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Items: 1 to 50 of 106

1.

Synthesis of benzoylbenzamide derivatives of 17α-E-vinyl estradiol and evaluation as ligands for the estrogen receptor-α ligand binding domain.

Hanson RN, McCaskill E, Hua E, Tongcharoensirikul P, Dilis R, Silver JL, Coulther TA, Ondrechen MJ, Labaree D, Hochberg RB.

Steroids. 2019 Apr;144:15-20. doi: 10.1016/j.steroids.2019.02.003. Epub 2019 Feb 6.

PMID:
30738075
2.

In vitro Autoradiographic Analysis of Regional Changes in Estrogen Receptor Alpha in the Brains of Cycling Female Rats.

Bowlby DA, Brown TJ, Hochberg RB, MacLusky NJ.

Neuroendocrinology. 2016;103(5):538-51. doi: 10.1159/000441077. Epub 2015 Oct 1.

PMID:
26422138
3.

Convergent synthesis of a steroidal antiestrogen-mitomycin C hybrid using "click" chemistry.

Hanson RN, Hua E, Labaree D, Hochberg RB, Proffitt K, Essigmann JM, Croy RG.

Org Biomol Chem. 2012 Nov 14;10(42):8501-8. doi: 10.1039/c2ob25902h. Epub 2012 Sep 25.

4.

Synthesis and evaluation of 4-(substituted styryl/alkenyl)-3,5-bis(4-hydroxyphenyl)-isoxazoles as ligands for the estrogen receptor.

Haddad T, Gershman R, Dilis R, Labaree D, Hochberg RB, Hanson RN.

Bioorg Med Chem Lett. 2012 Sep 15;22(18):5999-6003. doi: 10.1016/j.bmcl.2012.06.097. Epub 2012 Jul 15.

5.

Synthesis and evaluation of 11β-(4-substituted phenyl) estradiol analogs: transition from estrogen receptor agonists to antagonists.

Hanson RN, Hua E, Hendricks JA, Labaree D, Hochberg RB.

Bioorg Med Chem. 2012 Jun 15;20(12):3768-80. doi: 10.1016/j.bmc.2012.04.041. Epub 2012 May 7.

6.

Targeting the estrogen receptor with metal-carbonyl derivatives of estradiol.

Hanson RN, Kirss R, McCaskill E, Hua E, Tongcharoensirikul P, Olmsted SL, Labaree D, Hochberg RB.

Bioorg Med Chem Lett. 2012 Feb 15;22(4):1670-3. doi: 10.1016/j.bmcl.2011.12.111. Epub 2012 Jan 8.

7.

Synthesis and evaluation of 17α-(dimethylphenyl)vinyl estradiols as probes of the estrogen receptor-α ligand binding domain.

Hanson RN, McCaskill E, Tongcharoensirikul P, Dilis R, Labaree D, Hochberg RB.

Steroids. 2012 Apr;77(5):471-6. doi: 10.1016/j.steroids.2012.01.003. Epub 2012 Jan 17.

8.

Synthesis and evaluation of 17α-E-20-(heteroaryl)norpregn-1,3,5(10),20 tetraene-3,17β-diols [17α-(heteroaryl)vinyl estradiols] as ligands for the estrogen receptor-α ligand binding domain (ERα-LBD).

Olmsted SL, Tongcharoensirikul P, McCaskill E, Gandiaga K, Labaree D, Hochberg RB, Hanson RN.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):977-9. doi: 10.1016/j.bmcl.2011.12.003. Epub 2011 Dec 8.

9.

Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha.

Grasfeder LL, Gaillard S, Hammes SR, Ilkayeva O, Newgard CB, Hochberg RB, Dwyer MA, Chang CY, McDonnell DP.

Mol Endocrinol. 2009 Aug;23(8):1171-82. doi: 10.1210/me.2009-0024. Epub 2009 Apr 23.

10.

NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses.

Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachmiak A, Greene GL.

Nat Chem Biol. 2008 Apr;4(4):241-7. doi: 10.1038/nchembio.76. Epub 2008 Mar 16. Erratum in: Nat Chem Biol. 2008 Jun;4(6):379.

11.

3-ketosteroid reductase activity and expression by fetal rat osteoblasts.

McCarthy TL, Hochberg RB, Labaree DC, Centrella M.

J Biol Chem. 2007 Nov 23;282(47):34003-12. Epub 2007 Sep 28.

12.

International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors.

Lu NZ, Wardell SE, Burnstein KL, Defranco D, Fuller PJ, Giguere V, Hochberg RB, McKay L, Renoir JM, Weigel NL, Wilson EM, McDonnell DP, Cidlowski JA.

Pharmacol Rev. 2006 Dec;58(4):782-97. Review. No abstract available.

PMID:
17132855
13.

Microwave-enhanced nucleophilic fluorination in the synthesis of fluoropyridyl derivatives of [3,2-c]pyrazolo-corticosteroids, potential glucocorticoid receptor-mediated imaging agents.

Kahn MG, Konde E, Dossou F, Labaree DC, Hochberg RB, Hoyte RM.

Bioorg Med Chem Lett. 2006 Jul 1;16(13):3454-8. Epub 2006 Apr 27.

PMID:
16644222
14.

Nonpolar and short side chain groups at C-11beta of estradiol result in antiestrogens.

Zhang JX, Labaree DC, Hochberg RB.

J Med Chem. 2005 Mar 10;48(5):1428-47.

PMID:
15743187
15.

Estrogen to antiestrogen with a single methylene group resulting in an unusual steroidal selective estrogen receptor modulator.

Zhang JX, Labaree DC, Mor G, Hochberg RB.

J Clin Endocrinol Metab. 2004 Jul;89(7):3527-35.

PMID:
15240642
16.

Estrogen bioassay of ginseng extract and ArginMax, a nutritional supplement for the enhancement of female sexual function.

Polan ML, Hochberg RB, Trant AS, Wuh HC.

J Womens Health (Larchmt). 2004 May;13(4):427-30.

PMID:
15186659
17.
18.

Estren (4-estren-3alpha,17beta-diol) is a prohormone that regulates both androgenic and estrogenic transcriptional effects through the androgen receptor.

Centrella M, McCarthy TL, Chang WZ, Labaree DC, Hochberg RB.

Mol Endocrinol. 2004 May;18(5):1120-30. Epub 2004 Feb 5.

PMID:
14764654
19.

Synthesis of the 7alpha-cyano-(17alpha,20E/Z)-[125I]iodovinyl-19-nortestosterones: potential radioligands for androgen and progesterone receptors.

Ali H, Rousseau J, Ahmed N, Guertin V, Hochberg RB, van Lier JE.

Steroids. 2003 Dec;68(14):1163-71.

PMID:
14643878
20.

Synthesis and evaluation of B-, C-, and D-ring-substituted estradiol carboxylic acid esters as locally active estrogens.

Labaree DC, Zhang JX, Harris HA, O'Connor C, Reynolds TY, Hochberg RB.

J Med Chem. 2003 May 8;46(10):1886-904.

PMID:
12723952
21.

Synthesis of halogen-substituted pyridyl and pyrimidyl derivatives of [3,2-c]pyrazolo corticosteroids: strategies for the development of glucocorticoid receptor mediated imaging agents.

Hoyte RM, Zhang JX, Lerum R, Oluyemi A, Persaud P, O'Connor C, Labaree DC, Hochberg RB.

J Med Chem. 2002 Nov 21;45(24):5397-405.

PMID:
12431067
22.

Estradiol-16alpha-carboxylic acid esters as locally active estrogens.

Labaree DC, Reynolds TY, Hochberg RB.

J Med Chem. 2001 May 24;44(11):1802-14.

PMID:
11356114
23.
24.

Regiospecific esterification of estrogens by lecithin:cholesterol acyltransferase.

Kanji SS, Kuohung W, Labaree DC, Hochberg RB.

J Clin Endocrinol Metab. 1999 Jul;84(7):2481-8.

PMID:
10404824
25.

7alpha-Iodo and 7alpha-fluoro steroids as androgen receptor-mediated imaging agents.

Labaree DC, Hoyte RM, Nazareth LV, Weigel NL, Hochberg RB.

J Med Chem. 1999 Jun 3;42(11):2021-34.

PMID:
10354410
26.

Iodinated and fluorinated steroid 2'-aryl-[3,2-c] pyrazoles as potential glucocorticoid receptor imaging agents.

Hoyte RM, Labaree DC, Fede JM, Harris C, Hochberg RB.

Steroids. 1998 Nov;63(11):595-602.

PMID:
9830686
27.

Biological esterification of steroids.

Hochberg RB.

Endocr Rev. 1998 Jun;19(3):331-48. Review. No abstract available.

PMID:
9626557
28.

Sex and the developing brain: suppression of neuronal estrogen sensitivity by developmental androgen exposure.

MacLusky NJ, Bowlby DA, Brown TJ, Peterson RE, Hochberg RB.

Neurochem Res. 1997 Nov;22(11):1395-414. Review.

PMID:
9355112
29.

A direct stereoselective synthesis of 7 beta-hydroxytestosterone.

Labaree D, Hoyte RM, Hochberg RB.

Steroids. 1997 Jun;62(6):482-6.

PMID:
9185296
30.

7 alpha-iodine-125-iodo-5 alpha-dihydrotestosterone: a radiolabeled ligand for the androgen receptor.

Labaree DC, Brown TJ, Hoyte RM, Hochberg RB.

J Nucl Med. 1997 Mar;38(3):402-9.

31.

Regulation of estrogen receptor concentrations in the rat brain: effects of sustained androgen and estrogen exposure.

Brown TJ, Scherz B, Hochberg RB, MacLusky NJ.

Neuroendocrinology. 1996 Jan;63(1):53-60.

PMID:
8839355
32.

Sexual differentiation of estrogen receptor concentrations in the rat brain: effects of neonatal testosterone exposure.

Kühnemann S, Brown TJ, Hochberg RB, MacLusky NJ.

Brain Res. 1995 Sep 11;691(1-2):229-34.

PMID:
8590058
33.

Origin of estradiol fatty acid esters in human ovarian follicular fluid.

Pahuja SL, Kim AH, Lee G, Hochberg RB.

Biol Reprod. 1995 Mar;52(3):625-30.

PMID:
7756456
34.

Long-lived testosterone esters in the rat.

Borg W, Shackleton CH, Pahuja SL, Hochberg RB.

Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1545-9.

35.

Distribution of occupied and unoccupied estrogen receptors in the rat brain: effects of physiological gonadal steroid exposure.

Yuan H, Bowlby DA, Brown TJ, Hochberg RB, MacLusky NJ.

Endocrinology. 1995 Jan;136(1):96-105.

PMID:
7828562
37.

Sex differences in the development of estrogen receptors in the rat brain.

Kühnemann S, Brown TJ, Hochberg RB, MacLusky NJ.

Horm Behav. 1994 Dec;28(4):483-91.

PMID:
7729817
38.
39.

Pubertal development of estrogen receptors in the rat brain.

Brown TJ, Hochberg RB, Naftolin F, MacLusky NJ.

Mol Cell Neurosci. 1994 Oct;5(5):475-83.

PMID:
7820371
41.

Synthesis and evaluation of 7 alpha-iodo-5 alpha-dihydrotestosterone as a potential radioligand for androgen receptor.

Hoyte RM, Borderon K, Bryson K, Allen R, Hochberg RB, Brown TJ.

J Med Chem. 1994 Apr 15;37(8):1224-30.

PMID:
8164266
42.

Rapid stimulation of rhodamine 123 efflux from multidrug-resistant KB cells by progesterone.

Jancis EM, Chen HX, Carbone R, Hochberg RB, Dannies PS.

Biochem Pharmacol. 1993 Nov 2;46(9):1613-9.

PMID:
7902090
43.

In vitro autoradiographic visualization of occupied estrogen receptors in the rat brain with an iodinated estrogen ligand.

Walters MJ, Brown TJ, Hochberg RB, MacLusky NJ.

J Histochem Cytochem. 1993 Sep;41(9):1279-90.

PMID:
8354873
44.
45.
46.

Aromatase and testosterone fatty acid esters: the search for a cryptic biosynthetic pathway to estradiol esters.

Larner JM, Pahuja SL, Brown VM, Hochberg RB.

Steroids. 1992 Oct;57(10):475-9.

PMID:
1455454
47.

Measurement of estradiol-17-fatty acid esters in human tissues.

Larner JM, Shackleton CH, Roitman E, Schwartz PE, Hochberg RB.

J Clin Endocrinol Metab. 1992 Jul;75(1):195-200.

PMID:
1619010
48.

Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain.

Toran-Allerand CD, Miranda RC, Bentham WD, Sohrabji F, Brown TJ, Hochberg RB, MacLusky NJ.

Proc Natl Acad Sci U S A. 1992 May 15;89(10):4668-72.

50.

Intrinsic estrogenicity of some progestagenic drugs.

Markiewicz L, Hochberg RB, Gurpide E.

J Steroid Biochem Mol Biol. 1992 Jan;41(1):53-8.

PMID:
1734936

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