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Items: 1 to 50 of 53

1.

Expression regulation of myo-inositol 3-phosphate synthase 1 (INO1) in determination of phytic acid accumulation in rice grain.

Perera I, Fukushima A, Akabane T, Horiguchi G, Seneweera S, Hirotsu N.

Sci Rep. 2019 Oct 16;9(1):14866. doi: 10.1038/s41598-019-51485-2.

2.

Baloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes.

Hirotsu N, Sakaguchi H, Sato C, Ishibashi T, Baba K, Omoto S, Shishido T, Tsuchiya K, Hayden FG, Uehara T, Watanabe A.

Clin Infect Dis. 2019 Sep 20. pii: ciz908. doi: 10.1093/cid/ciz908. [Epub ahead of print]

PMID:
31538644
3.

Antibody dynamics in Japanese paediatric patients with influenza A infection treated with neuraminidase inhibitors in a randomised trial.

Hirotsu N, Saisho Y, Hasegawa T, Kitano M, Shishido T.

Sci Rep. 2019 Aug 15;9(1):11891. doi: 10.1038/s41598-019-47884-0.

4.

Treatment-Emergent Influenza Variant Viruses With Reduced Baloxavir Susceptibility: Impact on Clinical and Virologic Outcomes in Uncomplicated Influenza.

Uehara T, Hayden FG, Kawaguchi K, Omoto S, Hurt AC, De Jong MD, Hirotsu N, Sugaya N, Lee N, Baba K, Shishido T, Tsuchiya K, Portsmouth S, Kida H.

J Infect Dis. 2019 Jul 16. pii: jiz244. doi: 10.1093/infdis/jiz244. [Epub ahead of print]

PMID:
31309975
5.

Photosynthetic acclimation of terrestrial and submerged leaves in the amphibious plant Hygrophila difformis.

Horiguchi G, Nemoto K, Yokoyama T, Hirotsu N.

AoB Plants. 2019 Feb 27;11(2):plz009. doi: 10.1093/aobpla/plz009. eCollection 2019 Apr.

6.

How elevated CO2 affects our nutrition in rice, and how we can deal with it.

Ujiie K, Ishimaru K, Hirotsu N, Nagasaka S, Miyakoshi Y, Ota M, Tokida T, Sakai H, Usui Y, Ono K, Kobayashi K, Nakano H, Yoshinaga S, Kashiwagi T, Magoshi J.

PLoS One. 2019 Mar 5;14(3):e0212840. doi: 10.1371/journal.pone.0212840. eCollection 2019.

7.

A network meta-analysis of the efficacy and safety of baloxavir marboxil versus neuraminidase inhibitors for the treatment of influenza in otherwise healthy patients.

Taieb V, Ikeoka H, Ma FF, Borkowska K, Aballéa S, Tone K, Hirotsu N.

Curr Med Res Opin. 2019 Aug;35(8):1355-1364. doi: 10.1080/03007995.2019.1584505. Epub 2019 Apr 1.

PMID:
30810054
8.

Baloxavir marboxil in Japanese patients with seasonal influenza: Dose response and virus type/subtype outcomes from a randomized phase 2 study.

Watanabe A, Ishida T, Hirotsu N, Kawaguchi K, Ishibashi T, Shishido T, Sato C, Portsmouth S, Tsuchiya K, Uehara T.

Antiviral Res. 2019 Mar;163:75-81. doi: 10.1016/j.antiviral.2019.01.012. Epub 2019 Jan 23.

PMID:
30684563
9.

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents.

Hayden FG, Sugaya N, Hirotsu N, Lee N, de Jong MD, Hurt AC, Ishida T, Sekino H, Yamada K, Portsmouth S, Kawaguchi K, Shishido T, Arai M, Tsuchiya K, Uehara T, Watanabe A; Baloxavir Marboxil Investigators Group.

N Engl J Med. 2018 Sep 6;379(10):913-923. doi: 10.1056/NEJMoa1716197.

10.

The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: A prospective, observational study.

Hirotsu N, Saisho Y, Hasegawa T.

Influenza Other Respir Viruses. 2019 Mar;13(2):123-132. doi: 10.1111/irv.12590. Epub 2018 Dec 28.

11.

New insights into the cellular mechanisms of plant growth at elevated atmospheric carbon dioxide concentrations.

Gamage D, Thompson M, Sutherland M, Hirotsu N, Makino A, Seneweera S.

Plant Cell Environ. 2018 Jun;41(6):1233-1246. doi: 10.1111/pce.13206. Review.

PMID:
29611206
12.

Manipulating the Phytic Acid Content of Rice Grain Toward Improving Micronutrient Bioavailability.

Perera I, Seneweera S, Hirotsu N.

Rice (N Y). 2018 Jan 11;11(1):4. doi: 10.1186/s12284-018-0200-y. Review.

13.

Clinical and virologic effects of four neuraminidase inhibitors in influenza A virus-infected children (aged 4-12 years): an open-label, randomized study in Japan.

Hirotsu N, Saisho Y, Hasegawa T, Shishido T.

Expert Rev Anti Infect Ther. 2018 Feb;16(2):173-182. doi: 10.1080/14787210.2018.1421945. Epub 2017 Dec 29.

PMID:
29284320
14.

Partial loss-of-function of NAL1 alters canopy photosynthesis by changing the contribution of upper and lower canopy leaves in rice.

Hirotsu N, Ujiie K, Perera I, Iri A, Kashiwagi T, Ishimaru K.

Sci Rep. 2017 Nov 21;7(1):15958. doi: 10.1038/s41598-017-15886-5.

15.

Effects of Elevated Carbon Dioxide on Photosynthesis and Carbon Partitioning: A Perspective on Root Sugar Sensing and Hormonal Crosstalk.

Thompson M, Gamage D, Hirotsu N, Martin A, Seneweera S.

Front Physiol. 2017 Aug 8;8:578. doi: 10.3389/fphys.2017.00578. eCollection 2017. Review.

16.

Improving Rice Zinc Biofortification Success Rates Through Genetic and Crop Management Approaches in a Changing Environment.

Nakandalage N, Nicolas M, Norton RM, Hirotsu N, Milham PJ, Seneweera S.

Front Plant Sci. 2016 Jun 6;7:764. doi: 10.3389/fpls.2016.00764. eCollection 2016. Review.

17.

N-glycan transition of the early developmental stage in Oryza sativa.

Horiuchi R, Hirotsu N, Miyanishi N.

Biochem Biophys Res Commun. 2016 Aug 26;477(3):426-32. doi: 10.1016/j.bbrc.2016.06.082. Epub 2016 Jun 16.

PMID:
27320861
18.

Comparative analysis of N-glycans in the ungerminated and germinated stages of Oryza sativa.

Horiuchi R, Hirotsu N, Miyanishi N.

Carbohydr Res. 2015 Dec 11;418:1-8. doi: 10.1016/j.carres.2015.09.008. Epub 2015 Oct 8.

PMID:
26513758
19.

[Comparison of the kinetics of granulocytes and lymphocytes between influenza A/H1N1/pdm09 and seasonal influenza A].

Hirotsu N, Hasegawa T, Saisho Y, Murate J, Ikematsu H, Iwaki N, Kawai N, Kashiwagi S.

Kansenshogaku Zasshi. 2014 Jan;88(1):117-25. Japanese.

PMID:
24665588
20.

Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis.

Shinahara W, Takahashi E, Sawabuchi T, Arai M, Hirotsu N, Takasaki Y, Shindo S, Shibao K, Yokoyama T, Nishikawa K, Mino M, Iwaya M, Yamashita Y, Suzuki S, Mizuno D, Kido H.

PLoS One. 2013 Jul 17;8(7):e70060. doi: 10.1371/journal.pone.0070060. Print 2013. Erratum in: PLoS One. 2014;9(7):e104573.

21.

Loss of function of the IAA-glucose hydrolase gene TGW6 enhances rice grain weight and increases yield.

Ishimaru K, Hirotsu N, Madoka Y, Murakami N, Hara N, Onodera H, Kashiwagi T, Ujiie K, Shimizu B, Onishi A, Miyagawa H, Katoh E.

Nat Genet. 2013 Jun;45(6):707-11. doi: 10.1038/ng.2612. Epub 2013 Apr 14.

PMID:
23583977
22.

Increased symptom severity but unchanged neuraminidase inhibitor effectiveness for A(H1N1)pdm09 in the 2010-2011 season: comparison with the previous season and with seasonal A(H3N2) and B.

Kawai N, Ikematsu H, Kawashima T, Maeda T, Ukai H, Hirotsu N, Iwaki N, Kashiwagi S.

Influenza Other Respir Viruses. 2013 May;7(3):448-55. doi: 10.1111/j.1750-2659.2012.00421.x. Epub 2012 Aug 16.

23.

Risk factors of household transmission of pandemic (H1N1) 2009 among patients treated with antivirals: a prospective study at a primary clinic in Japan.

Hirotsu N, Wada K, Oshitani H.

PLoS One. 2012;7(2):e31519. doi: 10.1371/journal.pone.0031519. Epub 2012 Feb 16.

24.

Persistence of pandemic influenza H1N1 virus in young patients after oseltamivir therapy in the 2009-2010 season: a comparison with seasonal H1N1 with or without H275Y mutation.

Kawai N, Ikematsu H, Iwaki N, Kondou K, Hirotsu N, Kawashima T, Maeda T, Tanaka O, Doniwa K, Iwakuni O, Egashira K, Yamaji K, Kashiwagi S.

J Infect Chemother. 2012 Apr;18(2):180-6. doi: 10.1007/s10156-011-0314-2. Epub 2011 Dec 23.

PMID:
22193710
25.

Phase III randomized, double-blind study comparing single-dose intravenous peramivir with oral oseltamivir in patients with seasonal influenza virus infection.

Kohno S, Yen MY, Cheong HJ, Hirotsu N, Ishida T, Kadota J, Mizuguchi M, Kida H, Shimada J; S-021812 Clinical Study Group.

Antimicrob Agents Chemother. 2011 Nov;55(11):5267-76. doi: 10.1128/AAC.00360-11. Epub 2011 Aug 8.

26.

Intravenous peramivir for treatment of influenza A and B virus infection in high-risk patients.

Kohno S, Kida H, Mizuguchi M, Hirotsu N, Ishida T, Kadota J, Shimada J; S-021812 Clinical Study Group.

Antimicrob Agents Chemother. 2011 Jun;55(6):2803-12. doi: 10.1128/AAC.01718-10. Epub 2011 Apr 4.

27.

Comparison of the clinical symptoms and the effectiveness of neuraminidase inhibitors for patients with pandemic influenza H1N1 2009 or seasonal H1N1 influenza in the 2007-2008 and 2008-2009 seasons.

Kawai N, Ikematsu H, Tanaka O, Matsuura S, Maeda T, Yamauchi S, Hirotsu N, Nishimura M, Iwaki N, Kashiwagi S.

J Infect Chemother. 2011 Jun;17(3):375-81. doi: 10.1007/s10156-010-0179-9. Epub 2010 Dec 1.

PMID:
21120678
28.

[How have we understood and responded clinically to pandemic H1N1 2009?].

Hirotsu N, Takahashi A, Hatori Y, Miyakawa K.

Nihon Rinsho. 2010 Sep;68(9):1713-7. Japanese.

PMID:
20845753
29.

Protocol: a simple gel-free method for SNP genotyping using allele-specific primers in rice and other plant species.

Hirotsu N, Murakami N, Kashiwagi T, Ujiie K, Ishimaru K.

Plant Methods. 2010 Apr 21;6:12. doi: 10.1186/1746-4811-6-12.

30.

Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons.

Kawai N, Ikematsu H, Hirotsu N, Maeda T, Kawashima T, Tanaka O, Yamauchi S, Kawamura K, Matsuura S, Nishimura M, Iwaki N, Kashiwagi S.

Clin Infect Dis. 2009 Dec 15;49(12):1828-35. doi: 10.1086/648424.

PMID:
19911968
31.

Clinical effectiveness of oseltamivir for influenza A(H1N1) virus with H274Y neuraminidase mutation.

Kawai N, Ikematsu H, Iwaki N, Kondou K, Hirotsu N, Kawashima T, Maeda T, Tanaka O, Doniwa K, Kashiwagi S.

J Infect. 2009 Sep;59(3):207-12. doi: 10.1016/j.jinf.2009.07.002. Epub 2009 Jul 7.

PMID:
19619898
32.

Comparison of the effectiveness of Zanamivir and Oseltamivir against influenza A/H1N1, A/H3N2, and B.

Kawai N, Ikematsu H, Iwaki N, Maeda T, Kawashima T, Hirotsu N, Kashiwagi S.

Clin Infect Dis. 2009 Apr 1;48(7):996-7. doi: 10.1086/597360. No abstract available.

PMID:
19260819
33.

Evidence for separate translocation pathways in determining cadmium accumulation in grain and aerial plant parts in rice.

Kashiwagi T, Shindoh K, Hirotsu N, Ishimaru K.

BMC Plant Biol. 2009 Jan 21;9:8. doi: 10.1186/1471-2229-9-8.

34.

Improvement of lodging resistance with QTLs for stem diameter in rice (Oryza sativa L.).

Kashiwagi T, Togawa E, Hirotsu N, Ishimaru K.

Theor Appl Genet. 2008 Sep;117(5):749-57. doi: 10.1007/s00122-008-0816-1. Epub 2008 Jun 25.

PMID:
18575836
35.

Time-related identification of chromosome regions affecting plant elongation in rice (Oryza sativa L.).

Hirotsu N, Kashiwagi T, Madoka Y, Ishimaru K.

Plant Physiol Biochem. 2008 Apr;46(4):517-23. doi: 10.1016/j.plaphy.2007.12.002. Epub 2007 Dec 23.

PMID:
18374588
36.

[Detection of respiratory syncytial virus with nested RT-PCR and a new rapid detection test kit in patients with influenza-like illness, including elderly adults].

Kawai N, Ikematsu H, Iwaki N, Kawashima T, Maeda T, Hirotsu N, Nishimura M, Kashiwagi S.

Kansenshogaku Zasshi. 2008 Jan;82(1):1-5. Japanese.

PMID:
18306671
37.

Indian rice "Kasalath" contains genes that improve traits of Japanese premium rice "Koshihikari".

Madoka Y, Kashiwagi T, Hirotsu N, Ishimaru K.

Theor Appl Genet. 2008 Mar;116(5):603-12. Epub 2007 Dec 21.

PMID:
18097643
38.

New target for rice lodging resistance and its effect in a typhoon.

Ishimaru K, Togawa E, Ookawa T, Kashiwagi T, Madoka Y, Hirotsu N.

Planta. 2008 Feb;227(3):601-9. Epub 2007 Oct 25.

PMID:
17960419
39.

A comparison of the effectiveness of zanamivir and oseltamivir for the treatment of influenza A and B.

Kawai N, Ikematsu H, Iwaki N, Maeda T, Kanazawa H, Kawashima T, Tanaka O, Yamauchi S, Kawamura K, Nagai T, Horii S, Hirotsu N, Kashiwagi S.

J Infect. 2008 Jan;56(1):51-7. Epub 2007 Oct 15.

PMID:
17936910
40.

Quantitative trait loci for sucrose, starch, and hexose accumulation before heading in rice.

Ishimaru K, Hirotsu N, Madoka Y, Kashiwagi T.

Plant Physiol Biochem. 2007 Oct-Nov;45(10-11):799-804. Epub 2007 Jul 28.

PMID:
17845859
41.

Longer virus shedding in influenza B than in influenza A among outpatients treated with oseltamivir.

Kawai N, Ikematsu H, Iwaki N, Kawashima T, Maeda T, Mitsuoka S, Kondou K, Satoh I, Miyachi K, Yamaga S, Shigematsu T, Hirotsu N, Kashiwagi S.

J Infect. 2007 Sep;55(3):267-72. Epub 2007 Jul 2.

PMID:
17604839
42.

Zanamivir treatment is equally effective for both influenza A and influenza B.

Kawai N, Ikematsu H, Iwaki N, Tanaka O, Yamanishi Y, Hirotsu N, Kashiwagi S.

Clin Infect Dis. 2007 Jun 15;44(12):1666. No abstract available.

PMID:
17516418
43.

Prevalence of influenza B during the 2004-2005 season in Japan.

Kawai N, Ikematsu H, Iwaki N, Hirotsu N, Kashiwagi S.

Clin Infect Dis. 2006 Nov 1;43(9):1226-8. No abstract available.

PMID:
17029154
44.

A comparison of the effectiveness of oseltamivir for the treatment of influenza A and influenza B: a Japanese multicenter study of the 2003-2004 and 2004-2005 influenza seasons.

Kawai N, Ikematsu H, Iwaki N, Maeda T, Satoh I, Hirotsu N, Kashiwagi S.

Clin Infect Dis. 2006 Aug 15;43(4):439-44. Epub 2006 Jun 26.

PMID:
16838232
45.

Locus prl5 improves lodging resistance of rice by delaying senescence and increasing carbohydrate reaccumulation.

Kashiwagi T, Madoka Y, Hirotsu N, Ishimaru K.

Plant Physiol Biochem. 2006 Feb-Mar;44(2-3):152-7. Epub 2006 Mar 10.

PMID:
16647265
46.

Identification and physiological analyses of a locus for rice yield potential across the genetic background.

Ishimaru K, Kashiwagi T, Hirotsu N, Madoka Y.

J Exp Bot. 2005 Oct;56(420):2745-53. Epub 2005 Aug 30.

PMID:
16131505
47.

The photosynthetic properties of rice leaves treated with low temperature and high irradiance.

Hirotsu N, Makino A, Yokota S, Mae T.

Plant Cell Physiol. 2005 Aug;46(8):1377-83. Epub 2005 Jun 11.

PMID:
15951567
48.

Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season.

Kawai N, Ikematsu H, Iwaki N, Satoh I, Kawashima T, Maeda T, Miyachi K, Hirotsu N, Shigematsu T, Kashiwagi S.

Clin Infect Dis. 2005 May 1;40(9):1309-16. Epub 2005 Mar 16.

PMID:
15825034
49.

[Clinical symptoms of influenza infection in the 2002-2003 season].

Kawai N, Iwaki N, Kawashima T, Satoh I, Shigematsu T, Kondoh K, Maeda T, Kanazawa H, Hirotsu N, Miyachi K, Kunishima O, Ikematsu H, Kashiwagi S.

Kansenshogaku Zasshi. 2004 Aug;78(8):681-9. Japanese.

PMID:
15478643
50.

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