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Acromegaly caused by a somatotroph adenoma in patient with neurofibromatosis type 1.

Hozumi K, Fukuoka H, Odake Y, Takeuchi T, Uehara T, Sato T, Inoshita N, Yoshida K, Matsumoto R, Bando H, Hirota Y, Iguchi G, Taniguchi M, Otsuki N, Nishigori C, Kosaki K, Hasegawa T, Ogawa W, Takahashi Y.

Endocr J. 2019 Jun 12. doi: 10.1507/endocrj.EJ19-0035. [Epub ahead of print]


The association between environmental factors and the development of Crohn's disease with focusing on passive smoking: A multicenter case-control study in Japan.

Kondo K, Ohfuji S, Watanabe K, Yamagami H, Fukushima W, Ito K, Suzuki Y, Hirota Y; Japanese Case-Control Study Group for Crohn's disease.

PLoS One. 2019 Jun 7;14(6):e0216429. doi: 10.1371/journal.pone.0216429. eCollection 2019.


Vulnerable neoatherosclerosis in coronary artery with whole circumference showing intravascular echo attenuation.

Hirota Y, Nomura T, Ono K, Sakaue Y, Ueno D, Hori Y, Yoshioka K, Kikai M, Keira N, Tatsumi T.

Clin Case Rep. 2019 Apr 23;7(5):1094-1097. doi: 10.1002/ccr3.2152. eCollection 2019 May.


Endothelial Cells in the Decidual Bed Are Potential Therapeutic Targets for Preterm Birth Prevention.

Deng W, Yuan J, Cha J, Sun X, Bartos A, Yagita H, Hirota Y, Dey SK.

Cell Rep. 2019 May 7;27(6):1755-1768.e4. doi: 10.1016/j.celrep.2019.04.049.


Contralateral ovarian endometrioma recurrence after unilateral salpingo-oophorectomy.

Hidari T, Hirata T, Arakawa T, Koga K, Neriishi K, Fukuda S, Nakazawa A, Nagashima N, Ma S, Sun H, Takamura M, Harada M, Hirota Y, Wada-Hiraike O, Fujii T, Osuga Y.

BMC Womens Health. 2019 May 2;19(1):59. doi: 10.1186/s12905-019-0760-z.


Glucagon secretions are impaired in patients with fulminant type 1 diabetes.

Komada H, Hirota Y, Ogawa W.

J Diabetes Investig. 2019 May;10(3):866-867. doi: 10.1111/jdi.13041. Epub 2019 Apr 11.


Investigation of the Endoplasmic Reticulum Localization of UDP-Glucuronosyltransferase 2B7 with Systematic Deletion Mutants.

Miyauchi Y, Kimura S, Kimura A, Kurohara K, Hirota Y, Fujimoto K, Mackenzie PI, Tanaka Y, Ishii Y.

Mol Pharmacol. 2019 May;95(5):551-562. doi: 10.1124/mol.118.113902. Epub 2019 Apr 3.


3D 2-layer Elastic Models for Cleft Lip Rhinoplasty Made from 3D Camera.

Ueda K, Hirota Y, Mitsuno D, Okamoto T, Kino H.

Plast Reconstr Surg Glob Open. 2019 Feb 5;7(2):e1917. doi: 10.1097/GOX.0000000000001917. eCollection 2019 Feb. No abstract available.


Acylated anthocyanins derived from purple carrot (Daucus carota L.) induce elevation of blood flow in rat cremaster arteriole.

Tsutsumi A, Horikoshi Y, Fushimi T, Saito A, Koizumi R, Fujii Y, Hu QQ, Hirota Y, Aizawa K, Osakabe N.

Food Funct. 2019 Mar 20;10(3):1726-1735. doi: 10.1039/c8fo02125b.


Association between dietary iron and zinc intake and development of ulcerative colitis: A case-control study in Japan.

Kobayashi Y, Ohfuji S, Kondo K, Fukushima W, Sasaki S, Kamata N, Yamagami H, Fujiwara Y, Suzuki Y, Hirota Y; Japanese Case-Control Study Group for Ulcerative Colitis.

J Gastroenterol Hepatol. 2019 Mar 1. doi: 10.1111/jgh.14642. [Epub ahead of print]


The clinical impact of MRI screening for BRCA mutation carriers: the first report in Japan.

Murakami W, Tozaki M, Nakamura S, Ide Y, Inuzuka M, Hirota Y, Murakami K, Takahama N, Ohgiya Y, Gokan T.

Breast Cancer. 2019 Feb 28. doi: 10.1007/s12282-019-00955-6. [Epub ahead of print]


Usefulness of hemoglobin A1c and glycated albumin measurements for insulinoma screening: an observational case-control study.

Torimoto K, Okada Y, Tanaka Y, Matsuoka A, Hirota Y, Ogawa W, Saisho Y, Kurihara I, Itoh H, Inada S, Koga M.

BMC Cancer. 2019 Feb 26;19(1):174. doi: 10.1186/s12885-019-5389-7.


IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis.

Sun H, Fukuda S, Hirata T, Arakawa T, Ma S, Neriishi K, Wang Y, Takeuchi A, Saeki A, Harada M, Hirota Y, Matsumoto T, Koga K, Wada-Hiraike O, Kurihara M, Fujii T, Osuga Y.

Reprod Sci. 2019 Feb 21:1933719119831782. doi: 10.1177/1933719119831782. [Epub ahead of print]


Preventive effects of pneumococcal and influenza vaccines on community-acquired pneumonia in older individuals in Japan: a case-control study.

Suzuki K, Kondo K, Washio M, Nakashima K, Kan S, Imai S, Yoshimura K, Ota C, Ohfuji S, Fukushima W, Hirota Y.

Hum Vaccin Immunother. 2019 Feb 20:1-7. doi: 10.1080/21645515.2019.1584023. [Epub ahead of print]


PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis.

Arakawa T, Fukuda S, Hirata T, Neriishi K, Wang Y, Takeuchi A, Saeki A, Harada M, Hirota Y, Matsumoto T, Koga K, Wada-Hiraike O, Kurihara M, Fujii T, Osuga Y.

Reprod Sci. 2019 Feb 14:1933719119828095. doi: 10.1177/1933719119828095. [Epub ahead of print]


Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary.

Akino N, Wada-Hiraike O, Isono W, Terao H, Honjo H, Miyamoto Y, Tanikawa M, Sone K, Hirano M, Harada M, Hirata T, Hirota Y, Koga K, Oda K, Fujii T, Osuga Y.

Reprod Biol Endocrinol. 2019 Feb 13;17(1):23. doi: 10.1186/s12958-019-0466-y.


Safety of live attenuated varicella-zoster vaccine in patients with underlying illnesses compared with healthy adults: a prospective cohort study.

Ohfuji S, Ito K, Inoue M, Ishibashi M, Kumashiro H, Hirota Y, Kayano E, Ota N.

BMC Infect Dis. 2019 Jan 28;19(1):95. doi: 10.1186/s12879-019-3719-7.


Effective Application of Mixed Reality Device HoloLens: Simple Manual Alignment of Surgical Field and Holograms.

Mitsuno D, Ueda K, Hirota Y, Ogino M.

Plast Reconstr Surg. 2019 Feb;143(2):647-651. doi: 10.1097/PRS.0000000000005215. Erratum in: Plast Reconstr Surg. 2019 Apr;143(4):1283.


Effects of ipragliflozin on glycemic control, appetite and its related hormones: A prospective, multicenter, open-label study (SOAR-KOBE Study).

Miura H, Sakaguchi K, Okada Y, Yamada T, Otowa-Suematsu N, So A, Komada H, Hirota Y, Ohara T, Kuroki Y, Hara K, Matsuda T, Kishi M, Takeda A, Yokota K, Tamori Y, Ogawa W.

J Diabetes Investig. 2019 Jan 28. doi: 10.1111/jdi.13015. [Epub ahead of print]


Phenotypic differences and similarities of monozygotic twins with maturity-onset diabetes of the young type 5.

Ohara Y, Okada Y, Yamada T, Sugawara K, Kanatani M, Fukuoka H, Hirota Y, Maeda T, Morisada N, Iijima K, Ogawa W.

J Diabetes Investig. 2019 Jan 13. doi: 10.1111/jdi.13004. [Epub ahead of print]


Progesterone governs endometrial proliferation-differentiation switching and blastocyst implantation.

Hirota Y.

Endocr J. 2019 Mar 28;66(3):199-206. doi: 10.1507/endocrj.EJ18-0431. Epub 2019 Jan 8.


Effect of switching from conventional continuous subcutaneous insulin infusion to sensor augmented pump therapy on glycemic profile in Japanese patients with type 1 diabetes.

Matsuoka A, Hirota Y, Urai S, Hamaguchi T, Takeuchi T, Miura H, Suematsu N, So A, Nakamura T, Komada H, Okada Y, Sakaguchi K, Ogawa W.

Diabetol Int. 2018 Jan 22;9(3):201-207. doi: 10.1007/s13340-018-0344-4. eCollection 2018 Jul.


Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis.

Yoshida N, Emoto T, Yamashita T, Watanabe H, Hayashi T, Tabata T, Hoshi N, Hatano N, Ozawa G, Sasaki N, Mizoguchi T, Amin HZ, Hirota Y, Ogawa W, Yamada T, Hirata KI.

Circulation. 2018 Nov 27;138(22):2486-2498. doi: 10.1161/CIRCULATIONAHA.118.033714.


Acute kidney injury due to thin basement membrane disease mimicking Deferasirox nephrotoxicity: a case report.

Oda K, Katayama K, Tanoue A, Murata T, Hirota Y, Mizoguchi S, Hirabayashi Y, Ito T, Ishikawa E, Dohi K, Ito M.

BMC Nephrol. 2018 Dec 17;19(1):363. doi: 10.1186/s12882-018-1180-2.


Functional Temporomandibular Joint Reconstruction in Costochondral Grafting of Micrognathia.

Hirota Y, Ueda K, Katayama M, Otsuki Y.

Plast Reconstr Surg Glob Open. 2018 Oct 2;6(10):e1925. doi: 10.1097/GOX.0000000000001925. eCollection 2018 Oct.


Raman spectroscopy for the diagnosis of unlabeled and unstained histopathological tissue specimens.

Ikeda H, Ito H, Hikita M, Yamaguchi N, Uragami N, Yokoyama N, Hirota Y, Kushima M, Ajioka Y, Inoue H.

World J Gastrointest Oncol. 2018 Nov 15;10(11):439-448. doi: 10.4251/wjgo.v10.i11.439.


Telementoring Demonstration in Craniofacial Surgery With HoloLens, Skype, and Three-Layer Facial Models.

Mitsuno D, Hirota Y, Akamatsu J, Kino H, Okamoto T, Ueda K.

J Craniofac Surg. 2019 Jan;30(1):28-32. doi: 10.1097/SCS.0000000000004899.


Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS.

Azhary JMK, Harada M, Takahashi N, Nose E, Kunitomi C, Koike H, Hirata T, Hirota Y, Koga K, Wada-Hiraike O, Fujii T, Osuga Y.

Endocrinology. 2019 Jan 1;160(1):119-132. doi: 10.1210/en.2018-00675.


Nationwide Survey of Pediatric Inpatients With Hand, Foot, and Mouth Disease, Herpangina, and Associated Complications During an Epidemic Period in Japan: Estimated Number of Hospitalized Patients and Factors Associated With Severe Cases.

Takechi M, Fukushima W, Nakano T, Inui M, Ohfuji S, Kase T, Ito K, Kondo K, Maeda A, Shimizu H, Hirota Y.

J Epidemiol. 2018 Nov 10. doi: 10.2188/jea.JE20180060. [Epub ahead of print]


Thiol-functionalized magnetic carbon nanotubes for magnetic micro-solid phase extraction of sulfonamide antibiotics from milks and commercial chicken meat products.

Nasir ANM, Yahaya N, Zain NNM, Lim V, Kamaruzaman S, Saad B, Nishiyama N, Yoshida N, Hirota Y.

Food Chem. 2019 Mar 15;276:458-466. doi: 10.1016/j.foodchem.2018.10.044. Epub 2018 Oct 11.


Effects of exenatide and liraglutide on postchallenge glucose disposal in individuals with normal glucose tolerance.

Hirota Y, Matsuda T, Nakajima S, Takabe M, Hashimoto N, Nakamura T, Okada Y, Sakaguchi K, Ogawa W.

Endocrine. 2019 Apr;64(1):43-47. doi: 10.1007/s12020-018-1808-9. Epub 2018 Nov 8.


A survey of public attitudes towards third-party reproduction in Japan in 2014.

Yamamoto N, Hirata T, Izumi G, Nakazawa A, Fukuda S, Neriishi K, Arakawa T, Takamura M, Harada M, Hirota Y, Koga K, Wada-Hiraike O, Fujii T, Irahara M, Osuga Y.

PLoS One. 2018 Oct 31;13(10):e0198499. doi: 10.1371/journal.pone.0198499. eCollection 2018.


The prescription rates of glucagon for hypoglycemia by pediatricians and physicians are low in Japan.

Matsumoto M, Awano H, Hirota Y, Nagai M, Bo R, Matsuoka A, Hamaguchi T, Takeuchi T, Nakagawa Y, Ogawa W, Iijima K.

Endocrine. 2019 May;64(2):233-238. doi: 10.1007/s12020-018-1793-z. Epub 2018 Oct 26.


Flexibility of small molecular CD4 mimics as HIV entry inhibitors.

Kobayakawa T, Ohashi N, Hirota Y, Takahashi K, Yamada Y, Narumi T, Yoshimura K, Matsushita S, Harada S, Tamamura H.

Bioorg Med Chem. 2018 Nov 15;26(21):5664-5671. doi: 10.1016/j.bmc.2018.10.011. Epub 2018 Oct 16.


Pharmacology of Parsabiv® (etelcalcetide, ONO-5163/AMG 416), a novel allosteric modulator of the calcium-sensing receptor, for secondary hyperparathyroidism in hemodialysis patients.

Harada K, Fujioka A, Konno M, Inoue A, Yamada H, Hirota Y.

Eur J Pharmacol. 2019 Jan 5;842:139-145. doi: 10.1016/j.ejphar.2018.10.021. Epub 2018 Oct 19.


Effects of Insulin Degludec and Insulin Glargine U300 on Day-to-Day Fasting Plasma Glucose Variability in Individuals with Type 1 Diabetes: A Multicenter, Randomized, Crossover Study (Kobe Best Basal Insulin Study 2).

Miura H, Sakaguchi K, Okada Y, Otowa-Suematsu N, Yamada T, So A, Komada H, Hirota Y, Kishi M, Takeda A, Tominaga Y, Nakamura T, Kuroki Y, Matsuda T, Iida K, Kajikawa M, Ohara T, Yokota K, Hara K, Tateya S, Tamori Y, Ogawa W.

Diabetes Ther. 2018 Dec;9(6):2399-2406. doi: 10.1007/s13300-018-0523-0. Epub 2018 Oct 19.


A case of uterine lymphangioleiomyomatosis in a young woman that was identified via peritonitis.

Yoshizawa H, Kawai S, Hirota Y, Ueda T, Kuroda M, Fujii T.

J Obstet Gynaecol Res. 2019 Feb;45(2):482-486. doi: 10.1111/jog.13822. Epub 2018 Oct 19.


Expression of Nerve Injury-Induced Protein1 (Ninj1) in Endometriosis.

Miyashita M, Koga K, Takeuchi A, Makabe T, Taguchi A, Urata Y, Izumi G, Takamura M, Harada M, Hirata T, Hirota Y, Wada-Hiraike O, Yoshino O, Fujii T, Osuga Y.

Reprod Sci. 2018 Oct 16:1933719118806395. doi: 10.1177/1933719118806395. [Epub ahead of print]


In silico and in vitro analyses of the pathological relevance of the R258H mutation of hepatocyte nuclear factor 4α identified in maturity-onset diabetes of the young type 1.

Sugawara K, Nomura K, Okada Y, Sugano A, Matsumoto M, Takarada T, Takeuchi A, Awano H, Hirota Y, Nishio H, Takaoka Y, Ogawa W.

J Diabetes Investig. 2019 May;10(3):680-684. doi: 10.1111/jdi.12960. Epub 2018 Dec 10.


Cryptococcal Capsules in Cerebrospinal Fluid Visible on Hemocytometer.

Kobayashi Z, Hirota Y, Shintani S.

Can J Neurol Sci. 2018 Nov;45(6):700. doi: 10.1017/cjn.2018.349. Epub 2018 Oct 12. No abstract available.


Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice.

Hirota Y, Nakagawa K, Isomoto K, Sakaki T, Kubodera N, Kamao M, Osakabe N, Suhara Y, Okano T.

PLoS One. 2018 Oct 3;13(10):e0199856. doi: 10.1371/journal.pone.0199856. eCollection 2018.


The efficacy of non-assisted reproductive technology treatment might be limited in infertile patients with advanced endometriosis in their 30s.

Isono W, Wada-Hiraike O, Akino N, Terao H, Harada M, Hirata T, Hirota Y, Koga K, Fujii T, Osuga Y.

J Obstet Gynaecol Res. 2019 Feb;45(2):368-375. doi: 10.1111/jog.13826. Epub 2018 Oct 2.


Mdm2-p53-SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality.

Haraguchi H, Hirota Y, Saito-Fujita T, Tanaka T, Shimizu-Hirota R, Harada M, Akaeda S, Hiraoka T, Matsuo M, Matsumoto L, Hirata T, Koga K, Wada-Hiraike O, Fujii T, Osuga Y.

FASEB J. 2019 Feb;33(2):2610-2620. doi: 10.1096/fj.201801401R. Epub 2018 Sep 27.


Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy.

Nuryadi E, Sasaki Y, Hagiwara Y, Permata TBM, Sato H, Komatsu S, Yoshimoto Y, Murata K, Ando K, Kubo N, Okonogi N, Takakusagi Y, Adachi A, Iwanaga M, Tsuchida K, Tamaki T, Noda SE, Hirota Y, Shibata A, Ohno T, Tokino T, Oike T, Nakano T.

Oncotarget. 2018 Aug 24;9(66):32642-32652. doi: 10.18632/oncotarget.25982. eCollection 2018 Aug 24.


The Effectiveness of Cost Reduction with Charge Displays on Test Ordering under the Health Insurance System in Japan: A Study Using Paper-based Simulated Cases for Residents and Clinical Fellows.

Hirota Y, Suzuki S, Ohira Y, Shikino K, Ikusaka M.

Intern Med. 2019 Jan 15;58(2):187-193. doi: 10.2169/internalmedicine.0738-17. Epub 2018 Sep 12.


Comprehensive Evaluation of Combination Therapy with Basal Insulin and Either Lixisenatide or Vildagliptin in Japanese Patients with Type 2 Diabetes: A Randomized, Open-Label, Parallel-Group, Multicenter Study.

Otowa-Suematsu N, Sakaguchi K, Nakamura T, Hara K, Kishi M, Hashimoto N, Yokota K, Yoshino H, Kuroki Y, Nishiumi T, Sou A, Komada H, Okada Y, Hirota Y, Tamori Y, Ogawa W.

Diabetes Ther. 2018 Oct;9(5):2067-2079. doi: 10.1007/s13300-018-0505-2. Epub 2018 Sep 11.


Impaired glucagon secretion in patients with fulminant type 1 diabetes mellitus.

Komada H, Hirota Y, Sakaguchi K, Okuno Y, Ogawa W, Seino S.

Endocrine. 2019 Mar;63(3):476-479. doi: 10.1007/s12020-018-1750-x. Epub 2018 Sep 10.


3D Separable 2-layered Elastic Models of the Face for Surgical Planning of Local Flaps.

Okamoto T, Hirota Y, Kimura Y, Senda E, Ueda K.

Plast Reconstr Surg Glob Open. 2018 Jul 9;6(7):e1857. doi: 10.1097/GOX.0000000000001857. eCollection 2018 Jul.


Dispersive liquid-liquid microextraction combined with dispersive solid-phase extraction for gas chromatography with mass spectrometry determination of polycyclic aromatic hydrocarbons in aqueous matrices.

Mohd Hassan FW, Muggundha Raoov, Kamaruzaman S, Sanagi MM, Yoshida N, Hirota Y, Nishiyama N, Yahaya N.

J Sep Sci. 2018 Oct;41(19):3751-3763. doi: 10.1002/jssc.201800326. Epub 2018 Sep 9.


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