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Items: 1 to 50 of 52

1.

The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.

Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.

JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18.

2.

Organoid single cell profiling identifies a transcriptional signature of glomerular disease.

Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, Freedman BS, Kretzler M; European Renal cDNA Bank (ERCB); Nephrotic Syndrome Study Network (NEPTUNE).

JCI Insight. 2019 Jan 10;4(1). pii: 122697. doi: 10.1172/jci.insight.122697. [Epub ahead of print]

3.

Ectonucleotidase-Mediated Suppression of Lupus Autoimmunity and Vascular Dysfunction.

Knight JS, Mazza LF, Yalavarthi S, Sule G, Ali RA, Hodgin JB, Kanthi Y, Pinsky DJ.

Front Immunol. 2018 Jun 11;9:1322. doi: 10.3389/fimmu.2018.01322. eCollection 2018.

4.

TLR7-Mediated Lupus Nephritis Is Independent of Type I IFN Signaling.

Wolf SJ, Theros J, Reed TJ, Liu J, Grigorova IL, Martínez-Colón G, Jacob CO, Hodgin JB, Kahlenberg JM.

J Immunol. 2018 Jul 15;201(2):393-405. doi: 10.4049/jimmunol.1701588. Epub 2018 Jun 8.

5.

Reproducibility and Feasibility of Strategies for Morphologic Assessment of Renal Biopsies Using the Nephrotic Syndrome Study Network Digital Pathology Scoring System.

Zee J, Hodgin JB, Mariani LH, Gaut JP, Palmer MB, Bagnasco SM, Rosenberg AZ, Hewitt SM, Holzman LB, Gillespie BW, Barisoni L.

Arch Pathol Lab Med. 2018 May;142(5):613-625. doi: 10.5858/arpa.2017-0181-OA. Epub 2018 Feb 19.

6.

B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement.

Kim AH, Chung JJ, Akilesh S, Koziell A, Jain S, Hodgin JB, Miller MJ, Stappenbeck TS, Miner JH, Shaw AS.

JCI Insight. 2017 Nov 2;2(21). pii: 81836. doi: 10.1172/jci.insight.81836.

7.

Digital pathology in nephrology clinical trials, research, and pathology practice.

Barisoni L, Hodgin JB.

Curr Opin Nephrol Hypertens. 2017 Nov;26(6):450-459. doi: 10.1097/MNH.0000000000000360. Review.

8.

FSGS as an Adaptive Response to Growth-Induced Podocyte Stress.

Nishizono R, Kikuchi M, Wang SQ, Chowdhury M, Nair V, Hartman J, Fukuda A, Wickman L, Hodgin JB, Bitzer M, Naik A, Wiggins J, Kretzler M, Wiggins RC.

J Am Soc Nephrol. 2017 Oct;28(10):2931-2945. doi: 10.1681/ASN.2017020174. Epub 2017 Jul 18.

9.

Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice.

Zhang H, Nair V, Saha J, Atkins KB, Hodgin JB, Saunders TL, Myers MG Jr, Werner T, Kretzler M, Brosius FC.

Kidney Int. 2017 Oct;92(4):909-921. doi: 10.1016/j.kint.2017.03.027. Epub 2017 May 26.

10.

Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies.

Mariani LH, Martini S, Barisoni L, Canetta PA, Troost JP, Hodgin JB, Palmer M, Rosenberg AZ, Lemley KV, Chien HP, Zee J, Smith A, Appel GB, Trachtman H, Hewitt SM, Kretzler M, Bagnasco SM.

Nephrol Dial Transplant. 2018 Feb 1;33(2):310-318. doi: 10.1093/ndt/gfw443.

11.

An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy.

Kato M, Wang M, Chen Z, Bhatt K, Oh HJ, Lanting L, Deshpande S, Jia Y, Lai JY, O'Connor CL, Wu Y, Hodgin JB, Nelson RG, Bitzer M, Natarajan R.

Nat Commun. 2016 Sep 30;7:12864. doi: 10.1038/ncomms12864.

12.

Psgl-1 Deficiency is Protective against Stroke in a Murine Model of Lupus.

Wang H, Knight JS, Hodgin JB, Wang J, Guo C, Kleiman K, Eitzman DT.

Sci Rep. 2016 Jun 30;6:28997. doi: 10.1038/srep28997.

13.

The Application of Digital Pathology to Improve Accuracy in Glomerular Enumeration in Renal Biopsies.

Rosenberg AZ, Palmer M, Merlino L, Troost JP, Gasim A, Bagnasco S, Avila-Casado C, Johnstone D, Hodgin JB, Conway C, Gillespie BW, Nast CC, Barisoni L, Hewitt SM.

PLoS One. 2016 Jun 16;11(6):e0156441. doi: 10.1371/journal.pone.0156441. eCollection 2016.

14.

Quantitative podocyte parameters predict human native kidney and allograft half-lives.

Naik AS, Afshinnia F, Cibrik D, Hodgin JB, Wu F, Zhang M, Kikuchi M, Wickman L, Samaniego M, Bitzer M, Wiggins JE, Ojo A, Li Y, Wiggins RC.

JCI Insight. 2016;1(7). pii: 86943. doi: 10.1172/jci.insight.86943. Epub 2016 May 19.

15.

Podocyte Depletion in Thin GBM and Alport Syndrome.

Wickman L, Hodgin JB, Wang SQ, Afshinnia F, Kershaw D, Wiggins RC.

PLoS One. 2016 May 18;11(5):e0155255. doi: 10.1371/journal.pone.0155255. eCollection 2016.

16.

Integrative Biology of Diabetic Kidney Disease.

Harder JL, Hodgin JB, Kretzler M.

Kidney Dis (Basel). 2015 Dec;1(3):194-203. doi: 10.1159/000439196. Epub 2015 Sep 23.

17.

Complete Remission in the Nephrotic Syndrome Study Network.

Gipson DS, Troost JP, Lafayette RA, Hladunewich MA, Trachtman H, Gadegbeku CA, Sedor JR, Holzman LB, Moxey-Mims MM, Perumal K, Kaskel FJ, Nelson PJ, Tuttle KR, Bagnasco SM, Hogan MC, Dell KM, Appel GB, Lieske JC, Ilori TO, Sethna CB, Fervenza FC, Hogan SL, Nachman PH, Rosenberg AZ, Greenbaum LA, Meyers KE, Hewitt SM, Choi MJ, Kopp JB, Zhdanova O, Hodgin JB, Johnstone DB, Adler SG, Avila-Casado C, Neu AM, Hingorani SR, Lemley KV, Nast CC, Brady TM, Barisoni-Thomas L, Fornoni A, Jennette JC, Cattran DC, Palmer MB, Gibson KL, Reich HN, Mokrzycki MH, Sambandam KK, Zilleruelo GE, Licht C, Sampson MG, Song P, Mariani LH, Kretzler M.

Clin J Am Soc Nephrol. 2016 Jan 7;11(1):81-9. doi: 10.2215/CJN.02560315. Epub 2015 Dec 10.

18.

Epidermal injury promotes nephritis flare in lupus-prone mice.

Clark KL, Reed TJ, Wolf SJ, Lowe L, Hodgin JB, Kahlenberg JM.

J Autoimmun. 2015 Dec;65:38-48. doi: 10.1016/j.jaut.2015.08.005. Epub 2015 Aug 21.

19.

Morphology in the Digital Age: Integrating High-Resolution Description of Structural Alterations With Phenotypes and Genotypes.

Nast CC, Lemley KV, Hodgin JB, Bagnasco S, Avila-Casado C, Hewitt SM, Barisoni L.

Semin Nephrol. 2015 May;35(3):266-78. doi: 10.1016/j.semnephrol.2015.04.006. Review.

20.

Podometrics as a Potential Clinical Tool for Glomerular Disease Management.

Kikuchi M, Wickman L, Hodgin JB, Wiggins RC.

Semin Nephrol. 2015 May;35(3):245-55. doi: 10.1016/j.semnephrol.2015.04.004. Review.

21.

Glomerular Aging and Focal Global Glomerulosclerosis: A Podometric Perspective.

Hodgin JB, Bitzer M, Wickman L, Afshinnia F, Wang SQ, O'Connor C, Yang Y, Meadowbrooke C, Chowdhury M, Kikuchi M, Wiggins JE, Wiggins RC.

J Am Soc Nephrol. 2015 Dec;26(12):3162-78. doi: 10.1681/ASN.2014080752. Epub 2015 Jun 2.

22.

The two kidney to one kidney transition and transplant glomerulopathy: a podocyte perspective.

Yang Y, Hodgin JB, Afshinnia F, Wang SQ, Wickman L, Chowdhury M, Nishizono R, Kikuchi M, Huang Y, Samaniego M, Wiggins RC.

J Am Soc Nephrol. 2015 Jun;26(6):1450-65. doi: 10.1681/ASN.2014030287. Epub 2014 Nov 11.

23.

The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy.

Hodgin JB, Berthier CC, John R, Grone E, Porubsky S, Gröne HJ, Herzenberg AM, Scholey JW, Hladunewich M, Cattran DC, Kretzler M, Reich HN.

PLoS One. 2014 Aug 18;9(8):e103413. doi: 10.1371/journal.pone.0103413. eCollection 2014.

24.

Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice.

Knight JS, Subramanian V, O'Dell AA, Yalavarthi S, Zhao W, Smith CK, Hodgin JB, Thompson PR, Kaplan MJ.

Ann Rheum Dis. 2015 Dec;74(12):2199-206. doi: 10.1136/annrheumdis-2014-205365. Epub 2014 Aug 7.

25.

Defining nephrotic syndrome from an integrative genomics perspective.

Sampson MG, Hodgin JB, Kretzler M.

Pediatr Nephrol. 2015 Jan;30(1):51-63; quiz 59. doi: 10.1007/s00467-014-2857-9. Epub 2014 Jun 3. Review.

26.

An essential role of caspase 1 in the induction of murine lupus and its associated vascular damage.

Kahlenberg JM, Yalavarthi S, Zhao W, Hodgin JB, Reed TJ, Tsuji NM, Kaplan MJ.

Arthritis Rheumatol. 2014 Jan;66(1):152-62. doi: 10.1002/art.38225.

27.

Fn14 in podocytes and proteinuric kidney disease.

Sanchez-Niño MD, Poveda J, Sanz AB, Mezzano S, Carrasco S, Fernandez-Fernandez B, Burkly LC, Nair V, Kretzler M, Hodgin JB, Ruiz-Ortega M, Selgas R, Egido J, Ortiz A.

Biochim Biophys Acta. 2013 Dec;1832(12):2232-43. doi: 10.1016/j.bbadis.2013.08.010. Epub 2013 Aug 30.

28.

Defining cell-type specificity at the transcriptional level in human disease.

Ju W, Greene CS, Eichinger F, Nair V, Hodgin JB, Bitzer M, Lee YS, Zhu Q, Kehata M, Li M, Jiang S, Rastaldi MP, Cohen CD, Troyanskaya OG, Kretzler M.

Genome Res. 2013 Nov;23(11):1862-73. doi: 10.1101/gr.155697.113. Epub 2013 Aug 15.

29.

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus.

Knight JS, Zhao W, Luo W, Subramanian V, O'Dell AA, Yalavarthi S, Hodgin JB, Eitzman DT, Thompson PR, Kaplan MJ.

J Clin Invest. 2013 Jul;123(7):2981-93. doi: 10.1172/JCI67390. Epub 2013 Jun 3.

30.

Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury.

Blattner SM, Hodgin JB, Nishio M, Wylie SA, Saha J, Soofi AA, Vining C, Randolph A, Herbach N, Wanke R, Atkins KB, Gyung Kang H, Henger A, Brakebusch C, Holzman LB, Kretzler M.

Kidney Int. 2013 Nov;84(5):920-30. doi: 10.1038/ki.2013.175. Epub 2013 May 15.

31.

Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE).

Barisoni L, Nast CC, Jennette JC, Hodgin JB, Herzenberg AM, Lemley KV, Conway CM, Kopp JB, Kretzler M, Lienczewski C, Avila-Casado C, Bagnasco S, Sethi S, Tomaszewski J, Gasim AH, Hewitt SM.

Clin J Am Soc Nephrol. 2013 Aug;8(8):1449-59. doi: 10.2215/CJN.08370812. Epub 2013 Feb 7.

32.

Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli.

Hodgin JB, Nair V, Zhang H, Randolph A, Harris RC, Nelson RG, Weil EJ, Cavalcoli JD, Patel JM, Brosius FC 3rd, Kretzler M.

Diabetes. 2013 Jan;62(1):299-308. doi: 10.2337/db11-1667. Epub 2012 Nov 8.

33.

Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus.

Villanueva E, Yalavarthi S, Berthier CC, Hodgin JB, Khandpur R, Lin AM, Rubin CJ, Zhao W, Olsen SH, Klinker M, Shealy D, Denny MF, Plumas J, Chaperot L, Kretzler M, Bruce AT, Kaplan MJ.

J Immunol. 2011 Jul 1;187(1):538-52. doi: 10.4049/jimmunol.1100450. Epub 2011 May 25.

34.

Experimental approaches to the human renal transcriptome.

Hodgin JB, Cohen CD.

Semin Nephrol. 2010 Sep;30(5):455-67. doi: 10.1016/j.semnephrol.2010.07.003. Review.

PMID:
21044757
35.

A molecular profile of focal segmental glomerulosclerosis from formalin-fixed, paraffin-embedded tissue.

Hodgin JB, Borczuk AC, Nasr SH, Markowitz GS, Nair V, Martini S, Eichinger F, Vining C, Berthier CC, Kretzler M, D'Agati VD.

Am J Pathol. 2010 Oct;177(4):1674-86. doi: 10.2353/ajpath.2010.090746. Epub 2010 Sep 16.

36.

The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.

Zhao W, Thacker SG, Hodgin JB, Zhang H, Wang JH, Park JL, Randolph A, Somers EC, Pennathur S, Kretzler M, Brosius FC 3rd, Kaplan MJ.

J Immunol. 2009 Aug 15;183(4):2729-40. doi: 10.4049/jimmunol.0804341. Epub 2009 Jul 20.

37.

Very low birth weight is a risk factor for secondary focal segmental glomerulosclerosis.

Hodgin JB, Rasoulpour M, Markowitz GS, D'Agati VD.

Clin J Am Soc Nephrol. 2009 Jan;4(1):71-6. doi: 10.2215/CJN.01700408. Epub 2008 Nov 19.

38.

Giant cell tubulitis with immune complex deposits in a patient with lupus nephritis.

Hodgin JB, Whelan J, Markowitz GS, Stokes MB.

Am J Kidney Dis. 2009 Mar;53(3):513-7. doi: 10.1053/j.ajkd.2008.09.015. Epub 2008 Nov 6.

PMID:
18992977
39.

Dent disease presenting as partial Fanconi syndrome and hypercalciuria.

Hodgin JB, Corey HE, Kaplan BS, D'Agati VD.

Kidney Int. 2008 Jun;73(11):1320-3. doi: 10.1038/sj.ki.5002785. Epub 2008 Jan 30. No abstract available.

40.

Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice.

Brosnihan KB, Hodgin JB, Smithies O, Maeda N, Gallagher P.

Exp Physiol. 2008 May;93(5):658-64. doi: 10.1113/expphysiol.2007.041806. Epub 2008 Jan 11.

41.

Asymptomatic intussusception of the appendix secondary to endometriosis.

Offodile A 2nd, Hodgin JB, Arnell T.

Am Surg. 2007 Mar;73(3):299-301.

PMID:
17375794
42.

Minireview: estrogen and mouse models of atherosclerosis.

Hodgin JB, Maeda N.

Endocrinology. 2002 Dec;143(12):4495-501. Review.

PMID:
12446574
43.

The atheroprotective effect of dietary soy isoflavones in apolipoprotein E-/- mice requires the presence of estrogen receptor-alpha.

Adams MR, Golden DL, Register TC, Anthony MS, Hodgin JB, Maeda N, Williams JK.

Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1859-64.

PMID:
12426216
44.

Estrogen-induced osteogenesis in intact female mice lacking ERbeta.

McDougall KE, Perry MJ, Gibson RL, Bright JM, Colley SM, Hodgin JB, Smithies O, Tobias JH.

Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E817-23.

45.

Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice.

Hodgin JB, Knowles JW, Kim HS, Smithies O, Maeda N.

J Clin Invest. 2002 Feb;109(4):541-8.

46.

Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice.

Hodgin JB, Krege JH, Reddick RL, Korach KS, Smithies O, Maeda N.

J Clin Invest. 2001 Feb;107(3):333-40.

47.

Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice.

Karas RH, Hodgin JB, Kwoun M, Krege JH, Aronovitz M, Mackey W, Gustafsson JA, Korach KS, Smithies O, Mendelsohn ME.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15133-6.

48.

Generation and reproductive phenotypes of mice lacking estrogen receptor beta.

Krege JH, Hodgin JB, Couse JF, Enmark E, Warner M, Mahler JF, Sar M, Korach KS, Gustafsson JA, Smithies O.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15677-82.

49.

Male-female differences in fertility and blood pressure in ACE-deficient mice.

Krege JH, John SW, Langenbach LL, Hodgin JB, Hagaman JR, Bachman ES, Jennette JC, O'Brien DA, Smithies O.

Nature. 1995 May 11;375(6527):146-8.

PMID:
7753170
50.

A noninvasive computerized tail-cuff system for measuring blood pressure in mice.

Krege JH, Hodgin JB, Hagaman JR, Smithies O.

Hypertension. 1995 May;25(5):1111-5.

PMID:
7737724

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