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Items: 29

1.

Dissecting mechanisms of resistance to targeted drug combination therapy in human colorectal cancer.

Clarke PA, Roe T, Swabey K, Hobbs SM, McAndrew C, Tomlin K, Westwood I, Burke R, van Montfort R, Workman P.

Oncogene. 2019 Jun;38(25):5076-5090. doi: 10.1038/s41388-019-0780-z. Epub 2019 Mar 25.

PMID:
30905967
2.

Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases.

Clarke PA, Ortiz-Ruiz MJ, TePoele R, Adeniji-Popoola O, Box G, Court W, Czasch S, El Bawab S, Esdar C, Ewan K, Gowan S, De Haven Brandon A, Hewitt P, Hobbs SM, Kaufmann W, Mallinger A, Raynaud F, Roe T, Rohdich F, Schiemann K, Simon S, Schneider R, Valenti M, Weigt S, Blagg J, Blaukat A, Dale TC, Eccles SA, Hecht S, Urbahns K, Workman P, Wienke D.

Elife. 2016 Dec 9;5. pii: e20722. doi: 10.7554/eLife.20722.

3.

In vitro and in vivo models for evaluation of GDEPT: quantifying bystander killing in cell cultures and tumors.

Wilson WR, Pullen SM, Hogg A, Hobbs SM, Pruijn FB, Hicks KO.

Methods Mol Med. 2004;90:403-31. No abstract available.

PMID:
14657576
4.

High levels of the MDM2 oncogene in paediatric rhabdomyosarcoma cell lines may confer multidrug resistance.

Cocker HA, Hobbs SM, Tiffin N, Pritchard-Jones K, Pinkerton CR, Kelland LR.

Br J Cancer. 2001 Nov 30;85(11):1746-52.

5.
6.

Effect of p53 status on sensitivity to platinum complexes in a human ovarian cancer cell line.

Pestell KE, Hobbs SM, Titley JC, Kelland LR, Walton MI.

Mol Pharmacol. 2000 Mar;57(3):503-11.

PMID:
10692490
7.

Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954).

Skelly JV, Sanderson MR, Suter DA, Baumann U, Read MA, Gregory DS, Bennett M, Hobbs SM, Neidle S.

J Med Chem. 1999 Oct 21;42(21):4325-30.

PMID:
10543876
8.

Expression of recombinant antibody fusion proteins in E. coli.

Hobbs SM.

Methods Mol Biol. 1998;80:419-25. No abstract available.

PMID:
9664398
9.

Investigation of alternative prodrugs for use with E. coli nitroreductase in 'suicide gene' approaches to cancer therapy.

Bailey SM, Knox RJ, Hobbs SM, Jenkins TC, Mauger AB, Melton RG, Burke PJ, Connors TA, Hart IR.

Gene Ther. 1996 Dec;3(12):1143-50.

PMID:
8986441
11.

IgA antibodies in the bile of rats. V. Primacy of the GALT as a source of IgA.

Gyure LA, Hall JG, Hobbs SM, Jackson LE.

Immunology. 1991 Jan;72(1):85-8.

12.

Low affinity antibodies against collagen type II are associated with pathology in collagen-induced arthritis in mice.

Staines NA, Ekong TA, Thompson HS, Isaacs AB, Loryman B, Major PJ, Hobbs SM, Devey ME.

J Autoimmun. 1990 Dec;3(6):643-57.

PMID:
2088389
13.

Some properties of dendritic macrophages from peripheral lymph.

Barfoot R, Denham S, Gyure LA, Hall JG, Hobbs SM, Jackson LE, Robertson D.

Immunology. 1989 Oct;68(2):233-9.

14.

Role of carbohydrate in binding of IgG to the Fc receptor of neonatal rat enterocytes.

Peppard JV, Hobbs SM, Jackson LE.

Mol Immunol. 1989 May;26(5):495-500.

PMID:
2770747
15.

Pharmacokinetic studies of radiolabelled rat monoclonal antibodies recognising syngeneic sarcoma antigens. I. Comparison of IgG subclasses.

Eccles SA, Purvies HP, Styles JM, Hobbs SM, Dean CJ.

Cancer Immunol Immunother. 1989;30(1):5-12.

PMID:
2598175
16.

Pharmacokinetic studies of radiolabelled rat monoclonal antibodies recognising syngeneic sarcoma antigens. II. Effect of host age and immune status.

Eccles SA, Purvies HP, Styles JM, Hobbs SM, Dean CJ.

Cancer Immunol Immunother. 1989;30(1):13-20.

PMID:
2598171
17.

Tolerogenic activity of polymerized type II collagen in preventing collagen-induced arthritis in rats.

Thompson HS, Henderson B, Spencer JM, Hobbs SM, Peppard JV, Staines NA.

Clin Exp Immunol. 1988 Apr;72(1):20-5.

18.
19.

Lymphotoxic activity of methyl prednisolone in vitro--I. Comparative toxicity of methyl prednisolone in human cell lines of B and T origin.

Millar BC, Bell JB, Hobbs SM, Jackson E, Hall JG.

Biochem Pharmacol. 1987 Mar 15;36(6):831-7.

PMID:
3032198
20.

The IgG Fc receptor from neonatal rat intestine: analysis of behaviour in detergent solution.

Hobbs SM, Jackson LE, Peppard JV.

Adv Exp Med Biol. 1987;216B:1163-8. No abstract available.

PMID:
2962469
21.

Biochemical characterization of chicken secretory component.

Peppard JV, Hobbs SM, Jackson LE, Rose ME, Mockett AP.

Eur J Immunol. 1986 Mar;16(3):225-9.

PMID:
3082648
23.

The production of hybridomas from the gut associated lymphoid tissue of tumour bearing rats. I. Mesenteric nodes as a source of IgG producing cells.

Dean CJ, Styles JM, Gyure LA, Peppard J, Hobbs SM, Jackson E, Hall JG.

Clin Exp Immunol. 1984 Aug;57(2):358-64.

24.

Coccidiosis: characterization of antibody responses to infection with Eimeria nieschulzi.

Rose ME, Peppard JV, Hobbs SM.

Parasite Immunol. 1984 Jan;6(1):1-12.

PMID:
6608083
25.
26.
27.

Production of IgA secreting hybridomas: a monoclonal rat antibody of the IgA class with specificity for RT1c.

Dean CJ, Gyure LA, Styles JM, Hobbs SM, North SM, Hall JG.

J Immunol Methods. 1982 Sep 30;53(3):307-12.

PMID:
7142711
28.

Syngeneic antitumour antibodies in rats: clearance of cell-bound antibody in vivo and in vitro.

Dean CJ, Hobbs SM, Hopkins JU, North SM, Styles JM.

Br J Cancer. 1982 Aug;46(2):190-7.

29.

Metastasis in the nude rat associated with lack of immune response.

Eccles SA, Styles JM, Hobbs SM, Dean CJ.

Br J Cancer. 1979 Nov;40(5):802-5. No abstract available.

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