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Items: 14


Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline.

Artzy-Schnirman A, Hobi N, Schneider-Daum N, Guenat OT, Lehr CM, Sznitman J.

Eur J Pharm Biopharm. 2019 Nov;144:11-17. doi: 10.1016/j.ejpb.2019.09.006. Epub 2019 Sep 6. Review.


Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549.

Tièche CC, Gao Y, Bührer ED, Hobi N, Berezowska SA, Wyler K, Froment L, Weis S, Peng RW, Bruggmann R, Schär P, Amrein MA, Hall SRR, Dorn P, Kocher G, Riether C, Ochsenbein A, Schmid RA, Marti TM.

Neoplasia. 2019 Feb;21(2):185-196. doi: 10.1016/j.neo.2018.09.008. Epub 2018 Dec 27.


Medium throughput breathing human primary cell alveolus-on-chip model.

Stucki JD, Hobi N, Galimov A, Stucki AO, Schneider-Daum N, Lehr CM, Huwer H, Frick M, Funke-Chambour M, Geiser T, Guenat OT.

Sci Rep. 2018 Sep 25;8(1):14359. doi: 10.1038/s41598-018-32523-x.


Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro.

Zeinali S, Bichsel CA, Hobi N, Funke M, Marti TM, Schmid RA, Guenat OT, Geiser T.

Angiogenesis. 2018 Nov;21(4):861-871. doi: 10.1007/s10456-018-9631-8. Epub 2018 Jul 2.


A small key unlocks a heavy door: The essential function of the small hydrophobic proteins SP-B and SP-C to trigger adsorption of pulmonary surfactant lamellar bodies.

Hobi N, Giolai M, Olmeda B, Miklavc P, Felder E, Walther P, Dietl P, Frick M, Pérez-Gil J, Haller T.

Biochim Biophys Acta. 2016 Aug;1863(8):2124-34. doi: 10.1016/j.bbamcr.2016.04.028. Epub 2016 May 4.


A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca²⁺ release from acidic Ca²⁺ stores.

Fois G, Hobi N, Felder E, Ziegler A, Miklavc P, Walther P, Radermacher P, Haller T, Dietl P.

Cell Calcium. 2015 Dec;58(6):628-37. doi: 10.1016/j.ceca.2015.10.002. Epub 2015 Oct 27.


Physiological variables affecting surface film formation by native lamellar body-like pulmonary surfactant particles.

Hobi N, Siber G, Bouzas V, Ravasio A, Pérez-Gil J, Haller T.

Biochim Biophys Acta. 2014 Jul;1838(7):1842-50. doi: 10.1016/j.bbamem.2014.02.015. Epub 2014 Feb 27.


Surfactant secretion in LRRK2 knock-out rats: changes in lamellar body morphology and rate of exocytosis.

Miklavc P, Ehinger K, Thompson KE, Hobi N, Shimshek DR, Frick M.

PLoS One. 2014 Jan 21;9(1):e84926. doi: 10.1371/journal.pone.0084926. eCollection 2014.


Nontoxic impact of PEG-coated gold nanospheres on functional pulmonary surfactant-secreting alveolar type II cells.

Bouzas V, Haller T, Hobi N, Felder E, Pastoriza-Santos I, Pérez-Gil J.

Nanotoxicology. 2014 Dec;8(8):813-23. doi: 10.3109/17435390.2013.829878. Epub 2013 Aug 27.


Fusion-activated cation entry (FACE) via P2X₄ couples surfactant secretion and alveolar fluid transport.

Thompson KE, Korbmacher JP, Hecht E, Hobi N, Wittekindt OH, Dietl P, Kranz C, Frick M.

FASEB J. 2013 Apr;27(4):1772-83. doi: 10.1096/fj.12-220533. Epub 2013 Jan 10.


Interfacial stress affects rat alveolar type II cell signaling and gene expression.

Hobi N, Ravasio A, Haller T.

Am J Physiol Lung Cell Mol Physiol. 2012 Jul;303(2):L117-29. doi: 10.1152/ajplung.00340.2011. Epub 2012 May 18.


Actin coating and compression of fused secretory vesicles are essential for surfactant secretion--a role for Rho, formins and myosin II.

Miklavc P, Hecht E, Hobi N, Wittekindt OH, Dietl P, Kranz C, Frick M.

J Cell Sci. 2012 Jun 1;125(Pt 11):2765-74. doi: 10.1242/jcs.105262. Epub 2012 Mar 16.


Interfacial sensing by alveolar type II cells: a new concept in lung physiology?

Ravasio A, Hobi N, Bertocchi C, Jesacher A, Dietl P, Haller T.

Am J Physiol Cell Physiol. 2011 Jun;300(6):C1456-65. doi: 10.1152/ajpcell.00427.2010. Epub 2011 Jan 26.


Effects of perfluorocarbons on surfactant exocytosis and membrane properties in isolated alveolar type II cells.

Wemhöner A, Hackspiel I, Hobi N, Ravasio A, Haller T, Rüdiger M.

Respir Res. 2010 May 9;11:52. doi: 10.1186/1465-9921-11-52.

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