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Items: 1 to 50 of 117

1.

Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans.

Lampe JW, Kim E, Levy L, Davidson LA, Goldsby JS, Miles FL, Navarro SL, Randolph TW, Zhao N, Ivanov I, Kaz AM, Damman C, Hockenbery DM, Hullar MAJ, Chapkin RS.

Am J Clin Nutr. 2019 Aug 1;110(2):377-390. doi: 10.1093/ajcn/nqy325.

PMID:
31175806
2.

Analysis of the Myc-induced pancreatic β cell islet tumor microenvironment using imaging ToF-SIMS.

Bluestein BM, Morrish F, Graham DJ, Huang L, Hockenbery D, Gamble LJ.

Biointerphases. 2018 Aug 28;13(6):06D402. doi: 10.1116/1.5038574.

PMID:
30153736
3.

Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.

Centini R, Tsang M, Iwata T, Park H, Delrow J, Margineantu D, Iritani BM, Gu H, Liggitt HD, Kang J, Kang L, Hockenbery DM, Raftery D, Iritani BM.

PLoS One. 2018 Jun 13;13(6):e0197973. doi: 10.1371/journal.pone.0197973. eCollection 2018.

4.

A Metabolomics Study of BPTES Altered Metabolism in Human Breast Cancer Cell Lines.

Nagana Gowda GA, Barding GA Jr, Dai J, Gu H, Margineantu DH, Hockenbery DM, Raftery D.

Front Mol Biosci. 2018 May 15;5:49. doi: 10.3389/fmolb.2018.00049. eCollection 2018.

5.

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.

Davis RJ, Gönen M, Margineantu DH, Handeli S, Swanger J, Hoellerbauer P, Paddison PJ, Gu H, Raftery D, Grim JE, Hockenbery DM, Margolin AA, Clurman BE.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):5462-5467. doi: 10.1073/pnas.1718338115. Epub 2018 May 7.

6.

Inhibition of vaccinia virus replication by nitazoxanide.

Hickson SE, Margineantu D, Hockenbery DM, Simon JA, Geballe AP.

Virology. 2018 May;518:398-405. doi: 10.1016/j.virol.2018.03.023. Epub 2018 Apr 3.

7.

Pathological assessment of gastrointestinal biopsies from patients with idelalisib-associated diarrhea and colitis.

Yeung CC, Hockenbery DM, Westerhoff M, Coutre SE, Sedlak RH, Dubowy RL, Munugalavadla V, Taylor K, Bosch F.

Future Oncol. 2018 Sep;14(22):2265-2277. doi: 10.2217/fon-2017-0528. Epub 2018 Mar 23.

8.

Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease.

Steinbach G, Hockenbery DM, Huls G, Furlong T, Myerson D, Loeb KR, Fann JR, Castilla-Llorente C, McDonald GB, Martin PJ.

PLoS One. 2017 Aug 17;12(8):e0183284. doi: 10.1371/journal.pone.0183284. eCollection 2017.

9.

Mutant IDH1 regulates the tumor-associated immune system in gliomas.

Amankulor NM, Kim Y, Arora S, Kargl J, Szulzewsky F, Hanke M, Margineantu DH, Rao A, Bolouri H, Delrow J, Hockenbery D, Houghton AM, Holland EC.

Genes Dev. 2017 Apr 15;31(8):774-786. doi: 10.1101/gad.294991.116. Epub 2017 May 2.

10.

Enzyme-Cleavable Polymeric Micelles for the Intracellular Delivery of Proapoptotic Peptides.

Kern HB, Srinivasan S, Convertine AJ, Hockenbery D, Press OW, Stayton PS.

Mol Pharm. 2017 May 1;14(5):1450-1459. doi: 10.1021/acs.molpharmaceut.6b01178. Epub 2017 Mar 30.

11.

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.

Berger S, Procko E, Margineantu D, Lee EF, Shen BW, Zelter A, Silva DA, Chawla K, Herold MJ, Garnier JM, Johnson R, MacCoss MJ, Lessene G, Davis TN, Stayton PS, Stoddard BL, Fairlie WD, Hockenbery DM, Baker D.

Elife. 2016 Nov 2;5. pii: e20352. doi: 10.7554/eLife.20352.

12.

Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.

Iwata TN, Ramírez JA, Tsang M, Park H, Margineantu DH, Hockenbery DM, Iritani BM.

J Immunol. 2016 Sep 15;197(6):2250-60. doi: 10.4049/jimmunol.1600492. Epub 2016 Aug 12.

13.

Mitochondrial functions in stem cells.

Margineantu DH, Hockenbery DM.

Curr Opin Genet Dev. 2016 Jun;38:110-117. doi: 10.1016/j.gde.2016.05.004. Epub 2016 Jun 5. Review.

PMID:
27269732
14.

Response of Steroid-Refractory Acute GVHD to α1-Antitrypsin.

Marcondes AM, Hockenbery D, Lesnikova M, Dinarello CA, Woolfrey A, Gernsheimer T, Loghman-Adham M, Gelmont D, Storer B, Hansen JA, Deeg HJ.

Biol Blood Marrow Transplant. 2016 Sep;22(9):1596-1601. doi: 10.1016/j.bbmt.2016.05.011. Epub 2016 May 17.

15.

Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program.

Aguilar E, Marin de Mas I, Zodda E, Marin S, Morrish F, Selivanov V, Meca-Cortés Ó, Delowar H, Pons M, Izquierdo I, Celià-Terrassa T, de Atauri P, Centelles JJ, Hockenbery D, Thomson TM, Cascante M.

Stem Cells. 2016 May;34(5):1163-76. doi: 10.1002/stem.2286. Epub 2016 Feb 2.

16.

An unsupervised MVA method to compare specific regions in human breast tumor tissue samples using ToF-SIMS.

Bluestein BM, Morrish F, Graham DJ, Guenthoer J, Hockenbery D, Porter PL, Gamble LJ.

Analyst. 2016 Mar 21;141(6):1947-57. doi: 10.1039/c5an02406d.

17.

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.

Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H.

Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16.

18.

Lipid analysis of eight human breast cancer cell lines with ToF-SIMS.

Robinson MA, Graham DJ, Morrish F, Hockenbery D, Gamble LJ.

Biointerphases. 2015 Jun 28;11(2):02A303. doi: 10.1116/1.4929633.

19.

ToF-SIMS of tissues: "lessons learned" from mice and women.

Gamble LJ, Graham DJ, Bluestein B, Whitehead NP, Hockenbery D, Morrish F, Porter P.

Biointerphases. 2015 Mar 13;10(1):019008. doi: 10.1116/1.4907860.

20.

Intracellular delivery system for antibody-Peptide drug conjugates.

Berguig GY, Convertine AJ, Frayo S, Kern HB, Procko E, Roy D, Srinivasan S, Margineantu DH, Booth G, Palanca-Wessels MC, Baker D, Hockenbery D, Press OW, Stayton PS.

Mol Ther. 2015 May;23(5):907-917. doi: 10.1038/mt.2015.22. Epub 2015 Feb 11.

21.

Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy.

Reyes NL, Banks GB, Tsang M, Margineantu D, Gu H, Djukovic D, Chan J, Torres M, Liggitt HD, Hirenallur-S DK, Hockenbery DM, Raftery D, Iritani BM.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):424-9. doi: 10.1073/pnas.1413021112. Epub 2014 Dec 29.

22.

Fibrosing cholestatic hepatitis C after hematopoietic cell transplantation: report of 3 fatal cases.

Evans AT, Loeb KR, Shulman HM, Hassan S, Qiu WC, Hockenbery DM, Ioannou GN, Chauncey TR, Gretch DR, McDonald GB.

Am J Surg Pathol. 2015 Feb;39(2):212-20. doi: 10.1097/PAS.0000000000000345.

PMID:
25517948
23.

α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics.

Marcondes AM, Karoopongse E, Lesnikova M, Margineantu D, Welte T, Dinarello CA, Hockenbery D, Janciauskiene S, Deeg HJ.

Blood. 2014 Oct 30;124(18):2881-91. doi: 10.1182/blood-2014-04-570440. Epub 2014 Sep 15.

24.

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells.

Procko E, Berguig GY, Shen BW, Song Y, Frayo S, Convertine AJ, Margineantu D, Booth G, Correia BE, Cheng Y, Schief WR, Hockenbery DM, Press OW, Stoddard BL, Stayton PS, Baker D.

Cell. 2014 Jun 19;157(7):1644-1656. doi: 10.1016/j.cell.2014.04.034.

25.

MYC and mitochondrial biogenesis.

Morrish F, Hockenbery D.

Cold Spring Harb Perspect Med. 2014 May 1;4(5). pii: a014225. doi: 10.1101/cshperspect.a014225. Review.

26.

Forecast: rough seas for leukemia.

Hockenbery DM.

Cancer Discov. 2014 Mar;4(3):278-9. doi: 10.1158/2159-8290.CD-14-0084.

27.

Warburg and Crabtree effects in premalignant Barrett's esophagus cell lines with active mitochondria.

Suchorolski MT, Paulson TG, Sanchez CA, Hockenbery D, Reid BJ.

PLoS One. 2013;8(2):e56884. doi: 10.1371/journal.pone.0056884. Epub 2013 Feb 27.

28.

Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development.

Park H, Staehling K, Tsang M, Appleby MW, Brunkow ME, Margineantu D, Hockenbery DM, Habib T, Liggitt HD, Carlson G, Iritani BM.

Immunity. 2012 May 25;36(5):769-81. doi: 10.1016/j.immuni.2012.02.019. Epub 2012 May 17.

29.

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition.

Zhou W, Choi M, Margineantu D, Margaretha L, Hesson J, Cavanaugh C, Blau CA, Horwitz MS, Hockenbery D, Ware C, Ruohola-Baker H.

EMBO J. 2012 May 2;31(9):2103-16. doi: 10.1038/emboj.2012.71. Epub 2012 Mar 23.

30.

Reduced cytochrome C is an essential regulator of sustained insulin secretion by pancreatic islets.

Jung SR, Kuok IT, Couron D, Rizzo N, Margineantu DH, Hockenbery DM, Kim F, Sweet IR.

J Biol Chem. 2011 May 20;286(20):17422-34. doi: 10.1074/jbc.M110.202820. Epub 2011 Mar 10.

31.

Blood and gastric FOXP3+ T cells are not decreased in human gastric graft-versus-host disease.

Lord JD, Hackman RC, Gooley TA, Wood BL, Moklebust AC, Hockenbery DM, Steinbach G, Ziegler SF, McDonald GB.

Biol Blood Marrow Transplant. 2011 Apr;17(4):486-96. doi: 10.1016/j.bbmt.2010.09.015. Epub 2010 Sep 24.

32.

Investigating neoplastic progression of ulcerative colitis with label-free comparative proteomics.

May D, Pan S, Crispin DA, Lai K, Bronner MP, Hogan J, Hockenbery DM, McIntosh M, Brentnall TA, Chen R.

J Proteome Res. 2011 Jan 7;10(1):200-9. doi: 10.1021/pr100574p. Epub 2010 Oct 20.

33.

Myc-dependent mitochondrial generation of acetyl-CoA contributes to fatty acid biosynthesis and histone acetylation during cell cycle entry.

Morrish F, Noonan J, Perez-Olsen C, Gafken PR, Fitzgibbon M, Kelleher J, VanGilst M, Hockenbery D.

J Biol Chem. 2010 Nov 19;285(47):36267-74. doi: 10.1074/jbc.M110.141606. Epub 2010 Sep 2. Erratum in: J Biol Chem. 2011 Mar 11;286(10):8708.

34.

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells.

Delgado T, Carroll PA, Punjabi AS, Margineantu D, Hockenbery DM, Lagunoff M.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10696-701. doi: 10.1073/pnas.1004882107. Epub 2010 May 24.

35.

Targeting mitochondria for cancer therapy.

Hockenbery DM.

Environ Mol Mutagen. 2010 Jun;51(5):476-89. doi: 10.1002/em.20552. Review.

PMID:
20213841
36.

Cyclin I activates Cdk5 and regulates expression of Bcl-2 and Bcl-XL in postmitotic mouse cells.

Brinkkoetter PT, Olivier P, Wu JS, Henderson S, Krofft RD, Pippin JW, Hockenbery D, Roberts JM, Shankland SJ.

J Clin Invest. 2009 Oct;119(10):3089-101. doi: 10.1172/JCI37978. Epub 2009 Sep 1.

37.

Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation.

Maloney E, Sweet IR, Hockenbery DM, Pham M, Rizzo NO, Tateya S, Handa P, Schwartz MW, Kim F.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1370-5. doi: 10.1161/ATVBAHA.109.188813. Epub 2009 Jun 18.

38.

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry.

Morrish F, Isern N, Sadilek M, Jeffrey M, Hockenbery DM.

Oncogene. 2009 Jul 9;28(27):2485-91. doi: 10.1038/onc.2009.112. Epub 2009 May 18.

39.

Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration.

Sweet IR, Gilbert M, Maloney E, Hockenbery DM, Schwartz MW, Kim F.

Diabetologia. 2009 May;52(5):921-31. doi: 10.1007/s00125-009-1272-4. Epub 2009 Feb 14.

40.

Bak to basics of colonocyte renewal.

Susnow NJ, Hockenbery DM.

Gastroenterology. 2009 Mar;136(3):763-6. doi: 10.1053/j.gastro.2009.01.021. Epub 2009 Jan 22. No abstract available.

PMID:
19167391
41.

Bcl-2 family proteins as regulators of oxidative stress.

Susnow N, Zeng L, Margineantu D, Hockenbery DM.

Semin Cancer Biol. 2009 Feb;19(1):42-9. doi: 10.1016/j.semcancer.2008.12.002. Epub 2008 Dec 24. Review.

42.

Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals.

Seal S, Hockenbery DM, Spaulding EY, Kiem HP, Abbassi N, Deeg HJ.

Exp Hematol. 2008 Dec;36(12):1660-72. doi: 10.1016/j.exphem.2008.07.012. Epub 2008 Oct 5.

43.

The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry.

Morrish F, Neretti N, Sedivy JM, Hockenbery DM.

Cell Cycle. 2008 Apr 15;7(8):1054-66. Epub 2008 Feb 8.

44.

Hsp90 inhibition decreases mitochondrial protein turnover.

Margineantu DH, Emerson CB, Diaz D, Hockenbery DM.

PLoS One. 2007 Oct 24;2(10):e1066.

45.

Identification of genes with abnormal expression changes in acute myeloid leukemia.

Stirewalt DL, Meshinchi S, Kopecky KJ, Fan W, Pogosova-Agadjanyan EL, Engel JH, Cronk MR, Dorcy KS, McQuary AR, Hockenbery D, Wood B, Heimfeld S, Radich JP.

Genes Chromosomes Cancer. 2008 Jan;47(1):8-20.

PMID:
17910043
46.

Oral beclomethasone dipropionate in gastrointestinal graft-versus-host disease.

Hockenbery DM.

Expert Rev Clin Immunol. 2007 Sep;3(5):695-700. doi: 10.1586/1744666X.3.5.695.

PMID:
20477020
47.

2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition.

Schwartz PS, Manion MK, Emerson CB, Fry JS, Schulz CM, Sweet IR, Hockenbery DM.

Mol Cancer Ther. 2007 Jul;6(7):2073-80.

48.

Loss of FANCC function is associated with failure to inhibit late firing replication origins after DNA cross-linking.

Phelps RA, Gingras H, Hockenbery DM.

Exp Cell Res. 2007 Jul 1;313(11):2283-92. Epub 2007 Apr 6.

PMID:
17490643
49.

Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines.

Ying SX, Seal S, Abbassi N, Hockenbery DM, Kiem HP, Li X, Pagel JM, Gopal AK, Deeg HJ.

Leuk Lymphoma. 2007 May;48(5):1003-14.

PMID:
17487744
50.

Targeted therapies for epithelial cancers: in vivo efficacy of the BCL-2/BCL-XL inhibitor 2-MeAA.

Schwartz PS, Hockenbery DM.

Cancer Biol Ther. 2007 Mar;6(3):465-6. Epub 2007 Mar 15. No abstract available.

PMID:
17471026

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