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Items: 30

1.

Improved outcomes for myeloid leukemia of Down syndrome: a report from the Children's Oncology Group AAML0431 trial.

Taub JW, Berman JN, Hitzler JK, Sorrell AD, Lacayo NJ, Mast K, Head D, Raimondi S, Hirsch B, Ge Y, Gerbing RB, Wang YC, Alonzo TA, Campana D, Coustan-Smith E, Mathew P, Gamis AS.

Blood. 2017 Jun 22;129(25):3304-3313. doi: 10.1182/blood-2017-01-764324. Epub 2017 Apr 7.

2.

Detection of a clone-specific GATA1 mutation to monitor treatment response and involvement of a monozygotic twin in myeloid leukemia of Down syndrome.

Ali S, Ashraf K, Chen J, Hitzler JK.

Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26439. Epub 2017 Jan 11. No abstract available.

PMID:
28074551
3.

Neurocognitive Late Effects of Chemotherapy in Survivors of Acute Lymphoblastic Leukemia: Focus on Methotrexate.

van der Plas E, Nieman BJ, Butcher DT, Hitzler JK, Weksberg R, Ito S, Schachar R.

J Can Acad Child Adolesc Psychiatry. 2015 Winter;24(1):25-32. Epub 2015 Mar 4.

4.

Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

Perova T, Grandal I, Nutter LM, Papp E, Matei IR, Beyene J, Kowalski PE, Hitzler JK, Minden MD, Guidos CJ, Danska JS.

Sci Transl Med. 2014 May 14;6(236):236ra62. doi: 10.1126/scitranslmed.3008661.

5.

Assessment of the outcomes associated with periprocedural anticoagulation management in children with acute lymphoblastic leukemia.

Avila ML, Macartney CA, Hitzler JK, Williams S, Kiss A, Brandão LR.

J Pediatr. 2014 May;164(5):1201-7. doi: 10.1016/j.jpeds.2014.01.031. Epub 2014 Feb 25.

PMID:
24582006
6.

Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome.

Hitzler JK, He W, Doyle J, Cairo M, Camitta BM, Chan KW, Diaz Perez MA, Fraser C, Gross TG, Horan JT, Kennedy-Nasser AA, Kitko C, Kurtzberg J, Lehmann L, O'Brien T, Pulsipher MA, Smith FO, Zhang MJ, Eapen M, Carpenter PA; CIBMTR Pediatric Cancer Working Committee.

Pediatr Blood Cancer. 2014 Jun;61(6):1126-8. doi: 10.1002/pbc.24918. Epub 2014 Jan 4.

7.

Outcome of transplantation for acute myelogenous leukemia in children with Down syndrome.

Hitzler JK, He W, Doyle J, Cairo M, Camitta BM, Chan KW, Diaz Perez MA, Fraser C, Gross TG, Horan JT, Kennedy-Nasser AA, Kitko C, Kurtzberg J, Lehmann L, O'Brien T, Pulsipher MA, Smith FO, Zhang MJ, Eapen M, Carpenter PA; CIBMTR Pediatric Cancer Working Committee.

Biol Blood Marrow Transplant. 2013 Jun;19(6):893-7. doi: 10.1016/j.bbmt.2013.02.017. Epub 2013 Mar 1.

8.

Transient leukemia in newborns without down syndrome: diagnostic and management challenges.

Williams BA, Meyn MS, Hitzler JK.

J Pediatr Hematol Oncol. 2011 Aug;33(6):e261-3. doi: 10.1097/MPH.0b013e3182159f4e.

PMID:
21768885
9.

Functional differences between myeloid leukemia-initiating and transient leukemia cells in Down's syndrome.

Chen J, Li Y, Doedens M, Wang P, Shago M, Dick JE, Hitzler JK.

Leukemia. 2010 May;24(5):1012-7. doi: 10.1038/leu.2010.30. Epub 2010 Mar 11. Erratum in: Leukemia. 2010 Aug;24(8):1542. Dick, J [corrected to Dick, J E].

PMID:
20220775
10.

Acute megakaryoblastic leukemia in Down syndrome.

Hitzler JK.

Pediatr Blood Cancer. 2007 Dec;49(7 Suppl):1066-9. Review.

PMID:
17943965
11.

Comparison of long-term neurocognitive outcomes in young children with acute lymphoblastic leukemia treated with cranial radiation or high-dose or very high-dose intravenous methotrexate.

Spiegler BJ, Kennedy K, Maze R, Greenberg ML, Weitzman S, Hitzler JK, Nathan PC.

J Clin Oncol. 2006 Aug 20;24(24):3858-64. Erratum in: J Clin Oncol. 2006 Nov 10;24(32):5181.

PMID:
16921038
12.

Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function.

Sun Y, Boyd K, Xu W, Ma J, Jackson CW, Fu A, Shillingford JM, Robinson GW, Hennighausen L, Hitzler JK, Ma Z, Morris SW.

Mol Cell Biol. 2006 Aug;26(15):5809-26.

13.

RBM15 and MKL1 mutational screening in megakaryoblastic leukemia cell lines and clinical samples.

Kawaguchi H, Hitzler JK, Ma Z, Morris SW.

Leukemia. 2005 Aug;19(8):1492-4. No abstract available.

PMID:
15920491
14.

A basic classification and a comprehensive examination of pediatric myeloproliferative syndromes.

Gassas A, Doyle JJ, Weitzman S, Freedman MH, Hitzler JK, Sharathkumar A, Dror Y.

J Pediatr Hematol Oncol. 2005 Apr;27(4):192-6.

PMID:
15838389
15.

Origins of leukaemia in children with Down syndrome.

Hitzler JK, Zipursky A.

Nat Rev Cancer. 2005 Jan;5(1):11-20. Review.

PMID:
15630411
16.

Distinct gene signatures of transient and acute megakaryoblastic leukemia in Down syndrome.

Lightfoot J, Hitzler JK, Zipursky A, Albert M, Macgregor PF.

Leukemia. 2004 Oct;18(10):1617-23.

PMID:
15343346
17.

cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP.

Hanissian SH, Akbar U, Teng B, Janjetovic Z, Hoffmann A, Hitzler JK, Iscove N, Hamre K, Du X, Tong Y, Mukatira S, Robertson JH, Morris SW.

Oncogene. 2004 Apr 29;23(20):3700-7.

PMID:
15116101
18.

CNS-directed therapy in young children with T-lineage acute lymphoblastic leukemia: High-dose methotrexate versus cranial irradiation.

Nathan PC, Maze R, Spiegler B, Greenberg ML, Weitzman S, Hitzler JK.

Pediatr Blood Cancer. 2004 Jan;42(1):24-9.

PMID:
14752790
19.

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes.

Cen B, Selvaraj A, Burgess RC, Hitzler JK, Ma Z, Morris SW, Prywes R.

Mol Cell Biol. 2003 Sep;23(18):6597-608.

20.

GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome.

Hitzler JK, Cheung J, Li Y, Scherer SW, Zipursky A.

Blood. 2003 Jun 1;101(11):4301-4. Epub 2003 Feb 13.

21.

GATA1--a player in normal and leukemic megakaryopoiesis.

Hitzler JK.

Pediatr Res. 2002 Dec;52(6):831. No abstract available.

PMID:
12438656
22.

Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.

Inoue A, Seidel MG, Wu W, Kamizono S, Ferrando AA, Bronson RT, Iwasaki H, Akashi K, Morimoto A, Hitzler JK, Pestina TI, Jackson CW, Tanaka R, Chong MJ, McKinnon PJ, Inukai T, Grosveld GC, Look AT.

Cancer Cell. 2002 Oct;2(4):279-88.

23.
25.

Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.

Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X, Bouman D, Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GC, Chan LC, Squire J, Scherer SW, Hitzler JK.

Nat Genet. 2001 Jul;28(3):220-1.

PMID:
11431691
26.

cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia.

Hitzler JK, Witte DP, Jenkins NA, Copeland NG, Gilbert DJ, Naeve CW, Look AT, Morris SW.

Am J Pathol. 1999 Jul;155(1):53-9.

27.

Expression patterns of the hepatic leukemia factor gene in the nervous system of developing and adult mice.

Hitzler JK, Soares HD, Drolet DW, Inaba T, O'Connel S, MG Rosenfeld, Morgan JI, Look AT.

Brain Res. 1999 Feb 27;820(1-2):1-11.

PMID:
10023025
28.

Juvenile chronic myelogenous leukemia multilineage CD34+ cells: aberrant growth and differentiation properties.

Freedman MH, Hitzler JK, Bunin N, Grunberger T, Squire J.

Stem Cells. 1996 Nov;14(6):690-701.

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