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Items: 1 to 50 of 66

1.

Total Small Vessel Disease Score in Neurologically Healthy Japanese Adults in the Kashima Scan Study.

Yakushiji Y, Charidimou A, Noguchi T, Nishihara M, Eriguchi M, Nanri Y, Kawaguchi A, Hirotsu T, Werring DJ, Hara H.

Intern Med. 2018 Jan 15;57(2):189-196. doi: 10.2169/internalmedicine.8393-16. Epub 2017 Oct 16.

2.

Cyclodextrin-based sustained and controllable release system of insulin utilizing the combination system of self-assembly PEGylation and polypseudorotaxane formation.

Hirotsu T, Higashi T, Motoyama K, Arima H.

Carbohydr Polym. 2017 May 15;164:42-48. doi: 10.1016/j.carbpol.2017.01.074. Epub 2017 Jan 23.

PMID:
28325342
3.

Stabilizing Effects for Antibody Formulations and Safety Profiles of Cyclodextrin Polypseudorotaxane Hydrogels.

Higashi T, Ohshita N, Hirotsu T, Yamashita Y, Motoyama K, Koyama S, Iibuchi R, Uchida T, Mieda S, Handa K, Kimoto T, Arima H.

J Pharm Sci. 2017 May;106(5):1266-1274. doi: 10.1016/j.xphs.2017.01.002. Epub 2017 Jan 12.

PMID:
28089687
4.

Self-Assembly PEGylation Retaining Activity (SPRA) Technology via a Host-Guest Interaction Surpassing Conventional PEGylation Methods of Proteins.

Hirotsu T, Higashi T, Abu Hashim II, Misumi S, Wada K, Motoyama K, Arima H.

Mol Pharm. 2017 Feb 6;14(2):368-376. doi: 10.1021/acs.molpharmaceut.6b00678. Epub 2017 Jan 12.

PMID:
28032772
5.

Establishment of Time- and Cell-Specific RNAi in Caenorhabditis elegans.

Hamakawa M, Hirotsu T.

Methods Mol Biol. 2017;1507:67-79.

PMID:
27832533
6.

Voltage-dependent anion channel (VDAC-1) is required for olfactory sensing in Caenorhabditis elegans.

Uozumi T, Hamakawa M, Deno YK, Nakajo N, Hirotsu T.

Genes Cells. 2015 Oct;20(10):802-16. doi: 10.1111/gtc.12269. Epub 2015 Jul 30.

7.

Effect of exercise at light loads with manipulative resistance on infraspinatus, trapezius (upper fiber) and deltoid (middle fiber) muscle activities in shoulder joint elevation.

Nanba Y, Miyamoto S, Takemasa S, Uesugi M, Inoue Y, Ootani Y, Fujii S, Hirotsu T, Tanaka H.

J Phys Ther Sci. 2015 Mar;27(3):627-9. doi: 10.1589/jpts.27.627. Epub 2015 Mar 31. Retraction in: J Phys Ther Sci. 2015 Oct;27(10):r1.

8.

Design and Evaluation of the Highly Concentrated Human IgG Formulation Using Cyclodextrin Polypseudorotaxane Hydrogels.

Higashi T, Tajima A, Ohshita N, Hirotsu T, Abu Hashim II, Motoyama K, Koyama S, Iibuchi R, Mieda S, Handa K, Kimoto T, Arima H.

AAPS PharmSciTech. 2015 Dec;16(6):1290-8. doi: 10.1208/s12249-015-0309-x. Epub 2015 Mar 17.

9.

A highly accurate inclusive cancer screening test using Caenorhabditis elegans scent detection.

Hirotsu T, Sonoda H, Uozumi T, Shinden Y, Mimori K, Maehara Y, Ueda N, Hamakawa M.

PLoS One. 2015 Mar 11;10(3):e0118699. doi: 10.1371/journal.pone.0118699. eCollection 2015.

10.

A role for Ras in inhibiting circular foraging behavior as revealed by a new method for time and cell-specific RNAi.

Hamakawa M, Uozumi T, Ueda N, Iino Y, Hirotsu T.

BMC Biol. 2015 Jan 21;13:6. doi: 10.1186/s12915-015-0114-8.

11.

Norms of the Mini-Mental state Examination for Japanese subjects that underwent comprehensive brain examinations: the Kashima Scan Study.

Yakushiji Y, Horikawa E, Eriguchi M, Nanri Y, Nishihara M, Hirotsu T, Hara H.

Intern Med. 2014;53(21):2447-53. Epub 2014 Nov 1.

12.

Screening of odor-receptor pairs in Caenorhabditis elegans reveals different receptors for high and low odor concentrations.

Taniguchi G, Uozumi T, Kiriyama K, Kamizaki T, Hirotsu T.

Sci Signal. 2014 Apr 29;7(323):ra39. doi: 10.1126/scisignal.2005136.

PMID:
24782565
13.

Synthesis of trans-2,6-disubstituted cyclohexanones through allylic substitution.

Kobayashi Y, Feng C, Ikoma A, Ogawa N, Hirotsu T.

Org Lett. 2014 Feb 7;16(3):760-3. doi: 10.1021/ol403472y. Epub 2014 Jan 22.

PMID:
24451031
14.

Joint effect of hypertension and lifestyle-related risk factors on the risk of brain microbleeds in healthy individuals.

Hara M, Yakushiji Y, Nannri H, Sasaki S, Noguchi T, Nishiyama M, Hirotsu T, Nakajima J, Hara H.

Hypertens Res. 2013 Sep;36(9):789-94. doi: 10.1038/hr.2013.26. Epub 2013 Apr 11.

PMID:
23575379
15.

Temporally-regulated quick activation and inactivation of Ras is important for olfactory behaviour.

Uozumi T, Hirotsu T, Yoshida K, Yamada R, Suzuki A, Taniguchi G, Iino Y, Ishihara T.

Sci Rep. 2012;2:500. doi: 10.1038/srep00500. Epub 2012 Jul 9.

16.

Distributional impact of brain microbleeds on global cognitive function in adults without neurological disorder.

Yakushiji Y, Noguchi T, Hara M, Nishihara M, Eriguchi M, Nanri Y, Nishiyama M, Hirotsu T, Nakajima J, Kuroda Y, Hara H.

Stroke. 2012 Jul;43(7):1800-5. doi: 10.1161/STROKEAHA.111.647065. Epub 2012 May 10.

17.

Odour concentration-dependent olfactory preference change in C. elegans.

Yoshida K, Hirotsu T, Tagawa T, Oda S, Wakabayashi T, Iino Y, Ishihara T.

Nat Commun. 2012 Mar 13;3:739. doi: 10.1038/ncomms1750.

PMID:
22415830
18.

Behavioral choice between conflicting alternatives is regulated by a receptor guanylyl cyclase, GCY-28, and a receptor tyrosine kinase, SCD-2, in AIA interneurons of Caenorhabditis elegans.

Shinkai Y, Yamamoto Y, Fujiwara M, Tabata T, Murayama T, Hirotsu T, Ikeda DD, Tsunozaki M, Iino Y, Bargmann CI, Katsura I, Ishihara T.

J Neurosci. 2011 Feb 23;31(8):3007-15. doi: 10.1523/JNEUROSCI.4691-10.2011.

19.

Fe-Al layered double hydroxides in bromate reduction: Synthesis and reactivity.

Chitrakar R, Makita Y, Sonoda A, Hirotsu T.

J Colloid Interface Sci. 2011 Feb 15;354(2):798-803. doi: 10.1016/j.jcis.2010.11.010. Epub 2010 Nov 12.

PMID:
21126742
20.

Synthesis of a novel layered double hydroxides [MgAl(4)(OH)(12)](Cl)(2)ยท2.4H(2)O and its anion-exchange properties.

Chitrakar R, Makita Y, Sonoda A, Hirotsu T.

J Hazard Mater. 2011 Jan 30;185(2-3):1435-9. doi: 10.1016/j.jhazmat.2010.10.066. Epub 2010 Oct 23.

PMID:
21074937
21.

Marked cerebral atrophy is correlated with kidney dysfunction in nondisabled adults.

Yakushiji Y, Nanri Y, Hirotsu T, Nishihara M, Hara M, Nakajima J, Eriguchi M, Nishiyama M, Hara H, Node K.

Hypertens Res. 2010 Dec;33(12):1232-7. doi: 10.1038/hr.2010.171. Epub 2010 Oct 14.

PMID:
20944639
22.

Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans.

Yamada K, Hirotsu T, Matsuki M, Butcher RA, Tomioka M, Ishihara T, Clardy J, Kunitomo H, Iino Y.

Science. 2010 Sep 24;329(5999):1647-50. doi: 10.1126/science.1192020.

23.

Uptake properties of phosphate on a novel Zr-modified MgFe-LDH(CO(3)).

Chitrakar R, Tezuka S, Hosokawa J, Makita Y, Sonoda A, Ooi K, Hirotsu T.

J Colloid Interface Sci. 2010 Sep 1;349(1):314-20. doi: 10.1016/j.jcis.2010.05.068. Epub 2010 May 23.

PMID:
20621813
24.

Light-driven thermoelectric conversion based on a carbon nanotube-ionic liquid gel composite.

Miyako E, Nagata H, Funahashi R, Hirano K, Hirotsu T.

ChemSusChem. 2009;2(8):740-2. doi: 10.1002/cssc.200900069. No abstract available.

PMID:
19593839
25.

Ionic liquids on photoinduced nanotube composite arrays as a reaction medium.

Miyako E, Itoh T, Nara Y, Hirotsu T.

Chemistry. 2009 Aug 3;15(31):7520-5. doi: 10.1002/chem.200901348. No abstract available.

PMID:
19569144
26.

A trophic role for Wnt-Ror kinase signaling during developmental pruning in Caenorhabditis elegans.

Hayashi Y, Hirotsu T, Iwata R, Kage-Nakadai E, Kunitomo H, Ishihara T, Iino Y, Kubo T.

Nat Neurosci. 2009 Aug;12(8):981-7. doi: 10.1038/nn.2347. Epub 2009 Jun 28.

PMID:
19561603
27.

Light-triggered thermoelectric conversion based on a carbon nanotube-polymer hybrid gel.

Miyako E, Nagata H, Funahashi R, Hirano K, Hirotsu T.

ChemSusChem. 2009;2(5):419-22. doi: 10.1002/cssc.200900066.

PMID:
19455558
28.

Laser-triggered carbon nanotube microdevice for remote control of biocatalytic reactions.

Miyako E, Nagata H, Hirano K, Hirotsu T.

Lab Chip. 2009 Mar 21;9(6):788-94. doi: 10.1039/b816201h. Epub 2008 Dec 5.

PMID:
19255660
29.

GPC-1, a G protein gamma-subunit, regulates olfactory adaptation in Caenorhabditis elegans.

Yamada K, Hirotsu T, Matsuki M, Kunitomo H, Iino Y.

Genetics. 2009 Apr;181(4):1347-57. doi: 10.1534/genetics.108.099002. Epub 2009 Feb 2.

30.

Lamellar carbon nanosheets function as templates for two-dimensional deposition of tubular titanate.

Peng W, Wang Z, Yoshizawa N, Hatori H, Hirotsu T.

Chem Commun (Camb). 2008 Sep 28;(36):4348-50. doi: 10.1039/b808068b. Epub 2008 Jul 21.

PMID:
18802566
31.

Photodynamic thermoresponsive nanocarbon-polymer gel hybrids.

Miyako E, Nagata H, Hirano K, Hirotsu T.

Small. 2008 Oct;4(10):1711-5. doi: 10.1002/smll.200800601. No abstract available.

PMID:
18770507
32.

Brain microbleeds and global cognitive function in adults without neurological disorder.

Yakushiji Y, Nishiyama M, Yakushiji S, Hirotsu T, Uchino A, Nakajima J, Eriguchi M, Nanri Y, Hara M, Horikawa E, Kuroda Y.

Stroke. 2008 Dec;39(12):3323-8. doi: 10.1161/STROKEAHA.108.516112. Epub 2008 Aug 7.

33.

Carbon nanotube-polymer composite for light-driven microthermal control.

Miyako E, Nagata H, Hirano K, Hirotsu T.

Angew Chem Int Ed Engl. 2008;47(19):3610-3. doi: 10.1002/anie.200800296. No abstract available.

PMID:
18386273
34.

Photoinduced antiviral carbon nanohorns.

Miyako E, Nagata H, Hirano K, Sakamoto K, Makita Y, Nakayama K, Hirotsu T.

Nanotechnology. 2008 Feb 20;19(7):075106. doi: 10.1088/0957-4484/19/7/075106. Epub 2008 Jan 29.

PMID:
21817631
35.

Synthesis and phosphate uptake behavior of Zr4+ incorporated MgAl-layered double hydroxides.

Chitrakar R, Tezuka S, Sonoda A, Sakane K, Ooi K, Hirotsu T.

J Colloid Interface Sci. 2007 Sep 1;313(1):53-63. Epub 2007 May 16.

PMID:
17509605
36.

Adsorption characteristics of nanoporous carbon-silica composites synthesized from graphite oxide by a mechanochemical intercalation method.

Chu YH, Yamagishi M, Wang ZM, Kanoh H, Hirotsu T.

J Colloid Interface Sci. 2007 Aug 15;312(2):186-92. Epub 2007 Apr 13.

PMID:
17498728
37.

Bioconversion of D-psicose to D-tagatose and D-talitol by Mucoraceae fungi.

Yoshihara K, Shinohara Y, Hirotsu T, Izumori K.

J Biosci Bioeng. 2006 Mar;101(3):219-22.

PMID:
16716921
38.

Preparation of cerium-loaded Y-zeolites for removal of organic sulfur compounds from hydrodesulfurizated gasoline and diesel oil.

Xue M, Chitrakar R, Sakane K, Hirotsu T, Ooi K, Yoshimura Y, Toba M, Feng Q.

J Colloid Interface Sci. 2006 Jun 15;298(2):535-42. Epub 2006 Feb 3.

PMID:
16458914
39.

Phosphate adsorption on synthetic goethite and akaganeite.

Chitrakar R, Tezuka S, Sonoda A, Sakane K, Ooi K, Hirotsu T.

J Colloid Interface Sci. 2006 Jun 15;298(2):602-8. Epub 2006 Feb 7.

PMID:
16455102
40.

Selective adsorption of phosphate from seawater and wastewater by amorphous zirconium hydroxide.

Chitrakar R, Tezuka S, Sonoda A, Sakane K, Ooi K, Hirotsu T.

J Colloid Interface Sci. 2006 May 15;297(2):426-33. Epub 2005 Dec 7.

PMID:
16337645
41.

Chitosan productivity enhancement in Rhizopus oryzae YPF-61A by D-psicose.

Yoshihara K, Shinohara Y, Hirotsu T, Izumori K.

J Biosci Bioeng. 2003;95(3):293-7.

PMID:
16233408
42.

MBR-1, a novel helix-turn-helix transcription factor, is required for pruning excessive neurites in Caenorhabditis elegans.

Kage E, Hayashi Y, Takeuchi H, Hirotsu T, Kunitomo H, Inoue T, Arai H, Iino Y, Kubo T.

Curr Biol. 2005 Sep 6;15(17):1554-9.

43.
44.

Adsorption of phosphate from seawater on calcined MgMn-layered double hydroxides.

Chitrakar R, Tezuka S, Sonoda A, Sakane K, Ooi K, Hirotsu T.

J Colloid Interface Sci. 2005 Oct 1;290(1):45-51.

PMID:
15925378
45.

Selective adsorption of thiophene and 1-benzothiophene on metal-ion-exchanged zeolites in organic medium.

Xue M, Chitrakar R, Sakane K, Hirotsu T, Ooi K, Yoshimura Y, Feng Q, Sumida N.

J Colloid Interface Sci. 2005 May 15;285(2):487-92.

PMID:
15837463
46.

Synthesis of nanoporous graphite-derived carbon-silica composites by a mechanochemical intercalation approach.

Chu YH, Wang ZM, Yamagishi M, Kanoh H, Hirotsu T, Zhang YX.

Langmuir. 2005 Mar 15;21(6):2545-51.

PMID:
15752051
47.

Nano-complex formation of cyclodextrin and azobenzene using supercritical carbon dioxide.

Wu M, Yuguchi Y, Kumagai T, Endo T, Hirotsu T.

Chem Commun (Camb). 2004 Jun 7;(11):1288-9. Epub 2004 May 10. No abstract available.

PMID:
15154040
48.

Adoptive immunotherapy for malignant brain tumors using human peripheral blood mononuclear cells activated by the Streptococcal preparation OK-432.

Hirotsu T, Mineta T, Ichinose M, Toda K, Fukuyama K, Tabuchi K.

Neurol Med Chir (Tokyo). 2001 Aug;41(8):387-92.

49.

A classification of circadian blood pressure profiles using a cumulative chi-square technique.

Shimizu K, Hirose N, Hirotsu T, Adachi E.

Scand J Clin Lab Invest. 2000 Dec;60(8):703-12.

PMID:
11218153
50.

The Ras-MAPK pathway is important for olfaction in Caenorhabditis elegans.

Hirotsu T, Saeki S, Yamamoto M, Iino Y.

Nature. 2000 Mar 16;404(6775):289-93. Erratum in: Nature. 2004 Dec 2;432(7017):653.

PMID:
10749212

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