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Neuroethics for the National Institutes of Health BRAIN Initiative.

Bianchi DW, Cooper JA, Gordon JA, Heemskerk J, Hodes R, Koob GF, Koroshetz WJ, Shurtleff D, Sieving PA, Volkow ND, Churchill JD, Ramos KM.

J Neurosci. 2018 Dec 12;38(50):10583-10585. doi: 10.1523/JNEUROSCI.2091-18.2018. No abstract available.


Pharmaceuticals and modern statecraft in South Africa: the cases of opium, thalidomide and contraception.

Parle J, Hodes R, Waetjen T.

Med Humanit. 2018 Dec;44(4):253-262. doi: 10.1136/medhum-2018-011478.


'Yummy or crummy?' The multisensory components of medicines-taking among HIV-positive youth.

Hodes R, Vale B, Toska E, Cluver L, Dowse R, Ashorn M.

Glob Public Health. 2018 Aug 1:1-16. doi: 10.1080/17441692.2018.1504103. [Epub ahead of print]


NIA commentary on the NIA-AA Research Framework: Towards a biological definition of Alzheimer's disease.

Silverberg N, Elliott C, Ryan L, Masliah E, Hodes R.

Alzheimers Dement. 2018 Apr;14(4):576-578. doi: 10.1016/j.jalz.2018.03.004. No abstract available.


Multitype violence exposures and adolescent antiretroviral nonadherence in South Africa.

Cluver L, Meinck F, Toska E, Orkin FM, Hodes R, Sherr L.

AIDS. 2018 May 15;32(8):975-983. doi: 10.1097/QAD.0000000000001795.


The stuff that dreams are made of: HIV-positive adolescents' aspirations for development.

Hodes R, Doubt J, Toska E, Vale B, Zungu N, Cluver L.

J Int AIDS Soc. 2018 Feb;21 Suppl 1. doi: 10.1002/jia2.25057.


Incursions from the epicentre: Southern theory, social science, and the global HIV research domain.

Hodes R, Morrell R.

Afr J AIDS Res. 2018 Mar;17(1):22-31. doi: 10.2989/16085906.2017.1377267. Epub 2018 Feb 22.


Telomere Shortening, Inflammatory Cytokines, and Anti-Cytomegalovirus Antibody Follow Distinct Age-Associated Trajectories in Humans.

Lustig A, Liu HB, Metter EJ, An Y, Swaby MA, Elango P, Ferrucci L, Hodes RJ, Weng NP.

Front Immunol. 2017 Aug 24;8:1027. doi: 10.3389/fimmu.2017.01027. eCollection 2017.


How front-line healthcare workers respond to stock-outs of essential medicines in the Eastern Cape Province of South Africa.

Hodes R, Price I, Bungane N, Toska E, Cluver L.

S Afr Med J. 2017 Aug 25;107(9):738-740. doi: 10.7196/SAMJ.2017.v107i9.12476.


Aging Research: Collaborations Forge a Promising Future.

Kelley MS, Bernard MA, Hodes RJ.

J Am Geriatr Soc. 2017 Nov;65(11):2441-2445. doi: 10.1111/jgs.15052. Epub 2017 Aug 30.


Co-stimulatory function in primary germinal center responses: CD40 and B7 are required on distinct antigen-presenting cells.

Watanabe M, Fujihara C, Radtke AJ, Chiang YJ, Bhatia S, Germain RN, Hodes RJ.

J Exp Med. 2017 Sep 4;214(9):2795-2810. doi: 10.1084/jem.20161955. Epub 2017 Aug 2.


Negotiations of Blame and Care among HIV-positive Mothers and Daughters in South Africa's Eastern Cape.

Vale B, Hodes R, Cluver L.

Med Anthropol Q. 2017 Dec;31(4):519-536. doi: 10.1111/maq.12351. Epub 2017 Mar 12.


Coming of age? Women's sexual and reproductive health after twenty-one years of democracy in South Africa.

Cooper D, Harries J, Moodley J, Constant D, Hodes R, Mathews C, Morroni C, Hoffman M.

Reprod Health Matters. 2016 Nov;24(48):79-89. doi: 10.1016/j.rhm.2016.11.010. Epub 2016 Dec 6.


Disease drivers of aging.

Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, Schafer MJ, LeBrasseur NK, Wiley C, Campisi J, Sehl ME, Scalia R, Eguchi S, Kasinath BS, Halter JB, Cohen HJ, Demark-Wahnefried W, Ahles TA, Barzilai N, Hurria A, Hunt PW.

Ann N Y Acad Sci. 2016 Dec;1386(1):45-68. doi: 10.1111/nyas.13299. Review.


Investigating the Universality of Preoperative Health-Related Quality of Life (HRQoL) for Surgically Treated Spinal Deformity in Young Adults: A Propensity Score-Matched Comparison Between African and US Populations.

Harris BY, Roth MF, Diebo BG, Bess S, Theologis AA, Scheer JK, Schwab FJ, Lafage V, Ames CP, Hodes R, Ayamga J, Boachie-Adjei O; International Spine Study Group.

Spine Deform. 2016 Sep;4(5):351-357. doi: 10.1016/j.jspd.2016.03.006. Epub 2016 Aug 21.


School, Supervision and Adolescent-Sensitive Clinic Care: Combination Social Protection and Reduced Unprotected Sex Among HIV-Positive Adolescents in South Africa.

Toska E, Cluver LD, Boyes ME, Isaacsohn M, Hodes R, Sherr L.

AIDS Behav. 2017 Sep;21(9):2746-2759. doi: 10.1007/s10461-016-1539-y.


T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages.

Chiang YJ, Hodes RJ.

Eur J Immunol. 2016 Oct;46(10):2401-2408. doi: 10.1002/eji.201646440. Epub 2016 Aug 29.


Changing Donor Funding and the Challenges of Integrated HIV Treatment.

Nattrass N, Hodes R, Cluver L.

AMA J Ethics. 2016 Jul 1;18(7):681-90. doi: 10.1001/journalofethics.2016.18.7.ecas3-1607.


Resourcing resilience: social protection for HIV prevention amongst children and adolescents in Eastern and Southern Africa.

Toska E, Gittings L, Hodes R, Cluver LD, Govender K, Chademana KE, Gutiérrez VE.

Afr J AIDS Res. 2016 Jul;15(2):123-40. doi: 10.2989/16085906.2016.1194299. Review. Erratum in: Afr J AIDS Res. 2016 Sep;15(3):314.


Achieving equity in HIV-treatment outcomes: can social protection improve adolescent ART-adherence in South Africa?

Cluver LD, Toska E, Orkin FM, Meinck F, Hodes R, Yakubovich AR, Sherr L.

AIDS Care. 2016 Mar;28 Suppl 2:73-82. doi: 10.1080/09540121.2016.1179008.


Basic science: Bedrock of progress.

Collins FS, Anderson JM, Austin CP, Battey JF, Birnbaum LS, Briggs JP, Clayton JA, Cuthbert B, Eisinger RW, Fauci AS, Gallin JI, Gibbons GH, Glass RI, Gottesman MM, Gray PA, Green ED, Greider FB, Hodes R, Hudson KL, Humphreys B, Katz SI, Koob GF, Koroshetz WJ, Lauer MS, Lorsch JR, Lowy DR, McGowan JJ, Murray DM, Nakamura R, Norris A, Perez-Stable EJ, Pettigrew RI, Riley WT, Rodgers GP, Sieving PA, Somerman MJ, Spong CY, Tabak LA, Volkow ND, Wilder EL.

Science. 2016 Mar 25;351(6280):1405. doi: 10.1126/science.351.6280.1405-a. No abstract available.


Accelerating Medicines Partnership: Alzheimer's Disease (AMP-AD) Knowledge Portal Aids Alzheimer's Drug Discovery through Open Data Sharing.

Hodes RJ, Buckholtz N.

Expert Opin Ther Targets. 2016;20(4):389-91. doi: 10.1517/14728222.2016.1135132. Epub 2016 Feb 7. No abstract available.


Social protection: potential for improving HIV outcomes among adolescents.

Cluver LD, Hodes RJ, Sherr L, Orkin FM, Meinck F, Lim Ah Ken P, Winder-Rossi NE, Wolfe J, Vicari M.

J Int AIDS Soc. 2015 Dec 2;18(Suppl 6):20260. doi: 10.7448/IAS.18.7.20260. eCollection 2015.


Sex and secrecy: How HIV-status disclosure affects safe sex among HIV-positive adolescents.

Toska E, Cluver LD, Hodes R, Kidia KK.

AIDS Care. 2015;27 Suppl 1:47-58. doi: 10.1080/09540121.2015.1071775.


ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans.

Hathcock KS, Padilla-Nash HM, Camps J, Shin DM, Triner D, Shaffer AL 3rd, Maul RW, Steinberg SM, Gearhart PJ, Staudt LM, Morse HC 3rd, Ried T, Hodes RJ.

Blood. 2015 Nov 12;126(20):2291-301. doi: 10.1182/blood-2015-06-654749. Epub 2015 Sep 23.


Apex of deformity for three-column osteotomy. Does it matter in the occurrence of complications?

Sacramento-Domínguez C, Yagi M, Ayamga J, Nemani VM, Akoto H, Mahmud R, Wulff IA, Gupta M, Papadopoulos EC, Pellisé F, Sánchez-Pérez-Grueso F, Hess WF, Kim HJ, Hodes R, Boachie-Adjei O; FOCOS Spine Research Group.

Spine J. 2015 Nov 1;15(11):2351-9. doi: 10.1016/j.spinee.2015.07.010. Epub 2015 Jul 10.


'HIV is like a tsotsi. ARVs are your guns': associations between HIV-disclosure and adherence to antiretroviral treatment among adolescents in South Africa.

Cluver LD, Hodes RJ, Toska E, Kidia KK, Orkin FM, Sherr L, Meinck F.

AIDS. 2015 Jun;29 Suppl 1:S57-65. doi: 10.1097/QAD.0000000000000695.


Preoperative halo-gravity traction for severe spinal deformities at an SRS-GOP site in West Africa: protocols, complications, and results.

Nemani VM, Kim HJ, Bjerke-Kroll BT, Yagi M, Sacramento-Dominguez C, Akoto H, Papadopoulos EC, Sanchez-Perez-Grueso F, Pellise F, Nguyen JT, Wulff I, Ayamga J, Mahmud R, Hodes RM, Boachie-Adjei O; FOCOS Spine Study Group.

Spine (Phila Pa 1976). 2015 Feb 1;40(3):153-61. doi: 10.1097/BRS.0000000000000675.


Regulation of T cell development by c-Cbl: essential role of Lck.

Chiang YJ, Hodes RJ.

Int Immunol. 2015 May;27(5):245-51. doi: 10.1093/intimm/dxu105. Epub 2014 Dec 4.


T cell-B cell thymic cross-talk: maintenance and function of thymic B cells requires cognate CD40-CD40 ligand interaction.

Fujihara C, Williams JA, Watanabe M, Jeon H, Sharrow SO, Hodes RJ.

J Immunol. 2014 Dec 1;193(11):5534-44. doi: 10.4049/jimmunol.1401655. Epub 2014 Oct 24.


Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions.

Lin Y, Damjanovic A, Metter EJ, Nguyen H, Truong T, Najarro K, Morris C, Longo DL, Zhan M, Ferrucci L, Hodes RJ, Weng NP.

Clin Sci (Lond). 2015 Mar;128(6):367-77. doi: 10.1042/CS20140481.


Downmodulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4(+) T cell responses.

Watanabe M, Moon KD, Vacchio MS, Hathcock KS, Hodes RJ.

Immunity. 2014 May 15;40(5):681-91. doi: 10.1016/j.immuni.2014.04.006. Epub 2014 May 1.


Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.

Williams JA, Zhang J, Jeon H, Nitta T, Ohigashi I, Klug D, Kruhlak MJ, Choudhury B, Sharrow SO, Granger L, Adams A, Eckhaus MA, Jenkinson SR, Richie ER, Gress RE, Takahama Y, Hodes RJ.

J Immunol. 2014 Jan 15;192(2):630-40. doi: 10.4049/jimmunol.1302550. Epub 2013 Dec 13.


TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.

Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, Takahama Y, Hodes RJ.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21107-12. doi: 10.1073/pnas.1314859111. Epub 2013 Dec 9.


A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restriction.

Bowen S, Sun P, Livak F, Sharrow S, Hodes RJ.

J Immunol. 2014 Jan 1;192(1):169-77. doi: 10.4049/jimmunol.1302398. Epub 2013 Dec 4.


ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire.

Hathcock KS, Bowen S, Livak F, Hodes RJ.

PLoS One. 2013 Apr 23;8(4):e62188. doi: 10.1371/journal.pone.0062188. Print 2013.


The NIH toolbox: setting a standard for biomedical research.

Hodes RJ, Insel TR, Landis SC; NIH Blueprint for Neuroscience Research.

Neurology. 2013 Mar 12;80(11 Suppl 3):S1. doi: 10.1212/WNL.0b013e3182872e90.


Fecal flora reconstitution for amyotrophic lateral sclerosis.

Hodes RM.

J Clin Gastroenterol. 2013 Aug;47(7):655. doi: 10.1097/MCG.0b013e3182897a14. No abstract available.


Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes.

Bowen S, Wangsa D, Ried T, Livak F, Hodes RJ.

Nucleic Acids Res. 2013 Apr;41(8):4535-48. doi: 10.1093/nar/gkt154. Epub 2013 Mar 6.


Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.

Lucas CR, Cordero-Nieves HM, Erbe RS, McAlees JW, Bhatia S, Hodes RJ, Campbell KS, Sanders VM.

J Immunol. 2013 Jan 15;190(2):723-36. doi: 10.4049/jimmunol.1201646. Epub 2012 Dec 12.


Exon 1 disruption alters tissue-specific expression of mouse p53 and results in selective development of B cell lymphomas.

Chiang YJ, Difilippantonio MJ, Tessarollo L, Morse HC, Hodes RJ.

PLoS One. 2012;7(11):e49305. doi: 10.1371/journal.pone.0049305. Epub 2012 Nov 14.


Editorial overview.

Akbar AN, Hodes RJ.

Curr Opin Immunol. 2012 Aug;24(4):467-9. doi: 10.1016/j.coi.2012.07.002. Epub 2012 Jul 23. No abstract available.


From comprehensive medicine to public health at the University of Cape Town: a 40-year journey.

Hoffman M, Coetzee D, Hodes R, London L.

S Afr Med J. 2012 Mar 23;102(6):442-5.


National Institute on Aging at middle age--its past, present, and future.

Nagy CL, Bernard MA, Hodes RJ.

J Am Geriatr Soc. 2012 Jun;60(6):1165-9. doi: 10.1111/j.1532-5415.2012.03994.x. Epub 2012 May 30.


Piloting antiretroviral treatment in South Africa: the role of partnerships in the Western Cape's provincial roll-out.

Hodes R, Naimak TH.

Afr J AIDS Res. 2011 Dec;10(4):415-25. doi: 10.2989/16085906.2011.646656.


Epidemiology, comparative effectiveness research, and the National Institutes of Health: forces for health.

Lauer MS, Hodes R.

Epidemiology. 2011 Sep;22(5):625-8. doi: 10.1097/EDE.0b013e3182262ac6. No abstract available.


The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.

Hathcock KS, Farrington L, Ivanova I, Livak F, Selimyan R, Sen R, Williams J, Tai X, Hodes RJ.

PLoS One. 2011;6(6):e20639. doi: 10.1371/journal.pone.0020639. Epub 2011 Jun 3.


Cbl enforces Vav1 dependence and a restricted pathway of T cell development.

Chiang J, Hodes RJ.

PLoS One. 2011 Apr 7;6(4):e18542. doi: 10.1371/journal.pone.0018542.


Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.

Lu J, Chiang J, Iyer RR, Thompson E, Kaneski CR, Xu DS, Yang C, Chen M, Hodes RJ, Lonser RR, Brady RO, Zhuang Z.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21665-70. doi: 10.1073/pnas.1014376107. Epub 2010 Nov 22.

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