Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 63

1.

Adeno-Associated Virus Serotype-Specific Inverted Terminal Repeat Sequence Role in Vector Transgene Expression.

Earley LF, Conatser LM, Lue VM, Dobbins AL, Li C, Hirsch ML, Samulski RJ.

Hum Gene Ther. 2020 Feb;31(3-4):151-162. doi: 10.1089/hum.2019.274.

PMID:
31914802
2.

AAV-mediated expression of HLA-G1/5 reduces severity of experimental autoimmune uveitis.

Crabtree E, Song L, Llanga T, Bower JJ, Cullen M, Salmon JH, Hirsch ML, Gilger BC.

Sci Rep. 2019 Dec 27;9(1):19864. doi: 10.1038/s41598-019-56462-3.

3.

Gene Delivery to Human Limbal Stem Cells Using Viral Vectors.

Song L, Song Z, Fry NJ, Conatser L, Llanga T, Mei H, Kafri T, Hirsch ML.

Hum Gene Ther. 2019 Nov;30(11):1336-1348. doi: 10.1089/hum.2019.071. Epub 2019 Sep 25.

PMID:
31392914
4.

Serotype survey of AAV gene delivery via subconjunctival injection in mice.

Song L, Llanga T, Conatser LM, Zaric V, Gilger BC, Hirsch ML.

Gene Ther. 2018 Sep;25(6):402-414. doi: 10.1038/s41434-018-0035-6. Epub 2018 Aug 2.

PMID:
30072815
5.

Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction.

Shao W, Earley LF, Chai Z, Chen X, Sun J, He T, Deng M, Hirsch ML, Ting J, Samulski RJ, Li C.

JCI Insight. 2018 Jun 21;3(12). pii: 120474. doi: 10.1172/jci.insight.120474. eCollection 2018 Jun 21.

6.

Inhibition of antigen presentation during AAV gene therapy using virus peptides.

Shao W, Chen X, Samulski RJ, Hirsch ML, Li C.

Hum Mol Genet. 2018 Feb 15;27(4):601-613. doi: 10.1093/hmg/ddx427.

7.

AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis.

Hirsch ML, Conatser LM, Smith SM, Salmon JH, Wu J, Buglak NE, Davis R, Gilger BC.

Sci Rep. 2017 Dec 19;7(1):17840. doi: 10.1038/s41598-017-18002-9.

8.

Structure-Based Designed Nano-Dysferlin Significantly Improves Dysferlinopathy in BLA/J Mice.

Llanga T, Nagy N, Conatser L, Dial C, Sutton RB, Hirsch ML.

Mol Ther. 2017 Sep 6;25(9):2150-2162. doi: 10.1016/j.ymthe.2017.05.013. Epub 2017 Jun 16.

9.

Adeno-Associated Virus Vectors and Stem Cells: Friends or Foes?

Brown N, Song L, Kollu NR, Hirsch ML.

Hum Gene Ther. 2017 Jun;28(6):450-463. doi: 10.1089/hum.2017.038. Review.

10.

Hip region muscular dystrophy and emergence of motor deficits in dysferlin-deficient Bla/J mice.

Nagy N, Nonneman RJ, Llanga T, Dial CF, Riddick NV, Hampton T, Moy SS, Lehtimäki KK, Ahtoniemi T, Puoliväli J, Windish H, Albrecht D, Richard I, Hirsch ML.

Physiol Rep. 2017 Mar;5(6). pii: e13173. doi: 10.14814/phy2.13173.

11.

Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells.

MacLeod DT, Antony J, Martin AJ, Moser RJ, Hekele A, Wetzel KJ, Brown AE, Triggiano MA, Hux JA, Pham CD, Bartsevich VV, Turner CA, Lape J, Kirkland S, Beard CW, Smith J, Hirsch ML, Nicholson MG, Jantz D, McCreedy B.

Mol Ther. 2017 Apr 5;25(4):949-961. doi: 10.1016/j.ymthe.2017.02.005. Epub 2017 Feb 23.

12.

Direct interaction of human serum proteins with AAV virions to enhance AAV transduction: immediate impact on clinical applications.

Wang M, Sun J, Crosby A, Woodard K, Hirsch ML, Samulski RJ, Li C.

Gene Ther. 2017 Jan;24(1):49-59. doi: 10.1038/gt.2016.75. Epub 2016 Nov 11.

13.

Correction: Low-field thermal mixing in [1-(13)C] pyruvic acid for brute-force hyperpolarization.

Peat DT, Hirsch ML, Gadian DG, Horsewill AJ, Owers-Bradley JR, Kempf JG.

Phys Chem Chem Phys. 2016 Sep 28;18(36):25764. doi: 10.1039/c6cp90225a. Epub 2016 Sep 6.

PMID:
27603570
14.

Low-field thermal mixing in [1-(13)C] pyruvic acid for brute-force hyperpolarization.

Peat DT, Hirsch ML, Gadian DG, Horsewill AJ, Owers-Bradley JR, Kempf JG.

Phys Chem Chem Phys. 2016 Jul 28;18(28):19173-82. doi: 10.1039/c6cp02853e. Epub 2016 Jun 30.

PMID:
27362505
15.

AAV Vectorization of DSB-mediated Gene Editing Technologies.

Moser RJ, Hirsch ML.

Curr Gene Ther. 2016;16(3):207-19. Review.

PMID:
27280971
16.

Identification and Validation of Small Molecules That Enhance Recombinant Adeno-associated Virus Transduction following High-Throughput Screens.

Nicolson SC, Li C, Hirsch ML, Setola V, Samulski RJ.

J Virol. 2016 Jul 27;90(16):7019-7031. doi: 10.1128/JVI.02953-15. Print 2016 Aug 15.

17.

AAV Gene Therapy for MPS1-associated Corneal Blindness.

Vance M, Llanga T, Bennett W, Woodard K, Murlidharan G, Chungfat N, Asokan A, Gilger B, Kurtzberg J, Samulski RJ, Hirsch ML.

Sci Rep. 2016 Feb 22;6:22131. doi: 10.1038/srep22131.

18.

Adeno-associated virus (AAV) gene delivery in stem cell therapy.

Brown NJ, Hirsch ML.

Discov Med. 2015 Nov;20(111):333-42. Review.

19.

Delivering Transgenic DNA Exceeding the Carrying Capacity of AAV Vectors.

Hirsch ML, Wolf SJ, Samulski RJ.

Methods Mol Biol. 2016;1382:21-39. doi: 10.1007/978-1-4939-3271-9_2.

20.

Transport and imaging of brute-force (13)C hyperpolarization.

Hirsch ML, Smith BA, Mattingly M, Goloshevsky AG, Rosay M, Kempf JG.

J Magn Reson. 2015 Dec;261:87-94. doi: 10.1016/j.jmr.2015.09.017. Epub 2015 Oct 24.

PMID:
26540650
21.

Adeno-associated Virus as a Mammalian DNA Vector.

Salganik M, Hirsch ML, Samulski RJ.

Microbiol Spectr. 2015 Aug;3(4). doi: 10.1128/microbiolspec.MDNA3-0052-2014. Review.

22.

Brute-Force Hyperpolarization for NMR and MRI.

Hirsch ML, Kalechofsky N, Belzer A, Rosay M, Kempf JG.

J Am Chem Soc. 2015 Jul 8;137(26):8428-34. doi: 10.1021/jacs.5b01252. Epub 2015 Jun 29.

PMID:
26098752
23.

Adeno-Associated Virus Vector Mediated Delivery of the HBV Genome Induces Chronic Hepatitis B Virus Infection and Liver Fibrosis in Mice.

Ye L, Yu H, Li C, Hirsch ML, Zhang L, Samulski RJ, Li W, Liu Z.

PLoS One. 2015 Jun 15;10(6):e0130052. doi: 10.1371/journal.pone.0130052. eCollection 2015.

24.

A comparison of AAV strategies distinguishes overlapping vectors for efficient systemic delivery of the 6.2 kb Dysferlin coding sequence.

Pryadkina M, Lostal W, Bourg N, Charton K, Roudaut C, Hirsch ML, Richard I.

Mol Ther Methods Clin Dev. 2015 Mar 25;2:15009. doi: 10.1038/mtm.2015.9. eCollection 2015.

25.

Adeno-associated virus inverted terminal repeats stimulate gene editing.

Hirsch ML.

Gene Ther. 2015 Feb;22(2):190-5. doi: 10.1038/gt.2014.109. Epub 2014 Dec 11.

26.

AAV-mediated gene editing via double-strand break repair.

Hirsch ML, Samulski RJ.

Methods Mol Biol. 2014;1114:291-307. doi: 10.1007/978-1-62703-761-7_19.

27.

Promyelocytic leukemia protein is a cell-intrinsic factor inhibiting parvovirus DNA replication.

Mitchell AM, Hirsch ML, Li C, Samulski RJ.

J Virol. 2014 Jan;88(2):925-36. doi: 10.1128/JVI.02922-13. Epub 2013 Nov 6.

28.

Oversized AAV transductifon is mediated via a DNA-PKcs-independent, Rad51C-dependent repair pathway.

Hirsch ML, Li C, Bellon I, Yin C, Chavala S, Pryadkina M, Richard I, Samulski RJ.

Mol Ther. 2013 Dec;21(12):2205-16. doi: 10.1038/mt.2013.184. Epub 2013 Aug 13.

29.
30.

Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.

Li C, Diprimio N, Bowles DE, Hirsch ML, Monahan PE, Asokan A, Rabinowitz J, Agbandje-McKenna M, Samulski RJ.

J Virol. 2012 Aug;86(15):7752-9. doi: 10.1128/JVI.00675-12. Epub 2012 May 16.

31.

Three-dimensional multipotent progenitor cell aggregates for expansion, osteogenic differentiation and 'in vivo' tracing with AAV vector serotype 6.

Ferreira JR, Hirsch ML, Zhang L, Park Y, Samulski RJ, Hu WS, Ko CC.

Gene Ther. 2013 Feb;20(2):158-68. doi: 10.1038/gt.2012.16. Epub 2012 Mar 8.

32.

Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs.

Ellis BL, Hirsch ML, Porter SN, Samulski RJ, Porteus MH.

Gene Ther. 2013 Jan;20(1):35-42. doi: 10.1038/gt.2011.211. Epub 2012 Jan 19.

33.

Viral single-strand DNA induces p53-dependent apoptosis in human embryonic stem cells.

Hirsch ML, Fagan BM, Dumitru R, Bower JJ, Yadav S, Porteus MH, Pevny LH, Samulski RJ.

PLoS One. 2011;6(11):e27520. doi: 10.1371/journal.pone.0027520. Epub 2011 Nov 17.

34.

The prevalence of human parvovirus B19 DNA and antibodies in blood donors from four Chinese blood centers.

Ke L, He M, Li C, Liu Y, Gao L, Yao F, Li J, Bi X, Lv Y, Wang J, Hirsch ML, Li W.

Transfusion. 2011 Sep;51(9):1909-18. doi: 10.1111/j.1537-2995.2011.03067.x. Epub 2011 Mar 7.

PMID:
21382040
35.

Proteasome inhibitors enhance gene delivery by AAV virus vectors expressing large genomes in hemophilia mouse and dog models: a strategy for broad clinical application.

Monahan PE, Lothrop CD, Sun J, Hirsch ML, Kafri T, Kantor B, Sarkar R, Tillson DM, Elia JR, Samulski RJ.

Mol Ther. 2010 Nov;18(11):1907-16. doi: 10.1038/mt.2010.170. Epub 2010 Aug 10.

36.

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM.

Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210.

37.

Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair.

Hirsch ML, Green L, Porteus MH, Samulski RJ.

Gene Ther. 2010 Sep;17(9):1175-80. doi: 10.1038/gt.2010.65. Epub 2010 May 13.

38.

Little vector, big gene transduction: fragmented genome reassembly of adeno-associated virus.

Hirsch ML, Agbandje-McKenna M, Samulski RJ.

Mol Ther. 2010 Jan;18(1):6-8. doi: 10.1038/mt.2009.280. No abstract available.

39.

AAV recombineering with single strand oligonucleotides.

Hirsch ML, Storici F, Li C, Choi VW, Samulski RJ.

PLoS One. 2009 Nov 2;4(11):e7705. doi: 10.1371/journal.pone.0007705.

40.

Normal vaginal microflora during use of various forms of catamenial protection.

Onderdonk AB, Delaney ML, Zamarchi GR, Hirsch ML, Munoz A, Kass EH.

Rev Infect Dis. 1989 Jan-Feb;11 Suppl 1:S61-7.

PMID:
2928653
41.

Qualitative assessment of vaginal microflora during use of tampons of various compositions.

Onderdonk AB, Zamarchi GR, Rodriguez ML, Hirsch ML, Muñoz A, Kass EH.

Appl Environ Microbiol. 1987 Dec;53(12):2779-84.

42.

Quantitative assessment of vaginal microflora during use of tampons of various compositions.

Onderdonk AB, Zamarchi GR, Rodriguez ML, Hirsch ML, Muñoz A, Kass EH.

Appl Environ Microbiol. 1987 Dec;53(12):2774-8.

43.

An annotated bibliography of toxic shock syndrome.

Hirsch ML, Kass EH.

Rev Infect Dis. 1986 Jan-Feb;8 Suppl 1:S1-104. No abstract available.

PMID:
3515499
44.

[Separation of the enzymes playing a role in the division of biosynthesis pathways of uracil and arginine in Coprinus radiatus].

Hirsch ML.

C R Acad Hebd Seances Acad Sci D. 1968 Oct 28;267(18):1473-6. French. No abstract available.

PMID:
4973108
45.

Laboratory-acquired North American blastomycosis.

Denton JF, Di Salvo AF, Hirsch ML.

JAMA. 1967 Mar 20;199(12):935-6. No abstract available.

PMID:
6071564
46.

[Study of the synthesis of proteins by a subcellular fraction of Escherichia coli: role of polynucleotide-phosphorylase].

NISMAN B, FUKUHARA H, HIRSCH ML.

C R Hebd Seances Acad Sci. 1960 Jul 25;251:602-4. French. No abstract available.

PMID:
13729240
47.

Gastric hemorrhage in diabetic coma.

HIRSCH ML.

Diabetes. 1960 Mar-Apr;9:94-6. No abstract available.

PMID:
14401984
48.

[Study of activation & incorporation of amino acids by enzymatic fractions of Escherichia coli].

NISMAN B, HIRSCH ML.

Ann Inst Pasteur (Paris). 1958 Nov;95(5):615-36. French. No abstract available.

PMID:
13606513
49.

[Inhibition of growth in auxotrophic mutants of Escherichia coli requiring homoserine by alpha-amino-delta-hydroxyvaleric acid].

HIRSCH ML.

Ann Inst Pasteur (Paris). 1957 Aug;93(2):199-209. French. No abstract available.

PMID:
13470435
50.

[Investigation on incorporation of amino acids into lysates of Micrococcus lysodeikticus. III. Incorporation of valine-C14 and of methionine-S35].

NISMAN B, HIRSCH ML, MARMUR J, COUSIN D.

C R Hebd Seances Acad Sci. 1955 Nov 7;241(19):1349-51. French. No abstract available.

PMID:
13277222

Supplemental Content

Loading ...
Support Center