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Items: 11


Predicting and Experimentally Validating Hot-Spot Residues at Protein-Protein Interfaces.

Ibarra AA, Bartlett GJ, Hegedüs Z, Dutt S, Hobor F, Horner KA, Hetherington K, Spence K, Nelson A, Edwards TA, Woolfson DN, Sessions RB, Wilson AJ.

ACS Chem Biol. 2019 Oct 18;14(10):2252-2263. doi: 10.1021/acschembio.9b00560. Epub 2019 Sep 27.


IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.

Dagil R, Ball NJ, Ogrodowicz RW, Hobor F, Purkiss AG, Kelly G, Martin SR, Taylor IA, Ramos A.

Nucleic Acids Res. 2019 May 7;47(8):4334-4348. doi: 10.1093/nar/gkz136.


The structure of the RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sites.

Mittal A, Hobor F, Zhang Y, Martin SR, Gamblin SJ, Ramos A, Wilson JR.

Nucleic Acids Res. 2018 Apr 20;46(7):3802-3812. doi: 10.1093/nar/gky199.


A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.

Hobor F, Dallmann A, Ball NJ, Cicchini C, Battistelli C, Ogrodowicz RW, Christodoulou E, Martin SR, Castello A, Tripodi M, Taylor IA, Ramos A.

Nat Commun. 2018 Feb 26;9(1):831. doi: 10.1038/s41467-018-03182-3.


Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively.

Nowak JS, Hobor F, Downie Ruiz Velasco A, Choudhury NR, Heikel G, Kerr A, Ramos A, Michlewski G.

RNA. 2017 Mar;23(3):317-332. doi: 10.1261/rna.059196.116. Epub 2016 Nov 23.


Recognition of asymmetrically dimethylated arginine by TDRD3.

Sikorsky T, Hobor F, Krizanova E, Pasulka J, Kubicek K, Stefl R.

Nucleic Acids Res. 2012 Dec;40(22):11748-55. doi: 10.1093/nar/gks929. Epub 2012 Oct 12.


In vivo SELEX reveals novel sequence and structural determinants of Nrd1-Nab3-Sen1-dependent transcription termination.

Porrua O, Hobor F, Boulay J, Kubicek K, D'Aubenton-Carafa Y, Gudipati RK, Stefl R, Libri D.

EMBO J. 2012 Oct 3;31(19):3935-48. doi: 10.1038/emboj.2012.237. Epub 2012 Aug 28.


Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation.

Holub P, Lalakova J, Cerna H, Pasulka J, Sarazova M, Hrazdilova K, Arce MS, Hobor F, Stefl R, Vanacova S.

Nucleic Acids Res. 2012 Jul;40(12):5679-93. doi: 10.1093/nar/gks223. Epub 2012 Mar 8.


Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein.

Hobor F, Pergoli R, Kubicek K, Hrossova D, Bacikova V, Zimmermann M, Pasulka J, Hofr C, Vanacova S, Stefl R.

J Biol Chem. 2011 Feb 4;286(5):3645-57. doi: 10.1074/jbc.M110.158774. Epub 2010 Nov 17.


1H, 13C, and 15N chemical shift assignments for the RNA recognition motif of Nab3.

Pergoli R, Kubicek K, Hobor F, Pasulka J, Stefl R.

Biomol NMR Assign. 2010 Apr;4(1):119-21. doi: 10.1007/s12104-010-9221-1. Epub 2010 Mar 23.


An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins.

Brown JH, Yang Y, Reshetnikova L, Gourinath S, Süveges D, Kardos J, Hóbor F, Reutzel R, Nyitray L, Cohen C.

J Mol Biol. 2008 Feb 1;375(5):1434-43. Epub 2007 Nov 28.

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