, Sung YM, Nam JH, Yoon H, Chung A, Moffat E, Jung M, Pak DT, Kim J, Hoe HS.

J Alzheimers Dis. 2016;51(2):591-604. doi: 10.3233/JAD-150717.

PMID:
26890742
16.

Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1-Ras dependent pathway.

Lee NJ, Song JM, Cho HJ, Sung YM, Lee T, Chung A, Hong SH, Cifelli JL, Rubinshtein M, Habib LK, Capule CC, Turner RS, Pak DT, Yang J, Hoe HS.

Biochim Biophys Acta. 2016 Feb;1862(2):284-95. doi: 10.1016/j.bbadis.2015.12.007. Epub 2015 Dec 8.

17.

microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.

Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ramírez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fernández-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J.

J Neurosci. 2015 Nov 4;35(44):14717-26. doi: 10.1523/JNEUROSCI.2053-15.2015.

18.

Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease.

Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK.

J Neurosci. 2015 Aug 12;35(32):11346-57. doi: 10.1523/JNEUROSCI.5289-14.2015.

19.

Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner.

DiBattista AM, Dumanis SB, Song JM, Bu G, Weeber E, Rebeck GW, Hoe HS.

Biochim Biophys Acta. 2015 May;1853(5):904-17. doi: 10.1016/j.bbamcr.2015.01.015. Epub 2015 Jan 31.

20.

Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.

Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G.

Neuron. 2014 Oct 1;84(1):63-77. doi: 10.1016/j.neuron.2014.08.048. Epub 2014 Sep 18.

21.

Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation.

Trotter JH, Lussier AL, Psilos KE, Mahoney HL, Sponaugle AE, Hoe HS, Rebeck GW, Weeber EJ.

Neuroscience. 2014 Aug 22;274:299-307. doi: 10.1016/j.neuroscience.2014.05.046. Epub 2014 Jun 2.

22.

A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease.

Song JM, DiBattista AM, Sung YM, Ahn JM, Turner RS, Yang J, Pak DT, Lee HK, Hoe HS.

Exp Neurol. 2014 Feb;252:105-13. doi: 10.1016/j.expneurol.2013.11.023. Epub 2013 Dec 6.

23.

Antihypertensive drug Valsartan promotes dendritic spine density by altering AMPA receptor trafficking.

Sohn YI, Lee NJ, Chung A, Saavedra JM, Scott Turner R, Pak DT, Hoe HS.

Biochem Biophys Res Commun. 2013 Oct 4;439(4):464-70. doi: 10.1016/j.bbrc.2013.08.091. Epub 2013 Sep 6.

24.

Soluble ICAM-5, a product of activity dependent proteolysis, increases mEPSC frequency and dendritic expression of GluA1.

Lonskaya I, Partridge J, Lalchandani RR, Chung A, Lee T, Vicini S, Hoe HS, Lim ST, Conant K.

PLoS One. 2013 Jul 2;8(7):e69136. doi: 10.1371/journal.pone.0069136. Print 2013.

25.

A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis.

Megill A, Lee T, DiBattista AM, Song JM, Spitzer MH, Rubinshtein M, Habib LK, Capule CC, Mayer M, Turner RS, Kirkwood A, Yang J, Pak DT, Lee HK, Hoe HS.

J Neurosci. 2013 May 29;33(22):9306-18. doi: 10.1523/JNEUROSCI.1615-12.2013. Erratum in: J Neurosci. 2014 Oct 1;34(40):13567.

26.

Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse.

Rogers JT, Zhao L, Trotter JH, Rusiana I, Peters MM, Li Q, Donaldson E, Banko JL, Keenoy KE, Rebeck GW, Hoe HS, D'Arcangelo G, Weeber EJ.

J Psychopharmacol. 2013 Apr;27(4):386-95. doi: 10.1177/0269881112463468. Epub 2012 Oct 26.

27.

Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease.

Sung YM, Lee T, Yoon H, DiBattista AM, Song JM, Sohn Y, Moffat EI, Turner RS, Jung M, Kim J, Hoe HS.

Exp Neurol. 2013 Jan;239:192-201. doi: 10.1016/j.expneurol.2012.10.005. Epub 2012 Oct 11.

28.

FE65 as a link between VLDLR and APP to regulate their trafficking and processing.

Dumanis SB, Chamberlain KA, Jin Sohn Y, Jin Lee Y, Guénette SY, Suzuki T, Mathews PM, Pak DTs, Rebeck GW, Suh YH, Park HS, Hoe HS.

Mol Neurodegener. 2012 Mar 19;7:9. doi: 10.1186/1750-1326-7-9.

29.

MiR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression.

Kim J, Yoon H, Ramírez CM, Lee SM, Hoe HS, Fernández-Hernando C, Kim J.

Exp Neurol. 2012 Jun;235(2):476-83. doi: 10.1016/j.expneurol.2011.11.010. Epub 2011 Nov 18.

30.

Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice.

Babus LW, Little EM, Keenoy KE, Minami SS, Chen E, Song JM, Caviness J, Koo SY, Pak DT, Rebeck GW, Turner RS, Hoe HS.

Brain Res. 2011 Sep 30;1415:96-102. doi: 10.1016/j.brainres.2011.07.059. Epub 2011 Aug 5.

31.

Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density.

Rogers JT, Rusiana I, Trotter J, Zhao L, Donaldson E, Pak DT, Babus LW, Peters M, Banko JL, Chavis P, Rebeck GW, Hoe HS, Weeber EJ.

Learn Mem. 2011 Aug 18;18(9):558-64. doi: 10.1101/lm.2153511. Print 2011 Sep.

32.

Plk2 Raps up Ras to subdue synapses.

Lee KJ, Hoe HS, Pak DT.

Small GTPases. 2011 May;2(3):162-166.

33.

Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice.

Minami SS, Clifford TG, Hoe HS, Matsuoka Y, Rebeck GW.

Neurobiol Aging. 2012 Apr;33(4):825.e15-24. doi: 10.1016/j.neurobiolaging.2011.05.014. Epub 2011 Jul 7.

34.

Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk.

Kim MY, Mo JS, Ann EJ, Yoon JH, Jung J, Choi YH, Kim SM, Kim HY, Ahn JS, Kim H, Kim K, Hoe HS, Park HS.

J Cell Sci. 2011 Jun 1;124(Pt 11):1831-43. doi: 10.1242/jcs.076117. Epub 2011 May 10.

35.

Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes.

Minami SS, Hoe HS, Rebeck GW.

J Neurochem. 2011 Sep;118(5):879-90. doi: 10.1111/j.1471-4159.2011.07296.x. Epub 2011 May 25.

36.

Requirement for Plk2 in orchestrated ras and rap signaling, homeostatic structural plasticity, and memory.

Lee KJ, Lee Y, Rozeboom A, Lee JY, Udagawa N, Hoe HS, Pak DT.

Neuron. 2011 Mar 10;69(5):957-73. doi: 10.1016/j.neuron.2011.02.004.

37.

Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models.

Khandelwal PJ, Herman AM, Hoe HS, Rebeck GW, Moussa CE.

Hum Mol Genet. 2011 Jun 1;20(11):2091-102. doi: 10.1093/hmg/ddr091. Epub 2011 Mar 4.

38.

ApoE receptor 2 regulates synapse and dendritic spine formation.

Dumanis SB, Cha HJ, Song JM, Trotter JH, Spitzer M, Lee JY, Weeber EJ, Turner RS, Pak DT, Rebeck GW, Hoe HS.

PLoS One. 2011 Feb 15;6(2):e17203. doi: 10.1371/journal.pone.0017203.

39.

The upside of APP at synapses.

Hoe HS, Lee HK, Pak DT.

CNS Neurosci Ther. 2012 Jan;18(1):47-56. doi: 10.1111/j.1755-5949.2010.00221.x. Epub 2010 Dec 27. Review.

40.

Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury.

Loane DJ, Washington PM, Vardanian L, Pocivavsek A, Hoe HS, Duff KE, Cernak I, Rebeck GW, Faden AI, Burns MP.

J Neurotrauma. 2011 Feb;28(2):225-36. doi: 10.1089/neu.2010.1595.

41.

Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease.

Minami SS, Sidahmed E, Aid S, Shimoji M, Niikura T, Mocchetti I, Rebeck GW, Prendergast JS, Dealwis C, Wetzel R, Bosetti F, Matsuoka Y, Hoe HS, Turner RS.

J Neuroinflammation. 2010 Sep 28;7:57. doi: 10.1186/1742-2094-7-57.

42.

Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation.

Evers DM, Matta JA, Hoe HS, Zarkowsky D, Lee SH, Isaac JT, Pak DT.

Nat Neurosci. 2010 Oct;13(10):1199-207. doi: 10.1038/nn.2624. Epub 2010 Aug 29.

43.

JIP1 binding to RBP-Jk mediates cross-talk between the Notch1 and JIP1-JNK signaling pathway.

Kim MY, Ann EJ, Mo JS, Dajas-Bailador F, Seo MS, Hong JA, Jung J, Choi YH, Yoon JH, Kim SM, Choi EJ, Hoe HS, Whitmarsh AJ, Park HS.

Cell Death Differ. 2010 Nov;17(11):1728-38. doi: 10.1038/cdd.2010.50. Epub 2010 May 28.

44.

Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines.

Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS.

Neuroscience. 2010 Aug 11;169(1):344-56. doi: 10.1016/j.neuroscience.2010.04.078. Epub 2010 May 6.

45.

ApoE mimetic peptide decreases Abeta production in vitro and in vivo.

Minami SS, Cordova A, Cirrito JR, Tesoriero JA, Babus LW, Davis GC, Dakshanamurthy S, Turner RS, Pak DTs, Rebeck GW, Paige M, Hoe HS.

Mol Neurodegener. 2010 Apr 20;5:16. doi: 10.1186/1750-1326-5-16.

46.

Beta-amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss.

Rebeck GW, Hoe HS, Moussa CE.

J Biol Chem. 2010 Mar 5;285(10):7440-6. doi: 10.1074/jbc.M109.083915. Epub 2010 Jan 13.

47.

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

Dumanis SB, Tesoriero JA, Babus LW, Nguyen MT, Trotter JH, Ladu MJ, Weeber EJ, Turner RS, Xu B, Rebeck GW, Hoe HS.

J Neurosci. 2009 Dec 2;29(48):15317-22. doi: 10.1523/JNEUROSCI.4026-09.2009.

48.

The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement.

Minami SS, Sung YM, Dumanis SB, Chi SH, Burns MP, Ann EJ, Suzuki T, Turner RS, Park HS, Pak DT, Rebeck GW, Hoe HS.

FASEB J. 2010 Jan;24(1):58-69. doi: 10.1096/fj.09-138123. Epub 2009 Aug 31.

49.

Interaction of reelin with amyloid precursor protein promotes neurite outgrowth.

Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW.

J Neurosci. 2009 Jun 10;29(23):7459-73. doi: 10.1523/JNEUROSCI.4872-08.2009.

50.

Combinatorial morphogenesis of dendritic spines and filopodia by SPAR and alpha-actinin2.

Hoe HS, Lee JY, Pak DT.

Biochem Biophys Res Commun. 2009 Jun 19;384(1):55-60. doi: 10.1016/j.bbrc.2009.04.069. Epub 2009 Apr 23.

Supplemental Content

Support Center