Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2014 2
2015 2
2016 1
2019 2
2020 2
2021 2
2022 2
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

13 results

Results by year

Filters applied: . Clear all
Page 1
Synthetic antibody-derived immunopeptide provides neuroprotection in glaucoma through molecular interaction with retinal protein histone H3.1.
Fomo KN, Schmelter C, Atta J, Beutgen VM, Schwarz R, Perumal N, Govind G, Speck T, Pfeiffer N, Grus FH. Fomo KN, et al. Front Med (Lausanne). 2022 Oct 14;9:993351. doi: 10.3389/fmed.2022.993351. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36313990 Free PMC article.

Employing state-of the-art immunoprecipitation experiments, we confirmed that synthetic CDR2 exhibited a high affinity toward the retinal target protein histone H3.1 (HIST1H3A) (p < 0.001 and log2-fold change > 3). Furthermore, molecular dynamics (MD) simulations alo

…
Employing state-of the-art immunoprecipitation experiments, we confirmed that synthetic CDR2 exhibited a high affinity toward the retinal ta …
Post-translational Modification Crosstalk and Hotspots in Sirtuin Interactors Implicated in Cardiovascular Diseases.
Aggarwal S, Banerjee SK, Talukdar NC, Yadav AK. Aggarwal S, et al. Front Genet. 2020 Apr 30;11:356. doi: 10.3389/fgene.2020.00356. eCollection 2020. Front Genet. 2020. PMID: 32425973 Free PMC article.
We identified seven proteins (TP53, LMNA, MAPT, ATP2A2, NCL, APEX1, and HIST1H3A) containing disease-associated variants in PTM and crosstalk hotspots. ...
We identified seven proteins (TP53, LMNA, MAPT, ATP2A2, NCL, APEX1, and HIST1H3A) containing disease-associated variants in PTM and c …
Identification of a RNA-seq-based signature to improve prognostics for uterine sarcoma.
Zhou JG, Zhao HT, Jin SH, Tian X, Ma H. Zhou JG, et al. Gynecol Oncol. 2019 Dec;155(3):499-507. doi: 10.1016/j.ygyno.2019.08.033. Epub 2019 Oct 26. Gynecol Oncol. 2019. PMID: 31662204
RESULTS: This study identified a prognostic signature based on 6 genes: FGF23, TLX2, TIFAB, RNF223, HIST1H3A and AADACL4. In the training group, the median OS in the high- and low-risk groups was 19.6 vs 88.1 months (HR, 0.1412, 95% CI: 0.03295 - 0.6054; P = 0.002), respec …
RESULTS: This study identified a prognostic signature based on 6 genes: FGF23, TLX2, TIFAB, RNF223, HIST1H3A and AADACL4. In the trai …
Spatial and Temporal Expression of High-Mobility-Group Nucleosome-Binding (HMGN) Genes in Brain Areas Associated with Cognition in Individuals with Down Syndrome.
Rodríguez-Ortiz A, Montoya-Villegas JC, García-Vallejo F, Mina-Paz Y. Rodríguez-Ortiz A, et al. Genes (Basel). 2021 Dec 17;12(12):2000. doi: 10.3390/genes12122000. Genes (Basel). 2021. PMID: 34946949 Free PMC article.
From the BioGRID database, we registered high interaction scores of HMGN2 and HMGN4 with Hist1H1A and Hist1H3A. Conclusions: Overall, our results give strong evidence to propose that DS would be an epigenetics-based aneuploidy. ...
From the BioGRID database, we registered high interaction scores of HMGN2 and HMGN4 with Hist1H1A and Hist1H3A. Conclusions: Overall, …
Transcriptome analysis of the human corneal endothelium.
Frausto RF, Wang C, Aldave AJ. Frausto RF, et al. Invest Ophthalmol Vis Sci. 2014 Nov 6;55(12):7821-30. doi: 10.1167/iovs.14-15021. Invest Ophthalmol Vis Sci. 2014. PMID: 25377225 Free PMC article.
Nine genes displayed the most significant differential expression between pediatric and adult HCEnC: CAPN6, HIST1H3A, HIST1H4E, and HSPA2 were expressed at higher levels in pediatric HCEnC, while ITGBL1, NALCN, PREX2, TAC1, and TMOD1 were expressed at higher levels in adul …
Nine genes displayed the most significant differential expression between pediatric and adult HCEnC: CAPN6, HIST1H3A, HIST1H4E, and H …
Differential gene co-expression network analyses reveal novel molecules associated with transcriptional dysregulation of key biological processes in osteoarthritis knee cartilage.
Buzzatto-Leite I, Afonso J, Silva-Vignato B, Coutinho LL, Alvares LE. Buzzatto-Leite I, et al. Osteoarthr Cartil Open. 2022 Oct 23;4(4):100316. doi: 10.1016/j.ocarto.2022.100316. eCollection 2022 Dec. Osteoarthr Cartil Open. 2022. PMID: 36474801 Free PMC article.
The top hub and hub centrality genes of these networks were HIST1H3A and SNHG12 (normal) and TAF9B and OTUD1 (osteoarthritis). ...
The top hub and hub centrality genes of these networks were HIST1H3A and SNHG12 (normal) and TAF9B and OTUD1 (osteoarthritis). ...
Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Zao-Jiao-Ci in the Treatment of LSCC.
Xiang F, Li L, Lin J, Li S, Peng G. Xiang F, et al. J Oncol. 2021 Jun 25;2021:8862821. doi: 10.1155/2021/8862821. eCollection 2021. J Oncol. 2021. PMID: 34257654 Free PMC article.
We found that LSCC patients with high expression of HIST1H3J, HIST1H3F, and ITGA4 had worse overall survival, while higher expression of NTRK1, COPS5, HIST1H3A, and HIST1H3G had significantly worse disease-free survival. ...
We found that LSCC patients with high expression of HIST1H3J, HIST1H3F, and ITGA4 had worse overall survival, while higher expression of NTR …
Expression patterns of immune-associated genes in external genital and perianal warts treated with sinecatechins.
Doan HQ, Nguyen HP, Rady P, Tyring SK. Doan HQ, et al. Viral Immunol. 2015 May;28(4):236-40. doi: 10.1089/vim.2014.0144. Epub 2015 Mar 16. Viral Immunol. 2015. PMID: 25774455
Genes that were significantly regulated between VRs and VNRs were CREB3L4, HIST1H3A, HIST1H3H, IFNA1, IFNA4, IFNA5, IFNA6, IFNA8, IFNA14, IFNG, IFNAR1, IL6, IRF9, MAPK4, MAPK5, MAPK14, NET1, and PIK3C2A in the IFN array. ...
Genes that were significantly regulated between VRs and VNRs were CREB3L4, HIST1H3A, HIST1H3H, IFNA1, IFNA4, IFNA5, IFNA6, IFNA8, IFN …
Novel sensor-integrated proteome on chip (SPOC) platform with thousands of folded proteins on a 1.5 sq-cm biosensor chip to enable high-throughput real-time label-free screening for kinetic analysis.
Agu CV, Cook RL, Martelly W, Gushgari LR, Mohan M, Takulapalli B. Agu CV, et al. bioRxiv [Preprint]. 2024 Jan 24:2024.01.23.575909. doi: 10.1101/2024.01.23.575909. bioRxiv. 2024. PMID: 38328216 Free PMC article. Preprint.
The functionality of the SPOC protein array was validated by antibody binding assay, post-translational modification, mutation-mediated differential binding kinetics, and catalytic activity screening on model SPOC protein arrays containing p53, Src, Jun, Fos, HIST1H3A, and …
The functionality of the SPOC protein array was validated by antibody binding assay, post-translational modification, mutation-mediated diff …
DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas.
Schramm K, Iskar M, Statz B, Jäger N, Haag D, Słabicki M, Pfister SM, Zapatka M, Gronych J, Jones DTW, Lichter P. Schramm K, et al. Neuro Oncol. 2019 Jul 11;21(7):867-877. doi: 10.1093/neuonc/noz057. Neuro Oncol. 2019. PMID: 30943283 Free PMC article.
BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive pediatric brain tumors that are characterized by a recurrent mutation (K27M) within the histone H3 encoding genes H3F3A and HIST1H3A/B/C. These mutations have been shown to induce a global reductio …
BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive pediatric brain tumors that are characterized by a recurrent mut …
13 results