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Items: 13

1.

Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death.

Keuss MJ, Hjerpe R, Hsia O, Gourlay R, Burchmore R, Trost M, Kurz T.

EMBO J. 2019 Mar 15;38(6). pii: e100024. doi: 10.15252/embj.2018100024. Epub 2019 Feb 25.

2.

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osborne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T.

Cell. 2016 Aug 11;166(4):935-949. doi: 10.1016/j.cell.2016.07.001. Epub 2016 Jul 28.

3.

Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity.

Lang V, Pallara C, Zabala A, Lobato-Gil S, Lopitz-Otsoa F, Farrás R, Hjerpe R, Torres-Ramos M, Zabaleta L, Blattner C, Hay RT, Barrio R, Carracedo A, Fernandez-Recio J, Rodríguez MS, Aillet F.

Mol Oncol. 2014 Jul;8(5):1026-42. doi: 10.1016/j.molonc.2014.04.002. Epub 2014 Apr 13.

4.

Heterologous SUMO-2/3-ubiquitin chains optimize IκBα degradation and NF-κB activity.

Aillet F, Lopitz-Otsoa F, Egaña I, Hjerpe R, Fraser P, Hay RT, Rodriguez MS, Lang V.

PLoS One. 2012;7(12):e51672. doi: 10.1371/journal.pone.0051672. Epub 2012 Dec 20.

5.

NEDD8 overexpression results in neddylation of ubiquitin substrates by the ubiquitin pathway.

Hjerpe R, Thomas Y, Kurz T.

J Mol Biol. 2012 Aug 3;421(1):27-9. doi: 10.1016/j.jmb.2012.05.013. Epub 2012 May 15.

6.

Isolation of ubiquitylated proteins using tandem ubiquitin-binding entities.

Aillet F, Lopitz-Otsoa F, Hjerpe R, Torres-Ramos M, Lang V, Rodríguez MS.

Methods Mol Biol. 2012;832:173-83. doi: 10.1007/978-1-61779-474-2_12.

PMID:
22350885
7.

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes.

Hjerpe R, Thomas Y, Chen J, Zemla A, Curran S, Shpiro N, Dick LR, Kurz T.

Biochem J. 2012 Feb 1;441(3):927-36. doi: 10.1042/BJ20111671.

8.

Sumoylation modulates the activity of Spalt-like proteins during wing development in Drosophila.

Sánchez J, Talamillo A, Lopitz-Otsoa F, Pérez C, Hjerpe R, Sutherland JD, Herboso L, Rodríguez MS, Barrio R.

J Biol Chem. 2010 Aug 13;285(33):25841-9. doi: 10.1074/jbc.M110.124024. Epub 2010 Jun 18.

9.

Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation.

Hjerpe R, Aillet F, Lopitz-Otsoa F, Lang V, Torres-Ramos M, Farrás R, Hay RT, Rodríguez MS.

Int J Biochem Cell Biol. 2010 May;42(5):725-35. doi: 10.1016/j.biocel.2010.01.010. Epub 2010 Jan 18.

PMID:
20080206
10.

SUMO and ubiquitin modifications during steroid hormone synthesis and function.

Talamillo A, Martín D, Hjerpe R, Sánchez J, Barrio R.

Biochem Soc Trans. 2010 Feb;38(Pt 1):54-9. doi: 10.1042/BST0380054. Review.

PMID:
20074035
11.

Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities.

Hjerpe R, Aillet F, Lopitz-Otsoa F, Lang V, England P, Rodriguez MS.

EMBO Rep. 2009 Nov;10(11):1250-8. doi: 10.1038/embor.2009.192. Epub 2009 Oct 2.

12.

Efficient approaches for characterizing ubiquitinated proteins.

Hjerpe R, Rodríguez MS.

Biochem Soc Trans. 2008 Oct;36(Pt 5):823-7. doi: 10.1042/BST0360823. Review.

PMID:
18793144
13.

Alternative UPS drug targets upstream the 26S proteasome.

Hjerpe R, Rodríguez MS.

Int J Biochem Cell Biol. 2008;40(6-7):1126-40. doi: 10.1016/j.biocel.2007.11.021. Epub 2007 Dec 8. Review.

PMID:
18203645

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