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Items: 1 to 50 of 245

1.

Ularcirc: visualization and enhanced analysis of circular RNAs via back and canonical forward splicing.

Humphreys DT, Fossat N, Demuth M, Tam PPL, Ho JWK.

Nucleic Acids Res. 2019 Aug 22. pii: gkz718. doi: 10.1093/nar/gkz718. [Epub ahead of print]

PMID:
31435647
2.

Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells.

Le TYL, Pickett HA, Yang A, Ho JWK, Thavapalachandran S, Igoor S, Yang SF, Farraha M, Voges HK, Hudson JE, Dos Remedios CG, Bryan TM, Kizana E, Chong JJH.

Sci Rep. 2019 Jul 22;9(1):10579. doi: 10.1038/s41598-019-47022-w.

3.

Optical design considerations of rear-side dielectric for higher efficiency of PERC solar cells.

Lai D, Tan CS, Ke C, Ho JW, Ang PC, Kam ZM, Aberle AG, Huang Y.

Opt Express. 2019 Jun 10;27(12):A758-A765. doi: 10.1364/OE.27.00A758.

PMID:
31252852
4.

Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures.

Wu S, Tan KJ, Govindarajan LN, Stewart JC, Gu L, Ho JWH, Katarya M, Wong BH, Tan EK, Li D, Claridge-Chang A, Libedinsky C, Cheng L, Aw SS.

PLoS Biol. 2019 Jun 27;17(6):e3000346. doi: 10.1371/journal.pbio.3000346. eCollection 2019 Jun.

5.

Dam mutants provide improved sensitivity and spatial resolution for profiling transcription factor binding.

Szczesnik T, Ho JWK, Sherwood R.

Epigenetics Chromatin. 2019 Jun 13;12(1):36. doi: 10.1186/s13072-019-0273-x.

6.

Targeted Transgene Activation in the Brain Tissue by Systemic Delivery of Engineered AAV1 Expressing CRISPRa.

Lau CH, Ho JW, Lo PK, Tin C.

Mol Ther Nucleic Acids. 2019 Jun 7;16:637-649. doi: 10.1016/j.omtn.2019.04.015. Epub 2019 Apr 23.

7.

Discovery of perturbation gene targets via free text metadata mining in Gene Expression Omnibus.

Djordjevic D, Tang JYS, Chen YX, Kwan SLS, Ling RWK, Qian G, Woo CYY, Ellis SJ, Ho JWK.

Comput Biol Chem. 2019 Jun;80:152-158. doi: 10.1016/j.compbiolchem.2019.03.014. Epub 2019 Mar 24.

PMID:
30959271
8.

Ultrafast clustering of single-cell flow cytometry data using FlowGrid.

Ye X, Ho JWK.

BMC Syst Biol. 2019 Apr 5;13(Suppl 2):35. doi: 10.1186/s12918-019-0690-2.

9.

Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury.

Farbehi N, Patrick R, Dorison A, Xaymardan M, Janbandhu V, Wystub-Lis K, Ho JW, Nordon RE, Harvey RP.

Elife. 2019 Mar 26;8. pii: e43882. doi: 10.7554/eLife.43882.

10.

Big data: the elements of good questions, open data, and powerful software.

Ho JWK, Giannoulatou E.

Biophys Rev. 2019 Feb;11(1):1-3. doi: 10.1007/s12551-019-00500-x. Epub 2019 Jan 25. No abstract available.

11.

CardiacProfileR: an R package for extraction and visualisation of heart rate profiles from wearable fitness trackers.

Djordjevic D, Cawood BK, Rispin SK, Shah A, Yim LHH, Hayward CS, Ho JWK.

Biophys Rev. 2019 Feb;11(1):119-121. doi: 10.1007/s12551-019-00498-2. Epub 2019 Jan 21. No abstract available.

12.

Host and microbiome multi-omics integration: applications and methodologies.

Wang Q, Wang K, Wu W, Giannoulatou E, Ho JWK, Li L.

Biophys Rev. 2019 Feb;11(1):55-65. doi: 10.1007/s12551-018-0491-7. Epub 2019 Jan 9. Review.

13.

Identification of active signaling pathways by integrating gene expression and protein interaction data.

Kabir MH, Patrick R, Ho JWK, O'Connor MD.

BMC Syst Biol. 2018 Dec 31;12(Suppl 9):120. doi: 10.1186/s12918-018-0655-x.

14.

Ultrafast Excited-State Dynamics of Hydrogen-Bonded Cytosine Microsolvated Clusters with Protic and Aprotic Polar Solvents.

Wei SC, Ho JW, Yen HC, Shi HQ, Cheng LH, Weng CN, Chou WK, Chiu CC, Cheng PY.

J Phys Chem A. 2018 Dec 13;122(49):9412-9425. doi: 10.1021/acs.jpca.8b09526. Epub 2018 Nov 30.

PMID:
30452255
15.

C3: An R package for cross-species compendium-based cell-type identification.

Kabir MH, Djordjevic D, O'Connor MD, Ho JWK.

Comput Biol Chem. 2018 Dec;77:187-192. doi: 10.1016/j.compbiolchem.2018.10.003. Epub 2018 Oct 9.

PMID:
30340080
16.

Identification of clinically actionable variants from genome sequencing of families with congenital heart disease.

Alankarage D, Ip E, Szot JO, Munro J, Blue GM, Harrison K, Cuny H, Enriquez A, Troup M, Humphreys DT, Wilson M, Harvey RP, Sholler GF, Graham RM, Ho JWK, Kirk EP, Pachter N, Chapman G, Winlaw DS, Giannoulatou E, Dunwoodie SL.

Genet Med. 2019 May;21(5):1111-1120. doi: 10.1038/s41436-018-0296-x. Epub 2018 Oct 8.

PMID:
30293987
17.

Are we taking a risk with risk assessment tools? Evaluating the relationship between NSQIP and the ACS risk calculator in colorectal surgery.

Keller DS, Ho JW, Mercadel AJ, Ogola GO, Steele SR.

Am J Surg. 2018 Oct;216(4):645-651. doi: 10.1016/j.amjsurg.2018.07.015. Epub 2018 Jul 19.

PMID:
30049434
18.

Dietary and Physical Activity Interventions for Colorectal Cancer Survivors: A Randomized Controlled Trial.

Lee CF, Ho JWC, Fong DYT, Macfarlane DJ, Cerin E, Lee AM, Leung S, Chan WYY, Leung IPF, Lam SHS, Chu N, Taylor AJ, Cheng KK.

Sci Rep. 2018 Apr 10;8(1):5731. doi: 10.1038/s41598-018-24042-6.

19.

A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data.

Szot JO, Cuny H, Blue GM, Humphreys DT, Ip E, Harrison K, Sholler GF, Giannoulatou E, Leo P, Duncan EL, Sparrow DB, Ho JWK, Graham RM, Pachter N, Chapman G, Winlaw DS, Dunwoodie SL.

Circ Genom Precis Med. 2018 Mar;11(3):e001978. doi: 10.1161/CIRCGEN.117.001978.

PMID:
29555671
20.

Biologically active constituents of the secretome of human W8B2+ cardiac stem cells.

Nie S, Wang X, Sivakumaran P, Chong MMW, Liu X, Karnezis T, Bandara N, Takov K, Nowell CJ, Wilcox S, Shambrook M, Hill AF, Harris NC, Newcomb AE, Strappe P, Shayan R, Hernández D, Clarke J, Hanssen E, Davidson SM, Dusting GJ, Pébay A, Ho JWK, Williamson N, Lim SY.

Sci Rep. 2018 Jan 25;8(1):1579. doi: 10.1038/s41598-018-19855-4.

21.

Discovery of cell-type specific DNA motif grammar in cis-regulatory elements using random Forest.

Wang X, Lin P, Ho JWK.

BMC Genomics. 2018 Jan 19;19(Suppl 1):929. doi: 10.1186/s12864-017-4340-z.

22.

Identification of satellite cells from anole lizard skeletal muscle and demonstration of expanded musculoskeletal potential.

Palade J, Djordjevic D, Hutchins ED, George RM, Cornelius JA, Rawls A, Ho JWK, Kusumi K, Wilson-Rawls J.

Dev Biol. 2018 Jan 15;433(2):344-356. doi: 10.1016/j.ydbio.2017.08.037. Epub 2017 Dec 25.

23.

Light-focusing human micro-lenses generated from pluripotent stem cells model lens development and drug-induced cataract in vitro.

Murphy P, Kabir MH, Srivastava T, Mason ME, Dewi CU, Lim S, Yang A, Djordjevic D, Killingsworth MC, Ho JWK, Harman DG, O'Connor MD.

Development. 2018 Jan 9;145(1). pii: dev155838. doi: 10.1242/dev.155838.

24.

Watching proton transfer in real time: Ultrafast photoionization-induced proton transfer in phenol-ammonia complex cation.

Shen CC, Tsai TT, Wu JY, Ho JW, Chen YW, Cheng PY.

J Chem Phys. 2017 Oct 28;147(16):164302. doi: 10.1063/1.5001375.

PMID:
29096460
25.

iSyTE 2.0: a database for expression-based gene discovery in the eye.

Kakrana A, Yang A, Anand D, Djordjevic D, Ramachandruni D, Singh A, Huang H, Ho JWK, Lachke SA.

Nucleic Acids Res. 2018 Jan 4;46(D1):D875-D885. doi: 10.1093/nar/gkx837.

26.

Impact of sequencing depth and read length on single cell RNA sequencing data of T cells.

Rizzetto S, Eltahla AA, Lin P, Bull R, Lloyd AR, Ho JWK, Venturi V, Luciani F.

Sci Rep. 2017 Oct 6;7(1):12781. doi: 10.1038/s41598-017-12989-x.

27.

Maternal obesity heritably perturbs offspring metabolism for three generations without serial programming.

Eaton SA, Aiken AJ, Young PE, Ho JWK, Cropley JE, Suter CM.

Int J Obes (Lond). 2018 Apr;42(4):911-914. doi: 10.1038/ijo.2017.247. Epub 2017 Oct 6.

PMID:
28984844
28.

Community Care for People with Complex Care Needs: Bridging the Gap between Health and Social Care.

Kuluski K, Ho JW, Hans PK, Nelson M.

Int J Integr Care. 2017 Jul 21;17(4):2. doi: 10.5334/ijic.2944.

29.

A rare cause of sciatica discovered during digital rectal examination: case report of an intrapelvic sciatic notch schwannoma.

Woo PYM, Ho JMK, Ho JWK, Mak CHK, Wong AKS, Wong HT, Chan KY.

Br J Neurosurg. 2019 Oct;33(5):562-565. doi: 10.1080/02688697.2017.1378801. Epub 2017 Sep 14.

PMID:
28906149
30.

An Embryonic and Induced Pluripotent Stem Cell Model for Ovarian Granulosa Cell Development and Steroidogenesis.

Lipskind S, Lindsey JS, Gerami-Naini B, Eaton JL, O'Connell D, Kiezun A, Ho JWK, Ng N, Parasar P, Ng M, Nickerson M, Demirci U, Maas R, Anchan RM.

Reprod Sci. 2018 May;25(5):712-726. doi: 10.1177/1933719117725814. Epub 2017 Aug 31.

31.

Scalability and Validation of Big Data Bioinformatics Software.

Yang A, Troup M, Ho JWK.

Comput Struct Biotechnol J. 2017 Jul 20;15:379-386. doi: 10.1016/j.csbj.2017.07.002. eCollection 2017. Review.

32.

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

Shi H, Enriquez A, Rapadas M, Martin EMMA, Wang R, Moreau J, Lim CK, Szot JO, Ip E, Hughes JN, Sugimoto K, Humphreys DT, McInerney-Leo AM, Leo PJ, Maghzal GJ, Halliday J, Smith J, Colley A, Mark PR, Collins F, Sillence DO, Winlaw DS, Ho JWK, Guillemin GJ, Brown MA, Kikuchi K, Thomas PQ, Stocker R, Giannoulatou E, Chapman G, Duncan EL, Sparrow DB, Dunwoodie SL.

N Engl J Med. 2017 Aug 10;377(6):544-552. doi: 10.1056/NEJMoa1616361.

33.

Modelling, inference and big data in biophysics.

Ho JWK, Grant GH.

Biophys Rev. 2017 Aug;9(4):297-298. doi: 10.1007/s12551-017-0282-6. Epub 2017 Jul 30.

34.

"It's a fight to get anything you need" - Accessing care in the community from the perspectives of people with multimorbidity.

Ho JW, Kuluski K, Im J.

Health Expect. 2017 Dec;20(6):1311-1319. doi: 10.1111/hex.12571. Epub 2017 May 24.

35.

CIDR: Ultrafast and accurate clustering through imputation for single-cell RNA-seq data.

Lin P, Troup M, Ho JW.

Genome Biol. 2017 Mar 28;18(1):59. doi: 10.1186/s13059-017-1188-0.

36.

Integrative analysis identifies co-dependent gene expression regulation of BRG1 and CHD7 at distal regulatory sites in embryonic stem cells.

Yang P, Oldfield A, Kim T, Yang A, Yang JYH, Ho JWK.

Bioinformatics. 2017 Jul 1;33(13):1916-1920. doi: 10.1093/bioinformatics/btx092.

37.

PBrowse: a web-based platform for real-time collaborative exploration of genomic data.

Szot PS, Yang A, Wang X, Parsania C, Röhm U, Wong KH, Ho JWK.

Nucleic Acids Res. 2017 May 19;45(9):e67. doi: 10.1093/nar/gkw1358.

38.

Falco: a quick and flexible single-cell RNA-seq processing framework on the cloud.

Yang A, Troup M, Lin P, Ho JW.

Bioinformatics. 2017 Mar 1;33(5):767-769. doi: 10.1093/bioinformatics/btw732.

PMID:
28025200
39.

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity.

Cropley JE, Eaton SA, Aiken A, Young PE, Giannoulatou E, Ho JWK, Buckland ME, Keam SP, Hutvagner G, Humphreys DT, Langley KG, Henstridge DC, Martin DIK, Febbraio MA, Suter CM.

Mol Metab. 2016 Jun 23;5(8):699-708. doi: 10.1016/j.molmet.2016.06.008. eCollection 2016 Aug.

40.

XGSA: A statistical method for cross-species gene set analysis.

Djordjevic D, Kusumi K, Ho JW.

Bioinformatics. 2016 Sep 1;32(17):i620-i628. doi: 10.1093/bioinformatics/btw428.

PMID:
27587682
41.

Microbiological profiles of fungal keratitis: a 10-year study at a tertiary referral center.

Ho JW, Fernandez MM, Rebong RA, Carlson AN, Kim T, Afshari NA.

J Ophthalmic Inflamm Infect. 2016 Dec;6(1):5. doi: 10.1186/s12348-016-0071-6. Epub 2016 Feb 20.

42.

Intra-arterial revascularization therapy for basilar artery occlusion-a systematic review and analysis.

Mak CH, Ho JW, Chan KY, Poon WS, Wong GK.

Neurosurg Rev. 2016 Oct;39(4):575-80. doi: 10.1007/s10143-015-0693-4. Epub 2016 Jan 25. Review.

PMID:
26810313
43.

Mitochondrial Delivery of Therapeutic Agents by Amphiphilic DNA Nanocarriers.

Chan MS, Tam DY, Dai Z, Liu LS, Ho JW, Chan ML, Xu D, Wong MS, Tin C, Lo PK.

Small. 2016 Feb 10;12(6):770-81. doi: 10.1002/smll.201503051. Epub 2015 Dec 21.

PMID:
26690974
44.

Binding of transcription factor GabR to DNA requires recognition of DNA shape at a location distinct from its cognate binding site.

Al-Zyoud WA, Hynson RM, Ganuelas LA, Coster AC, Duff AP, Baker MA, Stewart AG, Giannoulatou E, Ho JW, Gaus K, Liu D, Lee LK, Böcking T.

Nucleic Acids Res. 2016 Feb 18;44(3):1411-20. doi: 10.1093/nar/gkv1466. Epub 2015 Dec 17.

45.

Crim1 regulates integrin signaling in murine lens development.

Zhang Y, Fan J, Ho JW, Hu T, Kneeland SC, Fan X, Xi Q, Sellarole MA, de Vries WN, Lu W, Lachke SA, Lang RA, John SW, Maas RL.

Development. 2016 Jan 15;143(2):356-66. doi: 10.1242/dev.125591. Epub 2015 Dec 17.

46.

Microhydration Effects on the Ultrafast Photodynamics of Cytosine: Evidences for a Possible Hydration-Site Dependence.

Ho JW, Yen HC, Shi HQ, Cheng LH, Weng CN, Chou WK, Chiu CC, Cheng PY.

Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14772-6. doi: 10.1002/anie.201507524. Epub 2015 Oct 22.

PMID:
26489530
47.

5-Hydroxytryptamine promotes hepatocellular carcinoma proliferation by influencing β-catenin.

Fatima S, Shi X, Lin Z, Chen GQ, Pan XH, Wu JC, Ho JW, Lee NP, Gao H, Zhang G, Lu A, Bian ZX.

Mol Oncol. 2016 Feb;10(2):195-212. doi: 10.1016/j.molonc.2015.09.008. Epub 2015 Sep 30.

48.

Bidirectional Modulation of Recognition Memory.

Ho JW, Poeta DL, Jacobson TK, Zolnik TA, Neske GT, Connors BW, Burwell RD.

J Neurosci. 2015 Sep 30;35(39):13323-35. doi: 10.1523/JNEUROSCI.2278-15.2015.

49.

How to test bioinformatics software?

Kamali AH, Giannoulatou E, Chen TY, Charleston MA, McEwan AL, Ho JWK.

Biophys Rev. 2015 Sep;7(3):343-352. doi: 10.1007/s12551-015-0177-3. Epub 2015 Aug 13. Review.

50.

Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.

Movahedi M, Bishop DT, Macrae F, Mecklin JP, Moeslein G, Olschwang S, Eccles D, Evans DG, Maher ER, Bertario L, Bisgaard ML, Dunlop MG, Ho JW, Hodgson SV, Lindblom A, Lubinski J, Morrison PJ, Murday V, Ramesar RS, Side L, Scott RJ, Thomas HJ, Vasen HF, Burn J, Mathers JC.

J Clin Oncol. 2015 Nov 1;33(31):3591-7. doi: 10.1200/JCO.2014.58.9952. Epub 2015 Aug 17.

PMID:
26282643

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