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Items: 1 to 50 of 361

1.

De Novo Designed Amphipathic α-Helical Antimicrobial Peptides Incorporating Dab and Dap Residues on the Polar Face To Treat the Gram-Negative Pathogen, Acinetobacter baumannii.

Mant CT, Jiang Z, Gera L, Davis T, Nelson KL, Bevers S, Hodges RS.

J Med Chem. 2019 Apr 11;62(7):3354-3366. doi: 10.1021/acs.jmedchem.8b01785. Epub 2019 Mar 21.

2.

Separation of highly charged (+5 to +10) amphipathic α-helical peptide standards by cation-exchange and reversed-phase high-performance liquid chromatography.

Mant CT, Byars A, Ankarlo S, Jiang Z, Hodges RS.

J Chromatogr A. 2018 Nov 2;1574:60-70. doi: 10.1016/j.chroma.2018.09.003. Epub 2018 Sep 5.

PMID:
30220427
3.

Role of positively charged residues on the polar and non-polar faces of amphipathic α-helical antimicrobial peptides on specificity and selectivity for Gram-negative pathogens.

Jiang Z, Mant CT, Vasil M, Hodges RS.

Chem Biol Drug Des. 2018 Jan;91(1):75-92. doi: 10.1111/cbdd.13058. Epub 2017 Jul 14.

PMID:
28636788
4.

Two Complementary Approaches for the Controlled Release of Biomolecules Immobilized via Coiled-Coil Interactions: Peptide Core Mutations and Multivalent Presentation.

Murschel F, Fortier C, Jolicoeur M, Hodges RS, De Crescenzo G.

Biomacromolecules. 2017 Mar 13;18(3):965-975. doi: 10.1021/acs.biomac.6b01830. Epub 2017 Feb 8.

PMID:
28122454
5.

ProP-ProP and ProP-phospholipid interactions determine the subcellular distribution of osmosensing transporter ProP in Escherichia coli.

Romantsov T, Culham DE, Caplan T, Garner J, Hodges RS, Wood JM.

Mol Microbiol. 2017 Feb;103(3):469-482. doi: 10.1111/mmi.13569. Epub 2016 Nov 25.

6.

Separation of Peptides on HALO 2-Micron Particles.

Mant CT, Hodges RS.

Curr Protoc Protein Sci. 2016 Aug 1;85:11.6.1-11.6.16. doi: 10.1002/cpps.12.

PMID:
27479502
7.

Platform technology to generate broadly cross-reactive antibodies to α-helical epitopes in hemagglutinin proteins from influenza A viruses.

Jiang Z, Gera L, Mant CT, Hirsch B, Yan Z, Shortt JA, Pollock DD, Qian Z, Holmes KV, Hodges RS.

Biopolymers. 2016 Mar;106(2):144-159. doi: 10.1002/bip.22808.

PMID:
26799790
8.

Bradykinin antagonists and thiazolidinone derivatives as new potential anti-cancer compounds.

Avdieiev S, Gera L, Havrylyuk D, Hodges RS, Lesyk R, Ribrag V, Vassetzky Y, Kavsan V.

Bioorg Med Chem. 2014 Aug 1;22(15):3815-23. doi: 10.1016/j.bmc.2014.06.046. Epub 2014 Jun 30.

PMID:
25012567
10.

Functional consequences of AXL sequence variants in hypogonadotropic hypogonadism.

Salian-Mehta S, Xu M, Knox AJ, Plummer L, Slavov D, Taylor M, Bevers S, Hodges RS, Crowley WF Jr, Wierman ME.

J Clin Endocrinol Metab. 2014 Apr;99(4):1452-60. doi: 10.1210/jc.2013-3426. Epub 2014 Jan 29.

11.

Structure-activity relationships of the antimicrobial peptide gramicidin S and its analogs: aqueous solubility, self-association, conformation, antimicrobial activity and interaction with model lipid membranes.

Abraham T, Prenner EJ, Lewis RN, Mant CT, Keller S, Hodges RS, McElhaney RN.

Biochim Biophys Acta. 2014 May;1838(5):1420-9. doi: 10.1016/j.bbamem.2013.12.019. Epub 2014 Jan 2.

13.

Structure-guided RP-HPLC chromatography of diastereomeric α-helical peptide analogs substituted with single amino acid stereoisomers.

Huang Y, Pan L, Zhao L, Mant CT, Hodges RS, Chen Y.

Biomed Chromatogr. 2014 Apr;28(4):511-7. doi: 10.1002/bmc.3061. Epub 2013 Oct 11.

14.

An improved approach to hydrophilic interaction chromatography of peptides: salt gradients in the presence of high isocratic acetonitrile concentrations.

Mant CT, Jiang Z, Boyes BE, Hodges RS.

J Chromatogr A. 2013 Feb 15;1277:15-25. doi: 10.1016/j.chroma.2012.12.044. Epub 2013 Jan 1.

15.

Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver.

Lanaspa MA, Cicerchi C, Garcia G, Li N, Roncal-Jimenez CA, Rivard CJ, Hunter B, Andrés-Hernando A, Ishimoto T, Sánchez-Lozada LG, Thomas J, Hodges RS, Mant CT, Johnson RJ.

PLoS One. 2012;7(11):e48801. doi: 10.1371/journal.pone.0048801. Epub 2012 Nov 9.

16.

Purification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriae.

Zajdowicz S, Haller JC, Krafft AE, Hunsucker SW, Mant CT, Duncan MW, Hodges RS, Jones DN, Holmes RK.

PLoS One. 2012;7(4):e34591. doi: 10.1371/journal.pone.0034591. Epub 2012 Apr 13.

17.

Design of peptide standards with the same composition and minimal sequence variation to monitor performance/selectivity of reversed-phase matrices.

Mant CT, Hodges RS.

J Chromatogr A. 2012 Mar 23;1230:30-40. doi: 10.1016/j.chroma.2012.01.053. Epub 2012 Jan 25.

18.

A D-peptide analog of the second extracellular loop of claudin-3 and -4 leads to mislocalized claudin and cellular apoptosis in mammary epithelial cells.

Baumgartner HK, Beeman N, Hodges RS, Neville MC.

Chem Biol Drug Des. 2011 Feb;77(2):124-36. doi: 10.1111/j.1747-0285.2010.01061.x.

20.

Reversed-phase HPLC of peptides: Assessing column and solvent selectivity on standard, polar-embedded and polar endcapped columns.

Mant CT, Cepeniene D, Hodges RS.

J Sep Sci. 2010 Oct;33(19):3005-21. doi: 10.1002/jssc.201000518.

PMID:
21038458
21.

Anti-tuberculosis activity of α-helical antimicrobial peptides: de novo designed L- and D-enantiomers versus L- and D-LL-37.

Jiang Z, Higgins MP, Whitehurst J, Kisich KO, Voskuil MI, Hodges RS.

Protein Pept Lett. 2011 Mar;18(3):241-52.

22.
23.

Variation of the lateral mobility of transmembrane peptides with hydrophobic mismatch.

Gambin Y, Reffay M, Sierecki E, Homblé F, Hodges RS, Gov NS, Taulier N, Urbach W.

J Phys Chem B. 2010 Mar 18;114(10):3559-66. doi: 10.1021/jp911354y.

PMID:
20170092
24.

Critical interactions in the stability control region of tropomyosin.

Kirwan JP, Hodges RS.

J Struct Biol. 2010 May;170(2):294-306. doi: 10.1016/j.jsb.2010.01.020. Epub 2010 Feb 6.

26.

Identification of a unique "stability control region" that controls protein stability of tropomyosin: A two-stranded alpha-helical coiled-coil.

Hodges RS, Mills J, McReynolds S, Kirwan JP, Tripet B, Osguthorpe D.

J Mol Biol. 2009 Sep 25;392(3):747-62. doi: 10.1016/j.jmb.2009.07.039. Epub 2009 Jul 21.

27.
28.

Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides.

Jiang Z, Vasil AI, Hale J, Hancock RE, Vasil ML, Hodges RS.

Adv Exp Med Biol. 2009;611:561-2. No abstract available.

PMID:
19400313
29.

Expression and characterization of recombinant S2 subunit of SARS-coronavirus S fusion protein.

Yan Z, Holmes KV, Hodges RS.

Adv Exp Med Biol. 2009;611:153-4. No abstract available.

PMID:
19400136
30.

Unique role of clusters of electrostatic attractions in controlling the stability of two-stranded alpha-helical coiled-coils.

Kirwan JP, Kwok SC, McReynolds S, Mills J, Osguthorpe D, Hodges RS.

Adv Exp Med Biol. 2009;611:77-8. No abstract available.

PMID:
19400101
31.

Tracking membrane protein association in model membranes.

Reffay M, Gambin Y, Benabdelhak H, Phan G, Taulier N, Ducruix A, Hodges RS, Urbach W.

PLoS One. 2009;4(4):e5035. doi: 10.1371/journal.pone.0005035. Epub 2009 Apr 1.

32.

Effect of ring size on conformation and biological activity of cyclic cationic antimicrobial peptides.

Jelokhani-Niaraki M, Kondejewski LH, Wheaton LC, Hodges RS.

J Med Chem. 2009 Apr 9;52(7):2090-7. doi: 10.1021/jm801648n.

33.

Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine.

Pimentel TA, Yan Z, Jeffers SA, Holmes KV, Hodges RS, Burkhard P.

Chem Biol Drug Des. 2009 Jan;73(1):53-61. doi: 10.1111/j.1747-0285.2008.00746.x.

34.

Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides.

Jiang Z, Kullberg BJ, van der Lee H, Vasil AI, Hale JD, Mant CT, Hancock RE, Vasil ML, Netea MG, Hodges RS.

Chem Biol Drug Des. 2008 Dec;72(6):483-95. doi: 10.1111/j.1747-0285.2008.00728.x.

35.

Surface nanocrystallization of stainless steel for reduced biofilm adherence.

Yu B, Davis EM, Hodges RS, Irvin RT, Li DY.

Nanotechnology. 2008 Aug 20;19(33):335101. doi: 10.1088/0957-4484/19/33/335101. Epub 2008 Jul 7.

PMID:
21730615
36.

Mixed-mode hydrophilic interaction/cation-exchange chromatography (HILIC/CEX) of peptides and proteins.

Mant CT, Hodges RS.

J Sep Sci. 2008 Aug;31(15):2754-73. doi: 10.1002/jssc.200800243. Review.

37.

Interaction of gramicidin S and its aromatic amino-acid analog with phospholipid membranes.

Jelokhani-Niaraki M, Hodges RS, Meissner JE, Hassenstein UE, Wheaton L.

Biophys J. 2008 Oct;95(7):3306-21. doi: 10.1529/biophysj.108.137471. Epub 2008 Jul 11.

38.

HPLC analysis and purification of peptides.

Mant CT, Chen Y, Yan Z, Popa TV, Kovacs JM, Mills JB, Tripet BP, Hodges RS.

Methods Mol Biol. 2007;386:3-55. doi: 10.1007/978-1-59745-430-8_1.

PMID:
18604941
39.
40.
41.

Core residue replacements cause coiled-coil orientation switching in vitro and in vivo: structure-function correlations for osmosensory transporter ProP.

Tsatskis Y, Kwok SC, Becker E, Gill C, Smith MN, Keates RA, Hodges RS, Wood JM.

Biochemistry. 2008 Jan 8;47(1):60-72. Epub 2007 Dec 13.

PMID:
18076193
42.
43.

The relationship between the binding to and permeabilization of phospholipid bilayer membranes by GS14dK4, a designed analog of the antimicrobial peptide gramicidin S.

Abraham T, Marwaha S, Kobewka DM, Lewis RN, Prenner EJ, Hodges RS, McElhaney RN.

Biochim Biophys Acta. 2007 Sep;1768(9):2089-98. Epub 2007 Jul 6.

45.

Structural and functional analysis of ProQ: an osmoregulatory protein of Escherichia coli.

Smith MN, Kwok SC, Hodges RS, Wood JM.

Biochemistry. 2007 Mar 20;46(11):3084-95. Epub 2007 Feb 24.

PMID:
17319698
46.

Studies of the minimum hydrophobicity of alpha-helical peptides required to maintain a stable transmembrane association with phospholipid bilayer membranes.

Lewis RN, Liu F, Krivanek R, Rybar P, Hianik T, Flach CR, Mendelsohn R, Chen Y, Mant CT, Hodges RS, McElhaney RN.

Biochemistry. 2007 Jan 30;46(4):1042-54.

48.

Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides.

Chen Y, Guarnieri MT, Vasil AI, Vasil ML, Mant CT, Hodges RS.

Antimicrob Agents Chemother. 2007 Apr;51(4):1398-406. Epub 2006 Dec 11.

50.

Dissection of the fusion machine of SARS-coronavirus.

Howard MW, Tripet B, Jobling MG, Holmes RK, Holmes KV, Hodges RS.

Adv Exp Med Biol. 2006;581:319-22. No abstract available.

PMID:
17037552

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