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Items: 1 to 50 of 90

1.

Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation.

Carpier JM, Zucchetti AE, Bataille L, Dogniaux S, Shafaq-Zadah M, Bardin S, Lucchino M, Maurin M, Joannas LD, Magalhaes JG, Johannes L, Galli T, Goud B, Hivroz C.

J Exp Med. 2018 Apr 2;215(4):1245-1265. doi: 10.1084/jem.20162042. Epub 2018 Feb 12.

2.

Micropipette force probe to quantify single-cell force generation: application to T-cell activation.

Sawicka A, Babataheri A, Dogniaux S, Barakat AI, Gonzalez-Rodriguez D, Hivroz C, Husson J.

Mol Biol Cell. 2017 Nov 7;28(23):3229-3239. doi: 10.1091/mbc.E17-06-0385. Epub 2017 Sep 20.

3.

Different TCR-induced T lymphocyte responses are potentiated by stiffness with variable sensitivity.

Saitakis M, Dogniaux S, Goudot C, Bufi N, Asnacios S, Maurin M, Randriamampita C, Asnacios A, Hivroz C.

Elife. 2017 Jun 8;6. pii: e23190. doi: 10.7554/eLife.23190.

4.

Purification of LAT-Containing Membranes from Resting and Activated T Lymphocytes.

Hivroz C, Larghi P, Jouve M, Ardouin L.

Methods Mol Biol. 2017;1584:355-368. doi: 10.1007/978-1-4939-6881-7_21.

PMID:
28255712
5.

T-lymphocyte passive deformation is controlled by unfolding of membrane surface reservoirs.

Guillou L, Babataheri A, Saitakis M, Bohineust A, Dogniaux S, Hivroz C, Barakat AI, Husson J.

Mol Biol Cell. 2016 Nov 7;27(22):3574-3582. Epub 2016 Sep 7.

6.

PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma.

Beldi-Ferchiou A, Lambert M, Dogniaux S, Vély F, Vivier E, Olive D, Dupuy S, Levasseur F, Zucman D, Lebbé C, Sène D, Hivroz C, Caillat-Zucman S.

Oncotarget. 2016 Nov 8;7(45):72961-72977. doi: 10.18632/oncotarget.12150.

7.

X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) gene.

Lagresle-Peyrou C, Luce S, Ouchani F, Soheili TS, Sadek H, Chouteau M, Durand A, Pic I, Majewski J, Brouzes C, Lambert N, Bohineust A, Verhoeyen E, Cosset FL, Magerus-Chatinet A, Rieux-Laucat F, Gandemer V, Monnier D, Heijmans C, van Gijn M, Dalm VA, Mahlaoui N, Stephan JL, Picard C, Durandy A, Kracker S, Hivroz C, Jabado N, de Saint Basile G, Fischer A, Cavazzana M, André-Schmutz I.

J Allergy Clin Immunol. 2016 Dec;138(6):1681-1689.e8. doi: 10.1016/j.jaci.2016.04.032. Epub 2016 Jun 4.

PMID:
27405666
8.

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing.

Basu R, Whitlock BM, Husson J, Le Floc'h A, Jin W, Oyler-Yaniv A, Dotiwala F, Giannone G, Hivroz C, Biais N, Lieberman J, Kam LC, Huse M.

Cell. 2016 Mar 24;165(1):100-110. doi: 10.1016/j.cell.2016.01.021. Epub 2016 Feb 25.

9.

Biophysical Aspects of T Lymphocyte Activation at the Immune Synapse.

Hivroz C, Saitakis M.

Front Immunol. 2016 Feb 15;7:46. doi: 10.3389/fimmu.2016.00046. eCollection 2016. Review.

10.

IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo.

Vivar OI, Masi G, Carpier JM, Magalhaes JG, Galgano D, Pazour GJ, Amigorena S, Hivroz C, Baldari CT.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):386-91. doi: 10.1073/pnas.1513601113. Epub 2015 Dec 29.

11.

Human Primary Immune Cells Exhibit Distinct Mechanical Properties that Are Modified by Inflammation.

Bufi N, Saitakis M, Dogniaux S, Buschinger O, Bohineust A, Richert A, Maurin M, Hivroz C, Asnacios A.

Biophys J. 2015 May 5;108(9):2181-90. doi: 10.1016/j.bpj.2015.03.047.

12.

Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo.

Clement M, Fornasa G, Loyau S, Morvan M, Andreata F, Guedj K, Khallou-Laschet J, Larghi P, Le Roux D, Bismuth G, Chiocchia G, Hivroz C, Newman DK, Nicoletti A, Caligiuri G.

J Autoimmun. 2015 Jan;56:23-33. doi: 10.1016/j.jaut.2014.09.002. Epub 2014 Sep 30.

PMID:
25277651
13.

MAIT cells detect and efficiently lyse bacterially-infected epithelial cells.

Le Bourhis L, Dusseaux M, Bohineust A, Bessoles S, Martin E, Premel V, Coré M, Sleurs D, Serriari NE, Treiner E, Hivroz C, Sansonetti P, Gougeon ML, Soudais C, Lantz O.

PLoS Pathog. 2013;9(10):e1003681. doi: 10.1371/journal.ppat.1003681. Epub 2013 Oct 10.

14.

VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites.

Larghi P, Williamson DJ, Carpier JM, Dogniaux S, Chemin K, Bohineust A, Danglot L, Gaus K, Galli T, Hivroz C.

Nat Immunol. 2013 Jul;14(7):723-31. doi: 10.1038/ni.2609. Epub 2013 May 12.

PMID:
23666293
15.

Crosstalk between T lymphocytes and dendritic cells.

Hivroz C, Chemin K, Tourret M, Bohineust A.

Crit Rev Immunol. 2012;32(2):139-55. Review.

PMID:
23216612
16.

Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency.

Hauck F, Randriamampita C, Martin E, Gerart S, Lambert N, Lim A, Soulier J, Maciorowski Z, Touzot F, Moshous D, Quartier P, Heritier S, Blanche S, Rieux-Laucat F, Brousse N, Callebaut I, Veillette A, Hivroz C, Fischer A, Latour S, Picard C.

J Allergy Clin Immunol. 2012 Nov;130(5):1144-1152.e11. doi: 10.1016/j.jaci.2012.07.029. Epub 2012 Sep 15.

PMID:
22985903
17.

Cytokine secretion by CD4+ T cells at the immunological synapse requires Cdc42-dependent local actin remodeling but not microtubule organizing center polarity.

Chemin K, Bohineust A, Dogniaux S, Tourret M, Guégan S, Miro F, Hivroz C.

J Immunol. 2012 Sep 1;189(5):2159-68. doi: 10.4049/jimmunol.1200156. Epub 2012 Jul 20.

18.

Biomimetic droplets for artificial engagement of living cell surface receptors: the specific case of the T-cell.

Bourouina N, Husson J, Hivroz C, Henry N.

Langmuir. 2012 Apr 10;28(14):6106-13. doi: 10.1021/la300398a. Epub 2012 Mar 27.

PMID:
22414256
19.

Force generation upon T cell receptor engagement.

Husson J, Chemin K, Bohineust A, Hivroz C, Henry N.

PLoS One. 2011 May 10;6(5):e19680. doi: 10.1371/journal.pone.0019680.

20.

T cell polarity at the immunological synapse is required for CD154-dependent IL-12 secretion by dendritic cells.

Tourret M, Guégan S, Chemin K, Dogniaux S, Miro F, Bohineust A, Hivroz C.

J Immunol. 2010 Dec 1;185(11):6809-18. doi: 10.4049/jimmunol.1001501. Epub 2010 Oct 27.

21.

Early T-cell activation biophysics.

Henry N, Hivroz C.

HFSP J. 2009 Dec;3(6):401-11. doi: 10.2976/1.3254098. Epub 2009 Nov 10.

22.

ZAP70: a master regulator of adaptive immunity.

Fischer A, Picard C, Chemin K, Dogniaux S, le Deist F, Hivroz C.

Semin Immunopathol. 2010 Jun;32(2):107-16. doi: 10.1007/s00281-010-0196-x. Epub 2010 Feb 5. Review.

PMID:
20135127
23.

HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes.

Nobile C, Rudnicka D, Hasan M, Aulner N, Porrot F, Machu C, Renaud O, Prévost MC, Hivroz C, Schwartz O, Sol-Foulon N.

J Virol. 2010 Mar;84(5):2282-93. doi: 10.1128/JVI.02230-09. Epub 2009 Dec 16.

24.

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia.

McCarl CA, Picard C, Khalil S, Kawasaki T, Röther J, Papolos A, Kutok J, Hivroz C, Ledeist F, Plogmann K, Ehl S, Notheis G, Albert MH, Belohradsky BH, Kirschner J, Rao A, Fischer A, Feske S.

J Allergy Clin Immunol. 2009 Dec;124(6):1311-1318.e7. doi: 10.1016/j.jaci.2009.10.007.

25.

Hypomorphic mutation of ZAP70 in human results in a late onset immunodeficiency and no autoimmunity.

Picard C, Dogniaux S, Chemin K, Maciorowski Z, Lim A, Mazerolles F, Rieux-Laucat F, Stolzenberg MC, Debre M, Magny JP, Le Deist F, Fischer A, Hivroz C.

Eur J Immunol. 2009 Jul;39(7):1966-76. doi: 10.1002/eji.200939385.

26.

STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity.

Picard C, McCarl CA, Papolos A, Khalil S, Lüthy K, Hivroz C, LeDeist F, Rieux-Laucat F, Rechavi G, Rao A, Fischer A, Feske S.

N Engl J Med. 2009 May 7;360(19):1971-80. doi: 10.1056/NEJMoa0900082.

27.

T-cell artificial focal triggering tools: linking surface interactions with cell response.

Carpentier B, Pierobon P, Hivroz C, Henry N.

PLoS One. 2009;4(3):e4784. doi: 10.1371/journal.pone.0004784. Epub 2009 Mar 10. Erratum in: PLoS One. 2009;4(9). doi: 10.1371/annotation/d548da9a-692a-4ae9-98ca-92c1ddfa4186.

28.

Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.

Demotte N, Stroobant V, Courtoy PJ, Van Der Smissen P, Colau D, Luescher IF, Hivroz C, Nicaise J, Squifflet JL, Mourad M, Godelaine D, Boon T, van der Bruggen P.

Immunity. 2008 Mar;28(3):414-24. doi: 10.1016/j.immuni.2008.01.011.

29.

Cognate CD4+ T-cell-dendritic cell interactions induce migration of immature dendritic cells through dissolution of their podosomes.

Nobile C, Lind M, Miro F, Chemin K, Tourret M, Occhipinti G, Dogniaux S, Amigorena S, Hivroz C.

Blood. 2008 Apr 1;111(7):3579-90. doi: 10.1182/blood-2007-08-107755. Epub 2008 Jan 18.

30.

[Expression anomalies of the CD3-TCR complex expression and immunodeficiencies].

Le Deist F, de Saint Basile G, Rieux-Laucat F, Hivroz C, Fischer A.

Med Sci (Paris). 2007 Feb;23(2):161-6. Review. French.

31.

ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.

Sol-Foulon N, Sourisseau M, Porrot F, Thoulouze MI, Trouillet C, Nobile C, Blanchet F, di Bartolo V, Noraz N, Taylor N, Alcover A, Hivroz C, Schwartz O.

EMBO J. 2007 Jan 24;26(2):516-26. Epub 2007 Jan 11.

32.

T cell-dependent activation of dendritic cells requires IL-12 and IFN-gamma signaling in T cells.

Miro F, Nobile C, Blanchard N, Lind M, Filipe-Santos O, Fieschi C, Chapgier A, Vogt G, de Beaucoudrey L, Kumararatne DS, Le Deist F, Casanova JL, Amigorena S, Hivroz C.

J Immunol. 2006 Sep 15;177(6):3625-34.

33.
34.

Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells.

Ballerini C, Gourdain P, Bachy V, Blanchard N, Levavasseur E, Grégoire S, Fontes P, Aucouturier P, Hivroz C, Carnaud C.

J Immunol. 2006 Jun 15;176(12):7254-62.

35.

Inherited and somatic CD3zeta mutations in a patient with T-cell deficiency.

Rieux-Laucat F, Hivroz C, Lim A, Mateo V, Pellier I, Selz F, Fischer A, Le Deist F.

N Engl J Med. 2006 May 4;354(18):1913-21.

36.

[Everything you ever wanted to know about ZAP-70].

Hivroz C.

Med Sci (Paris). 2005 Feb;21(2):150-5. Review. French.

37.
38.

[ZAP 70, a kinase indispensible for T lymphocyte activation, implicated in autoimmunity].

Hivroz C.

Med Sci (Paris). 2004 May;20(5):505-6. French. No abstract available.

39.

Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment.

Bonello G, Blanchard N, Montoya MC, Aguado E, Langlet C, He HT, Nunez-Cruz S, Malissen M, Sanchez-Madrid F, Olive D, Hivroz C, Collette Y.

J Cell Sci. 2004 Mar 1;117(Pt 7):1009-16.

40.

Dendritic cell maturation controls adhesion, synapse formation, and the duration of the interactions with naive T lymphocytes.

Benvenuti F, Lagaudrière-Gesbert C, Grandjean I, Jancic C, Hivroz C, Trautmann A, Lantz O, Amigorena S.

J Immunol. 2004 Jan 1;172(1):292-301.

41.

The immunological synapse: the more you look the less you know...

Blanchard N, Hivroz C.

Biol Cell. 2002 Oct;94(6):345-54. Review.

PMID:
12500942
42.

Phosphoinositide 3-kinase activation by Igbeta controls de novo formation of an antigen-processing compartment.

Granboulan M, Lankar D, Raposo G, Bonnerot C, Hivroz C.

J Biol Chem. 2003 Feb 7;278(6):4331-8. Epub 2002 Nov 28.

44.

TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70.

Dumont C, Blanchard N, Di Bartolo V, Lezot N, Dufour E, Jauliac S, Hivroz C.

J Immunol. 2002 Aug 15;169(4):1705-12.

45.

TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.

Blanchard N, Lankar D, Faure F, Regnault A, Dumont C, Raposo G, Hivroz C.

J Immunol. 2002 Apr 1;168(7):3235-41.

46.

[Primary immunodeficiency secondary to ZAP-70 deficiency].

Barata LT, Henriques R, Hivroz C, Jouanguy E, Paiva A, Freitas AM, Coimbra HB, Fischer A, da Mota HC.

Acta Med Port. 2001 Jul-Aug;14(4):413-7. Portuguese.

47.

Herpesvirus saimiri replaces ZAP-70 for CD3- and CD2-mediated T cell activation.

Meinl E, Derfuss T, Pirzer R, Blank N, Lengenfelder D, Blancher A, Le Deist F, Fleckenstein B, Hivroz C.

J Biol Chem. 2001 Oct 5;276(40):36902-8. Epub 2001 Jul 19.

48.

Differential requirement of ZAP-70 for CD2-mediated activation pathways of mature human T cells.

Meinl E, Lengenfelder D, Blank N, Pirzer R, Barata L, Hivroz C.

J Immunol. 2000 Oct 1;165(7):3578-83.

49.

Combined immunodeficiency associated with increased apoptosis of lymphocytes and radiosensitivity fibroblasts.

Peake J, Waugh A, Le Deist F, Priestley A, Rieux-Laucat F, Foray N, Capulas E, Singleton BK, de Villartay JP, Cant A, Malaise EP, Fischer A, Hivroz C, Jeggo PA.

Cancer Res. 1999 Jul 15;59(14):3454-60.

50.

Activation of the Janus kinase 3-STAT5a pathway after CD40 triggering of human monocytes but not of resting B cells.

Revy P, Hivroz C, Andreu G, Graber P, Martinache C, Fischer A, Durandy A.

J Immunol. 1999 Jul 15;163(2):787-93.

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