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High Quality Clinical Stereotactic Radiosurgery Planning and Delivery with Standard Resolution (5mm) Multileaf Collimation and Multiple Isocentres.

Robinson M, Tunstall C, Van den Heuvel F, Hobbs C, Padmanaban S.

Pract Radiat Oncol. 2020 Mar 19. pii: S1879-8500(20)30064-3. doi: 10.1016/j.prro.2020.03.004. [Epub ahead of print]


Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner.

Mahon OR, Browe DC, Gonzalez-Fernandez T, Pitacco P, Whelan IT, Von Euw S, Hobbs C, Nicolosi V, Cunningham KT, Mills KHG, Kelly DJ, Dunne A.

Biomaterials. 2020 May;239:119833. doi: 10.1016/j.biomaterials.2020.119833. Epub 2020 Jan 31.


Racial/Ethnic Disparity in the Incidence of Bronchiolitis Requiring Hospitalization.

Inagaki K, Blackshear C, Burns PA, Hobbs CV.

Clin Infect Dis. 2020 Feb 5. pii: ciaa113. doi: 10.1093/cid/ciaa113. [Epub ahead of print]


Mortality in a neonate with molybdenum cofactor deficiency illustrates the need for a comprehensive rapid precision medicine system.

Kingsmore SF, Ramchandar N, James K, Niemi AK, Feigenbaum A, Ding Y, Benson W, Hobbs C, Nahas S, Chowdhury S, Dimmock D.

Cold Spring Harb Mol Case Stud. 2020 Feb 3;6(1). pii: a004705. doi: 10.1101/mcs.a004705. Print 2020 Feb.


Reply to McGuire, et al.

Inagaki K, Lucar J, Blackshear C, Hobbs CV.

Clin Infect Dis. 2020 Feb 3. pii: ciaa110. doi: 10.1093/cid/ciaa110. [Epub ahead of print] No abstract available.


Comparison between self-administered depression questionnaires and patients' own views of changes in their mood: a prospective cohort study in primary care.

Hobbs C, Lewis G, Dowrick C, Kounali D, Peters TJ, Lewis G.

Psychol Med. 2020 Jan 20:1-8. doi: 10.1017/S0033291719003878. [Epub ahead of print]


Functionalising Collagen-Based Scaffolds With Platelet-Rich Plasma for Enhanced Skin Wound Healing Potential.

do Amaral RJFC, Zayed NMA, Pascu EI, Cavanagh B, Hobbs C, Santarella F, Simpson CR, Murphy CM, Sridharan R, González-Vázquez A, O'Sullivan B, O'Brien FJ, Kearney CJ.

Front Bioeng Biotechnol. 2019 Dec 3;7:371. doi: 10.3389/fbioe.2019.00371. eCollection 2019.


Antidepressant treatment with sertraline for adults with depressive symptoms in primary care: the PANDA research programme including RCT.

Duffy L, Lewis G, Ades A, Araya R, Bone J, Brabyn S, Button K, Churchill R, Croudace T, Derrick C, Dixon P, Dowrick C, Fawsitt C, Fusco L, Gilbody S, Harmer C, Hobbs C, Hollingworth W, Jones V, Kendrick T, Kessler D, Khan N, Kounali D, Lanham P, Malpass A, Munafo M, Pervin J, Peters T, Riozzie D, Robinson J, Salaminios G, Sharp D, Thom H, Thomas L, Welton N, Wiles N, Woodhouse R, Lewis G.

Southampton (UK): NIHR Journals Library; 2019 Dec.


Gene-by-gene interactions associated with the risk of conotruncal heart defects.

Lyu C, Webber DM, MacLeod SL, Hobbs CA, Li M; National Birth Defects Prevention Study.

Mol Genet Genomic Med. 2020 Jan;8(1):e1010. doi: 10.1002/mgg3.1010. Epub 2019 Dec 18.


Radiolabelling and immunohistochemistry reveal platelet recruitment into lungs and platelet migration into airspaces following LPS inhalation in mice.

Cleary SJ, Rauzi F, Smyth E, Correia A, Hobbs C, Emerson M, Page CP, Pitchford SC.

J Pharmacol Toxicol Methods. 2020 Mar - Apr;102:106660. doi: 10.1016/j.vascn.2019.106660. Epub 2019 Dec 12.


In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model.

Williams IP, Crescioli S, Sow HS, Bax HJ, Hobbs C, Ilieva KM, French E, Pellizzari G, Cox V, Josephs DH, Spicer JF, Karagiannis SN, Mele S.

MAbs. 2020 Jan-Dec;12(1):1685349. doi: 10.1080/19420862.2019.1685349.


RARβ Agonist Drug (C286) Demonstrates Efficacy in a Pre-clinical Neuropathic Pain Model Restoring Multiple Pathways via DNA Repair Mechanisms.

Goncalves MB, Moehlin J, Clarke E, Grist J, Hobbs C, Carr AM, Jack J, Mendoza-Parra MA, Corcoran JPT.

iScience. 2019 Nov 22;21:562-563. doi: 10.1016/j.isci.2019.10.068. Epub 2019 Nov 11. No abstract available.


RARβ Agonist Drug (C286) Demonstrates Efficacy in a Pre-clinical Neuropathic Pain Model Restoring Multiple Pathways via DNA Repair Mechanisms.

Goncalves MB, Moehlin J, Clarke E, Grist J, Hobbs C, Carr AM, Jack J, Mendoza-Parra MA, Corcoran JPT.

iScience. 2019 Oct 25;20:554-566. doi: 10.1016/j.isci.2019.09.020. Epub 2019 Sep 17. Erratum in: iScience. 2019 Nov 22;21:562-563.


Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure.

Smith-Roe SL, Wyde ME, Stout MD, Winters JW, Hobbs CA, Shepard KG, Green AS, Kissling GE, Shockley KR, Tice RR, Bucher JR, Witt KL.

Environ Mol Mutagen. 2020 Feb;61(2):276-290. doi: 10.1002/em.22343. Epub 2019 Nov 13.


Pediatric Appendicitis-Factors Associated With Surgical Approach, Complications, and Readmission.

Inagaki K, Blackshear C, Morris MW, Hobbs CV.

J Surg Res. 2020 Feb;246:395-402. doi: 10.1016/j.jss.2019.09.031. Epub 2019 Oct 16.


Chemoprophylaxis vaccination: Phase 1 study to explore stage-specific immunity to Plasmodium falciparum in U.S. adults.

Healy SA, Murphy SC, Hume JCC, Shelton L, Kuntz S, Van Voorhis WC, Moodie Z, Metch B, Wang R, Silver-Brace T, Fishbaugher M, Kennedy M, Finney OC, Chaturvedi R, Hobbs CV, Warner-Lubin M, Talley AK, Wong-Madden S, Stuart K, Wald A, Kappe SH, Kublin JG, Duffy PE.

Clin Infect Dis. 2019 Oct 17. pii: ciz1010. doi: 10.1093/cid/ciz1010. [Epub ahead of print]


A Randomized, Controlled Trial of the Analytic and Diagnostic Performance of Singleton and Trio, Rapid Genome and Exome Sequencing in Ill Infants.

Kingsmore SF, Cakici JA, Clark MM, Gaughran M, Feddock M, Batalov S, Bainbridge MN, Carroll J, Caylor SA, Clarke C, Ding Y, Ellsworth K, Farnaes L, Hildreth A, Hobbs C, James K, Kint CI, Lenberg J, Nahas S, Prince L, Reyes I, Salz L, Sanford E, Schols P, Sweeney N, Tokita M, Veeraraghavan N, Watkins K, Wigby K, Wong T, Chowdhury S, Wright MS, Dimmock D; RCIGM Investigators.

Am J Hum Genet. 2019 Oct 3;105(4):719-733. doi: 10.1016/j.ajhg.2019.08.009. Epub 2019 Sep 26.


Deep Neck Space Involvement of Kawasaki Disease in the US: A Population-Based Study.

Inagaki K, Blackshear C, Hobbs CV.

J Pediatr. 2019 Dec;215:118-122. doi: 10.1016/j.jpeds.2019.07.054. Epub 2019 Aug 30.


Induced pluripotent stem cell line heterozygous for p.R501X mutation in filaggrin: KCLi003-A.

Kolundzic N, Khurana P, Devito L, Jeriha J, Marx J, Hobbs C, Wong XFCC, Common JEA, Liovic M, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D.

Stem Cell Res. 2019 Aug;39:101527. doi: 10.1016/j.scr.2019.101527. Epub 2019 Aug 7.


Hypospadias Prevalence and Trends in International Birth Defect Surveillance Systems, 1980-2010.

Yu X, Nassar N, Mastroiacovo P, Canfield M, Groisman B, Bermejo-Sánchez E, Ritvanen A, Kiuru-Kuhlefelt S, Benavides A, Sipek A, Pierini A, Bianchi F, Källén K, Gatt M, Morgan M, Tucker D, Canessa MA, Gajardo R, Mutchinick OM, Szabova E, Csáky-Szunyogh M, Tagliabue G, Cragan JD, Nembhard WN, Rissmann A, Goetz D, Bower C, Baynam G, Lowry RB, Leon JA, Luo W, Rouleau J, Zarante I, Fernandez N, Amar E, Dastgiri S, Contiero P, Martínez-de-Villarreal LE, Borman B, Bergman JEH, de Walle HEK, Hobbs CA, Nance AE, Agopian AJ.

Eur Urol. 2019 Oct;76(4):482-490. doi: 10.1016/j.eururo.2019.06.027. Epub 2019 Jul 9.


Keeping Dr. Charles Richard Drew's legacy alive.

Parker-Kelly D, Hobbs CP.

J Med Libr Assoc. 2019 Jul;107(3):449-453. doi: 10.5195/jmla.2019.726. Epub 2019 Jul 1.


Corrigendum to "Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury" [Bioorg. Med. Chem. Lett. 29(8) (2019) 995-1000].

Goncalves MB, Clarke E, Jarvis CI, Kalindjian SB, Pitcher T, Grist J, Hobbs C, Carlstedt T, Jack J, Brown JT, Mills M, Mumford P, Borthwick AD, Corcoran JPT.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2440-2441. doi: 10.1016/j.bmcl.2019.05.058. Epub 2019 Jun 14. No abstract available.


Detailed Multi-Dimensional Assessment of Fatigue in Inflammatory Bowel Disease.

Aluzaite K, Al-Mandhari R, Osborne H, Ho C, Williams M, Sullivan MM, Hobbs CE, Schultz M.

Inflamm Intest Dis. 2019 Apr;3(4):192-201. doi: 10.1159/000496054. Epub 2019 Mar 15.


Induced pluripotent stem cell line heterozygous for p.R2447X mutation in filaggrin: KCLi002-A.

Kolundzic N, Khurana P, Devito L, Donne M, Hobbs C, Jeriha J, Wong XFCC, Common JAE, Lane EB, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D.

Stem Cell Res. 2019 Jul;38:101462. doi: 10.1016/j.scr.2019.101462. Epub 2019 May 13.


The role of genetic variation in DGKK on moderate and severe hypospadias.

Richard MA, Sok P, Canon S, Brown AL, Peckham-Gregory EC, Nembhard WN, Carmichael SL, Ehli EA, Kallsen NA, Peyton SA, Davies GE, Patel A, Zamilpa I, Wyatt RA, Hobbs CA, Scheurer ME, Lupo PJ.

Birth Defects Res. 2019 Aug 1;111(13):932-937. doi: 10.1002/bdr2.1522. Epub 2019 May 18.


BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.

Lee EF, Harris TJ, Tran S, Evangelista M, Arulananda S, John T, Ramnac C, Hobbs C, Zhu H, Gunasingh G, Segal D, Behren A, Cebon J, Dobrovic A, Mariadason JM, Strasser A, Rohrbeck L, Haass NK, Herold MJ, Fairlie WD.

Cell Death Dis. 2019 Apr 24;10(5):342. doi: 10.1038/s41419-019-1568-3.


Disruption of the Sensory System Affects Sterile Cutaneous Inflammation In Vivo.

La Russa F, Lopes DM, Hobbs C, Argunhan F, Brain S, Bevan S, Bennett DLH, McMahon SB.

J Invest Dermatol. 2019 Sep;139(9):1936-1945.e3. doi: 10.1016/j.jid.2019.01.037. Epub 2019 Apr 8.


Recent Advances in Bio-Based Flame Retardant Additives for Synthetic Polymeric Materials.

Hobbs CE.

Polymers (Basel). 2019 Jan 31;11(2). pii: E224. doi: 10.3390/polym11020224. Review.


Induced pluripotent stem cell (iPSC) line from an epidermolysis bullosa simplex patient heterozygous for keratin 5 E475G mutation and with the Dowling Meara phenotype.

Kolundzic N, Khurana P, Hobbs C, Rogar M, Ropret S, Törmä H, Ilic D, Liovic M.

Stem Cell Res. 2019 May;37:101424. doi: 10.1016/j.scr.2019.101424. Epub 2019 Mar 27.


Comparison of human isogeneic Wharton's jelly MSCs and iPSC-derived MSCs reveals differentiation-dependent metabolic responses to IFNG stimulation.

Devito L, Klontzas ME, Cvoro A, Galleu A, Simon M, Hobbs C, Dazzi F, Mantalaris A, Khalaf Y, Ilic D.

Cell Death Dis. 2019 Mar 20;10(4):277. doi: 10.1038/s41419-019-1498-0.


Case Report: Ocular Toxocariasis: A Report of Three Cases from the Mississippi Delta.

Inagaki K, Kirmse B, Bradbury RS, Moorthy RS, Arguello I, McGuffey CD, Tieu B, Hobbs CV.

Am J Trop Med Hyg. 2019 May;100(5):1223-1226. doi: 10.4269/ajtmh.18-0766.


Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues.

Gonzalez-Fernandez T, Rathan S, Hobbs C, Pitacco P, Freeman FE, Cunniffe GM, Dunne NJ, McCarthy HO, Nicolosi V, O'Brien FJ, Kelly DJ.

J Control Release. 2019 May 10;301:13-27. doi: 10.1016/j.jconrel.2019.03.006. Epub 2019 Mar 8.


Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury.

Goncalves MB, Clarke E, Jarvis CI, Barret Kalindjian S, Pitcher T, Grist J, Hobbs C, Carlstedt T, Jack J, Brown JT, Mills M, Mumford P, Borthwick AD, Corcoran JPT.

Bioorg Med Chem Lett. 2019 Apr 15;29(8):995-1000. doi: 10.1016/j.bmcl.2019.02.011. Epub 2019 Feb 11. Erratum in: Bioorg Med Chem Lett. 2019 Aug 15;29(16):2440-2441.


LPS-induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-Selectin.

Cleary SJ, Hobbs C, Amison RT, Arnold S, O'Shaughnessy BG, Lefrançais E, Mallavia B, Looney MR, Page CP, Pitchford SC.

Am J Respir Cell Mol Biol. 2019 Aug;61(2):232-243. doi: 10.1165/rcmb.2018-0182OC.


Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells.

Goncalves MB, Wu Y, Clarke E, Grist J, Hobbs C, Trigo D, Jack J, Corcoran JPT.

J Neurosci. 2019 Apr 17;39(16):3013-3027. doi: 10.1523/JNEUROSCI.2922-18.2019. Epub 2019 Feb 13.


Collagen scaffolds functionalised with copper-eluting bioactive glass reduce infection and enhance osteogenesis and angiogenesis both in vitro and in vivo.

Ryan EJ, Ryan AJ, González-Vázquez A, Philippart A, Ciraldo FE, Hobbs C, Nicolosi V, Boccaccini AR, Kearney CJ, O'Brien FJ.

Biomaterials. 2019 Mar;197:405-416. doi: 10.1016/j.biomaterials.2019.01.031. Epub 2019 Jan 23.


Using DNA Barcoding to Investigate Patterns of Species Utilisation in UK Shark Products Reveals Threatened Species on Sale.

Hobbs CAD, Potts RWA, Bjerregaard Walsh M, Usher J, Griffiths AM.

Sci Rep. 2019 Jan 31;9(1):1028. doi: 10.1038/s41598-018-38270-3.


Annual Incidence and Phenotypic Presentation of IBD in Southern New Zealand: An 18-Year Epidemiological Analysis.

Coppell KJ, Galts CP, Huizing FY, Norton JK, Gray AR, Schultz K, Hobbs CE, Aluzaite K, Schultz M.

Inflamm Intest Dis. 2018 Nov;3(1):32-39. doi: 10.1159/000492615. Epub 2018 Sep 17.


Bronchopulmonary Dysplasia in Very Preterm Infants with Symptomatic Congenital Cytomegalovirus Infection: A Propensity Score-Matched Analysis.

Inagaki K, Blackshear C, Hobbs CV.

J Pediatr. 2019 Jan;204:142-147.e1. doi: 10.1016/j.jpeds.2018.08.038. Epub 2018 Sep 27.


Comparison of Prostate Biopsy with or without Prebiopsy Multiparametric Magnetic Resonance Imaging for Prostate Cancer Detection: An Observational Cohort Study.

Bryant RJ, Hobbs CP, Eyre KS, Davies LC, Sullivan ME, Shields W, Sooriakumaran P, Verrill CL, Gleeson FV, MacPherson RE, Hamdy FC, Brewster SF.

J Urol. 2019 Mar;201(3):510-519. doi: 10.1016/j.juro.2018.09.049.


Stereotactic Body Radiotherapy for Medically Inoperable Stage I-II Non-Small Cell Lung Cancer: The Mayo Clinic Experience.

Hobbs CJ, Ko SJ, Paryani NN, Accurso JM, Olivier KR, Garces YI, Park SS, Hallemeier CL, Schild SE, Vora SA, Ashman JB, Rule WG, Bowers JR, Heckman MG, Diehl NN, Miller RC.

Mayo Clin Proc Innov Qual Outcomes. 2017 Dec 26;2(1):40-48. doi: 10.1016/j.mayocpiqo.2017.11.001. eCollection 2018 Mar.


Brief Report: Antimalarial Benefit of HIV Antiretroviral Therapy in Areas of Low to Moderate Malaria Transmission Intensity.

Greenhalgh S, Hobbs CV, Parikh S.

J Acquir Immune Defic Syndr. 2018 Oct 1;79(2):249-254. doi: 10.1097/QAI.0000000000001783.


Optimising complementary soft tissue synchrotron X-ray microtomography for reversibly-stained central nervous system samples.

Strotton MC, Bodey AJ, Wanelik K, Darrow MC, Medina E, Hobbs C, Rau C, Bradbury EJ.

Sci Rep. 2018 Aug 13;8(1):12017. doi: 10.1038/s41598-018-30520-8.


Role of pathology peer review in interpretation of the comet assay.

Maronpot RR, Hobbs CA, Hayashi SM.

J Toxicol Pathol. 2018 Jul;31(3):155-161. doi: 10.1293/tox.2018-0019. Epub 2018 May 11. Review.


Induced pluripotent stem cell line from an atopic dermatitis patient heterozygous for c.2282del4 mutation in filaggrin: KCLi001-A.

Devito L, Donne M, Kolundzic N, Khurana P, Hobbs C, Kaddour G, Dubrac S, Gruber R, Schmuth M, Mauro T, Ilic D.

Stem Cell Res. 2018 Aug;31:122-126. doi: 10.1016/j.scr.2018.07.014. Epub 2018 Jul 25.


PDGFRA gene, maternal binge drinking and obstructive heart defects.

Tang X, Eberhart JK, Cleves MA, Li J, Li M, MacLeod S, Nembhard WN, Hobbs CA.

Sci Rep. 2018 Jul 23;8(1):11083. doi: 10.1038/s41598-018-29160-9.


Genotoxicity evaluation of the naturally-derived food colorant, gardenia blue, and its precursor, genipin.

Hobbs CA, Koyanagi M, Swartz C, Davis J, Maronpot R, Recio L, Hayashi SM.

Food Chem Toxicol. 2018 Aug;118:695-708. doi: 10.1016/j.fct.2018.06.001. Epub 2018 Jun 4.


Pneumocystis Infection in Children: National Trends and Characteristics in the United States, 1997-2012.

Inagaki K, Blackshear C, Hobbs CV.

Pediatr Infect Dis J. 2019 Mar;38(3):241-247. doi: 10.1097/INF.0000000000002119.


Risk Factors, Geographic Distribution, and Healthcare Burden of Symptomatic Congenital Cytomegalovirus Infection in the United States: Analysis of a Nationally Representative Database, 2000-2012.

Inagaki K, Blackshear C, Palmer A, Hobbs CV.

J Pediatr. 2018 Aug;199:118-123.e1. doi: 10.1016/j.jpeds.2018.03.036. Epub 2018 Apr 26.


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