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Items: 1 to 50 of 522

1.

Magia: Robust Automated Image Processing and Kinetic Modeling Toolbox for PET Neuroinformatics.

Karjalainen T, Tuisku J, Santavirta S, Kantonen T, Bucci M, Tuominen L, Hirvonen J, Hietala J, Rinne JO, Nummenmaa L.

Front Neuroinform. 2020 Feb 4;14:3. doi: 10.3389/fninf.2020.00003. eCollection 2020.

2.

Implementation of a 23-h surgery model in a tertiary care hospital: a safe and feasible model with high patient satisfaction.

Ruohoaho UM, Toroi P, Hirvonen J, Aaltomaa S, Kokki H, Kokki M.

BJS Open. 2020 Feb 28. doi: 10.1002/bjs5.50267. [Epub ahead of print]

3.

Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study.

Rebelos E, Hirvonen J, Bucci M, Pekkarinen L, Nyman M, Hannukainen JC, Iozzo P, Salminen P, Nummenmaa L, Ferrannini E, Nuutila P.

Diabetes Obes Metab. 2020 Feb 12. doi: 10.1111/dom.13996. [Epub ahead of print]

PMID:
32052537
4.

The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties.

Shahbazi MA, Faghfouri L, Ferreira MPA, Figueiredo P, Maleki H, Sefat F, Hirvonen J, Santos HA.

Chem Soc Rev. 2020 Feb 21;49(4):1253-1321. doi: 10.1039/c9cs00283a. Epub 2020 Jan 30. Review.

PMID:
31998912
5.

Fabrication and Characterization of Drug-Loaded Conductive Poly(glycerol sebacate)/Nanoparticle-Based Composite Patch for Myocardial Infarction Applications.

Zanjanizadeh Ezazi N, Ajdary R, Correia A, Mäkilä E, Salonen J, Kemell M, Hirvonen J, Rojas OJ, Ruskoaho HJ, Santos HA.

ACS Appl Mater Interfaces. 2020 Feb 12;12(6):6899-6909. doi: 10.1021/acsami.9b21066. Epub 2020 Feb 3.

PMID:
31967771
6.

Dual-peptide functionalized acetalated dextran-based nanoparticles for sequential targeting of macrophages during myocardial infarction.

Torrieri G, Fontana F, Figueiredo P, Liu Z, Ferreira MPA, Talman V, Martins JP, Fusciello M, Moslova K, Teesalu T, Cerullo V, Hirvonen J, Ruskoaho H, Balasubramanian V, Santos HA.

Nanoscale. 2020 Jan 28;12(4):2350-2358. doi: 10.1039/c9nr09934d. Epub 2020 Jan 13.

PMID:
31930241
7.

Dissociable neural systems for unconditioned acute and sustained fear.

Hudson M, Seppälä K, Putkinen V, Sun L, Glerean E, Karjalainen T, Karlsson HK, Hirvonen J, Nummenmaa L.

Neuroimage. 2020 Jan 8:116522. doi: 10.1016/j.neuroimage.2020.116522. [Epub ahead of print]

8.

Artificially cloaked viral nanovaccine for cancer immunotherapy.

Fusciello M, Fontana F, Tähtinen S, Capasso C, Feola S, Martins B, Chiaro J, Peltonen K, Ylösmäki L, Ylösmäki E, Hamdan F, Kari OK, Ndika J, Alenius H, Urtti A, Hirvonen JT, Santos HA, Cerullo V.

Nat Commun. 2019 Dec 17;10(1):5747. doi: 10.1038/s41467-019-13744-8.

9.

Microfluidics for Production of Particles: Mechanism, Methodology, and Applications.

Liu Z, Fontana F, Python A, Hirvonen JT, Santos HA.

Small. 2020 Mar;16(9):e1904673. doi: 10.1002/smll.201904673. Epub 2019 Nov 8. Review.

PMID:
31702878
10.

Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke.

Balasubramanian V, Domanskyi A, Renko JM, Sarparanta M, Wang CF, Correia A, Mäkilä E, Alanen OS, Salonen J, Airaksinen AJ, Tuominen R, Hirvonen J, Airavaara M, Santos HA.

Biomaterials. 2020 Jan;227:119556. doi: 10.1016/j.biomaterials.2019.119556. Epub 2019 Oct 18.

11.

Effect of Phytase on in Vitro Hydrolysis of Phytate and the Formation of myo-Inositol Phosphate Esters in Various Feed Materials.

Hirvonen J, Liljavirta J, Saarinen MT, Lehtinen MJ, Ahonen I, Nurminen P.

J Agric Food Chem. 2019 Oct 16;67(41):11396-11402. doi: 10.1021/acs.jafc.9b03919. Epub 2019 Oct 3.

PMID:
31537068
12.

The effect of 2'-fucosyllactose on simulated infant gut microbiome and metabolites; a pilot study in comparison to GOS and lactose.

Salli K, Anglenius H, Hirvonen J, Hibberd AA, Ahonen I, Saarinen MT, Tiihonen K, Maukonen J, Ouwehand AC.

Sci Rep. 2019 Sep 13;9(1):13232. doi: 10.1038/s41598-019-49497-z.

13.

Correction to "Targeted Reinforcement of Macrophage Reprogramming Toward M2 Polarization by IL-4-Loaded Hyaluronic Acid Particles".

Shahbazi MA, Sedighi M, Bauleth-Ramos T, Kant K, Correia A, Poursina N, Sarmento B, Hirvonen J, Santos HA.

ACS Omega. 2019 Mar 28;4(3):5931. doi: 10.1021/acsomega.9b00668. eCollection 2019 Mar 31.

14.

Targeted Reinforcement of Macrophage Reprogramming Toward M2 Polarization by IL-4-Loaded Hyaluronic Acid Particles.

Shahbazi MA, Sedighi M, Bauleth-Ramos T, Kant K, Correia A, Poursina N, Sarmento B, Hirvonen J, Santos HA.

ACS Omega. 2018 Dec 27;3(12):18444-18455. doi: 10.1021/acsomega.8b03182. eCollection 2018 Dec 31. Erratum in: ACS Omega. 2019 Mar 28;4(3):5931.

15.

Prevalence of thoracic aortic aneurysms and dilatations in patients with intracranial aneurysms.

Laukka D, Pan E, Fordell T, Alpay K, Rahi M, Hirvonen J, Rinne J, Gunn J.

J Vasc Surg. 2019 Dec;70(6):1801-1808. doi: 10.1016/j.jvs.2019.01.066. Epub 2019 Jul 18.

PMID:
31327605
16.

Novel Genes and Metabolite Trends in Bifidobacterium longum subsp. infantis Bi-26 Metabolism of Human Milk Oligosaccharide 2'-fucosyllactose.

Zabel B, Yde CC, Roos P, Marcussen J, Jensen HM, Salli K, Hirvonen J, Ouwehand AC, Morovic W.

Sci Rep. 2019 May 28;9(1):7983. doi: 10.1038/s41598-019-43780-9.

17.

Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor.

Fontana F, Fusciello M, Groeneveldt C, Capasso C, Chiaro J, Feola S, Liu Z, Mäkilä EM, Salonen JJ, Hirvonen JT, Cerullo V, Santos HA.

ACS Nano. 2019 Jun 25;13(6):6477-6490. doi: 10.1021/acsnano.8b09613. Epub 2019 May 17.

18.

Preparation and Characterization of Dentin Phosphophoryn-Derived Peptide-Functionalized Lignin Nanoparticles for Enhanced Cellular Uptake.

Figueiredo P, Sipponen MH, Lintinen K, Correia A, Kiriazis A, Yli-Kauhaluoma J, Österberg M, George A, Hirvonen J, Kostiainen MA, Santos HA.

Small. 2019 Jun;15(24):e1901427. doi: 10.1002/smll.201901427. Epub 2019 May 6.

PMID:
31062448
19.

Automatic real-time uncertainty estimation for online measurements: a case study on water turbidity.

Kahiluoto J, Hirvonen J, Näykki T.

Environ Monit Assess. 2019 Apr 2;191(5):259. doi: 10.1007/s10661-019-7374-7.

20.

Evaluation of two tuberculosis PCR assays for routine use in a clinical setting of low population and low tuberculosis prevalence.

Luukinen BV, Vuento R, Hirvonen JJ.

APMIS. 2019 Jun;127(6):462-467. doi: 10.1111/apm.12947. Epub 2019 Apr 11.

PMID:
30901113
21.

Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects.

Johansson J, Hirvonen J, Lovró Z, Ekblad L, Kaasinen V, Rajasilta O, Helin S, Tuisku J, Sirén S, Pennanen M, Agrawal A, Crystal R, Vainio PJ, Alho H, Scheinin M.

Neuropsychopharmacology. 2019 Aug;44(9):1667-1673. doi: 10.1038/s41386-019-0368-x. Epub 2019 Mar 13.

PMID:
30867551
22.

Pharmacy Practice and Education in Finland.

Hirvonen J, Salminen O, Vuorensola K, Katajavuori N, Huhtala H, Atkinson J.

Pharmacy (Basel). 2019 Feb 23;7(1). pii: E21. doi: 10.3390/pharmacy7010021.

23.

Microfluidic Nanoassembly of Bioengineered Chitosan-Modified FcRn-Targeted Porous Silicon Nanoparticles @ Hypromellose Acetate Succinate for Oral Delivery of Antidiabetic Peptides.

Martins JP, Liu D, Fontana F, Ferreira MPA, Correia A, Valentino S, Kemell M, Moslova K, Mäkilä E, Salonen J, Hirvonen J, Sarmento B, Santos HA.

ACS Appl Mater Interfaces. 2018 Dec 26;10(51):44354-44367. doi: 10.1021/acsami.8b20821. Epub 2018 Dec 17.

PMID:
30525379
24.

Comparison of three multiplex real-time PCR assays for detection of enteric viruses in patients with diarrhea.

Hirvonen JJ.

Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):241-244. doi: 10.1007/s10096-018-3418-0. Epub 2018 Nov 9.

PMID:
30414091
25.

Dynamic large-scale network synchronization from perception to action.

Hirvonen J, Monto S, Wang SH, Palva JM, Palva S.

Netw Neurosci. 2018 Oct 1;2(4):442-463. doi: 10.1162/netn_a_00039. eCollection 2018.

26.

Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine.

Li W, Li Y, Liu Z, Kerdsakundee N, Zhang M, Zhang F, Liu X, Bauleth-Ramos T, Lian W, Mäkilä E, Kemell M, Ding Y, Sarmento B, Wiwattanapatapee R, Salonen J, Zhang H, Hirvonen JT, Liu D, Deng X, Santos HA.

Biomaterials. 2018 Dec;185:322-332. doi: 10.1016/j.biomaterials.2018.09.024. Epub 2018 Sep 19.

27.

High-Generation Amphiphilic Janus-Dendrimers as Stabilizing Agents for Drug Suspensions.

Selin M, Nummelin S, Deleu J, Ropponen J, Viitala T, Lahtinen M, Koivisto J, Hirvonen J, Peltonen L, Kostiainen MA, Bimbo LM.

Biomacromolecules. 2018 Oct 8;19(10):3983-3993. doi: 10.1021/acs.biomac.8b00931. Epub 2018 Sep 12.

PMID:
30207704
28.

Brain neurokinin-1 receptor availability in never-medicated patients with major depression - A pilot study.

Nyman M, Eskola O, Kajander J, Jokinen R, Penttinen J, Karjalainen T, Nummenmaa L, Hirvonen J, Burns D, Hargreaves R, Solin O, Hietala J.

J Affect Disord. 2019 Jan 1;242:188-194. doi: 10.1016/j.jad.2018.08.084. Epub 2018 Aug 25.

PMID:
30193189
29.

Impact of Pore Size and Surface Chemistry of Porous Silicon Particles and Structure of Phospholipids on Their Interactions.

Liu D, Lipponen K, Quan P, Wan X, Zhang H, Mäkilä E, Salonen J, Kostiainen R, Hirvonen J, Kotiaho T, Santos HA.

ACS Biomater Sci Eng. 2018 Jul 9;4(7):2308-2313. doi: 10.1021/acsbiomaterials.8b00343. Epub 2018 Jun 14.

30.

Decreased Cannabinoid CB1 Receptors in Male Tobacco Smokers Examined With Positron Emission Tomography.

Hirvonen J, Zanotti-Fregonara P, Gorelick DA, Lyoo CH, Rallis-Frutos D, Morse C, Zoghbi SS, Pike VW, Volkow ND, Huestis MA, Innis RB.

Biol Psychiatry. 2018 Nov 15;84(10):715-721. doi: 10.1016/j.biopsych.2018.07.009. Epub 2018 Jul 21.

31.

Aerobic exercise modulates anticipatory reward processing via the μ-opioid receptor system.

Saanijoki T, Nummenmaa L, Tuulari JJ, Tuominen L, Arponen E, Kalliokoski KK, Hirvonen J.

Hum Brain Mapp. 2018 Oct;39(10):3972-3983. doi: 10.1002/hbm.24224. Epub 2018 Jun 8.

PMID:
29885086
32.

Engineered Multifunctional Albumin-Decorated Porous Silicon Nanoparticles for FcRn Translocation of Insulin.

Martins JP, D'Auria R, Liu D, Fontana F, Ferreira MPA, Correia A, Kemell M, Moslova K, Mäkilä E, Salonen J, Casettari L, Hirvonen J, Sarmento B, Santos HA.

Small. 2018 Jul;14(27):e1800462. doi: 10.1002/smll.201800462. Epub 2018 May 31.

PMID:
29855134
33.

Production of pure drug nanocrystals and nano co-crystals by confinement methods.

Fontana F, Figueiredo P, Zhang P, Hirvonen JT, Liu D, Santos HA.

Adv Drug Deliv Rev. 2018 Jun;131:3-21. doi: 10.1016/j.addr.2018.05.002. Epub 2018 May 5. Review.

PMID:
29738786
34.

μ-opioid receptor system mediates reward processing in humans.

Nummenmaa L, Saanijoki T, Tuominen L, Hirvonen J, Tuulari JJ, Nuutila P, Kalliokoski K.

Nat Commun. 2018 Apr 16;9(1):1500. doi: 10.1038/s41467-018-03848-y.

35.

Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue.

Lahesmaa M, Eriksson O, Gnad T, Oikonen V, Bucci M, Hirvonen J, Koskensalo K, Teuho J, Niemi T, Taittonen M, Lahdenpohja S, U Din M, Haaparanta-Solin M, Pfeifer A, Virtanen KA, Nuutila P.

Diabetes. 2018 Jul;67(7):1226-1236. doi: 10.2337/db17-1366. Epub 2018 Apr 12.

36.

Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4-NKX2-5 Interaction.

Kinnunen SM, Tölli M, Välimäki MJ, Gao E, Szabo Z, Rysä J, Ferreira MPA, Ohukainen P, Serpi R, Correia A, Mäkilä E, Salonen J, Hirvonen J, Santos HA, Ruskoaho H.

Sci Rep. 2018 Mar 15;8(1):4611. doi: 10.1038/s41598-018-22830-8.

37.

Tailoring Porous Silicon for Biomedical Applications: From Drug Delivery to Cancer Immunotherapy.

Li W, Liu Z, Fontana F, Ding Y, Liu D, Hirvonen JT, Santos HA.

Adv Mater. 2018 Jun;30(24):e1703740. doi: 10.1002/adma.201703740. Epub 2018 Mar 13. Review.

PMID:
29534311
38.

Simultaneous PET-MRI Confirms That Cerebral Blood Flow Does Not Confound PET Neuroreceptor Activation Studies.

Nummenmaa L, Tuominen L, Hirvonen J.

ACS Chem Neurosci. 2018 Feb 21;9(2):159-161. doi: 10.1021/acschemneuro.7b00489. Epub 2018 Jan 5.

PMID:
29303246
39.

Drug nanocrystals - Versatile option for formulation of poorly soluble materials.

Peltonen L, Hirvonen J.

Int J Pharm. 2018 Feb 15;537(1-2):73-83. doi: 10.1016/j.ijpharm.2017.12.005. Epub 2017 Dec 17.

PMID:
29262301
40.

Conductive vancomycin-loaded mesoporous silica polypyrrole-based scaffolds for bone regeneration.

Zanjanizadeh Ezazi N, Shahbazi MA, Shatalin YV, Nadal E, Mäkilä E, Salonen J, Kemell M, Correia A, Hirvonen J, Santos HA.

Int J Pharm. 2018 Jan 30;536(1):241-250. doi: 10.1016/j.ijpharm.2017.11.065. Epub 2017 Nov 28.

PMID:
29195917
41.

Whole-Brain Source-Reconstructed MEG-Data Reveal Reduced Long-Range Synchronization in Chronic Schizophrenia.

Hirvonen J, Wibral M, Palva JM, Singer W, Uhlhaas P, Palva S.

eNeuro. 2017 Oct 17;4(5). pii: ENEURO.0338-17.2017. doi: 10.1523/ENEURO.0338-17.2017. eCollection 2017 Sep-Oct.

42.

Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles, and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics.

Liu Z, Li Y, Li W, Xiao C, Liu D, Dong C, Zhang M, Mäkilä E, Kemell M, Salonen J, Hirvonen JT, Zhang H, Zhou D, Deng X, Santos HA.

Adv Mater. 2018 Jun;30(24):e1703393. doi: 10.1002/adma.201703393. Epub 2017 Oct 11.

PMID:
29024054
43.

Neuroticism Associates with Cerebral in Vivo Serotonin Transporter Binding Differently in Males and Females.

Tuominen L, Miettunen J, Cannon DM, Drevets WC, Frokjaer VG, Hirvonen J, Ichise M, Jensen PS, Keltikangas-Järvinen L, Klaver JM, Knudsen GM, Takano A, Suhara T, Hietala J.

Int J Neuropsychopharmacol. 2017 Dec 1;20(12):963-970. doi: 10.1093/ijnp/pyx071.

44.

Competence-Based Pharmacy Education in the University of Helsinki.

Katajavuori N, Salminen O, Vuorensola K, Huhtala H, Vuorela P, Hirvonen J.

Pharmacy (Basel). 2017 Jun 1;5(2). pii: E29. doi: 10.3390/pharmacy5020029.

45.

The Second Round of the PHAR-QA Survey of Competences for Pharmacy Practice.

Atkinson J, De Paepe K, Pozo AS, Rekkas D, Volmer D, Hirvonen J, Bozic B, Skowron A, Mircioiu C, Marcincal A, Koster A, Wilson K, van Schravendijk C.

Pharmacy (Basel). 2016 Sep 21;4(3). pii: E27. doi: 10.3390/pharmacy4030027.

46.

Functionalization of carboxylated lignin nanoparticles for targeted and pH-responsive delivery of anticancer drugs.

Figueiredo P, Ferro C, Kemell M, Liu Z, Kiriazis A, Lintinen K, Florindo HF, Yli-Kauhaluoma J, Hirvonen J, Kostiainen MA, Santos HA.

Nanomedicine (Lond). 2017 Nov;12(21):2581-2596. doi: 10.2217/nnm-2017-0219. Epub 2017 Sep 29.

PMID:
28960138
47.

Current developments and applications of microfluidic technology toward clinical translation of nanomedicines.

Liu D, Zhang H, Fontana F, Hirvonen JT, Santos HA.

Adv Drug Deliv Rev. 2018 Mar 15;128:54-83. doi: 10.1016/j.addr.2017.08.003. Epub 2017 Aug 8. Review.

PMID:
28801093
48.

Accuracy of 837 pedicle screw positions in degenerative lumbar spine with conventional open surgery evaluated by computed tomography.

Saarenpää I, Laine T, Hirvonen J, Hurme S, Kotilainen E, Rinne J, Korhonen K, Frantzén J.

Acta Neurochir (Wien). 2017 Oct;159(10):2011-2017. doi: 10.1007/s00701-017-3289-7. Epub 2017 Aug 10.

PMID:
28799104
49.

Erratum. Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese. Diabetes 2013;62:2747-2751.

Tuulari JJ, Karlsson HK, Hirvonen J, Hannukainen JC, Bucci M, Helmiö M, Ovaska J, Soinio M, Salminen P, Savisto N, Nummenmaa L, Nuutila P.

Diabetes. 2017 Oct;66(10):2724. doi: 10.2337/db17-er10a. Epub 2017 Aug 1. No abstract available.

50.

Feeding Releases Endogenous Opioids in Humans.

Tuulari JJ, Tuominen L, de Boer FE, Hirvonen J, Helin S, Nuutila P, Nummenmaa L.

J Neurosci. 2017 Aug 23;37(34):8284-8291. doi: 10.1523/JNEUROSCI.0976-17.2017. Epub 2017 Jul 26.

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