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Immunologic Clearance of a BK Virus-associated Metastatic Renal Allograft Carcinoma.

Meier RPH, Müller YD, Dietrich PY, Tille JC, Nikolaev S, Sartori A, Labidi-Galy I, Ernandez T, Kaur A, Hirsch HH, McKee TA, Toso C, Villard J, Berney T.

Transplantation. 2020 Feb 21. doi: 10.1097/TP.0000000000003193. [Epub ahead of print]


Presentation of BK polyomavirus-associated hemorrhagic cystitis after allogeneic hematopoietic cell transplantation.

Imlay H, Xie H, Leisenring WM, Duke ER, Kimball LE, Huang ML, Pergam SA, Hill JA, Jerome KR, Milano F, Nichols WG, Pang PS, Hirsch HH, Limaye AP, Boeckh M.

Blood Adv. 2020 Feb 25;4(4):617-628. doi: 10.1182/bloodadvances.2019000802.


2019-novel Coronavirus (2019-nCoV): estimating the case fatality rate - a word of caution.

Battegay M, Kuehl R, Tschudin-Sutter S, Hirsch HH, Widmer AF, Neher RA.

Swiss Med Wkly. 2020 Feb 7;150:w20203. doi: 10.4414/smw.2020.20203. eCollection 2020 Jan 27. No abstract available.


Repeated Syphilis Episodes in HIV-Infected Men Who Have Sex With Men: A Multicenter Prospective Cohort Study on Risk Factors and the Potential Role of Syphilis Immunity.

Roth JA, Franzeck FC, Balakrishna S, Lautenschlager S, Thurnheer MC, Trellu LT, Cavassini M, Vernazza P, Bernasconi E, Braun D, Kouyos RD, Battegay M; Swiss HIV Cohort Study (SHCS) .

Open Forum Infect Dis. 2020 Jan 12;7(1):ofaa019. doi: 10.1093/ofid/ofaa019. eCollection 2020 Jan.


Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy.

Barceló C, Guidi M, Thorball CW, Hammer C, Chaouch A, Scherrer AU, Hasse B, Cavassini M, Furrer H, Calmy A, Haubitz S, Bernasconi E, Buclin T, Fellay J, Tarr PE, Csajka C; Swiss HIV Cohort Study .

Open Forum Infect Dis. 2020 Jan 22;7(1):ofz464. doi: 10.1093/ofid/ofz464. eCollection 2020 Jan.


BK Polyomavirus-specific T Cells as a Diagnostic and Prognostic Marker for BK Polyomavirus Infections After Pediatric Kidney Transplantation.

Ahlenstiel-Grunow T, Sester M, Sester U, Hirsch HH, Pape L.

Transplantation. 2020 Jan 23. doi: 10.1097/TP.0000000000003133. [Epub ahead of print]


Revisiting cytomegalovirus serostatus and replication as risk factors for inferior long-term outcomes in the current era of renal transplantation.

Bischof N, Wehmeier C, Dickenmann M, Hirt-Minkowski P, Amico P, Steiger J, Naegele K, Hirsch HH, Schaub S.

Nephrol Dial Transplant. 2020 Feb 1;35(2):346-356. doi: 10.1093/ndt/gfz268.


Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor.

Lorentzen EM, Henriksen S, Kaur A, Kro GB, Hammarström C, Hirsch HH, Midtvedt K, Rinaldo CH.

Virol J. 2020 Jan 10;17(1):5. doi: 10.1186/s12985-019-1275-9.


Burden and Timeline of Infectious Diseases in the First Year After Solid Organ Transplantation in the Swiss Transplant Cohort Study.

van Delden C, Stampf S, Hirsch HH, Manuel O, Meylan P, Cusini A, Hirzel C, Khanna N, Weisser M, Garzoni C, Boggian K, Berger C, Nadal D, Koller M, Saccilotto R, Mueller NJ; Swiss Transplant Cohort Study.

Clin Infect Dis. 2020 Jan 9. pii: ciz1113. doi: 10.1093/cid/ciz1113. [Epub ahead of print]


A Phase 2b, Randomized, Double-blind, Placebo-Controlled Multicenter Study Evaluating Antiviral Effects, Pharmacokinetics, Safety, and Tolerability of Presatovir in Hematopoietic Cell Transplant Recipients with Respiratory Syncytial Virus (RSV) Infection of the Lower Respiratory Tract.

Marty FM, Chemaly RF, Mullane KM, Lee DG, Hirsch HH, Small CB, Bergeron A, Shoham S, Ljungman P, Waghmare A, Blanchard E, Kim YJ, McKevitt M, Porter DP, Jordan R, Guo Y, German P, Boeckh M, Watkins TR, Chien JW, Dadwal SS.

Clin Infect Dis. 2019 Dec 3. pii: ciz1167. doi: 10.1093/cid/ciz1167. [Epub ahead of print]


Polypharmacy, Drug-Drug Interactions, and Inappropriate Drugs: New Challenges in the Aging Population With HIV.

Courlet P, Livio F, Guidi M, Cavassini M, Battegay M, Stoeckle M, Buclin T, Alves Saldanha S, Csajka C, Marzolini C, Decosterd L; Swiss HIV Cohort Study .

Open Forum Infect Dis. 2019 Dec 21;6(12):ofz531. doi: 10.1093/ofid/ofz531. eCollection 2019 Dec.


Vitamin D deficiency is common in kidney transplant recipients, but is not associated with infections after transplantation.

Schreiber PW, Kusejko K, Bischoff-Ferrari HA, Boggian K, Bonani M, van Delden C, Enriquez N, Fehr T, Garzoni C, Hirsch HH, Hirzel C, Manuel O, Meylan P, Saleh L, Weisser M, Mueller NJ; Swiss Transplant Cohort Study (STCS).

Clin Transplant. 2020 Feb;34(2):e13778. doi: 10.1111/ctr.13778. Epub 2020 Jan 22.


How helpful are the European AIDS Clinical Society cognitive screening questions in predicting cognitive impairment in an aging, well-treated HIV-positive population?

Metral M, Nadin I, Locatelli I, Tarr PE, Calmy A, Kovari H, Brugger P, Cusini A, Gutbrod K, Schmid P, Schwind M, Kunze U, Di Benedetto C, Pignatti R, Du Pasquier R, Darling K, Cavassini M; Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) study group, Swiss HIV Cohort Study.

HIV Med. 2019 Dec 27. doi: 10.1111/hiv.12828. [Epub ahead of print]


Chemsex drugs on the rise: a longitudinal analysis of the Swiss HIV Cohort Study from 2007 to 2017.

Hampel B, Kusejko K, Kouyos RD, Böni J, Flepp M, Stöckle M, Conen A, Béguelin C, Künzler-Heule P, Nicca D, Schmidt AJ, Nguyen H, Delaloye J, Rougemont M, Bernasconi E, Rauch A, Günthard HF, Braun DL, Fehr J; Swiss HIV Cohort Study group.

HIV Med. 2019 Dec 18. doi: 10.1111/hiv.12821. [Epub ahead of print]


A phase 2, randomized, double-blind, placebo-controlled trial of presatovir for the treatment of respiratory syncytial virus upper respiratory tract infection in hematopoietic-cell transplant recipients.

Chemaly RF, Dadwal SS, Bergeron A, Ljungman P, Kim YJ, Cheng GS, Pipavath SN, Limaye AP, Blanchard E, Winston DJ, Stiff PJ, Zuckerman T, Lachance S, Rahav G, Small CB, Mullane KM, Patron RL, Lee DG, Hirsch HH, Waghmare A, McKevitt M, Jordan R, Guo Y, German P, Porter DP, Gossage DL, Watkins TR, Marty FM, Chien JW, Boeckh M.

Clin Infect Dis. 2019 Dec 3. pii: ciz1166. doi: 10.1093/cid/ciz1166. [Epub ahead of print]


Quantification of plasma BK polyomavirus loads is affected by sequence variability, amplicon length, and non-encapsidated viral DNA genome fragments.

Leuzinger K, Naegele K, Schaub S, Hirsch HH.

J Clin Virol. 2019 Dec;121:104210. doi: 10.1016/j.jcv.2019.104210. Epub 2019 Nov 9. No abstract available.


Antibodies against HPV16E6 oncoprotein in the Swiss HIV cohort study: Kinetics and anal cancer risk prediction.

Combes JD, Clifford GM, Günthard HF, Hauser C, Darling KEA, Valladares P, Battegay M, Waldeck F, Bernasconi E, Bertisch B, Hirsch HH, Brenner N, Waterboer T, Scherrer AU; Swiss HIV Cohort Study.

Int J Cancer. 2019 Nov 12. doi: 10.1002/ijc.32784. [Epub ahead of print]


Syphilis Reactivates Latent Epstein-Barr Virus Reservoir via Toll-Like Receptor 2 and B-Cell Receptor Activation.

Hirsiger JR, Fuchs PS, Häusermann P, Müller-Durovic B, Daikeler T, Recher M, Hirsch HH, Terracciano L, Berger CT.

Open Forum Infect Dis. 2019 Jul 3;6(9):ofz317. doi: 10.1093/ofid/ofz317. eCollection 2019 Sep.


Can HLA-B51 Protect Against BKPyV-DNAemia?

Willhelm M, Wilk S, Kaur A, Hirsch HH; Swiss Transplant Cohort Study.

Transplantation. 2019 Nov;103(11):e384-e385. doi: 10.1097/TP.0000000000002731. No abstract available.


Rates and predictors of switching to tenofovir alafenamide-containing ART in a nationwide cohort.

Surial B, Cavassini M, Calmy A, Fehr J, Stöckle M, Bernasconi E, Roth B, Fux CA, Kovari H, Furrer H, Rauch A, Wandeler G; Swiss HIV Cohort Study.

BMC Infect Dis. 2019 Oct 10;19(1):834. doi: 10.1186/s12879-019-4454-9.


BK polyomavirus-specific antibody and T-cell responses in kidney transplantation: update.

Kaur A, Wilhelm M, Wilk S, Hirsch HH.

Curr Opin Infect Dis. 2019 Dec;32(6):575-583. doi: 10.1097/QCO.0000000000000602.


Management of allergy transfer upon solid organ transplantation.

Muller YD, Vionnet J, Beyeler F, Eigenmann P, Caubet JC, Villard J, Berney T, Scherer K, Spertini F, Fricker MP, Lang C, Schmid-Grendelmeier P, Benden C, Roux Lombard P, Aubert V, Immer F, Pascual M, Harr T; Swiss Transplant Cohort Study.

Am J Transplant. 2020 Mar;20(3):834-843. doi: 10.1111/ajt.15601. Epub 2019 Oct 19.


JC polyomavirus-specific antibody responses in pediatric kidney transplant recipients.

Ylinen E, Miettinen J, Jalanko H, Weissbach FH, Tainio J, Wernli M, Lautenschlager I, Hirsch HH.

Pediatr Transplant. 2019 Dec;23(8):e13586. doi: 10.1111/petr.13586. Epub 2019 Sep 19.


Screening HIV-positive men who have sex with men for hepatitis C re-infection risk: is a single question on condom-use enough? A sensitivity analysis.

Künzler-Heule P, Engberg S, Battegay M, Schmidt AJ, Fierz K, Nguyen H, Kocher A, Nöstlinger C, Hampel B, Stöckle M, Béguelin C, Delaloye J, Schmid P, Flepp M, Rougement M, Braun DL, Fehr J, Nicca D; Swiss HIV Cohort Study (SHCS).

BMC Infect Dis. 2019 Sep 18;19(1):821. doi: 10.1186/s12879-019-4456-7.


Community-Acquired Respiratory Viruses in Transplant Patients: Diversity, Impact, Unmet Clinical Needs.

Ison MG, Hirsch HH.

Clin Microbiol Rev. 2019 Sep 11;32(4). pii: e00042-19. doi: 10.1128/CMR.00042-19. Print 2019 Sep 18. Review.


Mortality from suicide among people living with HIV and the general Swiss population: 1988-2017.

Ruffieux Y, Lemsalu L, Aebi-Popp K, Calmy A, Cavassini M, Fux CA, Günthard HF, Marzolini C, Scherrer A, Vernazza P, Keiser O, Egger M; Swiss HIV Cohort Study and the Swiss National Cohort.

J Int AIDS Soc. 2019 Aug;22(8):e25339. doi: 10.1002/jia2.25339.


Time-course of upper respiratory tract viral infection and COPD exacerbation.

Stolz D, Papakonstantinou E, Grize L, Schilter D, Strobel W, Louis R, Schindler C, Hirsch HH, Tamm M.

Eur Respir J. 2019 Oct 10;54(4). pii: 1900407. doi: 10.1183/13993003.00407-2019. Print 2019 Oct.


Screening for BK polyomavirus DNAemia: What should be done?

Hirsch HH, Randhawa PS.

Clin Transplant. 2019 Oct;33(10):e13672. doi: 10.1111/ctr.13672. Epub 2019 Aug 6. No abstract available.


Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART.

Bachmann N, von Siebenthal C, Vongrad V, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Fellay J, Roth V, Kok YL, Thorball CW, Borghesi A, Parbhoo S, Wieser M, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Rauch A, Hoffmann M, Bernasconi E, Cavassini M, Kouyos RD, Günthard HF, Metzner KJ; Swiss HIV Cohort Study.

Nat Commun. 2019 Jul 19;10(1):3193. doi: 10.1038/s41467-019-10884-9.


Correction to: Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study.

Olsøy IB, Henriksen S, Weissbach FH, Larsen M, Borgen K, Abravanel F, Kamar N, Paulssen EJ, Hirsch HH, Rinaldo CH.

Med Microbiol Immunol. 2019 Dec;208(6):887. doi: 10.1007/s00430-019-00626-5.


Mycoplasma pneumoniae detection in children with respiratory tract infections and influence on management - a retrospective cohort study in Switzerland.

Dierig A, Hirsch HH, Decker ML, Bielicki JA, Heininger U, Ritz N.

Acta Paediatr. 2020 Feb;109(2):375-380. doi: 10.1111/apa.14891. Epub 2019 Jun 27.


Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting.

Barcelo C, Aouri M, Courlet P, Guidi M, Braun DL, Günthard HF, Piso RJ, Cavassini M, Buclin T, Decosterd LA, Csajka C; Swiss HIV Cohort Study .

J Antimicrob Chemother. 2019 Sep 1;74(9):2690-2697. doi: 10.1093/jac/dkz217.


Emtricitabine and lamivudine concentrations in saliva: a simple suitable test for treatment adherence.

Courlet P, Decosterd LA, Brown JA, Alves Saldanha S, Marzolini C, Cavassini M, Stoeckle M, Csajka C, Labhardt ND, Calmy A; Swiss HIV Cohort Study .

J Antimicrob Chemother. 2019 Aug 1;74(8):2468-2470. doi: 10.1093/jac/dkz181. No abstract available.


Why do sub-Saharan Africans present late for HIV care in Switzerland?

Hachfeld A, Darling K, Calmy A, Ledergerber B, Weber R, Battegay M, Wissel K, Di Benedetto C, Fux CA, Tarr PE, Kouyos R, Ruggia LS, Furrer HJ, Wandeler G; Swiss HIV Cohort Study.

HIV Med. 2019 Jul;20(6):418-423. doi: 10.1111/hiv.12727. Epub 2019 May 6.


Antiretroviral Drugs Associated With Subclinical Coronary Artery Disease in the Swiss Human Immunodeficiency Virus Cohort Study.

Kovari H, Calmy A, Doco-Lecompte T, Nkoulou R, Marzel A, Weber R, Kaufmann PA, Buechel RR, Ledergerber B, Tarr PE; Swiss Human Immunodeficiency Virus Cohort Study .

Clin Infect Dis. 2020 Feb 14;70(5):884-889. doi: 10.1093/cid/ciz283.


The rate of mother-to-child transmission of antiretroviral drug-resistant HIV strains is low in the Swiss Mother and Child HIV Cohort Study.

Compagno F, Naegele K, Kahlert CR, Hösli I, Aebi-Popp K, Martinez de Tejada B, Paioni P, Yerly S, Böni J, Battegay M, Rudin C, Hirsch HH, Swiss Hiv Cohort Study.

Swiss Med Wkly. 2019 Apr 4;149:w20059. doi: 10.4414/smw.2019.20059. eCollection 2019 Mar 25.


Prevalence and Clinical Outcomes of Poor Immune Response Despite Virologically Suppressive Antiretroviral Therapy Among Children and Adolescents With Human Immunodeficiency Virus in Europe and Thailand: Cohort Study.

European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) Study Group in EuroCoord .

Clin Infect Dis. 2020 Jan 16;70(3):404-415. doi: 10.1093/cid/ciz253.


Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study.

Olsøy IB, Henriksen S, Weissbach FH, Larsen M, Borgen K, Abravanel F, Kamar N, Paulssen EJ, Hirsch HH, Rinaldo CH.

Med Microbiol Immunol. 2019 Dec;208(6):715-725. doi: 10.1007/s00430-019-00599-5. Epub 2019 Mar 22. Erratum in: Med Microbiol Immunol. 2019 Jun 22;:.


BK polyomavirus in solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.

Hirsch HH, Randhawa PS; AST Infectious Diseases Community of Practice.

Clin Transplant. 2019 Sep;33(9):e13528. doi: 10.1111/ctr.13528. Epub 2019 Apr 10.


Emergence of Drug Resistance in the Swiss HIV Cohort Study Under Potent Antiretroviral Therapy Is Observed in Socially Disadvantaged Patients.

Abela IA, Scherrer AU, Böni J, Yerly S, Klimkait T, Perreau M, Hirsch HH, Furrer H, Calmy A, Schmid P, Cavassini M, Bernasconi E, Günthard HF; Swiss HIV Cohort Study .

Clin Infect Dis. 2020 Jan 2;70(2):297-303. doi: 10.1093/cid/ciz178.


Community-acquired Respiratory Viruses Are a Risk Factor for Chronic Lung Allograft Dysfunction.

Peghin M, Los-Arcos I, Hirsch HH, Codina G, Monforte V, Bravo C, Berastegui C, Jauregui A, Romero L, Cabral E, Ferrer R, Sacanell J, Román A, Len O, Gavaldà J.

Clin Infect Dis. 2019 Sep 13;69(7):1192-1197. doi: 10.1093/cid/ciy1047.


Metagenomic Virome Sequencing in Living Donor and Recipient Kidney Transplant Pairs Revealed JC Polyomavirus Transmission.

Schreiber PW, Kufner V, Hübel K, Schmutz S, Zagordi O, Kaur A, Bayard C, Greiner M, Zbinden A, Capaul R, Böni J, Hirsch HH, Mueller TF, Mueller NJ, Trkola A, Huber M.

Clin Infect Dis. 2019 Aug 30;69(6):987-994. doi: 10.1093/cid/ciy1018.


Reducing calcineurin inhibitor first for treating BK polyomavirus replication after kidney transplantation: long-term outcomes.

Bischof N, Hirsch HH, Wehmeier C, Amico P, Dickenmann M, Hirt-Minkowski P, Steiger J, Menter T, Helmut H, Schaub S.

Nephrol Dial Transplant. 2019 Jul 1;34(7):1240-1250. doi: 10.1093/ndt/gfy346.


Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland.

Bachmann N, von Braun A, Labhardt ND, Kadelka C, Günthard HF, Sekaggya-Wiltshire C, Castelnuovo B, Kambugu A, Lejone TI, Böni J, Yerly S, Perreau M, Klimkait T, Kouyos RD, Fehr J; Swiss HIV Cohort Study.

J Antimicrob Chemother. 2019 Feb 1;74(2):468-472. doi: 10.1093/jac/dky436.


BK polyomavirus viremia and antibody responses of pediatric kidney transplant recipients in Finland.

Miettinen J, Lautenschlager I, Weissbach F, Wernli M, Auvinen E, Mannonen L, Lauronen J, Hirsch HH, Jalanko H.

Pediatr Transplant. 2019 Feb;23(1):e13324. doi: 10.1111/petr.13324. Epub 2018 Nov 16.


Comparing the Cobas Liat Influenza A/B and respiratory syncytial virus assay with multiplex nucleic acid testing.

Gosert R, Naegele K, Hirsch HH.

J Med Virol. 2019 Apr;91(4):582-587. doi: 10.1002/jmv.25344. Epub 2018 Nov 13.


Tracing HIV-1 strains that imprint broadly neutralizing antibody responses.

Kouyos RD, Rusert P, Kadelka C, Huber M, Marzel A, Ebner H, Schanz M, Liechti T, Friedrich N, Braun DL, Scherrer AU, Weber J, Uhr T, Baumann NS, Leemann C, Kuster H, Chave JP, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Metzner KJ, Günthard HF, Trkola A; Swiss HIV Cohort Study.

Nature. 2018 Sep;561(7723):406-410. doi: 10.1038/s41586-018-0517-0. Epub 2018 Sep 10.


BK Polyomavirus MicroRNA Levels in Exosomes Are Modulated by Non-Coding Control Region Activity and Down-Regulate Viral Replication When Delivered to Non-Infected Cells Prior to Infection.

Martelli F, Wu Z, Delbue S, Weissbach FH, Giulioli MC, Ferrante P, Hirsch HH, Giannecchini S.

Viruses. 2018 Aug 30;10(9). pii: E466. doi: 10.3390/v10090466.


Pneumocystis jirovecii pneumonia in solid organ transplant recipients: a descriptive analysis for the Swiss Transplant Cohort.

Neofytos D, Hirzel C, Boely E, Lecompte T, Khanna N, Mueller NJ, Boggian K, Cusini A, Manuel O, van Delden C; Swiss Transplant Cohort Study.

Transpl Infect Dis. 2018 Dec;20(6):e12984. doi: 10.1111/tid.12984. Epub 2018 Sep 19.


Epidemiology of and Risk Factors for BK Polyomavirus Replication and Nephropathy in Pediatric Renal Transplant Recipients: An International CERTAIN Registry Study.

Höcker B, Schneble L, Murer L, Carraro A, Pape L, Kranz B, Oh J, Zirngibl M, Dello Strologo L, Büscher A, Weber LT, Awan A, Pohl M, Bald M, Printza N, Rusai K, Peruzzi L, Topaloglu R, Fichtner A, Krupka K, Köster L, Bruckner T, Schnitzler P, Hirsch HH, Tönshoff B.

Transplantation. 2019 Jun;103(6):1224-1233. doi: 10.1097/TP.0000000000002414.


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