Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 293

1.

Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies.

Medina-Echeverz J, Hinterberger M, Testori M, Geiger M, Giessel R, Bathke B, Kassub R, Gräbnitz F, Fiore G, Wennier ST, Chaplin P, Suter M, Hochrein H, Lauterbach H.

Nat Commun. 2019 Nov 6;10(1):5041. doi: 10.1038/s41467-019-12998-6.

2.

4PNovel applications of MVA to improve outcomes in immunooncology.

Heery C, Pico-Navarro C, Adams T, Bauman L, Medina J, Hinterberger M, Heiseke A, Lauterbach H, Hochrein H.

Ann Oncol. 2019 Feb 1;30(Supplement_1). pii: mdz027.002. doi: 10.1093/annonc/mdz027.002. No abstract available.

PMID:
30810176
3.

PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.

Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D.

Nat Immunol. 2018 Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13.

4.

Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia.

Robak OH, Heimesaat MM, Kruglov AA, Prepens S, Ninnemann J, Gutbier B, Reppe K, Hochrein H, Suter M, Kirschning CJ, Marathe V, Buer J, Hornef MW, Schnare M, Schneider P, Witzenrath M, Bereswill S, Steinhoff U, Suttorp N, Sander LE, Chaput C, Opitz B.

J Clin Invest. 2018 Aug 1;128(8):3535-3545. doi: 10.1172/JCI97065. Epub 2018 Jul 16.

5.

NLRC4 Inflammasome-Driven Immunogenicity of a Recombinant MVA Mucosal Vaccine Encoding Flagellin.

Sanos SL, Kassub R, Testori M, Geiger M, Pätzold J, Giessel R, Knallinger J, Bathke B, Gräbnitz F, Brinkmann K, Chaplin P, Suter M, Hochrein H, Lauterbach H.

Front Immunol. 2018 Jan 24;8:1988. doi: 10.3389/fimmu.2017.01988. eCollection 2017.

6.

CD70 encoded by modified vaccinia virus Ankara enhances CD8 T-cell-dependent protective immunity in MHC class II-deficient mice.

Bathke B, Pätzold J, Kassub R, Giessel R, Lämmermann K, Hinterberger M, Brinkmann K, Chaplin P, Suter M, Hochrein H, Lauterbach H.

Immunology. 2018 Jun;154(2):285-297. doi: 10.1111/imm.12884. Epub 2018 Jan 26.

7.

MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica.

Winkler HC, Kornprobst J, Wick P, von Moos LM, Trantakis I, Schraner EM, Bathke B, Hochrein H, Suter M, Naegeli H.

Part Fibre Toxicol. 2017 Jun 23;14(1):21. doi: 10.1186/s12989-017-0202-8.

8.

Recombinant Modified Vaccinia Virus Ankara Generating Ebola Virus-Like Particles.

Schweneker M, Laimbacher AS, Zimmer G, Wagner S, Schraner EM, Wolferstätter M, Klingenberg M, Dirmeier U, Steigerwald R, Lauterbach H, Hochrein H, Chaplin P, Suter M, Hausmann J.

J Virol. 2017 May 12;91(11). pii: e00343-17. doi: 10.1128/JVI.00343-17. Print 2017 Jun 1.

9.

Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA.

Krüger A, Oldenburg M, Chebrolu C, Beisser D, Kolter J, Sigmund AM, Steinmann J, Schäfer S, Hochrein H, Rahmann S, Wagner H, Henneke P, Hornung V, Buer J, Kirschning CJ.

EMBO Rep. 2015 Dec;16(12):1656-63. doi: 10.15252/embr.201540861. Epub 2015 Nov 6.

10.

Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production.

Niedzielska M, Raffi FA, Tel J, Muench S, Jozefowski K, Alati N, Lahl K, Mages J, Billmeier U, Schiemann M, Appelt UK, Wirtz S, Sparwasser T, Hochrein H, Figdor CG, Keyse SM, Lang R.

J Immunol. 2015 Aug 15;195(4):1753-62. doi: 10.4049/jimmunol.1400658. Epub 2015 Jul 13.

11.

Recombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses.

Wolferstätter M, Schweneker M, Späth M, Lukassen S, Klingenberg M, Brinkmann K, Wielert U, Lauterbach H, Hochrein H, Chaplin P, Suter M, Hausmann J.

J Virol. 2014 Dec;88(24):14396-411. doi: 10.1128/JVI.02082-14. Epub 2014 Oct 8.

12.

Genetic Adjuvantation of Recombinant MVA with CD40L Potentiates CD8 T Cell Mediated Immunity.

Lauterbach H, Pätzold J, Kassub R, Bathke B, Brinkmann K, Chaplin P, Suter M, Hochrein H.

Front Immunol. 2013 Aug 27;4:251. doi: 10.3389/fimmu.2013.00251. eCollection 2013.

13.
14.

TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification.

Oldenburg M, Krüger A, Ferstl R, Kaufmann A, Nees G, Sigmund A, Bathke B, Lauterbach H, Suter M, Dreher S, Koedel U, Akira S, Kawai T, Buer J, Wagner H, Bauer S, Hochrein H, Kirschning CJ.

Science. 2012 Aug 31;337(6098):1111-5. doi: 10.1126/science.1220363. Epub 2012 Jul 19.

15.

Nonplasmacytoid, high IFN-α-producing, bone marrow dendritic cells.

O'Keeffe M, Fancke B, Suter M, Ramm G, Clark J, Wu L, Hochrein H.

J Immunol. 2012 Apr 15;188(8):3774-83. doi: 10.4049/jimmunol.1101365. Epub 2012 Mar 14.

16.

Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.

Lauterbach H, Bathke B, Gilles S, Traidl-Hoffmann C, Luber CA, Fejer G, Freudenberg MA, Davey GM, Vremec D, Kallies A, Wu L, Shortman K, Chaplin P, Suter M, O'Keeffe M, Hochrein H.

J Exp Med. 2010 Nov 22;207(12):2703-17. doi: 10.1084/jem.20092720. Epub 2010 Oct 25.

17.

A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC?

Bauer S, Bathke B, Lauterbach H, Pätzold J, Kassub R, Luber CA, Schlatter B, Hamm S, Chaplin P, Suter M, Hochrein H.

Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):E139; author reply E140. doi: 10.1073/pnas.1008626107. Epub 2010 Aug 2. No abstract available.

18.

Immune requirements of post-exposure immunization with modified vaccinia Ankara of lethally infected mice.

Lauterbach H, Kassub R, Pätzold J, Körner J, Brückel M, Verschoor A, Chaplin P, Suter M, Hochrein H.

PLoS One. 2010 Mar 11;5(3):e9659. doi: 10.1371/journal.pone.0009659.

19.

Quantitative proteomics reveals subset-specific viral recognition in dendritic cells.

Luber CA, Cox J, Lauterbach H, Fancke B, Selbach M, Tschopp J, Akira S, Wiegand M, Hochrein H, O'Keeffe M, Mann M.

Immunity. 2010 Feb 26;32(2):279-89. doi: 10.1016/j.immuni.2010.01.013. Epub 2010 Feb 18.

20.

The generation of plasmacytoid and conventional dendritic cells with M-CSF.

O'Keeffe M, Fancke B, Hochrein H.

Methods Mol Biol. 2010;595:187-93. doi: 10.1007/978-1-60761-421-0_12.

PMID:
19941113
21.

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection.

Samuelsson C, Hausmann J, Lauterbach H, Schmidt M, Akira S, Wagner H, Chaplin P, Suter M, O'Keeffe M, Hochrein H.

J Clin Invest. 2008 May;118(5):1776-84. doi: 10.1172/JCI33940.

22.

Dendritic cell subsets and toll-like receptors.

Hochrein H, O'Keeffe M.

Handb Exp Pharmacol. 2008;(183):153-79. Review.

PMID:
18071659
23.

M-CSF: a novel plasmacytoid and conventional dendritic cell poietin.

Fancke B, Suter M, Hochrein H, O'Keeffe M.

Blood. 2008 Jan 1;111(1):150-9. Epub 2007 Oct 4.

PMID:
17916748
24.

Cellular recognition of trimyristoylated peptide or enterobacterial lipopolysaccharide via both TLR2 and TLR4.

Spiller S, Dreher S, Meng G, Grabiec A, Thomas W, Hartung T, Pfeffer K, Hochrein H, Brade H, Bessler W, Wagner H, Kirschning CJ.

J Biol Chem. 2007 May 4;282(18):13190-8. Epub 2007 Mar 12.

25.

Production of interferons by dendritic cells, plasmacytoid cells, natural killer cells, and interferon-producing killer dendritic cells.

Vremec D, O'Keeffe M, Hochrein H, Fuchsberger M, Caminschi I, Lahoud M, Shortman K.

Blood. 2007 Feb 1;109(3):1165-73. Epub 2006 Oct 12.

PMID:
17038535
26.

CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen.

Neuenhahn M, Kerksiek KM, Nauerth M, Suhre MH, Schiemann M, Gebhardt FE, Stemberger C, Panthel K, Schröder S, Chakraborty T, Jung S, Hochrein H, Rüssmann H, Brocker T, Busch DH.

Immunity. 2006 Oct;25(4):619-30. Epub 2006 Oct 5.

27.

Adenovirus efficiently transduces plasmacytoid dendritic cells resulting in TLR9-dependent maturation and IFN-alpha production.

Basner-Tschakarjan E, Gaffal E, O'Keeffe M, Tormo D, Limmer A, Wagner H, Hochrein H, Tüting T.

J Gene Med. 2006 Nov;8(11):1300-6.

PMID:
16952196
28.

The long-term but not the short-term antiviral effect of IFN-alpha depends on Flt3 ligand and pDC.

Vollstedt S, O'Keeffe M, Ryf B, Glanzmann B, Hochrein H, Suter M.

Eur J Immunol. 2006 May;36(5):1231-40.

29.

Activation of plasmacytoid dendritic cells.

Fuchsberger M, Hochrein H, O'Keeffe M.

Immunol Cell Biol. 2005 Oct;83(5):571-7. Review.

PMID:
16174109
30.

Distinct roles for the NF-kappaB1 and c-Rel transcription factors in the differentiation and survival of plasmacytoid and conventional dendritic cells activated by TLR-9 signals.

O'Keeffe M, Grumont RJ, Hochrein H, Fuchsberger M, Gugasyan R, Vremec D, Shortman K, Gerondakis S.

Blood. 2005 Nov 15;106(10):3457-64. Epub 2005 Jul 21.

PMID:
16037393
31.

Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways.

Yasuda K, Yu P, Kirschning CJ, Schlatter B, Schmitz F, Heit A, Bauer S, Hochrein H, Wagner H.

J Immunol. 2005 May 15;174(10):6129-36.

32.

Pollen-associated phytoprostanes inhibit dendritic cell interleukin-12 production and augment T helper type 2 cell polarization.

Traidl-Hoffmann C, Mariani V, Hochrein H, Karg K, Wagner H, Ring J, Mueller MJ, Jakob T, Behrendt H.

J Exp Med. 2005 Feb 21;201(4):627-36. Erratum in: J Exp Med. 2005 Apr 18;201(8):1347.

33.

Phagocytosis-induced apoptosis in macrophages is mediated by up-regulation and activation of the Bcl-2 homology domain 3-only protein Bim.

Kirschnek S, Ying S, Fischer SF, Häcker H, Villunger A, Hochrein H, Häcker G.

J Immunol. 2005 Jan 15;174(2):671-9.

34.

Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways.

Hochrein H, Schlatter B, O'Keeffe M, Wagner C, Schmitz F, Schiemann M, Bauer S, Suter M, Wagner H.

Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11416-21. Epub 2004 Jul 22.

35.

The major surface protein of Wolbachia endosymbionts in filarial nematodes elicits immune responses through TLR2 and TLR4.

Brattig NW, Bazzocchi C, Kirschning CJ, Reiling N, Büttner DW, Ceciliani F, Geisinger F, Hochrein H, Ernst M, Wagner H, Bandi C, Hoerauf A.

J Immunol. 2004 Jul 1;173(1):437-45.

36.

Of men, mice and pigs: looking at their plasmacytoid dendritic cells [corrected].

Hochrein H, Wagner H.

Immunology. 2004 May;112(1):26-7. No abstract available.

37.

A regulatory role for CD37 in T cell proliferation.

van Spriel AB, Puls KL, Sofi M, Pouniotis D, Hochrein H, Orinska Z, Knobeloch KP, Plebanski M, Wright MD.

J Immunol. 2004 Mar 1;172(5):2953-61.

38.

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.

Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S.

Science. 2004 Mar 5;303(5663):1526-9. Epub 2004 Feb 19.

39.

Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice.

Spies B, Hochrein H, Vabulas M, Huster K, Busch DH, Schmitz F, Heit A, Wagner H.

J Immunol. 2003 Dec 1;171(11):5908-12.

40.

The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily.

Heil F, Ahmad-Nejad P, Hemmi H, Hochrein H, Ampenberger F, Gellert T, Dietrich H, Lipford G, Takeda K, Akira S, Wagner H, Bauer S.

Eur J Immunol. 2003 Nov;33(11):2987-97.

41.
42.

Human and mouse plasmacytoid dendritic cells.

Hochrein H, O'Keeffe M, Wagner H.

Hum Immunol. 2002 Dec;63(12):1103-10. Review.

PMID:
12480253
43.

Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus.

O'Keeffe M, Hochrein H, Vremec D, Caminschi I, Miller JL, Anders EM, Wu L, Lahoud MH, Henri S, Scott B, Hertzog P, Tatarczuch L, Shortman K.

J Exp Med. 2002 Nov 18;196(10):1307-19.

44.

Dendritic cell precursor populations of mouse blood: identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors.

O'Keeffe M, Hochrein H, Vremec D, Scott B, Hertzog P, Tatarczuch L, Shortman K.

Blood. 2003 Feb 15;101(4):1453-9. Epub 2002 Oct 10. Erratum in: Blood. 2003 May 1;101(9):3364.

PMID:
12393665
45.

CpG-DNA aided cross-presentation of soluble antigens by dendritic cells.

Maurer T, Heit A, Hochrein H, Ampenberger F, O'Keeffe M, Bauer S, Lipford GB, Vabulas RM, Wagner H.

Eur J Immunol. 2002 Aug;32(8):2356-64.

46.

Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets.

Luft T, Jefford M, Luetjens P, Toy T, Hochrein H, Masterman KA, Maliszewski C, Shortman K, Cebon J, Maraskovsky E.

Blood. 2002 Aug 15;100(4):1362-72.

PMID:
12149219
47.

Hierarchy of susceptibility of dendritic cell subsets to infection by Leishmania major: inverse relationship to interleukin-12 production.

Henri S, Curtis J, Hochrein H, Vremec D, Shortman K, Handman E.

Infect Immun. 2002 Jul;70(7):3874-80.

48.

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival.

Butzkueven H, Zhang JG, Soilu-Hanninen M, Hochrein H, Chionh F, Shipham KA, Emery B, Turnley AM, Petratos S, Ernst M, Bartlett PF, Kilpatrick TJ.

Nat Med. 2002 Jun;8(6):613-9.

PMID:
12042813
49.

IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells.

Luft T, Luetjens P, Hochrein H, Toy T, Masterman KA, Rizkalla M, Maliszewski C, Shortman K, Cebon J, Maraskovsky E.

Int Immunol. 2002 Apr;14(4):367-80.

PMID:
11934873
50.

Supplemental Content

Loading ...
Support Center