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Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458.

Chen YF, Li YJ, Chou CH, Chiew MY, Huang HD, Ho JH, Chien S, Lee OK.

Sci Adv. 2020 Feb 5;6(6):eaay0264. doi: 10.1126/sciadv.aay0264. eCollection 2020 Feb.


Synthesis and In Vitro Photocytotoxicity of 9-/13-Lipophilic Substituted Berberine Derivatives as Potential Anticancer Agents.

Lin HJ, Ho JH, Tsai LC, Yang FY, Yang LL, Kuo CD, Chen LG, Liu YW, Wu JY.

Molecules. 2020 Feb 5;25(3). pii: E677. doi: 10.3390/molecules25030677.


Small fibre pathology is associated with erectile dysfunction in men with type 2 diabetes.

Dhage S, Ho JH, Ferdousi M, Kalteniece A, Azmi S, Adam S, Marshall A, Jeziorska M, Donn R, Soran H, Malik RA.

Diabetes Metab Res Rev. 2019 Dec 13:e3263. doi: 10.1002/dmrr.3263. [Epub ahead of print]


The busyness of medicine.

Ho JH, Dubash R, Kozlovski J.

Emerg Med Australas. 2019 Dec;31(6):1101-1103. doi: 10.1111/1742-6723.13428. Epub 2019 Nov 26. No abstract available.


Efficacy and safety of PCSK9 monoclonal antibodies.

Iqbal Z, Dhage S, Mohamad JB, Abdel-Razik A, Donn R, Malik R, Ho JH, Liu Y, Adam S, Isa B, Stefanutti C, Soran H.

Expert Opin Drug Saf. 2019 Dec;18(12):1191-1201. doi: 10.1080/14740338.2019.1681395. Epub 2019 Nov 20. Review.


Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist.

Laprairie RB, Vemuri K, Stahl EL, Korde A, Ho JH, Grim TW, Hua T, Wu Y, Stevens RC, Liu ZJ, Makriyannis A, Bohn LM.

Mol Pharmacol. 2019 Nov;96(5):619-628. doi: 10.1124/mol.119.116483. Epub 2019 Sep 12.


Male sexual dysfunction in obesity: The role of sex hormones and small fibre neuropathy.

Ho JH, Adam S, Azmi S, Ferdousi M, Liu Y, Kalteniece A, Dhage SS, Keevil BG, Syed AA, Ammori BJ, Ahern T, Donn R, Malik RA, Soran H.

PLoS One. 2019 Sep 11;14(9):e0221992. doi: 10.1371/journal.pone.0221992. eCollection 2019.


The fine line between emergency resident and registrar.

Tran V, Ho JH, Kozlovski J, Cobbett J, Dubash R.

Emerg Med Australas. 2019 Oct;31(5):869-871. doi: 10.1111/1742-6723.13388. Epub 2019 Sep 8. No abstract available.


Mesenchymal stem cells restore the sperm motility from testicular torsion-detorsion injury by regulation of glucose metabolism in sperm.

Hsiao CH, Ji AT, Chang CC, Chien MH, Lee LM, Ho JH.

Stem Cell Res Ther. 2019 Aug 24;10(1):270. doi: 10.1186/s13287-019-1351-5.


A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal.

Grim TW, Schmid CL, Stahl EL, Pantouli F, Ho JH, Acevedo-Canabal A, Kennedy NM, Cameron MD, Bannister TD, Bohn LM.

Neuropsychopharmacology. 2020 Jan;45(2):416-425. doi: 10.1038/s41386-019-0491-8. Epub 2019 Aug 23.


Non-HDL cholesterol should not generally replace LDL cholesterol in the management of hyperlipidaemia.

Soran H, Ho JH, Adam S, Durrington PN.

Curr Opin Lipidol. 2019 Aug;30(4):263-272. doi: 10.1097/MOL.0000000000000614.


Mesenchymal stem cells prolong survival and prevent lethal complications in a porcine model of fulminant liver failure.

Lin NC, Wu HH, Ho JH, Liu CS, Lee OK.

Xenotransplantation. 2019 Nov;26(6):e12542. doi: 10.1111/xen.12542. Epub 2019 Jun 20.


Bariatric surgery as a model to explore the basis and consequences of the Reaven hypothesis: Small, dense low-density lipoprotein and interleukin-6.

Adam S, Liu Y, Siahmansur T, Ho JH, Dhage SS, Yadav R, New JP, Donn R, Ammori BJ, Syed AA, Malik RA, Soran H, Durrington PN.

Diab Vasc Dis Res. 2019 Mar;16(2):144-152. doi: 10.1177/1479164119826479.


The Reaven syndrome: An historical perspective.

Soran H, Adam S, Ho JH, Durrington PN.

Diab Vasc Dis Res. 2019 Mar;16(2):116-117. doi: 10.1177/1479164119828899. No abstract available.


Crystal Structure of the Human Cannabinoid Receptor CB2.

Li X, Hua T, Vemuri K, Ho JH, Wu Y, Wu L, Popov P, Benchama O, Zvonok N, Locke K, Qu L, Han GW, Iyer MR, Cinar R, Coffey NJ, Wang J, Wu M, Katritch V, Zhao S, Kunos G, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ.

Cell. 2019 Jan 24;176(3):459-467.e13. doi: 10.1016/j.cell.2018.12.011. Epub 2019 Jan 10.


First case report of fatal Nocardia nova infection in yellow-bibbed lory (Lorius chlorocercus) identified by multilocus sequencing.

Churgin SM, Teng JLL, Ho JHP, Graydon R, Martelli P, Lee FK, Hui SW, Fong JYH, Lau SKP, Woo PCY.

BMC Vet Res. 2019 Jan 3;15(1):4. doi: 10.1186/s12917-018-1764-x.


Early life stress alters opioid receptor mRNA levels within the nucleus accumbens in a sex-dependent manner.

Chang L, Kigar SL, Ho JH, Cuarenta A, Gunderson HC, Baldo BA, Bakshi VP, Auger AP.

Brain Res. 2019 May 1;1710:102-108. doi: 10.1016/j.brainres.2018.12.040. Epub 2018 Dec 27.


Causes of post-installation penetration of jack-up spudcan foundations in clays.

Li YP, Yang Y, Yi JT, Ho JH, Shi JY, Goh SH, Lee FH.

PLoS One. 2018 Nov 5;13(11):e0206626. doi: 10.1371/journal.pone.0206626. eCollection 2018.


Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization.

Chen WT, Hsu WT, Yen MH, Changou CA, Han CL, Chen YJ, Cheng JY, Chang TH, Lee OK, Ho JH.

Biomaterials. 2019 Jan;190-191:1-10. doi: 10.1016/j.biomaterials.2018.10.026. Epub 2018 Oct 23.


Phytochemical Constituents and Biological Activities of Melicope lunu-ankenda.

Eliaser EM, Ho JH, Hashim NM, Rukayadi Y, Ee GCL, Razis AFA.

Molecules. 2018 Oct 20;23(10). pii: E2708. doi: 10.3390/molecules23102708. Review.


Observing Solid-State Formation of Oriented Porous Functional Oxide Nanowire Heterostructures by in Situ TEM.

Ho JH, Ting YH, Chen JY, Huang CW, Tsai TC, Lin TY, Huang CY, Wu WW.

Nano Lett. 2018 Sep 12;18(9):6064-6070. doi: 10.1021/acs.nanolett.8b03021. Epub 2018 Aug 27.


G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons.

Ho JH, Stahl EL, Schmid CL, Scarry SM, Aubé J, Bohn LM.

Sci Signal. 2018 Aug 7;11(542). pii: eaar4309. doi: 10.1126/scisignal.aar4309.


Early initiation and regular breast milk expression reduces risk of lactogenesis II delay in at-risk Singaporean mothers in a randomised trial.

Fok D, Aris IM, Ho JH, Chan YH, Rauff M, Lui JK, Cregan MD, Hartmann P, Chong YS, Mattar CN.

Singapore Med J. 2019 Feb;60(2):80-88. doi: 10.11622/smedj.2018067. Epub 2018 Jun 7.


Acquired low cholesterol: diagnosis and relevance to safety of low LDL therapeutic targets.

Soran H, Ho JH, Durrington PN.

Curr Opin Lipidol. 2018 Aug;29(4):318-326. doi: 10.1097/MOL.0000000000000526. Review.


Risk Factors for Failure of Direct Current Cardioversion in Patients with Type 2 Diabetes Mellitus and Atrial Fibrillation.

Soran H, Banerjee M, Mohamad JB, Adam S, Ho JH, Ismaeel SM, Dhage S, Syed AA, Abdulla IMA, Younis N, Malik RA.

Biomed Res Int. 2018 Mar 12;2018:5936180. doi: 10.1155/2018/5936180. eCollection 2018.


Hypercholesterolaemia - practical information for non-specialists.

Soran H, Adam S, Mohammad JB, Ho JH, Schofield JD, Kwok S, Siahmansur T, Liu Y, Syed AA, Dhage SS, Stefanutti C, Donn R, Malik RA, Banach M, Durrington PN.

Arch Med Sci. 2018 Jan;14(1):1-21. doi: 10.5114/aoms.2018.72238. Epub 2017 Dec 19.


HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis.

Yan T, Ooi WF, Qamra A, Cheung A, Ma D, Sundaram GM, Xu C, Xing M, Poon L, Wang J, Loh YP, Ho JHJ, Ng JJQ, Ramlee MK, Aswad L, Rozen SG, Ghosh S, Bard FA, Sampath P, Tergaonkar V, Davies JOJ, Hughes JR, Goh E, Bi X, Fullwood MJ, Tan P, Li S.

Nat Commun. 2018 Jan 8;9(1):100. doi: 10.1038/s41467-017-02601-1.


A comparison of the effects of low- and high-dose atorvastatin on lipoprotein metabolism and inflammatory cytokines in type 2 diabetes: Results from the Protection Against Nephropathy in Diabetes with Atorvastatin (PANDA) randomized trial.

Soran H, Liu Y, Adam S, Siahmansur T, Ho JH, Schofield JD, Kwok S, Gittins M, France M, Younis N, Gibson JM, Durrington PN, Rutter MK.

J Clin Lipidol. 2018 Jan - Feb;12(1):44-55. doi: 10.1016/j.jacl.2017.10.011. Epub 2017 Nov 13.


Effect of Roux-en-Y Bariatric Surgery on Lipoproteins, Insulin Resistance, and Systemic and Vascular Inflammation in Obesity and Diabetes.

Yadav R, Hama S, Liu Y, Siahmansur T, Schofield J, Syed AA, France M, Pemberton P, Adam S, Ho JH, Aghamohammadzadeh R, Dhage S, Donn R, Malik RA, New JP, Jeziorska M, Durrington P, Ammori BA, Soran H.

Front Immunol. 2017 Nov 15;8:1512. doi: 10.3389/fimmu.2017.01512. eCollection 2017.


Metal-on-Metal Hip Joint Prostheses: a Retrospective Case Series Investigating the Association of Systemic Toxicity with Serum Cobalt and Chromium Concentrations.

Ho JH, Leikin JB, Dargan PI, Archer JRH, Wood DM, Brent J.

J Med Toxicol. 2017 Dec;13(4):321-328. doi: 10.1007/s13181-017-0629-1. Epub 2017 Sep 12.


Sensitization of Pt/TiO2 Using Plasmonic Au Nanoparticles for Hydrogen Evolution under Visible-Light Irradiation.

Wang F, Wong RJ, Ho JH, Jiang Y, Amal R.

ACS Appl Mater Interfaces. 2017 Sep 13;9(36):30575-30582. doi: 10.1021/acsami.7b06265. Epub 2017 Aug 31.


Ankylosing spondylitis and the risk of cancer.

Chang CC, Chang CW, Nguyen PA, Chang TH, Shih YL, Chang WY, Horng JT, Lee OK, Ho JH.

Oncol Lett. 2017 Aug;14(2):1315-1322. doi: 10.3892/ol.2017.6368. Epub 2017 Jun 9.


Crystal structures of agonist-bound human cannabinoid receptor CB1.

Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, Zhao S, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ.

Nature. 2017 Jul 27;547(7664):468-471. doi: 10.1038/nature23272. Epub 2017 Jul 5.


DNA Methyltransferases Modulate Hepatogenic Lineage Plasticity of Mesenchymal Stromal Cells.

Lee CW, Huang WC, Huang HD, Huang YH, Ho JH, Yang MH, Yang VW, Lee OK.

Stem Cell Reports. 2017 Jul 11;9(1):247-263. doi: 10.1016/j.stemcr.2017.05.008. Epub 2017 Jun 8.


Evidence for more intensive cholesterol lowering.

Soran H, Kwok S, Adam S, Ho JH, Durrington PN.

Curr Opin Lipidol. 2017 Aug;28(4):291-299. doi: 10.1097/MOL.0000000000000433. Review.


Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015.

Abouchedid R, Hudson S, Thurtle N, Yamamoto T, Ho JH, Bailey G, Wood M, Sadones N, Stove CP, Dines A, Archer JRH, Wood DM, Dargan PI.

Clin Toxicol (Phila). 2017 Jun;55(5):338-345. doi: 10.1080/15563650.2017.1287373. Epub 2017 Feb 20.


Treatment of Spinocerebellar Ataxia With Mesenchymal Stem Cells: A Phase I/IIa Clinical Study.

Tsai YA, Liu RS, Lirng JF, Yang BH, Chang CH, Wang YC, Wu YS, Ho JH, Lee OK, Soong BW.

Cell Transplant. 2017 Mar 13;26(3):503-512. doi: 10.3727/096368916X694373. Epub 2017 Feb 14.


Can cost make a difference dosimetrically? Volumetric modulated arc therapy study for multileaf collimators of various widths for head and neck and prostate cancers.

Ho JH, Hagler S, Lujano C, Seng S, Starks C, Perrin K, Turner L, Court L.

Med Dosim. 2017 Spring;42(1):12-17. doi: 10.1016/j.meddos.2016.10.001. Epub 2017 Jan 23.


Crystal Structure of the Human Cannabinoid Receptor CB1.

Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, Kufareva I, Wu B, Zhao Q, Hanson MA, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ.

Cell. 2016 Oct 20;167(3):750-762.e14. doi: 10.1016/j.cell.2016.10.004.


Efficient generation of hepatic cells from mesenchymal stromal cells by an innovative bio-microfluidic cell culture device.

Yen MH, Wu YY, Liu YS, Rimando M, Ho JH, Lee OK.

Stem Cell Res Ther. 2016 Aug 19;7(1):120. doi: 10.1186/s13287-016-0371-7.


Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation.

Abouchedid R, Ho JH, Hudson S, Dines A, Archer JR, Wood DM, Dargan PI.

J Med Toxicol. 2016 Dec;12(4):396-401. Epub 2016 Jul 25.


Nasal dissemination of a single-clone IgH-rearranged conjunctival MALT lymphoma through the nasolacrimal duct: A case report.

Hsieh CY, Liao YP, Wu CC, Yuan SP, Ho JH, Roan R, Liew PL, Lai MT, Lee F.

Oncol Lett. 2016 Aug;12(2):1007-1010. Epub 2016 Jun 10.


Liver Fat Measured by MR Spectroscopy: Estimate of Imprecision and Relationship with Serum Glycerol, Caeruloplasmin and Non-Esterified Fatty Acids.

France M, Kwok S, Soran H, Williams S, Ho JH, Adam S, Canoy D, Liu Y, Durrington PN.

Int J Mol Sci. 2016 Jul 8;17(7). pii: E1089. doi: 10.3390/ijms17071089.


Stromal Tissue Rigidity Promotes Mesenchymal Stem Cell-Mediated Corneal Wound Healing Through the Transforming Growth Factor β Signaling Pathway.

Yang YH, Hsieh TL, Ji AT, Hsu WT, Liu CY, Lee OK, Ho JH.

Stem Cells. 2016 Oct;34(10):2525-2535. doi: 10.1002/stem.2405. Epub 2016 Jun 25.


Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans.

Reis Rodrigues P, Kaul TK, Ho JH, Lucanic M, Burkewitz K, Mair WB, Held JM, Bohn LM, Gill MS.

G3 (Bethesda). 2016 Jun 1;6(6):1695-705. doi: 10.1534/g3.116.026997.


Three-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cells.

Lo YP, Liu YS, Rimando MG, Ho JH, Lin KH, Lee OK.

Sci Rep. 2016 Feb 17;6:21253. doi: 10.1038/srep21253.


Detection of hepatic maturation by Raman spectroscopy in mesenchymal stromal cells undergoing hepatic differentiation.

Wu HH, Ho JH, Lee OK.

Stem Cell Res Ther. 2016 Jan 11;7:6. doi: 10.1186/s13287-015-0259-y.


Availability of prescription zopiclone over the internet.

Ho JH, Wood DM, Archer JR, Dargan PI.

BMJ. 2015 Nov 4;351:h5710. doi: 10.1136/bmj.h5710. No abstract available.


Tuning Phase Composition of TiO2 by Sn(4+) Doping for Efficient Photocatalytic Hydrogen Generation.

Wang F, Ho JH, Jiang Y, Amal R.

ACS Appl Mater Interfaces. 2015 Nov 4;7(43):23941-8. doi: 10.1021/acsami.5b06287. Epub 2015 Oct 21.


Approaches to Assess Functional Selectivity in GPCRs: Evaluating G Protein Signaling in an Endogenous Environment.

Bohn LM, Zhou L, Ho JH.

Methods Mol Biol. 2015;1335:177-89. doi: 10.1007/978-1-4939-2914-6_12.

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