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Items: 19

1.

Applicability of the dual isotopes δ15N and δ18O to identify nitrate in groundwater beneath irrigated cropland.

Spalding RF, Hirsh AJ, Exner ME, Little NA, Kloppenborg KL.

J Contam Hydrol. 2019 Jan;220:128-135. doi: 10.1016/j.jconhyd.2018.12.004. Epub 2018 Dec 21.

2.

Nebraska's groundwater legacy: Nitrate contamination beneath irrigated cropland.

Exner ME, Hirsh AJ, Spalding RF.

Water Resour Res. 2014 May;50(5):4474-4489. Epub 2014 May 29.

3.

Airway drug pharmacokinetics via analysis of exhaled breath condensate.

Esther CR Jr, Boucher RC, Johnson MR, Ansede JH, Donn KH, O'Riordan TG, Ghio AJ, Hirsh AJ.

Pulm Pharmacol Ther. 2014 Feb;27(1):76-82. doi: 10.1016/j.pupt.2013.07.009. Epub 2013 Aug 7.

4.

Risk-managed approach for routing petroleum pipelines: Keystone XL pipeline, Nebraska.

Spalding RF, Hirsh AJ.

Environ Sci Technol. 2012 Dec 4;46(23):12754-8. doi: 10.1021/es303238z. Epub 2012 Nov 15.

PMID:
23134326
5.

Effect of topically applied epithelial sodium channel inhibitors on tear production in normal mice and in mice with induced aqueous tear deficiency.

Thelin WR, Johnson MR, Hirsh AJ, Kublin CL, Zoukhri D.

J Ocul Pharmacol Ther. 2012 Aug;28(4):433-8. doi: 10.1089/jop.2011.0157. Epub 2012 Mar 28.

6.

A2B adenosine receptors regulate the mucus clearance component of the lung's innate defense system.

Rollins BM, Burn M, Coakley RD, Chambers LA, Hirsh AJ, Clunes MT, Lethem MI, Donaldson SH, Tarran R.

Am J Respir Cell Mol Biol. 2008 Aug;39(2):190-7. doi: 10.1165/rcmb.2007-0450OC. Epub 2008 Mar 26.

7.

Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease.

Hirsh AJ, Zhang J, Zamurs A, Fleegle J, Thelin WR, Caldwell RA, Sabater JR, Abraham WM, Donowitz M, Cha B, Johnson KB, St George JA, Johnson MR, Boucher RC.

J Pharmacol Exp Ther. 2008 Apr;325(1):77-88. doi: 10.1124/jpet.107.130443. Epub 2008 Jan 24.

PMID:
18218832
8.

Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.

Hirsh AJ, Stonebraker JR, van Heusden CA, Lazarowski ER, Boucher RC, Picher M.

Biochemistry. 2007 Sep 11;46(36):10373-83. Epub 2007 Aug 15.

PMID:
17696452
9.

Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.

Hirsh AJ, Molino BF, Zhang J, Astakhova N, Geiss WB, Sargent BJ, Swenson BD, Usyatinsky A, Wyle MJ, Boucher RC, Smith RT, Zamurs A, Johnson MR.

J Med Chem. 2006 Jul 13;49(14):4098-115.

PMID:
16821771
10.

Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease.

Hirsh AJ, Sabater JR, Zamurs A, Smith RT, Paradiso AM, Hopkins S, Abraham WM, Boucher RC.

J Pharmacol Exp Ther. 2004 Dec;311(3):929-38. Epub 2004 Jul 23.

PMID:
15273255
11.

Cytokine secretion by cystic fibrosis airway epithelial cells.

Becker MN, Sauer MS, Muhlebach MS, Hirsh AJ, Wu Q, Verghese MW, Randell SH.

Am J Respir Crit Care Med. 2004 Mar 1;169(5):645-53. Epub 2003 Dec 11.

PMID:
14670800
12.

Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways.

Picher M, Burch LH, Hirsh AJ, Spychala J, Boucher RC.

J Biol Chem. 2003 Apr 11;278(15):13468-79. Epub 2003 Jan 30.

13.

Altering airway surface liquid volume: inhalation therapy with amiloride and hyperosmotic agents.

Hirsh AJ.

Adv Drug Deliv Rev. 2002 Dec 5;54(11):1445-62. Review.

PMID:
12458154
14.

The CF salt controversy: in vivo observations and therapeutic approaches.

Tarran R, Grubb BR, Parsons D, Picher M, Hirsh AJ, Davis CW, Boucher RC.

Mol Cell. 2001 Jul;8(1):149-58.

16.

Inhibition of glucose absorption in the rat jejunum: a novel action of alpha-D-glucosidase inhibitors.

Hirsh AJ, Yao SY, Young JD, Cheeseman CI.

Gastroenterology. 1997 Jul;113(1):205-11.

PMID:
9207279
17.

Effect of cholecystokinin and related peptides on jejunal transepithelial hexose transport in the Sprague-Dawley rat.

Hirsh AJ, Tsang R, Kammila S, Cheeseman CI.

Am J Physiol. 1996 Nov;271(5 Pt 1):G755-61.

PMID:
8944688
18.

Calcium mobilization and isometric tension in bovine tracheal smooth muscle: effects of salbutamol and histamine.

Hirsh AJ, Benishin CG, Jones RL, Pang PK, Man SF.

Cell Calcium. 1996 Jan;19(1):73-81.

PMID:
8653757
19.

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