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Items: 39


Structure and function of the Orc1 BAH-nucleosome complex.

De Ioannes P, Leon VA, Kuang Z, Wang M, Boeke JD, Hochwagen A, Armache KJ.

Nat Commun. 2019 Jul 1;10(1):2894. doi: 10.1038/s41467-019-10609-y.


Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes.

Subramanian VV, Zhu X, Markowitz TE, Vale-Silva LA, San-Segundo PA, Hollingsworth NM, Keeney S, Hochwagen A.

Nat Commun. 2019 Feb 27;10(1):970. doi: 10.1038/s41467-019-08875-x.


SNP-ChIP: a versatile and tag-free method to quantify changes in protein binding across the genome.

Vale-Silva LA, Markowitz TE, Hochwagen A.

BMC Genomics. 2019 Jan 17;20(1):54. doi: 10.1186/s12864-018-5368-4.


Condensin action and compaction.

Paul MR, Hochwagen A, Ercan S.

Curr Genet. 2019 Apr;65(2):407-415. doi: 10.1007/s00294-018-0899-4. Epub 2018 Oct 25. Review.


Genomic Copy-Number Loss Is Rescued by Self-Limiting Production of DNA Circles.

Mansisidor A, Molinar T Jr, Srivastava P, Dartis DD, Pino Delgado A, Blitzblau HG, Klein H, Hochwagen A.

Mol Cell. 2018 Nov 1;72(3):583-593.e4. doi: 10.1016/j.molcel.2018.08.036. Epub 2018 Oct 4.


Condensin Depletion Causes Genome Decompaction Without Altering the Level of Global Gene Expression in Saccharomyces cerevisiae.

Paul MR, Markowitz TE, Hochwagen A, Ercan S.

Genetics. 2018 Sep;210(1):331-344. doi: 10.1534/genetics.118.301217. Epub 2018 Jul 3.


Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae.

Markowitz TE, Suarez D, Blitzblau HG, Patel NJ, Markhard AL, MacQueen AJ, Hochwagen A.

PLoS Genet. 2017 Jul 26;13(7):e1006928. doi: 10.1371/journal.pgen.1006928. eCollection 2017 Jul.


Fundamental cell cycle kinases collaborate to ensure timely destruction of the synaptonemal complex during meiosis.

Argunhan B, Leung WK, Afshar N, Terentyev Y, Subramanian VV, Murayama Y, Hochwagen A, Iwasaki H, Tsubouchi T, Tsubouchi H.

EMBO J. 2017 Sep 1;36(17):2488-2509. doi: 10.15252/embj.201695895. Epub 2017 Jul 10.


Condensin and Hmo1 Mediate a Starvation-Induced Transcriptional Position Effect within the Ribosomal DNA Array.

Wang D, Mansisidor A, Prabhakar G, Hochwagen A.

Cell Rep. 2016 Oct 4;17(2):624. doi: 10.1016/j.celrep.2016.09.057. No abstract available.


Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair.

Subramanian VV, MacQueen AJ, Vader G, Shinohara M, Sanchez A, Borde V, Shinohara A, Hochwagen A.

PLoS Biol. 2016 Feb 12;14(2):e1002369. doi: 10.1371/journal.pbio.1002369. eCollection 2016 Feb.


Condensin and Hmo1 Mediate a Starvation-Induced Transcriptional Position Effect within the Ribosomal DNA Array.

Wang D, Mansisidor A, Prabhakar G, Hochwagen A.

Cell Rep. 2016 Feb 9;14(5):1010-1017. doi: 10.1016/j.celrep.2016.01.005. Epub 2016 Jan 28. Erratum in: Cell Rep. 2016 Oct 4;17 (2):624.


Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS Complex.

He H, Zhang S, Wang D, Hochwagen A, Li F.

Cell Rep. 2016 Feb 9;14(5):1018-1024. doi: 10.1016/j.celrep.2016.01.006. Epub 2016 Jan 28.


The kinetochore prevents centromere-proximal crossover recombination during meiosis.

Vincenten N, Kuhl LM, Lam I, Oke A, Kerr AR, Hochwagen A, Fung J, Keeney S, Vader G, Marston AL.

Elife. 2015 Dec 14;4. pii: e10850. doi: 10.7554/eLife.10850.


The Double-Strand Break Landscape of Meiotic Chromosomes Is Shaped by the Paf1 Transcription Elongation Complex in Saccharomyces cerevisiae.

Gothwal SK, Patel NJ, Colletti MM, Sasanuma H, Shinohara M, Hochwagen A, Shinohara A.

Genetics. 2016 Feb;202(2):497-512. doi: 10.1534/genetics.115.177287. Epub 2015 Dec 1.


Transcription dynamically patterns the meiotic chromosome-axis interface.

Sun X, Huang L, Markowitz TE, Blitzblau HG, Chen D, Klein F, Hochwagen A.

Elife. 2015 Aug 10;4. doi: 10.7554/eLife.07424.


Separable Crossover-Promoting and Crossover-Constraining Aspects of Zip1 Activity during Budding Yeast Meiosis.

Voelkel-Meiman K, Johnston C, Thappeta Y, Subramanian VV, Hochwagen A, MacQueen AJ.

PLoS Genet. 2015 Jun 26;11(6):e1005335. doi: 10.1371/journal.pgen.1005335. eCollection 2015 Jun.


The meiotic checkpoint network: step-by-step through meiotic prophase.

Subramanian VV, Hochwagen A.

Cold Spring Harb Perspect Biol. 2014 Oct 1;6(10):a016675. doi: 10.1101/cshperspect.a016675. Review.


A non-sister act: recombination template choice during meiosis.

Humphryes N, Hochwagen A.

Exp Cell Res. 2014 Nov 15;329(1):53-60. doi: 10.1016/j.yexcr.2014.08.024. Epub 2014 Aug 23. Review.


Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions.

Copsey A, Tang S, Jordan PW, Blitzblau HG, Newcombe S, Chan AC, Newnham L, Li Z, Gray S, Herbert AD, Arumugam P, Hochwagen A, Hunter N, Hoffmann E.

PLoS Genet. 2013;9(12):e1004071. doi: 10.1371/journal.pgen.1004071. Epub 2013 Dec 26.


RNA methylation by the MIS complex regulates a cell fate decision in yeast.

Agarwala SD, Blitzblau HG, Hochwagen A, Fink GR.

PLoS Genet. 2012;8(6):e1002732. doi: 10.1371/journal.pgen.1002732. Epub 2012 Jun 7.


Separation of DNA replication from the assembly of break-competent meiotic chromosomes.

Blitzblau HG, Chan CS, Hochwagen A, Bell SP.

PLoS Genet. 2012;8(5):e1002643. doi: 10.1371/journal.pgen.1002643. Epub 2012 May 17.


Centromere clustering: where synapsis begins.

Subramanian VV, Hochwagen A.

Curr Biol. 2011 Nov 22;21(22):R920-2. doi: 10.1016/j.cub.2011.10.023. Erratum in: Curr Biol. 2011 Dec 20;21(24):2121.


Protection of repetitive DNA borders from self-induced meiotic instability.

Vader G, Blitzblau HG, Tame MA, Falk JE, Curtin L, Hochwagen A.

Nature. 2011 Aug 7;477(7362):115-9. doi: 10.1038/nature10331.


Genome-wide detection of meiotic DNA double-strand break hotspots using single-stranded DNA.

Blitzblau HG, Hochwagen A.

Methods Mol Biol. 2011;745:47-63. doi: 10.1007/978-1-61779-129-1_4.


Checkpoint mechanisms: the puppet masters of meiotic prophase.

MacQueen AJ, Hochwagen A.

Trends Cell Biol. 2011 Jul;21(7):393-400. doi: 10.1016/j.tcb.2011.03.004. Epub 2011 Apr 29. Review.


A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation.

Pan J, Sasaki M, Kniewel R, Murakami H, Blitzblau HG, Tischfield SE, Zhu X, Neale MJ, Jasin M, Socci ND, Hochwagen A, Keeney S.

Cell. 2011 Mar 4;144(5):719-31. doi: 10.1016/j.cell.2011.02.009.


A Mec1- and PP4-dependent checkpoint couples centromere pairing to meiotic recombination.

Falk JE, Chan AC, Hoffmann E, Hochwagen A.

Dev Cell. 2010 Oct 19;19(4):599-611. doi: 10.1016/j.devcel.2010.09.006.


Meiosis: a PRDM9 guide to the hotspots of recombination.

Hochwagen A, Marais GA.

Curr Biol. 2010 Mar 23;20(6):R271-4. doi: 10.1016/j.cub.2010.01.048. No abstract available.


Meiosis: making a synaptonemal complex just got easier.

Hochwagen A.

Curr Biol. 2009 Sep 29;19(18):R849-51. doi: 10.1016/j.cub.2009.07.001.


The multiple roles of cohesin in meiotic chromosome morphogenesis and pairing.

Brar GA, Hochwagen A, Ee LS, Amon A.

Mol Biol Cell. 2009 Feb;20(3):1030-47. doi: 10.1091/mbc.E08-06-0637. Epub 2008 Dec 10.


Global analysis of the meiotic crossover landscape.

Chen SY, Tsubouchi T, Rockmill B, Sandler JS, Richards DR, Vader G, Hochwagen A, Roeder GS, Fung JC.

Dev Cell. 2008 Sep;15(3):401-15. doi: 10.1016/j.devcel.2008.07.006. Epub 2008 Aug 7.



Hochwagen A.

Curr Biol. 2008 Aug 5;18(15):R641-R645. doi: 10.1016/j.cub.2008.06.013. No abstract available.


Mapping of meiotic single-stranded DNA reveals double-stranded-break hotspots near centromeres and telomeres.

Blitzblau HG, Bell GW, Rodriguez J, Bell SP, Hochwagen A.

Curr Biol. 2007 Dec 4;17(23):2003-12.


Checking your breaks: surveillance mechanisms of meiotic recombination.

Hochwagen A, Amon A.

Curr Biol. 2006 Mar 21;16(6):R217-28. Review.


Novel response to microtubule perturbation in meiosis.

Hochwagen A, Wrobel G, Cartron M, Demougin P, Niederhauser-Wiederkehr C, Boselli MG, Primig M, Amon A.

Mol Cell Biol. 2005 Jun;25(11):4767-81.


Molecular architecture of SMC proteins and the yeast cohesin complex.

Haering CH, Löwe J, Hochwagen A, Nasmyth K.

Mol Cell. 2002 Apr;9(4):773-88.


Pds5 cooperates with cohesin in maintaining sister chromatid cohesion.

Panizza S, Tanaka T, Hochwagen A, Eisenhaber F, Nasmyth K.

Curr Biol. 2000 Dec 14-28;10(24):1557-64.

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