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Items: 41


Empowering Women: Moving from Awareness to Action at the Immunology of Fungal Infections Gordon Research Conference.

Ballou ER, Gaffen SL, Gow NAR, Hise AG.

Pathogens. 2019 Jul 17;8(3). pii: E103. doi: 10.3390/pathogens8030103.


Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Aspergillus fumigatus Infection.

Sun Y, Abbondante S, Karmakar M, de Jesus Carrion S, Che C, Hise AG, Pearlman E.

J Immunol. 2018 Nov 1;201(9):2767-2775. doi: 10.4049/jimmunol.1701195. Epub 2018 Sep 28.


IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.

Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL.

Cell Host Microbe. 2016 Nov 9;20(5):606-617. doi: 10.1016/j.chom.2016.10.001. Epub 2016 Oct 27.


T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.

Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, Pavicic PG Jr, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X.

Nat Immunol. 2016 May;17(5):583-92. doi: 10.1038/ni.3389. Epub 2016 Mar 21.


Inflammasomes in aspergillosis--it takes two to tango.

Tomalka J, Hise AG.

Cell Host Microbe. 2015 Mar 11;17(3):290-292. doi: 10.1016/j.chom.2015.02.017.


Factors associated with severe human Rift Valley fever in Sangailu, Garissa County, Kenya.

LaBeaud AD, Pfeil S, Muiruri S, Dahir S, Sutherland LJ, Traylor Z, Gildengorin G, Muchiri EM, Morrill J, Peters CJ, Hise AG, Kazura JW, King CH.

PLoS Negl Trop Dis. 2015 Mar 12;9(3):e0003548. doi: 10.1371/journal.pntd.0003548. eCollection 2015 Mar.


Association of symptoms and severity of rift valley fever with genetic polymorphisms in human innate immune pathways.

Hise AG, Traylor Z, Hall NB, Sutherland LJ, Dahir S, Ermler ME, Muiruri S, Muchiri EM, Kazura JW, LaBeaud AD, King CH, Stein CM.

PLoS Negl Trop Dis. 2015 Mar 10;9(3):e0003584. doi: 10.1371/journal.pntd.0003584. eCollection 2015 Mar.


Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E.

J Immunol. 2015 Feb 15;194(4):1763-75. doi: 10.4049/jimmunol.1401624. Epub 2015 Jan 21.


β-Defensin 1 plays a role in acute mucosal defense against Candida albicans.

Tomalka J, Azodi E, Narra HP, Patel K, O'Neill S, Cardwell C, Hall BA, Wilson JM, Hise AG.

J Immunol. 2015 Feb 15;194(4):1788-95. doi: 10.4049/jimmunol.1203239. Epub 2015 Jan 16.


A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.

Nilsen NJ, Vladimer GI, Stenvik J, Orning MP, Zeid-Kilani MV, Bugge M, Bergstroem B, Conlon J, Husebye H, Hise AG, Fitzgerald KA, Espevik T, Lien E.

J Biol Chem. 2015 Feb 6;290(6):3209-22. doi: 10.1074/jbc.M114.593426. Epub 2014 Dec 11.


Innate Defense against Fungal Pathogens.

Drummond RA, Gaffen SL, Hise AG, Brown GD.

Cold Spring Harb Perspect Med. 2014 Nov 10;5(6). pii: a019620. doi: 10.1101/cshperspect.a019620. Review.


Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VAK, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-2530. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.


MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.

Yu M, Zhou H, Zhao J, Xiao N, Roychowdhury S, Schmitt D, Hu B, Ransohoff RM, Harding CV, Hise AG, Hazen SL, DeFranco AL, Fox PL, Morton RE, Dicorleto PE, Febbraio M, Nagy LE, Smith JD, Wang JA, Li X.

J Exp Med. 2014 May 5;211(5):887-907. doi: 10.1084/jem.20131314. Epub 2014 Apr 21. Erratum in: J Exp Med. 2014 May 5;211(5):1003. Ransohoff, Richard M [added].


Activity of potent and selective host defense peptide mimetics in mouse models of oral candidiasis.

Ryan LK, Freeman KB, Masso-Silva JA, Falkovsky K, Aloyouny A, Markowitz K, Hise AG, Fatahzadeh M, Scott RW, Diamond G.

Antimicrob Agents Chemother. 2014 Jul;58(7):3820-7. doi: 10.1128/AAC.02649-13. Epub 2014 Apr 21.


Alcohol-induced liver injury is modulated by Nlrp3 and Nlrc4 inflammasomes in mice.

DeSantis DA, Ko CW, Liu Y, Liu X, Hise AG, Nunez G, Croniger CM.

Mediators Inflamm. 2013;2013:751374. doi: 10.1155/2013/751374. Epub 2013 Dec 16.


Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.

Ermler ME, Traylor Z, Patel K, Schattgen SA, Vanaja SK, Fitzgerald KA, Hise AG.

Virology. 2014 Jan 20;449:174-80. doi: 10.1016/j.virol.2013.11.015. Epub 2013 Dec 3.


Reduced frequency of a CD14+ CD16+ monocyte subset with high Toll-like receptor 4 expression in cord blood compared to adult blood contributes to lipopolysaccharide hyporesponsiveness in newborns.

Pedraza-Sánchez S, Hise AG, Ramachandra L, Arechavaleta-Velasco F, King CL.

Clin Vaccine Immunol. 2013 Jul;20(7):962-71. doi: 10.1128/CVI.00609-12. Epub 2013 Apr 17.


RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge.

Ermler ME, Yerukhim E, Schriewer J, Schattgen S, Traylor Z, Wespiser AR, Caffrey DR, Chen ZJ, King CH, Gale M Jr, Colonna M, Fitzgerald KA, Buller RM, Hise AG.

J Virol. 2013 May;87(9):4846-60. doi: 10.1128/JVI.01997-12. Epub 2013 Feb 13.


Host defense at the ocular surface.

Pearlman E, Sun Y, Roy S, Karmakar M, Hise AG, Szczotka-Flynn L, Ghannoum M, Chinnery HR, McMenamin PG, Rietsch A.

Int Rev Immunol. 2013 Feb;32(1):4-18. doi: 10.3109/08830185.2012.749400. Review.


Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1.

Karmakar M, Sun Y, Hise AG, Rietsch A, Pearlman E.

J Immunol. 2012 Nov 1;189(9):4231-5. doi: 10.4049/jimmunol.1201447. Epub 2012 Sep 28.


Ocular manifestations of the autoinflammatory syndromes.

Tarabishy AB, Hise AG, Traboulsi EI.

Ophthalmic Genet. 2012 Dec;33(4):179-86. doi: 10.3109/13816810.2012.695421. Epub 2012 Aug 27. Review.


A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.

Tomalka J, Ganesan S, Azodi E, Patel K, Majmudar P, Hall BA, Fitzgerald KA, Hise AG.

PLoS Pathog. 2011 Dec;7(12):e1002379. doi: 10.1371/journal.ppat.1002379. Epub 2011 Dec 8.


Arbovirus prevalence in mosquitoes, Kenya.

LaBeaud AD, Sutherland LJ, Muiruri S, Muchiri EM, Gray LR, Zimmerman PA, Hise AG, King CH.

Emerg Infect Dis. 2011 Feb;17(2):233-41. doi: 10.3201/eid1702.091666.


Bacterial pathogen-associated molecular patterns stimulate biological activity of orthopaedic wear particles by activating cognate Toll-like receptors.

Greenfield EM, Beidelschies MA, Tatro JM, Goldberg VM, Hise AG.

J Biol Chem. 2010 Oct 15;285(42):32378-84. doi: 10.1074/jbc.M110.136895. Epub 2010 Aug 19.


CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.

Reed-Geaghan EG, Savage JC, Hise AG, Landreth GE.

J Neurosci. 2009 Sep 23;29(38):11982-92. doi: 10.1523/JNEUROSCI.3158-09.2009.


An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.

Hise AG, Tomalka J, Ganesan S, Patel K, Hall BA, Brown GD, Fitzgerald KA.

Cell Host Microbe. 2009 May 8;5(5):487-97. doi: 10.1016/j.chom.2009.05.002.


TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

Drage MG, Pecora ND, Hise AG, Febbraio M, Silverstein RL, Golenbock DT, Boom WH, Harding CV.

Cell Immunol. 2009;258(1):29-37. doi: 10.1016/j.cellimm.2009.03.008. Epub 2009 Apr 11.


An early complement-dependent and TLR-4-independent phase in the pathogenesis of ethanol-induced liver injury in mice.

Roychowdhury S, McMullen MR, Pritchard MT, Hise AG, van Rooijen N, Medof ME, Stavitsky AB, Nagy LE.

Hepatology. 2009 Apr;49(4):1326-34. doi: 10.1002/hep.22776.


Toll-like receptor 2 regulates CXC chemokine production and neutrophil recruitment to the cornea in Onchocerca volvulus/Wolbachia-induced keratitis.

Gillette-Ferguson I, Daehnel K, Hise AG, Sun Y, Carlson E, Diaconu E, McGarry HF, Taylor MJ, Pearlman E.

Infect Immun. 2007 Dec;75(12):5908-15. Epub 2007 Sep 17.


Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E.

J Immunol. 2007 Jan 15;178(2):1068-76.


Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88.

Gillette-Ferguson I, Hise AG, Sun Y, Diaconu E, McGarry HF, Taylor MJ, Pearlman E.

Infect Immun. 2006 Apr;74(4):2442-5.


Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.

Johnson AC, Heinzel FP, Diaconu E, Sun Y, Hise AG, Golenbock D, Lass JH, Pearlman E.

Invest Ophthalmol Vis Sci. 2005 Feb;46(2):589-95.


Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness).

Gillette-Ferguson I, Hise AG, McGarry HF, Turner J, Esposito A, Sun Y, Diaconu E, Taylor MJ, Pearlman E.

Infect Immun. 2004 Oct;72(10):5687-92.


The role of endosymbiotic Wolbachia bacteria in filarial disease.

Hise AG, Gillette-Ferguson I, Pearlman E.

Cell Microbiol. 2004 Feb;6(2):97-104. Review.


Polymorphisms of innate immunity genes and susceptibility to lymphatic filariasis.

Hise AG, Hazlett FE, Bockarie MJ, Zimmerman PA, Tisch DJ, Kazura JW.

Genes Immun. 2003 Oct;4(7):524-7.


Bactericidal activity in whole blood as a potential surrogate marker of immunity after vaccination against tuberculosis.

Cheon SH, Kampmann B, Hise AG, Phillips M, Song HY, Landen K, Li Q, Larkin R, Ellner JJ, Silver RF, Hoft DF, Wallis RS.

Clin Diagn Lab Immunol. 2002 Jul;9(4):901-7.


The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness.

Saint André Av, Blackwell NM, Hall LR, Hoerauf A, Brattig NW, Volkmann L, Taylor MJ, Ford L, Hise AG, Lass JH, Diaconu E, Pearlman E.

Science. 2002 Mar 8;295(5561):1892-5.


A whole blood bactericidal assay for tuberculosis.

Wallis RS, Palaci M, Vinhas S, Hise AG, Ribeiro FC, Landen K, Cheon SH, Song HY, Phillips M, Dietze R, Ellner JJ.

J Infect Dis. 2001 Apr 15;183(8):1300-3. Epub 2001 Mar 8.


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