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Items: 1 to 50 of 267

1.

Downregulation of PKM2 decreases FASN expression in bladder cancer cells through AKT/mTOR/SREBP-1c axis.

Tao T, Su Q, Xu S, Deng J, Zhou S, Zhuang Y, Huang Y, He C, He S, Peng M, Hocher B, Yang X.

J Cell Physiol. 2018 Sep 17. doi: 10.1002/jcp.27129. [Epub ahead of print]

PMID:
30221356
2.

Epigenetics of recurrent pregnancy loss.

Hocher B, Hocher CF.

EBioMedicine. 2018 Aug 30. pii: S2352-3964(18)30339-6. doi: 10.1016/j.ebiom.2018.08.046. [Epub ahead of print] No abstract available.

3.

Lipopolysaccharides (LPS) Induced Angiogenesis During Chicken Embryogenesis is Abolished by Combined ETA/ETB Receptor Blockade.

Wang G, Li PZ, Zhang SY, Zhong S, Chu C, Zeng S, Yan Y, Cheng X, Chuai M, Hocher B, Yang X.

Cell Physiol Biochem. 2018;48(5):2084-2090. doi: 10.1159/000492547. Epub 2018 Aug 10.

4.

Bioinformatic identification of key genes and analysis of prognostic values in clear cell renal cell carcinoma.

Luo T, Chen X, Zeng S, Guan B, Hu B, Meng Y, Liu F, Wong T, Lu Y, Yun C, Hocher B, Yin L.

Oncol Lett. 2018 Aug;16(2):1747-1757. doi: 10.3892/ol.2018.8842. Epub 2018 May 30.

5.

AMP-activated kinase is a regulator of fibroblast growth factor 23 production.

Glosse P, Feger M, Mutig K, Chen H, Hirche F, Hasan AA, Gaballa MMS, Hocher B, Lang F, Föller M.

Kidney Int. 2018 Sep;94(3):491-501. doi: 10.1016/j.kint.2018.03.006. Epub 2018 May 31.

PMID:
29861059
6.

Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet.

Li J, Lu YP, Tsuprykov O, Hasan AA, Reichetzeder C, Tian M, Zhang XL, Zhang Q, Sun GY, Guo J, Gaballa MMS, Peng XN, Lin G, Hocher B.

Diabetologia. 2018 Aug;61(8):1862-1876. doi: 10.1007/s00125-018-4635-x. Epub 2018 May 18.

PMID:
29777263
7.

Insulin suppresses the production of fibroblast growth factor 23 (FGF23).

Bär L, Feger M, Fajol A, Klotz LO, Zeng S, Lang F, Hocher B, Föller M.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):5804-5809. doi: 10.1073/pnas.1800160115. Epub 2018 May 14.

PMID:
29760049
8.

Urinary cGMP predicts major adverse renal events in patients with mild renal impairment and/or diabetes mellitus before exposure to contrast medium.

Chaykovska L, Heunisch F, von Einem G, Hocher CF, Tsuprykov O, Pavkovic M, Sandner P, Kretschmer A, Chu C, Elitok S, Stasch JP, Hocher B.

PLoS One. 2018 Apr 12;13(4):e0195828. doi: 10.1371/journal.pone.0195828. eCollection 2018.

9.

High salt-induced excess reactive oxygen species production resulted in heart tube malformation during gastrulation.

Gao LR, Wang G, Zhang J, Li S, Chuai M, Bao Y, Hocher B, Yang X.

J Cell Physiol. 2018 Sep;233(9):7120-7133. doi: 10.1002/jcp.26528. Epub 2018 Mar 25.

PMID:
29574800
10.

Reference intervals for measured and calculated free 25-hydroxyvitamin D in normal pregnancy.

Tsuprykov O, Buse C, Skoblo R, Haq A, Hocher B.

J Steroid Biochem Mol Biol. 2018 Jul;181:80-87. doi: 10.1016/j.jsbmb.2018.03.005. Epub 2018 Mar 19.

PMID:
29567112
11.

Clear the Fog around Parathyroid Hormone Assays: What Do iPTH Assays Really Measure?

Hocher B, Zeng S.

Clin J Am Soc Nephrol. 2018 Apr 6;13(4):524-526. doi: 10.2215/CJN.01730218. Epub 2018 Mar 5. No abstract available.

PMID:
29507007
12.

Fetal Serum Metabolites Are Independently Associated with Gestational Diabetes Mellitus.

Lu YP, Reichetzeder C, Prehn C, von Websky K, Slowinski T, Chen YP, Yin LH, Kleuser B, Yang XS, Adamski J, Hocher B.

Cell Physiol Biochem. 2018;45(2):625-638. doi: 10.1159/000487119. Epub 2018 Jan 29.

13.

Cord Blood Lysophosphatidylcholine 16: 1 is Positively Associated with Birth Weight.

Lu YP, Reichetzeder C, Prehn C, Yin LH, Yun C, Zeng S, Chu C, Adamski J, Hocher B.

Cell Physiol Biochem. 2018;45(2):614-624. doi: 10.1159/000487118. Epub 2018 Jan 29.

14.

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics.

Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, Bradfield JP, Kreiner-Møller E, Huikari V, Metrustry S, Lunetta KL, Painter JN, Hottenga JJ, Allard C, Barton SJ, Espinosa A, Marsh JA, Potter C, Zhang G, Ang W, Berry DJ, Bouchard L, Das S; Early Growth Genetics (EGG) Consortium, Hakonarson H, Heikkinen J, Helgeland Ø, Hocher B, Hofman A, Inskip HM, Jones SE, Kogevinas M, Lind PA, Marullo L, Medland SE, Murray A, Murray JC, Njølstad PR, Nohr EA, Reichetzeder C, Ring SM, Ruth KS, Santa-Marina L, Scholtens DM, Sebert S, Sengpiel V, Tuke MA, Vaudel M, Weedon MN, Willemsen G, Wood AR, Yaghootkar H, Muglia LJ, Bartels M, Relton CL, Pennell CE, Chatzi L, Estivill X, Holloway JW, Boomsma DI, Montgomery GW, Murabito JM, Spector TD, Power C, Järvelin MR, Bisgaard H, Grant SFA, Sørensen TIA, Jaddoe VW, Jacobsson B, Melbye M, McCarthy MI, Hattersley AT, Hayes MG, Frayling TM, Hivert MF, Felix JF, Hyppönen E, Lowe WL Jr, Evans DM, Lawlor DA, Feenstra B, Freathy RM.

Hum Mol Genet. 2018 Feb 15;27(4):742-756. doi: 10.1093/hmg/ddx429.

15.

Why should we measure free 25(OH) vitamin D?

Tsuprykov O, Chen X, Hocher CF, Skoblo R, Lianghong Yin, Hocher B.

J Steroid Biochem Mol Biol. 2018 Jun;180:87-104. doi: 10.1016/j.jsbmb.2017.11.014. Epub 2017 Dec 5. Review.

PMID:
29217467
16.

Plasma ET-1 Concentrations Are Elevated in Pregnant Women with Hypertension -Meta-Analysis of Clinical Studies.

Lu YP, Hasan AA, Zeng S, Hocher B.

Kidney Blood Press Res. 2017;42(4):654-663. doi: 10.1159/000482004. Epub 2017 Nov 28.

17.

Impact of vitamin D on pregnancy-related disorders and on offspring outcome.

von Websky K, Hasan AA, Reichetzeder C, Tsuprykov O, Hocher B.

J Steroid Biochem Mol Biol. 2018 Jun;180:51-64. doi: 10.1016/j.jsbmb.2017.11.008. Epub 2017 Nov 21. Review.

PMID:
29169993
18.

DPP4 inhibition prevents AKI.

Reichetzeder C, Hocher B.

Oncotarget. 2017 Aug 12;8(39):64655-64656. doi: 10.18632/oncotarget.20212. eCollection 2017 Sep 12. No abstract available.

19.

Diabetic nephropathy: Renoprotective effects of GLP1R agonists and SGLT2 inhibitors.

Hocher B, Tsuprykov O.

Nat Rev Nephrol. 2017 Dec;13(12):728-730. doi: 10.1038/nrneph.2017.140. Epub 2017 Oct 9. No abstract available.

PMID:
28989173
20.

DNA methylation of the glucocorticoid receptor gene promoter in the placenta is associated with blood pressure regulation in human pregnancy.

Dwi Putra SE, Reichetzeder C, Meixner M, Liere K, Slowinski T, Hocher B.

J Hypertens. 2017 Nov;35(11):2276-2286. doi: 10.1097/HJH.0000000000001450.

PMID:
28817493
21.

Need for better PTH assays for clinical research and patient treatment.

Hocher B, Zeng S.

Clin Chem Lab Med. 2018 Jan 26;56(2):183-185. doi: 10.1515/cclm-2017-0617. No abstract available.

22.

Hope for CKD-MBD Patients: New Diagnostic Approaches for Better Treatment of CKD-MBD.

Hocher B, Pasch A.

Kidney Dis (Basel). 2017 Jul;3(1):8-14. doi: 10.1159/000477244. Epub 2017 Jun 16. Review.

23.

Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: the randomized MARLINA-T2D trial.

Groop PH, Cooper ME, Perkovic V, Hocher B, Kanasaki K, Haneda M, Schernthaner G, Sharma K, Stanton RC, Toto R, Cescutti J, Gordat M, Meinicke T, Koitka-Weber A, Thiemann S, von Eynatten M.

Diabetes Obes Metab. 2017 Nov;19(11):1610-1619. doi: 10.1111/dom.13041. Epub 2017 Jul 31.

24.

Resistant Starch Regulates Gut Microbiota: Structure, Biochemistry and Cell Signalling.

Yang X, Darko KO, Huang Y, He C, Yang H, He S, Li J, Li J, Hocher B, Yin Y.

Cell Physiol Biochem. 2017;42(1):306-318. doi: 10.1159/000477386. Epub 2017 May 25. Review.

25.

Plasma ET-1 Concentrations are Elevated in Patients with Hypertension - Meta-Analysis of Clinical Studies.

Xu M, Lu YP, Hasan AA, Hocher B.

Kidney Blood Press Res. 2017;42(2):304-313. doi: 10.1159/000477572. Epub 2017 May 26.

26.

Pre-Interventional Kynurenine Predicts Medium-Term Outcome after Contrast Media Exposure Due to Coronary Angiography.

Reichetzeder C, Heunisch F, Einem GV, Tsuprykov O, Kellner KH, Dschietzig T, Kretschmer A, Hocher B.

Kidney Blood Press Res. 2017;42(2):244-256. doi: 10.1159/000477222. Epub 2017 May 25.

27.

A Systematic Review and Meta-Analysis of Influenza A Virus Infection During Pregnancy Associated with an Increased Risk for Stillbirth and Low Birth Weight.

He J, Liu ZW, Lu YP, Li TY, Liang XJ, Arck PC, Huang SM, Hocher B, Chen YP.

Kidney Blood Press Res. 2017;42(2):232-243. doi: 10.1159/000477221. Epub 2017 May 15. Review.

28.

Head-to-head comparison of structurally unrelated dipeptidyl peptidase 4 inhibitors in the setting of renal ischemia reperfusion injury.

Reichetzeder C, von Websky K, Tsuprykov O, Mohagheghi Samarin A, Falke LG, Dwi Putra SE, Hasan AA, Antonenko V, Curato C, Rippmann J, Klein T, Hocher B.

Br J Pharmacol. 2017 Jul;174(14):2273-2286. doi: 10.1111/bph.13822. Epub 2017 Jun 7.

29.

Role of soluble and membrane-bound dipeptidyl peptidase-4 in diabetic nephropathy.

Hasan AA, Hocher B.

J Mol Endocrinol. 2017 Jul;59(1):R1-R10. doi: 10.1530/JME-17-0005. Epub 2017 Apr 18. Review.

PMID:
28420715
30.

Metabolomics for clinical use and research in chronic kidney disease.

Hocher B, Adamski J.

Nat Rev Nephrol. 2017 May;13(5):269-284. doi: 10.1038/nrneph.2017.30. Epub 2017 Mar 6. Review.

PMID:
28262773
31.

Why Current PTH Assays Mislead Clinical Decision Making in Patients with Secondary Hyperparathyroidism.

Hocher B, Yin L.

Nephron. 2017;136(2):137-142. doi: 10.1159/000455289. Epub 2017 Feb 10.

32.

ADMA predicts major adverse renal events in patients with mild renal impairment and/or diabetes mellitus undergoing coronary angiography.

Heunisch F, Chaykovska L, von Einem G, Alter M, Dschietzig T, Kretschmer A, Kellner KH, Hocher B.

Medicine (Baltimore). 2017 Feb;96(6):e6065. doi: 10.1097/MD.0000000000006065.

33.

Global Overexpression of ET-1 Decreases Blood Pressure - A Systematic Review and Meta-Analysis of ET-1 Transgenic Mice.

Lu YP, Tsuprykov O, Vignon-Zellweger N, Heiden S, Hocher B.

Kidney Blood Press Res. 2016;41(6):770-780. doi: 10.1159/000450567. Epub 2016 Nov 11. Review.

34.

Pharmacokinetic and Pharmacodynamic Characteristics of Subcutaneously Applied PTH-1-37.

Forssmann WG, Tillmann HC, Hock D, Forssmann K, Bernasconi C, Forssmann U, Richter R, Hocher B, Pfützner A.

Kidney Blood Press Res. 2016;41(5):507-518. Epub 2016 Aug 4.

35.

Developmental Origins of Disease - Crisis Precipitates Change.

Reichetzeder C, Dwi Putra SE, Li J, Hocher B.

Cell Physiol Biochem. 2016;39(3):919-38. doi: 10.1159/000447801. Epub 2016 Aug 12. Review.

36.

Increased global placental DNA methylation levels are associated with gestational diabetes.

Reichetzeder C, Dwi Putra SE, Pfab T, Slowinski T, Neuber C, Kleuser B, Hocher B.

Clin Epigenetics. 2016 Jul 26;8:82. doi: 10.1186/s13148-016-0247-9. eCollection 2016.

37.

Paternal programming of offspring cardiometabolic diseases in later life.

Li J, Tsuprykov O, Yang X, Hocher B.

J Hypertens. 2016 Nov;34(11):2111-26. doi: 10.1097/HJH.0000000000001051. Review.

38.

Maternal eNOS deficiency determines a fatty liver phenotype of the offspring in a sex dependent manner.

Hocher B, Haumann H, Rahnenführer J, Reichetzeder C, Kalk P, Pfab T, Tsuprykov O, Winter S, Hofmann U, Li J, Püschel GP, Lang F, Schuppan D, Schwab M, Schaeffeler E.

Epigenetics. 2016 Jul 2;11(7):539-52. doi: 10.1080/15592294.2016.1184800. Epub 2016 May 13.

39.

Maternal PCaaC38:6 is Associated With Preterm Birth - a Risk Factor for Early and Late Adverse Outcome of the Offspring.

Li J, Lu YP, Reichetzeder C, Kalk P, Kleuser B, Adamski J, Hocher B.

Kidney Blood Press Res. 2016;41(3):250-7. doi: 10.1159/000443428. Epub 2016 Apr 22.

40.

The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy.

Tsuprykov O, Ando R, Reichetzeder C, von Websky K, Antonenko V, Sharkovska Y, Chaykovska L, Rahnenführer J, Hasan AA, Tammen H, Alter M, Klein T, Ueda S, Yamagishi SI, Okuda S, Hocher B.

Kidney Int. 2016 May;89(5):1049-1061. doi: 10.1016/j.kint.2016.01.016. Epub 2016 Mar 24.

41.

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight.

Tyrrell J, Richmond RC, Palmer TM, Feenstra B, Rangarajan J, Metrustry S, Cavadino A, Paternoster L, Armstrong LL, De Silva NM, Wood AR, Horikoshi M, Geller F, Myhre R, Bradfield JP, Kreiner-Møller E, Huikari V, Painter JN, Hottenga JJ, Allard C, Berry DJ, Bouchard L, Das S, Evans DM, Hakonarson H, Hayes MG, Heikkinen J, Hofman A, Knight B, Lind PA, McCarthy MI, McMahon G, Medland SE, Melbye M, Morris AP, Nodzenski M, Reichetzeder C, Ring SM, Sebert S, Sengpiel V, Sørensen TI, Willemsen G, de Geus EJ, Martin NG, Spector TD, Power C, Järvelin MR, Bisgaard H, Grant SF, Nohr EA, Jaddoe VW, Jacobsson B, Murray JC, Hocher B, Hattersley AT, Scholtens DM, Davey Smith G, Hivert MF, Felix JF, Hyppönen E, Lowe WL Jr, Frayling TM, Lawlor DA, Freathy RM; Early Growth Genetics (EGG) Consortium.

JAMA. 2016 Mar 15;315(11):1129-40. doi: 10.1001/jama.2016.1975. Erratum in: JAMA. 2016 Apr 19;315(15):1661.

42.

Urinary Vitamin D Binding Protein and KIM-1 Are Potent New Biomarkers of Major Adverse Renal Events in Patients Undergoing Coronary Angiography.

Chaykovska L, Heunisch F, von Einem G, Alter ML, Hocher CF, Tsuprykov O, Dschietzig T, Kretschmer A, Hocher B.

PLoS One. 2016 Jan 11;11(1):e0145723. doi: 10.1371/journal.pone.0145723. eCollection 2016.

43.

Chronic Activation of Heme Free Guanylate Cyclase Leads to Renal Protection in Dahl Salt-Sensitive Rats.

Hoffmann LS, Kretschmer A, Lawrenz B, Hocher B, Stasch JP.

PLoS One. 2015 Dec 30;10(12):e0145048. doi: 10.1371/journal.pone.0145048. eCollection 2015.

44.

BMP4: a Possible Key Factor in Differentiation of Auditory Neuron-Like Cells from Bone-Derived Mesenchymal Stromal Cells.

Peng T, Zhu G, Dong Y, Zeng J, Li W, Guo W, Chen Y, Duan M, Hocher B, Xie D.

Clin Lab. 2015;61(9):1171-8.

45.

Endothelin-1 Overexpression Improves Renal Function in eNOS Knockout Mice.

Tsuprykov O, Chaykovska L, Kretschmer A, Stasch JP, Pfab T, Krause-Relle K, Reichetzeder C, Kalk P, Adamski J, Hocher B.

Cell Physiol Biochem. 2015;37(4):1474-90. doi: 10.1159/000438516. Epub 2015 Oct 29.

46.

The impact of high-salt exposure on cardiovascular development in the early chick embryo.

Wang G, Zhang N, Wei YF, Jin YM, Zhang SY, Cheng X, Ma ZL, Zhao SZ, Chen YP, Chuai M, Hocher B, Yang X.

J Exp Biol. 2015 Nov;218(Pt 21):3468-77. doi: 10.1242/jeb.129486. Epub 2015 Sep 7.

47.

The matrix metalloproteinases 2 and 9 initiate uraemic vascular calcifications.

Hecht E, Freise C, Websky KV, Nasser H, Kretzschmar N, Stawowy P, Hocher B, Querfeld U.

Nephrol Dial Transplant. 2016 May;31(5):789-97. doi: 10.1093/ndt/gfv321. Epub 2015 Sep 1.

PMID:
26333546
48.

Targeted activation of endothelin-1 exacerbates hypoxia-induced pulmonary hypertension.

Satwiko MG, Ikeda K, Nakayama K, Yagi K, Hocher B, Hirata K, Emoto N.

Biochem Biophys Res Commun. 2015 Sep 25;465(3):356-62. doi: 10.1016/j.bbrc.2015.08.002. Epub 2015 Aug 12.

PMID:
26275708
49.

Dipeptidyl peptidase-4 inhibition with linagliptin and effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: Rationale and design of the MARLINA-T2D™ trial.

Groop PH, Cooper ME, Perkovic V, Sharma K, Schernthaner G, Haneda M, Hocher B, Gordat M, Cescutti J, Woerle HJ, von Eynatten M.

Diab Vasc Dis Res. 2015 Nov;12(6):455-62. doi: 10.1177/1479164115579002. Epub 2015 Jul 28.

PMID:
26224765
50.

Endothelin and tubulointerstitial renal disease.

Ong AC, von Websky K, Hocher B.

Semin Nephrol. 2015 Mar;35(2):197-207. doi: 10.1016/j.semnephrol.2015.03.004. Review.

PMID:
25966351

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