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Items: 1 to 50 of 80

1.

Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans.

Lampe JW, Kim E, Levy L, Davidson LA, Goldsby JS, Miles FL, Navarro SL, Randolph TW, Zhao N, Ivanov I, Kaz AM, Damman C, Hockenbery DM, Hullar MAJ, Chapkin RS.

Am J Clin Nutr. 2019 Aug 1;110(2):377-390. doi: 10.1093/ajcn/nqy325.

PMID:
31175806
2.

Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.

Centini R, Tsang M, Iwata T, Park H, Delrow J, Margineantu D, Iritani BM, Gu H, Liggitt HD, Kang J, Kang L, Hockenbery DM, Raftery D, Iritani BM.

PLoS One. 2018 Jun 13;13(6):e0197973. doi: 10.1371/journal.pone.0197973. eCollection 2018.

3.

A Metabolomics Study of BPTES Altered Metabolism in Human Breast Cancer Cell Lines.

Nagana Gowda GA, Barding GA Jr, Dai J, Gu H, Margineantu DH, Hockenbery DM, Raftery D.

Front Mol Biosci. 2018 May 15;5:49. doi: 10.3389/fmolb.2018.00049. eCollection 2018.

4.

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.

Davis RJ, Gönen M, Margineantu DH, Handeli S, Swanger J, Hoellerbauer P, Paddison PJ, Gu H, Raftery D, Grim JE, Hockenbery DM, Margolin AA, Clurman BE.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):5462-5467. doi: 10.1073/pnas.1718338115. Epub 2018 May 7.

5.

Inhibition of vaccinia virus replication by nitazoxanide.

Hickson SE, Margineantu D, Hockenbery DM, Simon JA, Geballe AP.

Virology. 2018 May;518:398-405. doi: 10.1016/j.virol.2018.03.023. Epub 2018 Apr 3.

6.

Pathological assessment of gastrointestinal biopsies from patients with idelalisib-associated diarrhea and colitis.

Yeung CC, Hockenbery DM, Westerhoff M, Coutre SE, Sedlak RH, Dubowy RL, Munugalavadla V, Taylor K, Bosch F.

Future Oncol. 2018 Sep;14(22):2265-2277. doi: 10.2217/fon-2017-0528. Epub 2018 Mar 23.

7.

Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease.

Steinbach G, Hockenbery DM, Huls G, Furlong T, Myerson D, Loeb KR, Fann JR, Castilla-Llorente C, McDonald GB, Martin PJ.

PLoS One. 2017 Aug 17;12(8):e0183284. doi: 10.1371/journal.pone.0183284. eCollection 2017.

8.

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.

Berger S, Procko E, Margineantu D, Lee EF, Shen BW, Zelter A, Silva DA, Chawla K, Herold MJ, Garnier JM, Johnson R, MacCoss MJ, Lessene G, Davis TN, Stayton PS, Stoddard BL, Fairlie WD, Hockenbery DM, Baker D.

Elife. 2016 Nov 2;5. pii: e20352. doi: 10.7554/eLife.20352.

9.

Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.

Iwata TN, Ramírez JA, Tsang M, Park H, Margineantu DH, Hockenbery DM, Iritani BM.

J Immunol. 2016 Sep 15;197(6):2250-60. doi: 10.4049/jimmunol.1600492. Epub 2016 Aug 12.

10.

Mitochondrial functions in stem cells.

Margineantu DH, Hockenbery DM.

Curr Opin Genet Dev. 2016 Jun;38:110-117. doi: 10.1016/j.gde.2016.05.004. Epub 2016 Jun 5. Review.

PMID:
27269732
11.

Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy.

Reyes NL, Banks GB, Tsang M, Margineantu D, Gu H, Djukovic D, Chan J, Torres M, Liggitt HD, Hirenallur-S DK, Hockenbery DM, Raftery D, Iritani BM.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):424-9. doi: 10.1073/pnas.1413021112. Epub 2014 Dec 29.

12.

Fibrosing cholestatic hepatitis C after hematopoietic cell transplantation: report of 3 fatal cases.

Evans AT, Loeb KR, Shulman HM, Hassan S, Qiu WC, Hockenbery DM, Ioannou GN, Chauncey TR, Gretch DR, McDonald GB.

Am J Surg Pathol. 2015 Feb;39(2):212-20. doi: 10.1097/PAS.0000000000000345.

PMID:
25517948
13.

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells.

Procko E, Berguig GY, Shen BW, Song Y, Frayo S, Convertine AJ, Margineantu D, Booth G, Correia BE, Cheng Y, Schief WR, Hockenbery DM, Press OW, Stoddard BL, Stayton PS, Baker D.

Cell. 2014 Jun 19;157(7):1644-1656. doi: 10.1016/j.cell.2014.04.034.

14.

Forecast: rough seas for leukemia.

Hockenbery DM.

Cancer Discov. 2014 Mar;4(3):278-9. doi: 10.1158/2159-8290.CD-14-0084.

15.

Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development.

Park H, Staehling K, Tsang M, Appleby MW, Brunkow ME, Margineantu D, Hockenbery DM, Habib T, Liggitt HD, Carlson G, Iritani BM.

Immunity. 2012 May 25;36(5):769-81. doi: 10.1016/j.immuni.2012.02.019. Epub 2012 May 17.

16.

Reduced cytochrome C is an essential regulator of sustained insulin secretion by pancreatic islets.

Jung SR, Kuok IT, Couron D, Rizzo N, Margineantu DH, Hockenbery DM, Kim F, Sweet IR.

J Biol Chem. 2011 May 20;286(20):17422-34. doi: 10.1074/jbc.M110.202820. Epub 2011 Mar 10.

17.

Blood and gastric FOXP3+ T cells are not decreased in human gastric graft-versus-host disease.

Lord JD, Hackman RC, Gooley TA, Wood BL, Moklebust AC, Hockenbery DM, Steinbach G, Ziegler SF, McDonald GB.

Biol Blood Marrow Transplant. 2011 Apr;17(4):486-96. doi: 10.1016/j.bbmt.2010.09.015. Epub 2010 Sep 24.

18.

Investigating neoplastic progression of ulcerative colitis with label-free comparative proteomics.

May D, Pan S, Crispin DA, Lai K, Bronner MP, Hogan J, Hockenbery DM, McIntosh M, Brentnall TA, Chen R.

J Proteome Res. 2011 Jan 7;10(1):200-9. doi: 10.1021/pr100574p. Epub 2010 Oct 20.

19.

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells.

Delgado T, Carroll PA, Punjabi AS, Margineantu D, Hockenbery DM, Lagunoff M.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10696-701. doi: 10.1073/pnas.1004882107. Epub 2010 May 24.

20.

Targeting mitochondria for cancer therapy.

Hockenbery DM.

Environ Mol Mutagen. 2010 Jun;51(5):476-89. doi: 10.1002/em.20552. Review.

PMID:
20213841
21.

Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation.

Maloney E, Sweet IR, Hockenbery DM, Pham M, Rizzo NO, Tateya S, Handa P, Schwartz MW, Kim F.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1370-5. doi: 10.1161/ATVBAHA.109.188813. Epub 2009 Jun 18.

22.

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry.

Morrish F, Isern N, Sadilek M, Jeffrey M, Hockenbery DM.

Oncogene. 2009 Jul 9;28(27):2485-91. doi: 10.1038/onc.2009.112. Epub 2009 May 18.

23.

Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration.

Sweet IR, Gilbert M, Maloney E, Hockenbery DM, Schwartz MW, Kim F.

Diabetologia. 2009 May;52(5):921-31. doi: 10.1007/s00125-009-1272-4. Epub 2009 Feb 14.

24.

Bak to basics of colonocyte renewal.

Susnow NJ, Hockenbery DM.

Gastroenterology. 2009 Mar;136(3):763-6. doi: 10.1053/j.gastro.2009.01.021. Epub 2009 Jan 22. No abstract available.

PMID:
19167391
25.

Bcl-2 family proteins as regulators of oxidative stress.

Susnow N, Zeng L, Margineantu D, Hockenbery DM.

Semin Cancer Biol. 2009 Feb;19(1):42-9. doi: 10.1016/j.semcancer.2008.12.002. Epub 2008 Dec 24. Review.

26.

Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals.

Seal S, Hockenbery DM, Spaulding EY, Kiem HP, Abbassi N, Deeg HJ.

Exp Hematol. 2008 Dec;36(12):1660-72. doi: 10.1016/j.exphem.2008.07.012. Epub 2008 Oct 5.

27.

The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry.

Morrish F, Neretti N, Sedivy JM, Hockenbery DM.

Cell Cycle. 2008 Apr 15;7(8):1054-66. Epub 2008 Feb 8.

28.

Hsp90 inhibition decreases mitochondrial protein turnover.

Margineantu DH, Emerson CB, Diaz D, Hockenbery DM.

PLoS One. 2007 Oct 24;2(10):e1066.

29.

Oral beclomethasone dipropionate in gastrointestinal graft-versus-host disease.

Hockenbery DM.

Expert Rev Clin Immunol. 2007 Sep;3(5):695-700. doi: 10.1586/1744666X.3.5.695.

PMID:
20477020
30.

2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition.

Schwartz PS, Manion MK, Emerson CB, Fry JS, Schulz CM, Sweet IR, Hockenbery DM.

Mol Cancer Ther. 2007 Jul;6(7):2073-80.

31.

Loss of FANCC function is associated with failure to inhibit late firing replication origins after DNA cross-linking.

Phelps RA, Gingras H, Hockenbery DM.

Exp Cell Res. 2007 Jul 1;313(11):2283-92. Epub 2007 Apr 6.

PMID:
17490643
32.

Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines.

Ying SX, Seal S, Abbassi N, Hockenbery DM, Kiem HP, Li X, Pagel JM, Gopal AK, Deeg HJ.

Leuk Lymphoma. 2007 May;48(5):1003-14.

PMID:
17487744
33.

Targeted therapies for epithelial cancers: in vivo efficacy of the BCL-2/BCL-XL inhibitor 2-MeAA.

Schwartz PS, Hockenbery DM.

Cancer Biol Ther. 2007 Mar;6(3):465-6. Epub 2007 Mar 15. No abstract available.

PMID:
17471026
34.

A randomized, placebo-controlled trial of oral beclomethasone dipropionate as a prednisone-sparing therapy for gastrointestinal graft-versus-host disease.

Hockenbery DM, Cruickshank S, Rodell TC, Gooley T, Schuening F, Rowley S, David D, Brunvand M, Berryman B, Abhyankar S, Bouvier M, McDonald GB.

Blood. 2007 May 15;109(10):4557-63. Epub 2007 Jan 23.

PMID:
17244684
35.

Small-molecule inhibitors of Bcl-2.

Manion MK, Fry J, Schwartz PS, Hockenbery DM.

Curr Opin Investig Drugs. 2006 Dec;7(12):1077-84. Review.

PMID:
17209525
36.

MMPs in unusual places.

Hockenbery DM.

Am J Pathol. 2006 Oct;169(4):1101-3. No abstract available.

37.

Bcl-2-related survival proteins.

Schwartz PS, Hockenbery DM.

Cell Death Differ. 2006 Aug;13(8):1250-5. Epub 2006 Jun 9. No abstract available.

38.

Gastrointestinal graft-versus-host disease in recipients of autologous hematopoietic stem cells: incidence, risk factors, and outcome.

Holmberg L, Kikuchi K, Gooley TA, Adams KM, Hockenbery DM, Flowers ME, Schoch HG, Bensinger W, McDonald GB.

Biol Blood Marrow Transplant. 2006 Feb;12(2):226-34.

39.

BCL-XL dimerization by three-dimensional domain swapping.

O'Neill JW, Manion MK, Maguire B, Hockenbery DM.

J Mol Biol. 2006 Feb 17;356(2):367-81. Epub 2005 Dec 1.

PMID:
16368107
40.

Efficacy of neodymium:YAG laser therapy for gastric antral vascular ectasia (GAVE) following hematopoietic cell transplant.

Selinger RR, McDonald GB, Hockenbery DM, Steinbach G, Kimmey MB.

Bone Marrow Transplant. 2006 Jan;37(2):191-7.

PMID:
16284614
41.

Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.

Pagel JM, Laugen C, Bonham L, Hackman RC, Hockenbery DM, Bhatt R, Hollenback D, Carew H, Singer JW, Press OW.

Clin Cancer Res. 2005 Jul 1;11(13):4857-66.

42.

Preclinical pharmacology of 2-methoxyantimycin A compounds as novel antitumor agents.

Wang H, Li M, Rhie JK, Hockenbery DM, Covey JM, Zhang R, Hill DL.

Cancer Chemother Pharmacol. 2005 Sep;56(3):291-8. Epub 2005 May 10.

PMID:
15883820
43.

BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death.

Ho HK, Hu ZH, Tzung SP, Hockenbery DM, Fausto N, Nelson SD, Bruschi SA.

Biochem Pharmacol. 2005 Jan 1;69(1):147-57.

PMID:
15588723
44.

Promises and challenges of targeting Bcl-2 anti-apoptotic proteins for cancer therapy.

O'Neill J, Manion M, Schwartz P, Hockenbery DM.

Biochim Biophys Acta. 2004 Dec 10;1705(1):43-51. Review.

PMID:
15585172
45.

A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve system.

Erxleben HA, Manion MK, Hockenbery DM, Scampavia L, Ruzicka J.

Analyst. 2004 Mar;129(3):205-12. Epub 2004 Feb 2.

PMID:
14978521
46.

Identification of androgen-coregulated protein networks from the microsomes of human prostate cancer cells.

Wright ME, Eng J, Sherman J, Hockenbery DM, Nelson PS, Galitski T, Aebersold R.

Genome Biol. 2003;5(1):R4. Epub 2003 Dec 23.

47.

Prevention of Fas-mediated hepatic failure by transferrin.

Lesnikov VA, Lesnikova MP, Shulman HM, Wilson HM, Hockenbery DM, Kocher M, Pierpaoli W, Deeg HJ.

Lab Invest. 2004 Mar;84(3):342-52.

48.

Bcl-XL mutations suppress cellular sensitivity to antimycin A.

Manion MK, O'Neill JW, Giedt CD, Kim KM, Zhang KY, Hockenbery DM.

J Biol Chem. 2004 Jan 16;279(3):2159-65. Epub 2003 Oct 8.

49.

Targeting BCL-2-related proteins in cancer therapy.

Manion MK, Hockenbery DM.

Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S105-14. Review.

PMID:
14508087
50.

Successful medical treatment of intestinal ulceration caused by Rhizopus microsporus.

Pinto-Marques P, Hockenbery DM, Hackman RC, Tapper D, McDonald GB.

Bone Marrow Transplant. 2003 Oct;32(7):739-40. No abstract available.

PMID:
13130324

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