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Items: 1 to 50 of 79

1.

Clinical decisions following implementation of asparaginase activity monitoring in pediatric patients with acute lymphoblastic leukemia: Experience from a single-center study.

Nadeem K, Colantonio D, Kircanski I, Naqvi A, Hitzler J, Whitlock JA, Dupuis LL.

Pediatr Blood Cancer. 2019 Oct 18:e28044. doi: 10.1002/pbc.28044. [Epub ahead of print]

PMID:
31625674
2.

Asymptomatic Pulmonary Artery Embolization by a Port-a-Cath Fragment in a Child With Acute Lymphoblastic Leukemia.

Tandon S, Livingston J, Krishnamurthy G, Hitzler J, Punnett A.

J Pediatr Hematol Oncol. 2019 Nov;41(8):618-619. doi: 10.1097/MPH.0000000000001590.

PMID:
31568182
3.

Pathologic Features of Down Syndrome Myelodysplastic Syndrome and Acute Myeloid Leukemia: A Report From the Children's Oncology Group Protocol AAML0431.

Mast KJ, Taub JW, Alonzo TA, Gamis AS, Mosse CA, Mathew P, Berman JN, Wang YC, Jones HM, Campana D, Coustan-Smith E, Raimondi SC, Hirsch B, Hitzler JK, Head DR.

Arch Pathol Lab Med. 2019 Aug 20. doi: 10.5858/arpa.2018-0526-OA. [Epub ahead of print]

PMID:
31429606
4.

Excellent long-term survival of children with Down syndrome and standard-risk ALL: a report from the Children's Oncology Group.

Matloub Y, Rabin KR, Ji L, Devidas M, Hitzler J, Xu X, Bostrom BC, Stork LC, Winick N, Gastier-Foster JM, Heerema NA, Stonerock E, Carroll WL, Hunger SP, Gaynon PS.

Blood Adv. 2019 Jun 11;3(11):1647-1656. doi: 10.1182/bloodadvances.2019032094.

5.

Unusual lymphoid malignancy and treatment response in two children with Down syndrome.

Geerlinks A, Keis J, Ngan B, Shammas A, Vali R, Hitzler J.

Pediatr Blood Cancer. 2019 Sep;66(9):e27822. doi: 10.1002/pbc.27822. Epub 2019 May 28.

PMID:
31136091
6.

Need for new thinking: Treatment of relapsed leukemia in children with Down syndrome.

Rabin K, Izraeli S, Hijiya N, Hitzler J.

Pediatr Blood Cancer. 2019 Jun;66(6):e27644. doi: 10.1002/pbc.27644. Epub 2019 Feb 5. No abstract available.

PMID:
30724029
7.

Gemtuzumab ozogamicin in acute myeloid leukemia: act 2, with perhaps more to come.

Hitzler J, Estey E.

Haematologica. 2019 Jan;104(1):7-9. doi: 10.3324/haematol.2018.205948. No abstract available.

8.

Brain Development and Heart Function after Systemic Single-Agent Chemotherapy in a Mouse Model of Childhood Leukemia Treatment.

Spencer Noakes TL, Przybycien TS, Forwell A, Nicholls C, Zhou YQ, Butcher DT, Weksberg R, Guger SL, Spiegler BJ, Schachar RJ, Hitzler J, Ito S, van der Plas E, Nieman BJ.

Clin Cancer Res. 2018 Dec 1;24(23):6040-6052. doi: 10.1158/1078-0432.CCR-18-0551. Epub 2018 Jul 27.

PMID:
30054283
9.

Characterizing neurocognitive late effects in childhood leukemia survivors using a combination of neuropsychological and cognitive neuroscience measures.

Van Der Plas E, Erdman L, Nieman BJ, Weksberg R, Butcher DT, O'connor DL, Aufreiter S, Hitzler J, Guger SL, Schachar RJ, Ito S, Spiegler BJ.

Child Neuropsychol. 2018 Nov;24(8):999-1014. doi: 10.1080/09297049.2017.1386170. Epub 2017 Oct 10.

PMID:
29017430
10.

Value of flow cytometric analysis of peripheral blood samples in children diagnosed with acute lymphoblastic leukemia.

Lam G, Punnett A, Stephens D, Sung L, Abdelhaleem M, Hitzler J.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26738. Epub 2017 Aug 2.

PMID:
28766841
11.

Predictors of thrombohemorrhagic early death in children and adolescents with t(15;17)-positive acute promyelocytic leukemia treated with ATRA and chemotherapy.

Abla O, Ribeiro RC, Testi AM, Montesinos P, Creutzig U, Sung L, Di Giuseppe G, Stephens D, Feusner JH, Powell BL, Hasle H, Kaspers GJL, Dalla-Pozza L, Lassaletta A, Tallman MS, Locatelli F, Reinhardt D, Lo-Coco F, Hitzler J, Sanz MA.

Ann Hematol. 2017 Sep;96(9):1449-1456. doi: 10.1007/s00277-017-3042-6. Epub 2017 Jun 8.

PMID:
28597167
12.

Improved outcomes for myeloid leukemia of Down syndrome: a report from the Children's Oncology Group AAML0431 trial.

Taub JW, Berman JN, Hitzler JK, Sorrell AD, Lacayo NJ, Mast K, Head D, Raimondi S, Hirsch B, Ge Y, Gerbing RB, Wang YC, Alonzo TA, Campana D, Coustan-Smith E, Mathew P, Gamis AS.

Blood. 2017 Jun 22;129(25):3304-3313. doi: 10.1182/blood-2017-01-764324. Epub 2017 Apr 7.

13.

Brain structure, working memory and response inhibition in childhood leukemia survivors.

van der Plas E, Schachar RJ, Hitzler J, Crosbie J, Guger SL, Spiegler BJ, Ito S, Nieman BJ.

Brain Behav. 2016 Dec 29;7(2):e00621. doi: 10.1002/brb3.621. eCollection 2017 Feb.

14.

Detection of a clone-specific GATA1 mutation to monitor treatment response and involvement of a monozygotic twin in myeloid leukemia of Down syndrome.

Ali S, Ashraf K, Chen J, Hitzler JK.

Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26439. Epub 2017 Jan 11. No abstract available.

PMID:
28074551
15.

Clinical presentation and risk factors of serious infections in children with Down syndrome treated for acute lymphoblastic leukemia.

Ceppi F, Stephens D, den Hollander BS, Krueger J, Whitlock J, Sung L, Hitzler J.

Pediatr Blood Cancer. 2016 Nov;63(11):1949-53. doi: 10.1002/pbc.26127. Epub 2016 Jul 11.

PMID:
27399585
16.

Frequency and outcome of pediatric acute lymphoblastic leukemia with ZNF384 gene rearrangements including a novel translocation resulting in an ARID1B/ZNF384 gene fusion.

Shago M, Abla O, Hitzler J, Weitzman S, Abdelhaleem M.

Pediatr Blood Cancer. 2016 Nov;63(11):1915-21. doi: 10.1002/pbc.26116. Epub 2016 Jul 8.

PMID:
27392123
17.

Minimal Residual Disease and Childhood Leukemia: Standard of Care Recommendations From the Pediatric Oncology Group of Ontario MRD Working Group.

Athale UH, Gibson PJ, Bradley NM, Malkin DM, Hitzler J; POGO MRD Working Group.

Pediatr Blood Cancer. 2016 Jun;63(6):973-82. doi: 10.1002/pbc.25939. Epub 2016 Feb 23. Review.

PMID:
26914030
18.

Early Complications of Hyperleukocytosis and Leukapheresis in Childhood Acute Leukemias.

Abla O, Angelini P, Di Giuseppe G, Kanani MF, Lau W, Hitzler J, Sung L, Naqvi A.

J Pediatr Hematol Oncol. 2016 Mar;38(2):111-7. doi: 10.1097/MPH.0000000000000490.

PMID:
26794706
19.

Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia.

Stieglitz E, Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T, Esquivel E, Yu A, Seepo S, Olsen SR, Rosenberg M, Archambeault SL, Abusin G, Beckman K, Brown PA, Briones M, Carcamo B, Cooper T, Dahl GV, Emanuel PD, Fluchel MN, Goyal RK, Hayashi RJ, Hitzler J, Hugge C, Liu YL, Messinger YH, Mahoney DH Jr, Monteleone P, Nemecek ER, Roehrs PA, Schore RJ, Stine KC, Takemoto CM, Toretsky JA, Costello JF, Olshen AB, Stewart C, Li Y, Ma J, Gerbing RB, Alonzo TA, Getz G, Gruber TA, Golub TR, Stegmaier K, Loh ML.

Nat Genet. 2016 Jan;48(1):101. doi: 10.1038/ng0116-101a. No abstract available.

PMID:
26711114
20.

The genomic landscape of juvenile myelomonocytic leukemia.

Stieglitz E, Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T, Esquivel E, Yu A, Seepo S, Olsen S, Rosenberg M, Archambeault SL, Abusin G, Beckman K, Brown PA, Briones M, Carcamo B, Cooper T, Dahl GV, Emanuel PD, Fluchel MN, Goyal RK, Hayashi RJ, Hitzler J, Hugge C, Liu YL, Messinger YH, Mahoney DH Jr, Monteleone P, Nemecek ER, Roehrs PA, Schore RJ, Stine KC, Takemoto CM, Toretsky JA, Costello JF, Olshen AB, Stewart C, Li Y, Ma J, Gerbing RB, Alonzo TA, Getz G, Gruber T, Golub T, Stegmaier K, Loh ML.

Nat Genet. 2015 Nov;47(11):1326-1333. doi: 10.1038/ng.3400. Epub 2015 Oct 12. Erratum in: Nat Genet. 2015 Nov;47(11):1333. Nat Genet. 2016 Jan;48(1):101.

21.

Neurocognitive Late Effects of Chemotherapy in Survivors of Acute Lymphoblastic Leukemia: Focus on Methotrexate.

van der Plas E, Nieman BJ, Butcher DT, Hitzler JK, Weksberg R, Ito S, Schachar R.

J Can Acad Child Adolesc Psychiatry. 2015 Winter;24(1):25-32. Epub 2015 Mar 4.

22.

Combined Yamamoto approach for simultaneous estimation of adsorption isotherm and kinetic parameters in ion-exchange chromatography.

Rüdt M, Gillet F, Heege S, Hitzler J, Kalbfuss B, Guélat B.

J Chromatogr A. 2015 Sep 25;1413:68-76. doi: 10.1016/j.chroma.2015.08.025. Epub 2015 Aug 17.

PMID:
26306913
23.

Pre-Morbid Developmental Vulnerabilities in Children With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL).

Janzen LA, David D, Walker D, Hitzler J, Zupanec S, Jones H, Spiegler BJ.

Pediatr Blood Cancer. 2015 Dec;62(12):2183-8. doi: 10.1002/pbc.25692. Epub 2015 Aug 25.

PMID:
26305495
24.

Treatment of young children with CNS-positive acute lymphoblastic leukemia without cranial radiotherapy.

Wilejto M, Di Giuseppe G, Hitzler J, Gupta S, Abla O.

Pediatr Blood Cancer. 2015 Nov;62(11):1881-5. doi: 10.1002/pbc.25620. Epub 2015 Jul 7.

PMID:
26154757
25.

Neuropsychological late effects of treatment for acute leukemia in children with Down syndrome.

Roncadin C, Hitzler J, Downie A, Montour-Proulx I, Alyman C, Cairney E, Spiegler BJ.

Pediatr Blood Cancer. 2015 May;62(5):854-8. doi: 10.1002/pbc.25362. Epub 2014 Dec 24.

PMID:
25545182
26.

Diagnosis of central nervous system relapse of pediatric acute lymphoblastic leukemia: Impact of routine cytological CSF analysis at the time of intrathecal chemotherapy.

Gassas A, Krueger J, Alvi S, Sung L, Hitzler J, Lieberman L.

Pediatr Blood Cancer. 2014 Dec;61(12):2215-7. doi: 10.1002/pbc.25235. Epub 2014 Sep 11.

PMID:
25212396
27.

The outcome of allogeneic hematopoietic cell transplantation for children with FMS-like tyrosine kinase 3 internal tandem duplication-positive acute myelogenous leukemia.

Schechter T, Gassas A, Chen H, Pollard J, Meshinchi S, Zaidman I, Hitzler J, Abdelhaleem M, Ho R, Domm J, Woolfrey A, Frangoul H.

Biol Blood Marrow Transplant. 2015 Jan;21(1):172-5. doi: 10.1016/j.bbmt.2014.08.008. Epub 2014 Aug 16.

28.

Risk of late effects of treatment in children newly diagnosed with standard-risk acute lymphoblastic leukaemia: a report from the Childhood Cancer Survivor Study cohort.

Essig S, Li Q, Chen Y, Hitzler J, Leisenring W, Greenberg M, Sklar C, Hudson MM, Armstrong GT, Krull KR, Neglia JP, Oeffinger KC, Robison LL, Kuehni CE, Yasui Y, Nathan PC.

Lancet Oncol. 2014 Jul;15(8):841-51. doi: 10.1016/S1470-2045(14)70265-7. Epub 2014 Jun 19.

29.

Transient myeloproliferative disorder in neonates without Down syndrome: case report and review.

Schifferli A, Hitzler J, Bartholdi D, Heinimann K, Hoeller S, Diesch T, Kühne T.

Eur J Haematol. 2015 May;94(5):456-62. doi: 10.1111/ejh.12382. Epub 2014 Jun 14.

PMID:
24853125
30.

Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

Perova T, Grandal I, Nutter LM, Papp E, Matei IR, Beyene J, Kowalski PE, Hitzler JK, Minden MD, Guidos CJ, Danska JS.

Sci Transl Med. 2014 May 14;6(236):236ra62. doi: 10.1126/scitranslmed.3008661.

31.

Assessment of the outcomes associated with periprocedural anticoagulation management in children with acute lymphoblastic leukemia.

Avila ML, Macartney CA, Hitzler JK, Williams S, Kiss A, Brandão LR.

J Pediatr. 2014 May;164(5):1201-7. doi: 10.1016/j.jpeds.2014.01.031. Epub 2014 Feb 25.

PMID:
24582006
32.

Leukapheresis and low-dose chemotherapy do not reduce early mortality in acute myeloid leukemia hyperleukocytosis: a systematic review and meta-analysis.

Oberoi S, Lehrnbecher T, Phillips B, Hitzler J, Ethier MC, Beyene J, Sung L.

Leuk Res. 2014 Apr;38(4):460-8. doi: 10.1016/j.leukres.2014.01.004. Epub 2014 Jan 10. Review.

PMID:
24472688
33.

Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome.

Hitzler JK, He W, Doyle J, Cairo M, Camitta BM, Chan KW, Diaz Perez MA, Fraser C, Gross TG, Horan JT, Kennedy-Nasser AA, Kitko C, Kurtzberg J, Lehmann L, O'Brien T, Pulsipher MA, Smith FO, Zhang MJ, Eapen M, Carpenter PA; CIBMTR Pediatric Cancer Working Committee.

Pediatr Blood Cancer. 2014 Jun;61(6):1126-8. doi: 10.1002/pbc.24918. Epub 2014 Jan 4.

34.

GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia.

Maroz A, Stachorski L, Emmrich S, Reinhardt K, Xu J, Shao Z, Käbler S, Dertmann T, Hitzler J, Roberts I, Vyas P, Juban G, Hennig C, Hansen G, Li Z, Orkin S, Reinhardt D, Klusmann JH.

Leukemia. 2014 Jun;28(6):1259-70. doi: 10.1038/leu.2013.373. Epub 2013 Dec 13.

35.

Infections in children with down syndrome and acute myeloid leukemia: a report from the Canadian infections in AML research group.

Tran TH, Mitchell D, Dix D, Cellot S, Ethier MC, Gillmeister B, Hitzler J, Lewis V, Yanofsky R, Johnston DL, Portwine C, Price V, Zelcer S, Silva M, Michon B, Bowes L, Stobart K, Brossard J, Beyene J, Sung L.

Infect Agent Cancer. 2013 Dec 2;8(1):47. doi: 10.1186/1750-9378-8-47.

36.

Use of allogeneic hematopoietic stem-cell transplantation based on minimal residual disease response improves outcomes for children with relapsed acute lymphoblastic leukemia in the intermediate-risk group.

Eckert C, Henze G, Seeger K, Hagedorn N, Mann G, Panzer-Grümayer R, Peters C, Klingebiel T, Borkhardt A, Schrappe M, Schrauder A, Escherich G, Sramkova L, Niggli F, Hitzler J, von Stackelberg A.

J Clin Oncol. 2013 Jul 20;31(21):2736-42. doi: 10.1200/JCO.2012.48.5680. Epub 2013 Jun 17.

PMID:
23775972
37.

Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.

Castelo-Branco P, Choufani S, Mack S, Gallagher D, Zhang C, Lipman T, Zhukova N, Walker EJ, Martin D, Merino D, Wasserman JD, Elizabeth C, Alon N, Zhang L, Hovestadt V, Kool M, Jones DT, Zadeh G, Croul S, Hawkins C, Hitzler J, Wang JC, Baruchel S, Dirks PB, Malkin D, Pfister S, Taylor MD, Weksberg R, Tabori U.

Lancet Oncol. 2013 May;14(6):534-42. doi: 10.1016/S1470-2045(13)70110-4. Epub 2013 Apr 16.

PMID:
23598174
38.

Outcomes of treatment for relapsed acute lymphoblastic leukaemia in children with Down syndrome.

Meyr F, Escherich G, Mann G, Klingebiel T, Kulozik A, Rossig C, Schrappe M, Henze G, von Stackelberg A, Hitzler J.

Br J Haematol. 2013 Jul;162(1):98-106. doi: 10.1111/bjh.12348. Epub 2013 Apr 18.

PMID:
23594030
39.

Outcome of transplantation for acute myelogenous leukemia in children with Down syndrome.

Hitzler JK, He W, Doyle J, Cairo M, Camitta BM, Chan KW, Diaz Perez MA, Fraser C, Gross TG, Horan JT, Kennedy-Nasser AA, Kitko C, Kurtzberg J, Lehmann L, O'Brien T, Pulsipher MA, Smith FO, Zhang MJ, Eapen M, Carpenter PA; CIBMTR Pediatric Cancer Working Committee.

Biol Blood Marrow Transplant. 2013 Jun;19(6):893-7. doi: 10.1016/j.bbmt.2013.02.017. Epub 2013 Mar 1.

40.

Transient leukemia in newborns without down syndrome: diagnostic and management challenges.

Williams BA, Meyn MS, Hitzler JK.

J Pediatr Hematol Oncol. 2011 Aug;33(6):e261-3. doi: 10.1097/MPH.0b013e3182159f4e.

PMID:
21768885
41.

Dexamethasone versus prednisone for induction therapy in childhood acute lymphoblastic leukemia: a systematic review and meta-analysis.

Teuffel O, Kuster SP, Hunger SP, Conter V, Hitzler J, Ethier MC, Shah PS, Beyene J, Sung L.

Leukemia. 2011 Aug;25(8):1232-8. doi: 10.1038/leu.2011.84. Epub 2011 Apr 29. Review.

PMID:
21527934
42.

Functional differences between myeloid leukemia-initiating and transient leukemia cells in Down's syndrome.

Chen J, Li Y, Doedens M, Wang P, Shago M, Dick JE, Hitzler JK.

Leukemia. 2010 May;24(5):1012-7. doi: 10.1038/leu.2010.30. Epub 2010 Mar 11. Erratum in: Leukemia. 2010 Aug;24(8):1542. Dick, J [corrected to Dick, J E].

PMID:
20220775
43.

Acute leukemias in children with Down syndrome.

Zwaan CM, Reinhardt D, Hitzler J, Vyas P.

Hematol Oncol Clin North Am. 2010 Feb;24(1):19-34. doi: 10.1016/j.hoc.2009.11.009. Review.

PMID:
20113894
44.

Outcome and toxicity of chemotherapy for acute lymphoblastic leukemia in children with Down syndrome.

Shah N, Al-Ahmari A, Al-Yamani A, Dupuis L, Stephens D, Hitzler J.

Pediatr Blood Cancer. 2009 Jan;52(1):14-9. doi: 10.1002/pbc.21737.

PMID:
18802938
45.

Lumbar spinal fluid collections in children treated with intrathecal chemotherapy: elevated CSF protein as a diagnostic clue.

Almanjomi F, Armstrong D, Abla O, Naqvi A, Weitzman S, Hitzler J.

Pediatr Blood Cancer. 2008 Aug;51(2):295-8. doi: 10.1002/pbc.21592.

PMID:
18454469
46.

Cost-utility analysis of Canadian tailored prophylaxis, primary prophylaxis and on-demand therapy in young children with severe haemophilia A.

Risebrough N, Oh P, Blanchette V, Curtin J, Hitzler J, Feldman BM.

Haemophilia. 2008 Jul;14(4):743-52. doi: 10.1111/j.1365-2516.2008.01664.x. Epub 2008 Apr 16.

PMID:
18422610
47.

Isolated central nervous system relapse in childhood acute promyelocytic leukemia.

Scheinemann K, Weitzman S, Hitzler J, Doyle J, Abla O.

J Pediatr Hematol Oncol. 2008 Feb;30(2):160-2. doi: 10.1097/MPH.0b013e318159a582.

PMID:
18376270
48.

Acute leukemias in children with Down syndrome.

Zwaan MC, Reinhardt D, Hitzler J, Vyas P.

Pediatr Clin North Am. 2008 Feb;55(1):53-70, x. doi: 10.1016/j.pcl.2007.11.001. Review.

PMID:
18242315
49.

Acute megakaryoblastic leukemia in Down syndrome.

Hitzler JK.

Pediatr Blood Cancer. 2007 Dec;49(7 Suppl):1066-9. Review.

PMID:
17943965
50.

Features at presentation predict children with acute lymphoblastic leukemia at low risk for tumor lysis syndrome.

Truong TH, Beyene J, Hitzler J, Abla O, Maloney AM, Weitzman S, Sung L.

Cancer. 2007 Oct 15;110(8):1832-9.

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