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177Lu-labeled low-molecular-weight agents for PSMA-targeted radiopharmaceutical therapy.

Banerjee SR, Kumar V, Lisok A, Chen J, Minn I, Brummet M, Boinapally S, Cole M, Ngen E, Wharram B, Brayton C, Hobbs RF, Pomper MG.

Eur J Nucl Med Mol Imaging. 2019 Nov;46(12):2545-2557. doi: 10.1007/s00259-019-04434-0. Epub 2019 Aug 10.


68Ga-DOTATATE PET: temporal variation of maximum standardized uptake value in normal tissues and neuroendocrine tumours.

Coura-Filho GB, Hoff AAFO, Duarte PS, Buchpiguel CA, Josefsson A, Hobbs RF, Sgouros G, Sapienza MT.

Nucl Med Commun. 2019 Sep;40(9):920-926. doi: 10.1097/MNM.0000000000001048.


Preclinical evaluation of 203/212Pb-labeled low-molecular-weight compounds for targeted radiopharmaceutical therapy of prostate cancer.

Ray Banerjee S, Minn IL, Kumar V, Josefsson A, Lisok A, Brummet M, Chen J, Kiess A, Baidoo K, Brayton C, Mease RC, Brechbiel M, Sgouros G, Hobbs RF, Pomper MG.

J Nucl Med. 2019 Jun 28. pii: jnumed.119.229393. doi: 10.2967/jnumed.119.229393. [Epub ahead of print]


Opportunities and challenges of a novel cardiac output response to stress (CORS) test to enhance diagnosis of heart failure in primary care: qualitative study.

Charman S, Okwose N, Maniatopoulos G, Graziadio S, Metzler T, Banks H, Vale L, MacGowan GA, Seferović PM, Fuat A, Deaton C, Mant J, Hobbs RFD, Jakovljevic DG.

BMJ Open. 2019 Apr 14;9(4):e028122. doi: 10.1136/bmjopen-2018-028122.


Phase II study of intraoperative dosimetry for prostate brachytherapy using registered ultrasound and fluoroscopy.

Lee J, Hobbs RF, Zahurak M, Ng SK, Zhang Z, Burdette EC, DeWeese TL, Song DY.

Brachytherapy. 2018 Nov - Dec;17(6):858-865. doi: 10.1016/j.brachy.2018.07.013. Epub 2018 Sep 11.


A novel cardiac output response to stress test developed to improve diagnosis and monitoring of heart failure in primary care.

Charman SJ, Okwose NC, Stefanetti RJ, Bailey K, Skinner J, Ristic A, Seferovic PM, Scott M, Turley S, Fuat A, Mant J, Hobbs RFD, MacGowan GA, Jakovljevic DG.

ESC Heart Fail. 2018 Aug;5(4):703-712. doi: 10.1002/ehf2.12302. Epub 2018 Jun 26. Erratum in: ESC Heart Fail. 2019 Aug;6(4):898.


Combined model-based and patient-specific dosimetry for 18F-DCFPyL, a PSMA-targeted PET agent.

Plyku D, Mena E, Rowe SP, Lodge MA, Szabo Z, Cho SY, Pomper MG, Sgouros G, Hobbs RF.

Eur J Nucl Med Mol Imaging. 2018 Jun;45(6):989-998. doi: 10.1007/s00259-018-3939-x. Epub 2018 Feb 19.


Comparative Dosimetry for 68Ga-DOTATATE: Impact of Using Updated ICRP Phantoms, S Values, and Tissue-Weighting Factors.

Josefsson A, Hobbs RF, Ranka S, Schwarz BC, Plyku D, Willegaignon de Amorim de Carvalho J, Buchpiguel CA, Sapienza MT, Bolch WE, Sgouros G.

J Nucl Med. 2018 Aug;59(8):1281-1288. doi: 10.2967/jnumed.117.203893. Epub 2018 Feb 9.


Main messages for primary care from the 2016 European Guidelines on cardiovascular disease prevention in clinical practice.

Piepoli MF, Hoes AW, Brotons C, Hobbs RFD, Corra U; Task Force for the 2016 guidelines on cardiovascular disease prevention in clinical practice.

Eur J Gen Pract. 2018 Dec;24(1):51-56. doi: 10.1080/13814788.2017.1398320. Epub 2017 Nov 23.


Pharmacokinetics, microscale distribution, and dosimetry of alpha-emitter-labeled anti-PD-L1 antibodies in an immune competent transgenic breast cancer model.

Nedrow JR, Josefsson A, Park S, Bäck T, Hobbs RF, Brayton C, Bruchertseifer F, Morgenstern A, Sgouros G.

EJNMMI Res. 2017 Dec;7(1):57. doi: 10.1186/s13550-017-0303-2. Epub 2017 Jul 18.


Depth-dependent concentrations of hematopoietic stem cells in the adult skeleton: Implications for active marrow dosimetry.

Geyer AM, Schwarz BC, O'Reilly SE, Hobbs RF, Sgouros G, Bolch WE.

Med Phys. 2017 Feb;44(2):747-761. doi: 10.1002/mp.12056. Epub 2017 Jan 30.


Recombinant Human Thyroid-Stimulating Hormone Versus Thyroid Hormone Withdrawal in 124I PET/CT-Based Dosimetry for 131I Therapy of Metastatic Differentiated Thyroid Cancer.

Plyku D, Hobbs RF, Huang K, Atkins F, Garcia C, Sgouros G, Van Nostrand D.

J Nucl Med. 2017 Jul;58(7):1146-1154. doi: 10.2967/jnumed.116.179366. Epub 2017 Jan 19.


Quantitative impact of changes in marrow cellularity, skeletal size, and bone mineral density on active marrow dosimetry based upon a reference model.

Geyer AM, Schwarz BC, Hobbs RF, Sgouros G, Bolch WE.

Med Phys. 2017 Jan;44(1):272-283. doi: 10.1002/mp.12002.


Comparison of quantitative Y-90 SPECT and non-time-of-flight PET imaging in post-therapy radioembolization of liver cancer.

Yue J, Mauxion T, Reyes DK, Lodge MA, Hobbs RF, Rong X, Dong Y, Herman JM, Wahl RL, Geschwind JH, Frey EC.

Med Phys. 2016 Oct;43(10):5779.


(2S)-2-(3-(1-Carboxy-5-(4-211At-Astatobenzamido)Pentyl)Ureido)-Pentanedioic Acid for PSMA-Targeted α-Particle Radiopharmaceutical Therapy.

Kiess AP, Minn I, Vaidyanathan G, Hobbs RF, Josefsson A, Shen C, Brummet M, Chen Y, Choi J, Koumarianou E, Baidoo K, Brechbiel MW, Mease RC, Sgouros G, Zalutsky MR, Pomper MG.

J Nucl Med. 2016 Oct;57(10):1569-1575. Epub 2016 May 26.


Whole-Body and Microenvironmental Localization of Radium-223 in Naïve and Mouse Models of Prostate Cancer Metastasis.

Abou DS, Ulmert D, Doucet M, Hobbs RF, Riddle RC, Thorek DL.

J Natl Cancer Inst. 2015 Dec 18;108(5). pii: djv380. doi: 10.1093/jnci/djv380. Print 2016 May.


Strengths and Weaknesses of a Planar Whole-Body Method of (153)Sm Dosimetry for Patients with Metastatic Osteosarcoma and Comparison with Three-Dimensional Dosimetry.

Plyku D, Loeb DM, Prideaux AR, Baechler S, Wahl RL, Sgouros G, Hobbs RF.

Cancer Biother Radiopharm. 2015 Nov;30(9):369-79. doi: 10.1089/cbr.2014.1803.


Tumor and red bone marrow dosimetry: comparison of methods for prospective treatment planning in pretargeted radioimmunotherapy.

Woliner-van der Weg W, Schoffelen R, Hobbs RF, Gotthardt M, Goldenberg DM, Sharkey RM, Slump CH, van der Graaf WT, Oyen WJ, Boerman OC, Sgouros G, Visser EP.

EJNMMI Phys. 2015 Dec;2(1):5. doi: 10.1186/s40658-014-0104-x. Epub 2015 Feb 24.


Use of standardized uptake value thresholding for target volume delineation in pediatric Hodgkin lymphoma.

Walker AJ, Chirindel A, Hobbs RF, Huynh-Le MP, Moore JA, Cho SY, Terezakis SA.

Pract Radiat Oncol. 2015 Jul-Aug;5(4):219-27. doi: 10.1016/j.prro.2014.12.004.


Factors affecting the stability and repeatability of gamma camera calibration for quantitative imaging applications based on a retrospective review of clinical data.

Anizan N, Wang H, Zhou XC, Hobbs RF, Wahl RL, Frey EC.

EJNMMI Res. 2014 Dec;4(1):67. doi: 10.1186/s13550-014-0067-x. Epub 2014 Dec 16.


Preclinical evaluation of 86Y-labeled inhibitors of prostate-specific membrane antigen for dosimetry estimates.

Banerjee SR, Foss CA, Pullambhatla M, Wang Y, Srinivasan S, Hobbs RF, Baidoo KE, Brechbiel MW, Nimmagadda S, Mease RC, Sgouros G, Pomper MG.

J Nucl Med. 2015 Apr;56(4):628-34. doi: 10.2967/jnumed.114.149062. Epub 2015 Feb 26.


Randomised controlled feasibility trial of a web-based weight management intervention with nurse support for obese patients in primary care.

Yardley L, Ware LJ, Smith ER, Williams S, Bradbury KJ, Arden-Close EJ, Mullee MA, Moore MV, Peacock JL, Lean ME, Margetts BM, Byrne CD, Hobbs RF, Little P.

Int J Behav Nutr Phys Act. 2014 May 21;11:67. doi: 10.1186/1479-5868-11-67.


The role of preclinical models in radiopharmaceutical therapy.

Sgouros G, Hobbs RF, Abou DS.

Am Soc Clin Oncol Educ Book. 2014:e121-5. doi: 10.14694/EdBook_AM.2014.34.e121. Review.


Dosimetry for radiopharmaceutical therapy.

Sgouros G, Hobbs RF.

Semin Nucl Med. 2014 May;44(3):172-8. doi: 10.1053/j.semnuclmed.2014.03.007. Review.


Voxelized Dose--FDG-PET Response in HDR Brachytherapy of Rectal Cancer.

Hobbs RF, Le Y, Armour E, Efron J, Azad N, Diaz L, Wahl R, Sgouros G, Gearhardt S, Hermann J.

Pract Radiat Oncol. 2013 Apr-Jun;3(2 Suppl 1):S28-9. doi: 10.1016/j.prro.2013.01.097. Epub 2013 Mar 25. No abstract available.


Redefining relative biological effectiveness in the context of the EQDX formalism: implications for alpha-particle emitter therapy.

Hobbs RF, Howell RW, Song H, Baechler S, Sgouros G.

Radiat Res. 2014 Jan;181(1):90-8. doi: 10.1667/RR13483.1.


Redefining Relative Biological Effectiveness in the Context of the EQDX Formalism: Implications for Alpha-Particle Emitter Therapy.

Hobbs RF, Howell RW, Song H, Baechler S, Sgouros G.

Radiat Res. 2013 Dec 30. [Epub ahead of print]


Mapping patterns of local recurrence after pancreaticoduodenectomy for pancreatic adenocarcinoma: a new approach to adjuvant radiation field design.

Dholakia AS, Kumar R, Raman SP, Moore JA, Ellsworth S, McNutt T, Laheru DA, Jaffee E, Cameron JL, Tran PT, Hobbs RF, Wolfgang CL, Herman JM.

Int J Radiat Oncol Biol Phys. 2013 Dec 1;87(5):1007-15. doi: 10.1016/j.ijrobp.2013.09.005.


Use of the FLUKA Monte Carlo code for 3D patient-specific dosimetry on PET-CT and SPECT-CT images.

Botta F, Mairani A, Hobbs RF, Vergara Gil A, Pacilio M, Parodi K, Cremonesi M, Coca Pérez MA, Di Dia A, Ferrari M, Guerriero F, Battistoni G, Pedroli G, Paganelli G, Torres Aroche LA, Sgouros G.

Phys Med Biol. 2013 Nov 21;58(22):8099-120.


Radiobiologic optimization of combination radiopharmaceutical therapy applied to myeloablative treatment of non-Hodgkin lymphoma.

Hobbs RF, Wahl RL, Frey EC, Kasamon Y, Song H, Huang P, Jones RJ, Sgouros G.

J Nucl Med. 2013 Sep;54(9):1535-42. doi: 10.2967/jnumed.112.117952. Epub 2013 Aug 5.


Targeting aberrant DNA double-strand break repair in triple-negative breast cancer with alpha-particle emitter radiolabeled anti-EGFR antibody.

Song H, Hedayati M, Hobbs RF, Shao C, Bruchertseifer F, Morgenstern A, Deweese TL, Sgouros G.

Mol Cancer Ther. 2013 Oct;12(10):2043-54. doi: 10.1158/1535-7163.MCT-13-0108. Epub 2013 Jul 19.


Improved dose-volume histogram estimates for radiopharmaceutical therapy by optimizing quantitative SPECT reconstruction parameters.

Cheng L, Hobbs RF, Segars PW, Sgouros G, Frey EC.

Phys Med Biol. 2013 Jun 7;58(11):3631-47. doi: 10.1088/0031-9155/58/11/3631. Epub 2013 May 7.


Study of the impact of tissue density heterogeneities on 3-dimensional abdominal dosimetry: comparison between dose kernel convolution and direct Monte Carlo methods.

Dieudonné A, Hobbs RF, Lebtahi R, Maurel F, Baechler S, Wahl RL, Boubaker A, Le Guludec D, Sgouros G, Gardin I.

J Nucl Med. 2013 Feb;54(2):236-43. doi: 10.2967/jnumed.112.105825. Epub 2012 Dec 18.


Three-dimensional radiobiological dosimetry of kidneys for treatment planning in peptide receptor radionuclide therapy.

Baechler S, Hobbs RF, Boubaker A, Buchegger F, He B, Frey EC, Sgouros G.

Med Phys. 2012 Oct;39(10):6118-28. doi: 10.1118/1.4752213.


A nephron-based model of the kidneys for macro-to-micro α-particle dosimetry.

Hobbs RF, Song H, Huso DL, Sundel MH, Sgouros G.

Phys Med Biol. 2012 Jul 7;57(13):4403-24. doi: 10.1088/0031-9155/57/13/4403. Epub 2012 Jun 15.


A bone marrow toxicity model for ²²³Ra alpha-emitter radiopharmaceutical therapy.

Hobbs RF, Song H, Watchman CJ, Bolch WE, Aksnes AK, Ramdahl T, Flux GD, Sgouros G.

Phys Med Biol. 2012 May 21;57(10):3207-22. doi: 10.1088/0031-9155/57/10/3207. Epub 2012 May 1.


Tumor dosimetry and response for 153Sm-ethylenediamine tetramethylene phosphonic acid therapy of high-risk osteosarcoma.

Senthamizhchelvan S, Hobbs RF, Song H, Frey EC, Zhang Z, Armour E, Wahl RL, Loeb DM, Sgouros G.

J Nucl Med. 2012 Feb;53(2):215-24. doi: 10.2967/jnumed.111.096677. Epub 2012 Jan 17.


Modelling and dosimetry for alpha-particle therapy.

Sgouros G, Hobbs RF, Song H.

Curr Radiopharm. 2011 Jul;4(3):261-5. Review.


A model of cellular dosimetry for macroscopic tumors in radiopharmaceutical therapy.

Hobbs RF, Baechler S, Fu DX, Esaias C, Pomper MG, Ambinder RF, Sgouros G.

Med Phys. 2011 Jun;38(6):2892-903.


Three-dimensional radiobiological dosimetry (3D-RD) with 124I PET for 131I therapy of thyroid cancer.

Sgouros G, Hobbs RF, Atkins FB, Van Nostrand D, Ladenson PW, Wahl RL.

Eur J Nucl Med Mol Imaging. 2011 May;38 Suppl 1:S41-7. doi: 10.1007/s00259-011-1769-1. Epub 2011 Apr 12. Review.


Predicting hematologic toxicity in patients undergoing radioimmunotherapy with 90Y-ibritumomab tiuxetan or 131I-tositumomab.

Baechler S, Hobbs RF, Jacene HA, Bochud FO, Wahl RL, Sgouros G.

J Nucl Med. 2010 Dec;51(12):1878-84. doi: 10.2967/jnumed.110.079947.


A treatment planning method for sequentially combining radiopharmaceutical therapy and external radiation therapy.

Hobbs RF, McNutt T, Baechler S, He B, Esaias CE, Frey EC, Loeb DM, Wahl RL, Shokek O, Sgouros G.

Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1256-62. doi: 10.1016/j.ijrobp.2010.08.022. Epub 2010 Oct 13.


Fine-resolution voxel S values for constructing absorbed dose distributions at variable voxel size.

Dieudonné A, Hobbs RF, Bolch WE, Sgouros G, Gardin I.

J Nucl Med. 2010 Oct;51(10):1600-7. doi: 10.2967/jnumed.110.077149. Epub 2010 Sep 16.


Human biodistribution and radiation dosimetry of 82Rb.

Senthamizhchelvan S, Bravo PE, Esaias C, Lodge MA, Merrill J, Hobbs RF, Sgouros G, Bengel FM.

J Nucl Med. 2010 Oct;51(10):1592-9. doi: 10.2967/jnumed.110.077669. Epub 2010 Sep 16.


Tandem dosing of samarium-153 ethylenediamine tetramethylene phosphoric acid with stem cell support for patients with high-risk osteosarcoma.

Loeb DM, Hobbs RF, Okoli A, Chen AR, Cho S, Srinivasan S, Sgouros G, Shokek O, Wharam MD Jr, Scott T, Schwartz CL.

Cancer. 2010 Dec 1;116(23):5470-8. doi: 10.1002/cncr.25518. Epub 2010 Aug 16.


Arterial wall dosimetry for non-Hodgkin lymphoma patients treated with radioimmunotherapy.

Hobbs RF, Baechler S, Wahl RL, He B, Song H, Esaias CE, Frey EC, Jacene H, Sgouros G.

J Nucl Med. 2010 Mar;51(3):368-75. doi: 10.2967/jnumed.109.069575. Epub 2010 Feb 11.


A gamma camera count rate saturation correction method for whole-body planar imaging.

Hobbs RF, Baechler S, Senthamizhchelvan S, Prideaux AR, Esaias CE, Reinhardt M, Frey EC, Loeb DM, Sgouros G.

Phys Med Biol. 2010 Feb 7;55(3):817-31. doi: 10.1088/0031-9155/55/3/018. Epub 2010 Jan 14.

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