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Items: 1 to 50 of 835

1.

Beneficial Effect of Pimobendan for Severe Heart Failure Due to Transthyretin Cardiac Amyloidosis.

Okamoto N, Kubo T, Nakashima Y, Ochi Y, Takahashi A, Baba Y, Hirota T, Yamasaki N, Kitaoka H.

Intern Med. 2019 Oct 7. doi: 10.2169/internalmedicine.3675-19. [Epub ahead of print]

2.

Controlling the Circadian Clock with High Temporal Resolution through Photodosing.

Kolarski D, Sugiyama A, Breton G, Rakers C, Ono D, Schulte A, Tama F, Itami K, Szymanski W, Hirota T, Feringa BL.

J Am Chem Soc. 2019 Oct 9;141(40):15784-15791. doi: 10.1021/jacs.9b05445. Epub 2019 Sep 26.

3.

Identification of pathways that regulate circadian rhythms using a larval zebrafish small molecule screen.

Mosser EA, Chiu CN, Tamai TK, Hirota T, Li S, Hui M, Wang A, Singh C, Giovanni A, Kay SA, Prober DA.

Sci Rep. 2019 Aug 27;9(1):12405. doi: 10.1038/s41598-019-48914-7.

4.

Chemical Synthesis of Atomically Tailored SUMO E2 Conjugating Enzymes for the Formation of Covalently Linked SUMO-E2-E3 Ligase Ternary Complexes.

Zhang Y, Hirota T, Kuwata K, Oishi S, Gramani SG, Bode JW.

J Am Chem Soc. 2019 Sep 18;141(37):14742-14751. doi: 10.1021/jacs.9b06820. Epub 2019 Sep 6.

PMID:
31436980
5.

The 2-Year Course of Internet Addiction Among a Japanese Adolescent Psychiatric Clinic Sample with Autism Spectrum Disorder and/or Attention-Deficit Hyperactivity Disorder.

So R, Makino K, Hirota T, Fujiwara M, Ocho K, Ikeda S, Tsubouchi S, Inagakip M.

J Autism Dev Disord. 2019 Nov;49(11):4515-4522. doi: 10.1007/s10803-019-04169-9.

PMID:
31410697
6.

A genetic variant near TSLP is associated with chronic rhinosinusitis with nasal polyps and aspirin-exacerbated respiratory disease in Japanese populations.

Nakayama T, Hirota T, Asaka D, Sakashita M, Ninomiya T, Morikawa T, Okano M, Haruna S, Yoshida N, Takeno S, Tanaka Y, Yoshikawa M, Ishitoya J, Hizawa N, Isogai S, Mitsui C, Taniguchi M, Kojima H, Fujieda S, Tamari M.

Allergol Int. 2019 Jul 17. pii: S1323-8930(19)30102-9. doi: 10.1016/j.alit.2019.06.007. [Epub ahead of print] No abstract available.

7.

Integrated diagnostic approach to wild-type transthyretin cardiac amyloidosis with the use of high-sensitivity cardiac troponin T measurement and 99mTc-pyrophosphate scintigraphy.

Ochi Y, Kubo T, Nakashima Y, Baba Y, Hirota T, Yamasaki N, Yamashita T, Ueda M, Ando Y, Kitaoka H.

J Cardiol. 2019 Jul 16. pii: S0914-5087(19)30150-9. doi: 10.1016/j.jjcc.2019.05.011. [Epub ahead of print]

PMID:
31324572
8.

HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy.

Noguchi E, Akiyama M, Yagami A, Hirota T, Okada Y, Kato Z, Kishikawa R, Fukutomi Y, Hide M, Morita E, Aihara M, Hiragun M, Chinuki Y, Okabe T, Ito A, Adachi A, Fukunaga A, Kubota Y, Aoki T, Aoki Y, Nishioka K, Adachi T, Kanazawa N, Miyazawa H, Sakai H, Kozuka T, Kitamura H, Hashizume H, Kanegane C, Masuda K, Sugiyama K, Tokuda R, Furuta J, Higashimoto I, Kato A, Seishima M, Tajiri A, Tomura A, Taniguchi H, Kojima H, Tanaka H, Sakai A, Morii W, Nakamura M, Kamatani Y, Takahashi A, Kubo M, Tamari M, Saito H, Matsunaga K.

J Allergy Clin Immunol. 2019 Nov;144(5):1354-1363. doi: 10.1016/j.jaci.2019.06.034. Epub 2019 Jul 10.

PMID:
31301374
9.

Reconsideration of the cut-off value of angiotensin-converting enzyme for screening of sarcoidosis in Japanese patients.

Baba Y, Kubo T, Yamanaka S, Ochi Y, Hirota T, Yamasaki N, Ohnishi H, Kubota T, Yokoyama A, Kitaoka H.

J Cardiol. 2019 Dec;74(6):507-511. doi: 10.1016/j.jjcc.2019.05.007. Epub 2019 Jul 10.

PMID:
31300268
10.

Cross-cultural adaptation and psychometric properties of the Social Capital Questionnaire for Adolescent Students among preadolescents and adolescents in Japan.

Hirota T, Adachi M, Takahashi M, Nakamura K.

Psychiatry Clin Neurosci. 2019 Sep;73(9):601-602. doi: 10.1111/pcn.12910. Epub 2019 Jul 15. No abstract available.

PMID:
31271242
11.

Clinical Profile of Thromboembolic Events in Patients With Hypertrophic Cardiomyopathy in a Regional Japanese Cohort - Results From Kochi RYOMA Study.

Hirota T, Kubo T, Baba Y, Ochi Y, Takahashi A, Yamasaki N, Hamashige N, Yamamoto K, Kondo F, Bando K, Yamada E, Furuno T, Yabe T, Doi YL, Kitaoka H.

Circ J. 2019 Jul 25;83(8):1747-1754. doi: 10.1253/circj.CJ-19-0186. Epub 2019 Jun 29.

12.

Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock.

Uehara TN, Mizutani Y, Kuwata K, Hirota T, Sato A, Mizoi J, Takao S, Matsuo H, Suzuki T, Ito S, Saito AN, Nishiwaki-Ohkawa T, Yamaguchi-Shinozaki K, Yoshimura T, Kay SA, Itami K, Kinoshita T, Yamaguchi J, Nakamichi N.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11528-11536. doi: 10.1073/pnas.1903357116. Epub 2019 May 16.

13.

Population Pharmacokinetic Analysis of Phenytoin After Intravenous Administration of Fosphenytoin in Adult and Elderly Epileptic Patients.

Higuchi K, Yamashita D, Kashihara Y, Kakara M, Hirota T, Hirakawa M, Ieiri I.

Ther Drug Monit. 2019 Oct;41(5):674-680. doi: 10.1097/FTD.0000000000000651.

PMID:
31095070
14.

Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy.

Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, Futamura M, Nakamura Y, Ito K.

Asia Pac Allergy. 2019 Apr 22;9(2):e18. doi: 10.5415/apallergy.2019.9.e18. eCollection 2019 Apr.

15.

Folding the genome into mitotic chromosomes.

Takahashi M, Hirota T.

Curr Opin Cell Biol. 2019 Oct;60:19-26. doi: 10.1016/j.ceb.2019.03.005. Epub 2019 Apr 15. Review.

PMID:
30999230
16.

A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts.

Kanazawa J, Kitazawa H, Masuko H, Yatagai Y, Sakamoto T, Kaneko Y, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N.

BMC Med Genet. 2019 Apr 2;20(1):58. doi: 10.1186/s12881-019-0786-y.

17.

Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase.

Nishimura K, Johmura Y, Deguchi K, Jiang Z, Uchida KSK, Suzuki N, Shimada M, Chiba Y, Hirota T, Yoshimura SH, Kono K, Nakanishi M.

Nat Commun. 2019 Feb 28;10(1):981. doi: 10.1038/s41467-019-08957-w.

18.

Enrichment of CLDN18-ARHGAP fusion gene in gastric cancers in young adults.

Nakayama I, Shinozaki E, Sakata S, Yamamoto N, Fujisaki J, Muramatsu Y, Hirota T, Takeuchi K, Takahashi S, Yamaguchi K, Noda T.

Cancer Sci. 2019 Apr;110(4):1352-1363. doi: 10.1111/cas.13967.

19.

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.

Oshima T, Niwa Y, Kuwata K, Srivastava A, Hyoda T, Tsuchiya Y, Kumagai M, Tsuyuguchi M, Tamaru T, Sugiyama A, Ono N, Zolboot N, Aikawa Y, Oishi S, Nonami A, Arai F, Hagihara S, Yamaguchi J, Tama F, Kunisaki Y, Yagita K, Ikeda M, Kinoshita T, Kay SA, Itami K, Hirota T.

Sci Adv. 2019 Jan 23;5(1):eaau9060. doi: 10.1126/sciadv.aau9060. eCollection 2019 Jan.

20.

Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase Iα and δ.

Lee JW, Hirota T, Ono D, Honma S, Honma KI, Park K, Kay SA.

J Med Chem. 2019 Feb 28;62(4):1989-1998. doi: 10.1021/acs.jmedchem.8b01541. Epub 2019 Feb 15.

PMID:
30707835
21.

Improvement of glycemic control by treatment for insomnia with suvorexant in type 2 diabetes mellitus.

Toi N, Inaba M, Kurajoh M, Morioka T, Hayashi N, Hirota T, Miyaoka D, Emoto M, Yamada S.

J Clin Transl Endocrinol. 2018 Dec 18;15:37-44. doi: 10.1016/j.jcte.2018.12.006. eCollection 2019 Mar.

22.

Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.

Qu M, Duffy T, Hirota T, Kay SA.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12305-E12312. doi: 10.1073/pnas.1816411115. Epub 2018 Dec 10.

23.

Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers.

Mori D, Kashihara Y, Yoshikado T, Kimura M, Hirota T, Matsuki S, Maeda K, Irie S, Ieiri I, Sugiyama Y, Kusuhara H.

Drug Metab Pharmacokinet. 2019 Feb;34(1):78-86. doi: 10.1016/j.dmpk.2018.09.003. Epub 2018 Sep 20.

PMID:
30528195
24.

Child and adolescent psychiatry in the Far East: A 5-year follow up on the Consortium on Academic Child and Adolescent Psychiatry in the Far East (CACAP-FE) study.

Hirota T, Guerrero A, Sartorius N, Fung D, Leventhal B, Ong SH, Kaneko H, Apinuntavech S, Bennett A, Bhoomikumar J, Cheon KA, Davaasuren O, Gau S, Hall B, Koren E, van Nguyen T, Oo T, Tan S, Tateno M, Thikeo M, Wiguna T, Wong M, Zheng Y, Skokauskas N.

Psychiatry Clin Neurosci. 2019 Feb;73(2):84-89. doi: 10.1111/pcn.12800. Epub 2018 Dec 24.

PMID:
30471156
25.

Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice.

Sasaki N, Katagiri S, Komazaki R, Watanabe K, Maekawa S, Shiba T, Udagawa S, Takeuchi Y, Ohtsu A, Kohda T, Tohara H, Miyasaka N, Hirota T, Tamari M, Izumi Y.

Front Microbiol. 2018 Oct 24;9:2470. doi: 10.3389/fmicb.2018.02470. eCollection 2018.

26.

Efficacy of DPP-4 inhibitors, GLP-1 analogues, and SGLT2 inhibitors as add-ons to metformin monotherapy in T2DM patients: a model-based meta-analysis.

Inoue H, Tamaki Y, Kashihara Y, Muraki S, Kakara M, Hirota T, Ieiri I.

Br J Clin Pharmacol. 2019 Feb;85(2):393-402. doi: 10.1111/bcp.13807. Epub 2018 Dec 6.

PMID:
30394576
27.

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.

Hirota T, Blakeley P, Sangrithi MN, Mahadevaiah SK, Encheva V, Snijders AP, ElInati E, Ojarikre OA, de Rooij DG, Niakan KK, Turner JMA.

Dev Cell. 2018 Dec 3;47(5):645-659.e6. doi: 10.1016/j.devcel.2018.10.004. Epub 2018 Nov 1.

28.

Ice Ball Crack During CT-Guided Renal Cryoablation Using 1.5-mm-Diameter Cryoprobes.

Ichijo Y, Miura H, Hirota T, Tanaka T, Yoshikawa T, Asai S, Hongo F, Ukimura O, Yamada K.

Cardiovasc Intervent Radiol. 2019 Mar;42(3):475-477. doi: 10.1007/s00270-018-2104-z. Epub 2018 Nov 1.

PMID:
30386882
29.

Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation.

Kashihara Y, Terao Y, Yoda K, Hirota T, Kubota T, Kimura M, Matsuki S, Hirakawa M, Irie S, Ieiri I.

Eur J Clin Pharmacol. 2019 Mar;75(3):351-361. doi: 10.1007/s00228-018-2568-4. Epub 2018 Oct 31.

PMID:
30382297
30.

[Epigenetic Regulation of Pharmacokinetic-related Genes in Human Tissues].

Hirota T.

Yakugaku Zasshi. 2018;138(11):1391-1396. doi: 10.1248/yakushi.18-00145. Review. Japanese.

31.

Characterization of changes in HbA1c in patients with and without secondary failure after metformin treatments by a population pharmacodynamic analysis using mixture models.

Tamaki Y, Maema K, Kakara M, Fukae M, Kinoshita R, Kashihara Y, Muraki S, Hirota T, Ieiri I.

Drug Metab Pharmacokinet. 2018 Dec;33(6):264-269. doi: 10.1016/j.dmpk.2018.08.002. Epub 2018 Aug 16.

PMID:
30360949
32.

Identification of drug transporters contributing to oxaliplatin-induced peripheral neuropathy.

Fujita S, Hirota T, Sakiyama R, Baba M, Ieiri I.

J Neurochem. 2019 Feb;148(3):373-385. doi: 10.1111/jnc.14607. Epub 2018 Dec 3.

PMID:
30295925
33.

Prevalence of pathological and maladaptive Internet use and the association with depression and health-related quality of life in Japanese elementary and junior high school-aged children.

Takahashi M, Adachi M, Nishimura T, Hirota T, Yasuda S, Kuribayashi M, Nakamura K.

Soc Psychiatry Psychiatr Epidemiol. 2018 Dec;53(12):1349-1359. doi: 10.1007/s00127-018-1605-z. Epub 2018 Sep 25.

PMID:
30255383
34.

[GENETIC FACTORS FOR THE DEVELOPMENT OF ALLERGIC DISORDERS].

Tamari M, Hirota T.

Arerugi. 2018;67(8):1006-1010. doi: 10.15036/arerugi.67.1006. Japanese. No abstract available.

PMID:
30249949
35.

Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis.

Iba T, Levy JH, Hirota T, Hiki M, Sato K, Murakami T, Nagaoka I.

Thromb Res. 2018 Nov;171:1-6. doi: 10.1016/j.thromres.2018.09.042. Epub 2018 Sep 6.

PMID:
30216821
36.

Association analyses of eQTLs of the TYRO3 gene and allergic diseases in Japanese populations.

Kanazawa J, Masuko H, Yatagai Y, Sakamoto T, Yamada H, Kitazawa H, Iijima H, Naito T, Saito T, Noguchi E, Hirota T, Tamari M, Hizawa N.

Allergol Int. 2019 Jan;68(1):77-81. doi: 10.1016/j.alit.2018.07.004. Epub 2018 Aug 3.

37.

ATR is a multifunctional regulator of male mouse meiosis.

Widger A, Mahadevaiah SK, Lange J, ElInati E, Zohren J, Hirota T, Pacheco S, Maldonado-Linares A, Stanzione M, Ojarikre O, Maciulyte V, de Rooij DG, Tóth A, Roig I, Keeney S, Turner JMA.

Nat Commun. 2018 Jul 5;9(1):2621. doi: 10.1038/s41467-018-04850-0.

38.

Nucleosome Positioning and Gene Regulation of the SGLT2 Gene in the Renal Proximal Tubular Epithelial Cells.

Takesue H, Hirota T, Tachimura M, Tokashiki A, Ieiri I.

Mol Pharmacol. 2018 Sep;94(3):953-962. doi: 10.1124/mol.118.111807. Epub 2018 Jun 29.

PMID:
29959222
39.

Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer.

Hirota T, Muraki S, Ieiri I.

Clin Pharmacokinet. 2019 Apr;58(4):403-420. doi: 10.1007/s40262-018-0689-7. Review.

PMID:
29915924
40.

Nucleolar integrity during interphase supports faithful Cdk1 activation and mitotic entry.

Hayashi Y, Fujimura A, Kato K, Udagawa R, Hirota T, Kimura K.

Sci Adv. 2018 Jun 6;4(6):eaap7777. doi: 10.1126/sciadv.aap7777. eCollection 2018 Jun.

41.

A systematic review of screening tools in non-young children and adults for autism spectrum disorder.

Hirota T, So R, Kim YS, Leventhal B, Epstein RA.

Res Dev Disabil. 2018 Sep;80:1-12. doi: 10.1016/j.ridd.2018.05.017. Epub 2018 Jun 4.

PMID:
29879612
42.

Intractable Hemophagocytic Syndrome Associated with Systemic Lupus Erythematosus Resistant to Corticosteroids and Intravenous Cyclophosphamide That Was Successfully Treated with Cyclosporine A.

Toko H, Tsuboi H, Umeda N, Honda F, Ohyama A, Takahashi H, Abe S, Yokosawa M, Asashima H, Hagiwara S, Hirota T, Kondo Y, Matsumoto I, Sumida T.

Intern Med. 2018 Sep 15;57(18):2747-2752. doi: 10.2169/internalmedicine.0571-17. Epub 2018 May 18.

43.

Dynamics of sister chromatids through the cell cycle: Together and apart.

Takahashi M, Hirota T.

J Cell Biol. 2018 Jun 4;217(6):1887-1889. doi: 10.1083/jcb.201804091. Epub 2018 May 15.

44.

Quantitative analyses of the metaphase-to-anaphase transition reveal differential kinetic regulation for securin and cyclin B1.

Konishi M, Shindo N, Komiya M, Tanaka K, Itoh T, Hirota T.

Biomed Res. 2018;39(2):75-85. doi: 10.2220/biomedres.39.75.

45.

Positive association of plasma leptin with sleep quality in obese type 2 diabetes patients.

Hirota T, Morioka T, Yoda K, Toi N, Hayashi N, Maruo S, Yamazaki Y, Kurajoh M, Motoyama K, Yamada S, Shoji T, Emoto M, Inaba M.

J Diabetes Investig. 2018 Sep;9(5):1100-1105. doi: 10.1111/jdi.12826. Epub 2018 Mar 26.

46.

Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene.

Takechi T, Hirota T, Sakai T, Maeda N, Kobayashi D, Ieiri I.

Drug Metab Dispos. 2018 May;46(5):628-635. doi: 10.1124/dmd.117.079061. Epub 2018 Feb 2.

PMID:
29437875
47.

Author Correction: Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.

Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T.

Nat Cell Biol. 2018 Apr;20(4):503. doi: 10.1038/s41556-018-0044-0.

PMID:
29434373
48.

Clinical practice guideline for Sjögren's syndrome 2017.

Sumida T, Azuma N, Moriyama M, Takahashi H, Asashima H, Honda F, Abe S, Ono Y, Hirota T, Hirata S, Tanaka Y, Shimizu T, Nakamura H, Kawakami A, Sano H, Ogawa Y, Tsubota K, Ryo K, Saito I, Tanaka A, Nakamura S, Takamura E, Tanaka M, Suzuki K, Takeuchi T, Yamakawa N, Mimori T, Ohta A, Nishiyama S, Yoshihara T, Suzuki Y, Kawano M, Tomiita M, Tsuboi H.

Mod Rheumatol. 2018 May;28(3):383-408. doi: 10.1080/14397595.2018.1438093. Epub 2018 Mar 13. Review.

PMID:
29409370
49.

Vacuolar Protein Degradation via Autophagy Provides Substrates to Amino Acid Catabolic Pathways as an Adaptive Response to Sugar Starvation in Arabidopsis thaliana.

Hirota T, Izumi M, Wada S, Makino A, Ishida H.

Plant Cell Physiol. 2018 Jul 1;59(7):1363-1376. doi: 10.1093/pcp/pcy005.

PMID:
29390157
50.

Protective effect of a newly developed fucose-deficient recombinant antithrombin against histone-induced endothelial damage.

Iba T, Hirota T, Sato K, Nagaoka I.

Int J Hematol. 2018 May;107(5):528-534. doi: 10.1007/s12185-018-2402-x. Epub 2018 Jan 20.

PMID:
29353463

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