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Items: 23


Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study).

Waitt C, Orrell C, Walimbwa S, Singh Y, Kintu K, Simmons B, Kaboggoza J, Sihlangu M, Coombs JA, Malaba T, Byamugisha J, Amara A, Gini J, Else L, Heiburg C, Hodel EM, Reynolds H, Mehta U, Byakika-Kibwika P, Hill A, Myer L, Lamorde M, Khoo S.

PLoS Med. 2019 Sep 20;16(9):e1002895. doi: 10.1371/journal.pmed.1002895. eCollection 2019 Sep.


Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp.

Jones S, Kay K, Hodel EM, Chy S, Mbituyumuremyi A, Uwimana A, Menard D, Felger I, Hastings I.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e00590-19. doi: 10.1128/AAC.00590-19. Print 2019 Sep.


Pharmacokinetics, Placental and Breast Milk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV.

Hodel EM, Marzolini C, Waitt C, Rakhmanina N.

Curr Pharm Des. 2019;25(5):556-576. doi: 10.2174/1381612825666190320162507.


Optimal Treatments for Severe Malaria and the Threat Posed by Artemisinin Resistance.

Jones S, Hodel EM, Sharma R, Kay K, Hastings IM.

J Infect Dis. 2019 Apr 8;219(8):1243-1253. doi: 10.1093/infdis/jiy649.


Comparison of Two Genotyping Methods for Distinguishing Recrudescence from Reinfection in Antimalarial Drug Efficacy/Effectiveness Trials.

Fulakeza JRM, Banda RL, Lipenga TR, Terlouw DJ, Nkhoma SC, Hodel EM.

Am J Trop Med Hyg. 2018 Jul;99(1):84-86. doi: 10.4269/ajtmh.18-0002. Epub 2018 May 17.


Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation.

Millard J, Pertinez H, Bonnett L, Hodel EM, Dartois V, Johnson JL, Caws M, Tiberi S, Bolhuis M, Alffenaar JC, Davies G, Sloan DJ.

J Antimicrob Chemother. 2018 Jul 1;73(7):1755-1762. doi: 10.1093/jac/dky096.


Stability of Dihydroartemisinin-Piperaquine Tablet Halves During Prolonged Storage Under Tropical Conditions.

Hodel EM, Kaur H, Terlouw DJ.

Am J Trop Med Hyg. 2017 Feb 8;96(2):338-340. doi: 10.4269/ajtmh.16-0759. Epub 2016 Nov 28.


Quantifying the pharmacology of antimalarial drug combination therapy.

Hastings IM, Hodel EM, Kay K.

Sci Rep. 2016 Sep 8;6:32762. doi: 10.1038/srep32762.


The Importance of Scientific Debate in the Identification, Containment, and Control of Artemisinin Resistance.

Hastings IM, Kay K, Hodel EM.

Clin Infect Dis. 2016 Dec 1;63(11):1527-1528. Epub 2016 Aug 23. No abstract available.


Incorporating Stage-Specific Drug Action into Pharmacological Modeling of Antimalarial Drug Treatment.

Hodel EM, Kay K, Hastings IM.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2747-56. doi: 10.1128/AAC.01172-15. Print 2016 May.


Reply to "Parasite Strain, Host Immunity, and Circulating Blood Cells with Dead Parasites: Why Predicting Malaria Parasite Clearance Is Not a Simple Task".

Hastings IM, Kay K, Hodel EM.

Antimicrob Agents Chemother. 2016 Jan 29;60(2):1173-4. doi: 10.1128/AAC.02570-15. Print 2016 Feb. No abstract available.


Cochrane Column.

Wiysonge CS, Wiysonge CS, Zani B, Mbacham W, Hodel EM, Terlouw DJ.

Int J Epidemiol. 2015 Oct;44(5):1502-5. doi: 10.1093/ije/dyv163. Epub 2015 Aug 29. No abstract available.


Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness.

Kay K, Hodel EM, Hastings IM.

Antimicrob Agents Chemother. 2015 Oct;59(10):6419-27. doi: 10.1128/AAC.00482-15. Epub 2015 Aug 3.


How Robust Are Malaria Parasite Clearance Rates as Indicators of Drug Effectiveness and Resistance?

Hastings IM, Kay K, Hodel EM.

Antimicrob Agents Chemother. 2015 Oct;59(10):6428-36. doi: 10.1128/AAC.00481-15. Epub 2015 Aug 3.


Age-shifting in malaria incidence as a result of induced immunological deficit: a simulation study.

Pemberton-Ross P, Smith TA, Hodel EM, Kay K, Penny MA.

Malar J. 2015 Jul 25;14:287. doi: 10.1186/s12936-015-0805-1.


Improving the role and contribution of pharmacokinetic analyses in antimalarial drug clinical trials.

Kay K, Hodel EM, Hastings IM.

Antimicrob Agents Chemother. 2014 Oct;58(10):5643-9. doi: 10.1128/AAC.02777-14. Epub 2014 Jun 30.


Optimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling.

Hodel EM, Kay K, Hayes DJ, Terlouw DJ, Hastings IM.

Malar J. 2014 Apr 7;13:138. doi: 10.1186/1475-2875-13-138.


Pharmacological considerations in the design of anti-malarial drug combination therapies - is matching half-lives enough?

Hastings IM, Hodel EM.

Malar J. 2014 Feb 20;13:62. doi: 10.1186/1475-2875-13-62. Review.


Residual antimalarial concentrations before treatment in patients with malaria from Cambodia: indication of drug pressure.

Hodel EM, Genton B, Zanolari B, Mercier T, Duong S, Beck HP, Olliaro P, Decosterd LA, Ariey F.

J Infect Dis. 2010 Oct 1;202(7):1088-94. doi: 10.1086/655779.


Residual antimalarials in malaria patients from Tanzania--implications on drug efficacy assessment and spread of parasite resistance.

Hodel EM, Kabanywanyi AM, Malila A, Zanolari B, Mercier T, Beck HP, Buclin T, Olliaro P, Decosterd LA, Genton B.

PLoS One. 2009 Dec 14;4(12):e8184. doi: 10.1371/journal.pone.0008184.


A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma.

Hodel EM, Zanolari B, Mercier T, Biollaz J, Keiser J, Olliaro P, Genton B, Decosterd LA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Apr 1;877(10):867-86. doi: 10.1016/j.jchromb.2009.02.006. Epub 2009 Feb 11.


Lack of multiple copies of pfmdr1 gene in Papua New Guinea.

Hodel EM, Marfurt J, Müller D, Rippert A, Borrmann S, Müller I, Reeder JC, Siba P, Genton B, Beck HP.

Trans R Soc Trop Med Hyg. 2008 Nov;102(11):1151-3. doi: 10.1016/j.trstmh.2008.05.017. Epub 2008 Jul 2.


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