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Items: 30


Analysis of Lipid Metabolism, Immune Function, and Neurobehavior in Adult C57BL/6JxFVB Mice After Developmental Exposure to di (2-ethylhexyl) Phthalate.

Bastos Sales L, van Esterik JCJ, Hodemaekers HM, Lamoree MH, Hamers T, van der Ven LTM, Legler J.

Front Endocrinol (Lausanne). 2018 Nov 21;9:684. doi: 10.3389/fendo.2018.00684. eCollection 2018.


Transcriptomics in lung tissue upon respiratory syncytial virus infection reveals aging as important modulator of immune activation and matrix maintenance.

Pennings JLA, Mariman R, Hodemaekers HM, Reemers SSN, Janssen R, Guichelaar T.

Sci Rep. 2018 Nov 9;8(1):16653. doi: 10.1038/s41598-018-35180-2.


A high crosslinking grade of hyaluronic acid found in a dermal filler causing adverse effects.

Keizers PHJ, Vanhee C, van den Elzen EMW, de Jong WH, Venhuis BJ, Hodemaekers HM, Schwillens P, Lensen DGW.

J Pharm Biomed Anal. 2018 Sep 10;159:173-178. doi: 10.1016/j.jpba.2018.06.066. Epub 2018 Jul 2.


Programmed Effects in Neurobehavior and Antioxidative Physiology in Zebrafish Embryonically Exposed to Cadmium: Observations and Hypothesized Adverse Outcome Pathway Framework.

Ruiter S, Sippel J, Bouwmeester MC, Lommelaars T, Beekhof P, Hodemaekers HM, Bakker F, van den Brandhof EJ, Pennings JL, van der Ven LT.

Int J Mol Sci. 2016 Nov 2;17(11). pii: E1830.


Functional and genetic predisposition to rhinovirus lower respiratory tract infections in prematurely born infants.

Drysdale SB, Alcazar M, Wilson T, Smith M, Zuckerman M, Hodemaekers HM, Janssen R, Bont L, Johnston SL, Greenough A.

Eur J Pediatr. 2016 Dec;175(12):1943-1949. Epub 2016 Oct 1.


Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis.

Han WG, Hodemaekers HM, Nagarajah B, Poelen MM, Helm K, Janssen R, van Els CA.

PLoS One. 2016 Feb 19;11(2):e0149576. doi: 10.1371/journal.pone.0149576. eCollection 2016.


Zebrafish embryos as a screen for DNA methylation modifications after compound exposure.

Bouwmeester MC, Ruiter S, Lommelaars T, Sippel J, Hodemaekers HM, van den Brandhof EJ, Pennings JL, Kamstra JH, Jelinek J, Issa JP, Legler J, van der Ven LT.

Toxicol Appl Pharmacol. 2016 Jan 15;291:84-96. doi: 10.1016/j.taap.2015.12.012. Epub 2015 Dec 19.


Interleukin-15 is associated with disease severity in viral bronchiolitis.

Leahy TR, McManus R, Doherty DG, Grealy R, Coulter T, Smyth P, Blackshields G, Sheils O, Carr MJ, Purandare N, Geary M, Hodemaekers HM, Janssen R, Bont L, Slattery D, Ryan T.

Eur Respir J. 2016 Jan;47(1):212-22. doi: 10.1183/13993003.00642-2015. Epub 2015 Nov 5.


Compound- and sex-specific effects on programming of energy and immune homeostasis in adult C57BL/6JxFVB mice after perinatal TCDD and PCB 153.

van Esterik JC, Verharen HW, Hodemaekers HM, Gremmer ER, Nagarajah B, Kamstra JH, Dollé ME, Legler J, van der Ven LT.

Toxicol Appl Pharmacol. 2015 Dec 1;289(2):262-75. doi: 10.1016/j.taap.2015.09.017. Epub 2015 Sep 28.


Dysregulation of serum gamma interferon levels in vascular chronic Q Fever patients provides insights into disease pathogenesis.

Pennings JL, Kremers MN, Hodemaekers HM, Hagenaars JC, Koning OH, Renders NH, Hermans MH, de Klerk A, Notermans DW, Wever PC, Janssen R.

Clin Vaccine Immunol. 2015 Jun;22(6):664-71. doi: 10.1128/CVI.00078-15. Epub 2015 Apr 29.


Single nucleotide polymorphisms in immune response genes in acute Q fever cases with differences in self-reported symptoms.

Wielders CC, Hackert VH, Schimmer B, Hodemaekers HM, de Klerk A, Hoebe CJ, Schneeberger PM, van Duynhoven YT, Janssen R.

Eur J Clin Microbiol Infect Dis. 2015 May;34(5):943-50. doi: 10.1007/s10096-014-2310-9. Epub 2015 Jan 11.


Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A.

van Esterik JC, Vitins AP, Hodemaekers HM, Kamstra JH, Legler J, Pennings JL, Steegenga WT, Lute C, Jelinek J, Issa JP, Dollé ME, van der Ven LT.

Toxicol Lett. 2015 Jan 5;232(1):293-300. doi: 10.1016/j.toxlet.2014.10.021. Epub 2014 Oct 17.


Genetic predisposition of RSV infection-related respiratory morbidity in preterm infants.

Drysdale SB, Prendergast M, Alcazar M, Wilson T, Smith M, Zuckerman M, Broughton S, Rafferty GF, Johnston SL, Hodemaekers HM, Janssen R, Bont L, Greenough A.

Eur J Pediatr. 2014 Jul;173(7):905-12. doi: 10.1007/s00431-014-2263-0. Epub 2014 Feb 2.


Correlations between peripheral blood Coxiella burnetii DNA load, interleukin-6 levels, and C-reactive protein levels in patients with acute Q fever.

Kremers MN, Janssen R, Wielders CC, Kampschreur LM, Schneeberger PM, Netten PM, de Klerk A, Hodemaekers HM, Hermans MH, Notermans DW, Wever PC.

Clin Vaccine Immunol. 2014 Apr;21(4):484-7. doi: 10.1128/CVI.00715-13. Epub 2014 Jan 29.


Opioid receptors control viral replication in the airways.

Salimi V, Hennus MP, Mokhtari-Azad T, Shokri F, Janssen R, Hodemaekers HM, Rygiel TP, Coenjaerts FE, Meyaard L, Bont L.

Crit Care Med. 2013 Jan;41(1):205-14. doi: 10.1097/CCM.0b013e31826767a8.


Host response to mechanical ventilation for viral respiratory tract infection.

Hennus MP, Janssen R, Pennings JL, Hodemaekers HM, Kruijsen D, Jansen NJ, Meyaard L, van Vught AJ, Bont LJ.

Eur Respir J. 2012 Dec;40(6):1508-15. doi: 10.1183/09031936.00177111. Epub 2012 Apr 10.


Development and comparison of two assay formats for parallel detection of four biothreat pathogens by using suspension microarrays.

Janse I, Bok JM, Hamidjaja RA, Hodemaekers HM, van Rotterdam BJ.

PLoS One. 2012;7(2):e31958. doi: 10.1371/journal.pone.0031958. Epub 2012 Feb 15.


Proteins involved in extracellular matrix dynamics are associated with respiratory syncytial virus disease severity.

Schuurhof A, Bont L, Hodemaekers HM, de Klerk A, de Groot H, Hofland RW, van de Pol AC, Kimpen JL, Janssen R.

Eur Respir J. 2012 Jun;39(6):1475-81. doi: 10.1183/09031936.00012311. Epub 2012 Jan 20.


Local interleukin-10 production during respiratory syncytial virus bronchiolitis is associated with post-bronchiolitis wheeze.

Schuurhof A, Janssen R, de Groot H, Hodemaekers HM, de Klerk A, Kimpen JL, Bont L.

Respir Res. 2011 Sep 12;12:121. doi: 10.1186/1465-9921-12-121.


IL10 family member genes IL19 and IL20 are associated with recurrent wheeze after respiratory syncytial virus bronchiolitis.

Ermers MJ, Janssen R, Onland-Moret NC, Hodemaekers HM, Rovers MM, Houben ML, Kimpen JL, Bont LJ.

Pediatr Res. 2011 Nov;70(5):518-23. doi: 10.1203/PDR.0b013e31822f5863.


Systemic signature of the lung response to respiratory syncytial virus infection.

Pennings JL, Schuurhof A, Hodemaekers HM, Buisman A, de Rond LC, Widjojoatmodjo MN, Luytjes W, Kimpen JL, Bont L, Janssen R.

PLoS One. 2011;6(6):e21461. doi: 10.1371/journal.pone.0021461. Epub 2011 Jun 24.


Gene expression profiles induced by Salmonella infection in resistant and susceptible mice.

Cawthraw S, Pennings JL, Hodemaekers HM, de Jonge R, Havelaar AH, Hoebee B, Johnson L, Best A, Kennedy E, La Ragione RM, Newell DG, Janssen R.

Microbes Infect. 2011 Apr;13(4):383-93. doi: 10.1016/j.micinf.2011.01.001. Epub 2011 Jan 20.


Gene expression differences in lungs of mice during secondary immune responses to respiratory syncytial virus infection.

Schuurhof A, Bont L, Pennings JL, Hodemaekers HM, Wester PW, Buisman A, de Rond LC, Widjojoatmodjo MN, Luytjes W, Kimpen JL, Janssen R.

J Virol. 2010 Sep;84(18):9584-94. doi: 10.1128/JVI.00302-10. Epub 2010 Jun 30.


Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.

Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R.

Pediatr Infect Dis J. 2009 Apr;28(4):333-5. doi: 10.1097/INF.0b013e31818e2aa9.


Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.

Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, van 't Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B.

J Infect Dis. 2007 Sep 15;196(6):826-34. Epub 2007 Aug 10.


IL-13 genetic polymorphism identifies children with late wheezing after respiratory syncytial virus infection.

Ermers MJ, Hoebee B, Hodemaekers HM, Kimman TG, Kimpen JL, Bont L.

J Allergy Clin Immunol. 2007 May;119(5):1086-91. Epub 2007 Feb 20.


Influence of promoter variants of interleukin-10, interleukin-9, and tumor necrosis factor-alpha genes on respiratory syncytial virus bronchiolitis.

Hoebee B, Bont L, Rietveld E, van Oosten M, Hodemaekers HM, Nagelkerke NJ, Neijens HJ, Kimpen JL, Kimman TG.

J Infect Dis. 2004 Jan 15;189(2):239-47. Epub 2004 Jan 9.


Association of severe respiratory syncytial virus bronchiolitis with interleukin-4 and interleukin-4 receptor alpha polymorphisms.

Hoebee B, Rietveld E, Bont L, Oosten Mv, Hodemaekers HM, Nagelkerke NJ, Neijens HJ, Kimpen JL, Kimman TG.

J Infect Dis. 2003 Jan 1;187(1):2-11. Epub 2002 Dec 13.


The translation in vitro of rat ornithine decarboxylase mRNA is blocked by its 5' untranslated region in a polyamine-independent way.

Van Steeg H, Van Oostrom CT, Hodemaekers HM, Peters L, Thomas AA.

Biochem J. 1991 Mar 1;274 ( Pt 2):521-6.


Cloning and functional analysis of the rat ornithine decarboxylase-encoding gene.

van Steeg H, van Oostrom CT, Hodemaekers HM, van Kreyl CF.

Gene. 1990 Sep 14;93(2):249-56.


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