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[Subcapsular hepatic hematoma due to vessel injury from the rigid portion of a guidewire during endoscopic retrograde cholangiopancreatography].

Kawakatsu Y, Inoue N, Okazaki Y, Hitomi M, Kawabata H, Miyata M, Motoi S.

Nihon Shokakibyo Gakkai Zasshi. 2018;115(10):898-904. doi: 10.11405/nisshoshi.115.898. Japanese.


Endoscopic closure of an anastomo-cutaneous fistula: Filling and shielding using polyglycolic acid sheets and fibrin glue with easily deliverable technique.

Kawabata H, Okazaki Y, Inoue N, Kawakatsu Y, Hitomi M, Miyata M, Motoi S.

Endosc Int Open. 2018 Aug;6(8):E994-E997. doi: 10.1055/a-0584-6669. Epub 2018 Aug 3.


Effects of the angiotensin-converting enzyme inhibitor alacepril in dogs with mitral valve disease.

Hori Y, Nakamura K, Kanno N, Hitomi M, Yamashita Y, Hosaka S, Isayama N, Mimura T.

J Vet Med Sci. 2018 Aug 10;80(8):1212-1218. doi: 10.1292/jvms.17-0557. Epub 2018 Jun 22.


[Screening for colorectal cancer using immunological fecal occult blood test in inpatients].

Kawabata H, Inoue N, Kawakatsu Y, Okazaki Y, Hitomi M, Miyata M, Motoi S.

Nihon Shokakibyo Gakkai Zasshi. 2018;115(4):377-384. doi: 10.11405/nisshoshi.115.377. Japanese.


Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase.

Thiagarajan PS, Sinyuk M, Turaga SM, Mulkearns-Hubert EE, Hale JS, Rao V, Demelash A, Saygin C, China A, Alban TJ, Hitomi M, Torre-Healy LA, Alvarado AG, Jarrar A, Wiechert A, Adorno-Cruz V, Fox PL, Calhoun BC, Guan JL, Liu H, Reizes O, Lathia JD.

Nat Commun. 2018 Feb 8;9(1):578. doi: 10.1038/s41467-018-02938-1.


New Advances and Challenges of Targeting Cancer Stem Cells.

Dashzeveg NK, Taftaf R, Ramos EK, Torre-Healy L, Chumakova A, Silver DJ, Alban TJ, Sinyuk M, Thiagarajan PS, Jarrar AM, Turaga SM, Saygin C, Mulkearns-Hubert E, Hitomi M, Rich JN, Gerson SL, Lathia JD, Liu H.

Cancer Res. 2017 Oct 1;77(19):5222-5227. doi: 10.1158/0008-5472.CAN-17-0054. Epub 2017 Sep 19.


Intraductal Ultrasonography as a Local Assessment Before Magnetic Compression Anastomosis for Obstructed Choledochojejunostomy.

Kawabata H, Hitomi M, Inoue N, Kawakatsu Y, Okazaki Y, Miyata M.

Gastroenterology Res. 2017 Aug;10(4):255-258. doi: 10.14740/gr842w. Epub 2017 Aug 31.


Varied Reports of Adult Transgender Suicidality: Synthesizing and Describing the Peer-Reviewed and Gray Literature.

Adams N, Hitomi M, Moody C.

Transgend Health. 2017 Apr 1;2(1):60-75. doi: 10.1089/trgh.2016.0036. eCollection 2017. Review.


Cisplatin induces stemness in ovarian cancer.

Wiechert A, Saygin C, Thiagarajan PS, Rao VS, Hale JS, Gupta N, Hitomi M, Nagaraj AB, DiFeo A, Lathia JD, Reizes O.

Oncotarget. 2016 May 24;7(21):30511-22. doi: 10.18632/oncotarget.8852.


Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.

Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M.

Cancer Res. 2016 Apr 15;76(8):2432-42. doi: 10.1158/0008-5472.CAN-15-2162. Epub 2016 Feb 26.


Cx25 contributes to leukemia cell communication and chemosensitivity.

Sinyuk M, Alvarado AG, Nesmiyanov P, Shaw J, Mulkearns-Hubert EE, Eurich JT, Hale JS, Bogdanova A, Hitomi M, Maciejewski J, Huang AY, Saunthararajah Y, Lathia JD.

Oncotarget. 2015 Oct 13;6(31):31508-21. doi: 10.18632/oncotarget.5226.


Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration.

Zhang A, Hitomi M, Bar-Shain N, Dalimov Z, Ellis L, Velpula KK, Fraizer GC, Gourdie RG, Lathia JD.

Oncotarget. 2015 May 10;6(13):11640-51.


Differential connexin function enhances self-renewal in glioblastoma.

Hitomi M, Deleyrolle LP, Mulkearns-Hubert EE, Jarrar A, Li M, Sinyuk M, Otvos B, Brunet S, Flavahan WA, Hubert CG, Goan W, Hale JS, Alvarado AG, Zhang A, Rohaus M, Oli M, Vedam-Mai V, Fortin JM, Futch HS, Griffith B, Wu Q, Xia CH, Gong X, Ahluwalia MS, Rich JN, Reynolds BA, Lathia JD.

Cell Rep. 2015 May 19;11(7):1031-42. doi: 10.1016/j.celrep.2015.04.021. Epub 2015 May 7.


Development of a Fluorescent Reporter System to Delineate Cancer Stem Cells in Triple-Negative Breast Cancer.

Thiagarajan PS, Hitomi M, Hale JS, Alvarado AG, Otvos B, Sinyuk M, Stoltz K, Wiechert A, Mulkearns-Hubert E, Jarrar A, Zheng Q, Thomas D, Egelhoff T, Rich JN, Liu H, Lathia JD, Reizes O.

Stem Cells. 2015 Jul;33(7):2114-2125. doi: 10.1002/stem.2021. Epub 2015 May 15.


The LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells.

Kim SH, Kim EJ, Hitomi M, Oh SY, Jin X, Jeon HM, Beck S, Jin X, Kim JK, Park CG, Chang SY, Yin J, Kim T, Jeon YJ, Song J, Lim YC, Lathia JD, Nakano I, Kim H.

Cell Death Differ. 2015 Sep;22(9):1517-25. doi: 10.1038/cdd.2015.7. Epub 2015 Feb 27.


Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron.

Visconte V, Avishai N, Mahfouz R, Tabarroki A, Cowen J, Sharghi-Moshtaghin R, Hitomi M, Rogers HJ, Hasrouni E, Phillips J, Sekeres MA, Heuer AH, Saunthararajah Y, Barnard J, Tiu RV.

Leukemia. 2015 Jan;29(1):188-95. doi: 10.1038/leu.2014.170. Epub 2014 May 23.


Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.

Hale JS, Otvos B, Sinyuk M, Alvarado AG, Hitomi M, Stoltz K, Wu Q, Flavahan W, Levison B, Johansen ML, Schmitt D, Neltner JM, Huang P, Ren B, Sloan AE, Silverstein RL, Gladson CL, DiDonato JA, Brown JM, McIntyre T, Hazen SL, Horbinski C, Rich JN, Lathia JD.

Stem Cells. 2014 Jul;32(7):1746-58. doi: 10.1002/stem.1716.


High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor.

Lathia JD, Li M, Sinyuk M, Alvarado AG, Flavahan WA, Stoltz K, Rosager AM, Hale J, Hitomi M, Gallagher J, Wu Q, Martin J, Vidal JG, Nakano I, Dahlrot RH, Hansen S, McLendon RE, Sloan AE, Bao S, Hjelmeland AB, Carson CT, Naik UP, Kristensen B, Rich JN.

Cell Rep. 2014 Jan 16;6(1):117-29. doi: 10.1016/j.celrep.2013.11.043. Epub 2013 Dec 27.


Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.

Lotti F, Jarrar AM, Pai RK, Hitomi M, Lathia J, Mace A, Gantt GA Jr, Sukhdeo K, DeVecchio J, Vasanji A, Leahy P, Hjelmeland AB, Kalady MF, Rich JN.

J Exp Med. 2013 Dec 16;210(13):2851-72. doi: 10.1084/jem.20131195. Epub 2013 Dec 9.


Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake.

Flavahan WA, Wu Q, Hitomi M, Rahim N, Kim Y, Sloan AE, Weil RJ, Nakano I, Sarkaria JN, Stringer BW, Day BW, Li M, Lathia JD, Rich JN, Hjelmeland AB.

Nat Neurosci. 2013 Oct;16(10):1373-82. doi: 10.1038/nn.3510. Epub 2013 Sep 1.


Aptamer identification of brain tumor-initiating cells.

Kim Y, Wu Q, Hamerlik P, Hitomi M, Sloan AE, Barnett GH, Weil RJ, Leahy P, Hjelmeland AB, Rich JN.

Cancer Res. 2013 Aug 1;73(15):4923-36. doi: 10.1158/0008-5472.CAN-12-4556. Epub 2013 Jun 24.


Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells.

Fan Y, Eswarappa SM, Hitomi M, Fox PL.

J Cell Biol. 2012 Jul 9;198(1):47-55. doi: 10.1083/jcb.201111088.


Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity.

Kim Y, Kim E, Wu Q, Guryanova O, Hitomi M, Lathia JD, Serwanski D, Sloan AE, Weil RJ, Lee J, Nishiyama A, Bao S, Hjelmeland AB, Rich JN.

Genes Dev. 2012 Jun 1;26(11):1247-62. doi: 10.1101/gad.193565.112.


Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions.

Lathia JD, Hitomi M, Gallagher J, Gadani SP, Adkins J, Vasanji A, Liu L, Eyler CE, Heddleston JM, Wu Q, Minhas S, Soeda A, Hoeppner DJ, Ravin R, McKay RD, McLendon RE, Corbeil D, Chenn A, Hjelmeland AB, Park DM, Rich JN.

Cell Death Dis. 2011 Sep 1;2:e200. doi: 10.1038/cddis.2011.80.


Glioma stem cell maintenance: the role of the microenvironment.

Heddleston JM, Hitomi M, Venere M, Flavahan WA, Yang K, Kim Y, Minhas S, Rich JN, Hjelmeland AB.

Curr Pharm Des. 2011;17(23):2386-401. Review.


The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons.

Hitomi M, Stacey DW.

Cytometry A. 2010 Jun;77(6):524-33. doi: 10.1002/cyto.a.20885.


Development of high-speed polarizing imaging system for operation in high pulsed magnetic field.

Katakura I, Tokunaga M, Matsuo A, Kawaguchi K, Kindo K, Hitomi M, Akahoshi D, Kuwahara H.

Rev Sci Instrum. 2010 Apr;81(4):043701. doi: 10.1063/1.3359954.


Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression.

Hitomi M, Yang K, Stacey AW, Stacey DW.

Mol Cell Biol. 2008 Sep;28(17):5478-93. doi: 10.1128/MCB.02047-07. Epub 2008 Jul 7.


Cell cycle studies based upon quantitative image analysis.

Stacey DW, Hitomi M.

Cytometry A. 2008 Apr;73(4):270-8. doi: 10.1002/cyto.a.20511. Review.


p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point.

Hitomi M, Yang K, Guo Y, Fretthold J, Harwalkar J, Stacey DW.

Cell Cycle. 2006 Oct;5(19):2281-9. Epub 2006 Oct 1.


Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels.

Yang K, Guo Y, Stacey WC, Harwalkar J, Fretthold J, Hitomi M, Stacey DW.

BMC Cell Biol. 2006 Aug 30;7:33.


Vitamins K2, K3 and K5 exert in vivo antitumor effects on hepatocellular carcinoma by regulating the expression of G1 phase-related cell cycle molecules.

Kuriyama S, Hitomi M, Yoshiji H, Nonomura T, Tsujimoto T, Mitoro A, Akahane T, Ogawa M, Nakai S, Deguchi A, Masaki T, Uchida N.

Int J Oncol. 2005 Aug;27(2):505-11.


In vitro and in vivo antitumor effects of vitamin K5 on hepatocellular carcinoma.

Hitomi M, Nonomura T, Yokoyama F, Yoshiji H, Ogawa M, Nakai S, Deguchi A, Masaki T, Inoue H, Kimura Y, Kurokohchi K, Uchida N, Kuriyama S.

Int J Oncol. 2005 May;26(5):1337-44.


Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis.

Guo Y, Yang K, Harwalkar J, Nye JM, Mason DR, Garrett MD, Hitomi M, Stacey DW.

Oncogene. 2005 Apr 14;24(16):2599-612.


Antitumor effects of vitamins K1, K2 and K3 on hepatocellular carcinoma in vitro and in vivo.

Hitomi M, Yokoyama F, Kita Y, Nonomura T, Masaki T, Yoshiji H, Inoue H, Kinekawa F, Kurokohchi K, Uchida N, Watanabe S, Kuriyama S.

Int J Oncol. 2005 Mar;26(3):713-20.


Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal.

Guo Y, Harwalkar J, Stacey DW, Hitomi M.

Oncogene. 2005 Feb 3;24(6):1032-42.


Proliferative capability of hepatocytes and expression of G1-related cell cycle molecules in the development of liver cirrhosis in rats.

Funakoshi F, Masaki T, Kita Y, Hitomi M, Kurokohchi K, Uchida N, Watanabe S, Yoshiji H, Kuriyama S.

Int J Mol Med. 2004 Jun;13(6):779-87.


The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs.

Watanabe M, Hitomi M, van der Wee K, Rothenberg F, Fisher SA, Zucker R, Svoboda KK, Goldsmith EC, Heiskanen KM, Nieminen AL.

Microsc Microanal. 2002 Oct;8(5):375-91. Review.


Ras is active throughout the cell cycle, but is able to induce cyclin D1 only during G2 phase.

Sa G, Hitomi M, Harwalkar J, Stacey AW, GC GC, Stacey DW.

Cell Cycle. 2002 Jan;1(1):50-8.


Post-transcriptional regulation of cyclin D1 expression during G2 phase.

Guo Y, Stacey DW, Hitomi M.

Oncogene. 2002 Oct 24;21(49):7545-56.


Initiation of apoptosis in the developing avian outflow tract myocardium.

Rothenberg F, Hitomi M, Fisher SA, Watanabe M.

Dev Dyn. 2002 Apr;223(4):469-82.


[Serum leptin levels in normal pregnant women and their babies].

Liu Y, Wang W, Hitomi M.

Zhonghua Fu Chan Ke Za Zhi. 2000 Jul;35(7):392-5. Chinese.


Ras-dependent cell cycle commitment during G2 phase.

Hitomi M, Stacey DW.

FEBS Lett. 2001 Feb 16;490(3):123-31. Review.


Characteristics of Cyclodextrin Adsorption onto Activated Carbons.

Abe I I, Fukuhara T, Kawasaki N, Hitomi M, Kera Y.

J Colloid Interface Sci. 2000 Sep 15;229(2):615-619.


The p38 pathway provides negative feedback for Ras proliferative signaling.

Chen G, Hitomi M, Han J, Stacey DW.

J Biol Chem. 2000 Dec 15;275(50):38973-80.


An unexpected link between the secretory path and the organization of the nucleus.

Nanduri J, Mitra S, Andrei C, Liu Y, Yu Y, Hitomi M, Tartakoff AM.

J Biol Chem. 1999 Nov 19;274(47):33785-9.


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