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Genetics. 2012 Mar;190(3):1145-8. doi: 10.1534/genetics.111.136697. Epub 2011 Dec 29.

Extended linkage disequilibrium in noncoding regions in a conifer, Cryptomeria japonica.

Author information

1
Department of Biology, Kyushu University, Fukuoka 812-8581, Japan.

Abstract

We measured linkage disequilibrium in mostly noncoding regions of Cryptomeria japonica, a conifer belonging to Cupressaceae. Linkage disequilibrium was extensive and did not decay even at a distance of 100 kb. The average estimate of the population recombination rate per base pair was 1.55 × 10(-5) and was <1/70 of that in the coding regions. We discuss the impact of low recombination rates in a large part of the genome on association studies.

PMID:
22209904
PMCID:
PMC3296249
DOI:
10.1534/genetics.111.136697
[Indexed for MEDLINE]
Free PMC Article

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