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Items: 10

1.

Physiologically based pharmacokinetic modeling of cyclohexane as a tool for integrating animal and human test data.

Hissink AM, Kulig BM, Kruse J, Freidig AP, Verwei M, Muijser H, Lammers JH, McKee RH, Owen DE, Sweeney LM, Salmon F.

Int J Toxicol. 2009 Nov-Dec;28(6):498-509. doi: 10.1177/1091581809348718.

PMID:
19966142
2.

Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents III. PBPK modeling of white spirit constituents as a tool for integrating animal and human test data.

Hissink AM, Krüse J, Kulig BM, Verwei M, Muijser H, Salmon F, Leenheers LH, Owen DE, Lammers JH, Freidig AP, McKee RH.

Neurotoxicology. 2007 Jul;28(4):751-60. Epub 2007 Mar 24.

PMID:
17493682
3.

A physiologically-based pharmacokinetic(PB-PK) model for ethylene dibromide: relevance of extrahepatic metabolism.

Hissink AM, Wormhoudt LW, Sherratt PJ, Hayes JD, Commandeur JN, Vermeulen NP, van Bladeren PJ.

Food Chem Toxicol. 2000 Aug;38(8):707-16.

PMID:
10908818
4.

Disposition of 1,2-[14C]Dibromoethane in male Wistar rats.

Wormhoudt LW, Hissink AM, Commandeur JN, van Bladeren PJ, Vermeulen NP.

Drug Metab Dispos. 1998 May;26(5):437-47.

PMID:
9571225
5.

A physiologically based pharmacokinetic (PB-PK) model for 1,2-dichlorobenzene linked to two possible parameters of toxicity.

Hissink AM, Van Ommen B, Krüse J, Van Bladeren PJ.

Toxicol Appl Pharmacol. 1997 Aug;145(2):301-10.

PMID:
9266803
6.

Species and strain differences in the hepatic cytochrome P450-mediated biotransformation of 1,4-dichlorobenzene.

Hissink AM, Oudshoorn MJ, Van Ommen B, Van Bladeren PJ.

Toxicol Appl Pharmacol. 1997 Jul;145(1):1-9.

PMID:
9221818
7.

Kinetics and metabolism of 1,4-dichlorobenzene in male Wistar rats: no evidence for quinone metabolites.

Hissink AM, Dunnewijk R, van Ommen B, van Bladeren PJ.

Chem Biol Interact. 1997 Jan 24;103(1):17-33.

PMID:
9051121
8.

Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.

Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.

Chem Res Toxicol. 1996 Dec;9(8):1249-56.

PMID:
8951226
9.

Dose-dependent kinetics and metabolism of 1,2-dichlorobenzene in rat: effect of pretreatment with phenobarbital.

Hissink AM, Van Ommen B, Van Bladeren PJ.

Xenobiotica. 1996 Jan;26(1):89-105.

PMID:
8851824
10.

Several known indole compounds are not important precursors of direct mutagenic N-nitroso compounds in green cabbage.

Tiedink HG, Hissink AM, Lodema SM, van Broekhoven LW, Jongen WM.

Mutat Res. 1990 Oct;232(2):199-207.

PMID:
2215529

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