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Items: 1 to 50 of 205

1.

Steroid Degradation in Comamonas testosteroni TA441: Identification of the Entire β-Oxidation Cycle of the Cleaved B Ring.

Horinouchi M, Koshino H, Malon M, Hirota H, Hayashi T.

Appl Environ Microbiol. 2019 Oct 1;85(20). pii: e01204-19. doi: 10.1128/AEM.01204-19. Print 2019 Oct 15.

PMID:
31375491
2.

Induction of Nectriapyrone Biosynthesis in the Rice Blast Fungus Pyricularia oryzae by Disturbance of the Two-Component Signal Transduction System.

Motoyama T, Nogawa T, Hayashi T, Hirota H, Osada H.

Chembiochem. 2019 Mar 1;20(5):693-700. doi: 10.1002/cbic.201800620. Epub 2019 Jan 23.

PMID:
30443971
3.

Steroid Degradation in Comamonas testosteroni TA441: Identification of Metabolites and the Genes Involved in the Reactions Necessary before D-Ring Cleavage.

Horinouchi M, Koshino H, Malon M, Hirota H, Hayashi T.

Appl Environ Microbiol. 2018 Oct 30;84(22). pii: e01324-18. doi: 10.1128/AEM.01324-18. Print 2018 Nov 15.

4.

Identification of 4-methyl-5-oxo-octane-1,8-dioic acid and the derivatives as metabolites of steroidal C,D-ring degradation in Comamonas testosteroni TA441.

Horinouchi M, Malon M, Hirota H, Hayashi T.

J Steroid Biochem Mol Biol. 2019 Jan;185:277-286. doi: 10.1016/j.jsbmb.2018.07.008. Epub 2018 Jul 17.

PMID:
30026063
5.

Identification of 9-oxo-1,2,3,4,5,6,10,19-octanor-13,17-secoandrost-8(14)-ene-7,17-dioic acid as a metabolite of steroid degradation in Comamonas testosteroni TA441 and the genes involved in the conversion.

Horinouchi M, Koshino H, Malon M, Hirota H, Hayashi T.

J Steroid Biochem Mol Biol. 2019 Jan;185:268-276. doi: 10.1016/j.jsbmb.2018.07.009. Epub 2018 Jul 17.

PMID:
30026062
6.

Rapid separation of zirconium using microvolume anion-exchange cartridge for 93Zr determination with isotope dilution ICP-MS.

Asai S, Hanzawa Y, Konda M, Suzuki D, Magara M, Kimura T, Ishihara R, Saito K, Yamada S, Hirota H.

Talanta. 2018 Aug 1;185:98-105. doi: 10.1016/j.talanta.2018.03.026. Epub 2018 Mar 14.

PMID:
29759255
7.

Total Synthesis of Highly Oxygenated Bisabolane Sesquiterpene Isolated from Ligularia lankongensis: Relative and Absolute Configurations of the Natural Product.

Kobayashi K, Kunimura R, Takagi H, Hirai M, Kogen H, Hirota H, Kuroda C.

J Org Chem. 2018 Jan 19;83(2):703-715. doi: 10.1021/acs.joc.7b02688. Epub 2018 Jan 8.

PMID:
29282987
8.

Development of SAAP3D force field and the application to replica-exchange Monte Carlo simulation for chignolin and C-peptide.

Iwaoka M, Suzuki T, Shoji Y, Dedachi K, Shimosato T, Minezaki T, Hojo H, Onuki H, Hirota H.

J Comput Aided Mol Des. 2017 Dec;31(12):1039-1052. doi: 10.1007/s10822-017-0084-8. Epub 2017 Nov 17.

PMID:
29147837
9.

The identification of ᴅ-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis.

Kobayashi K, Maezawa T, Tanaka H, Onuki H, Horiguchi Y, Hirota H, Ishida T, Horiike K, Agata Y, Aoki M, Hoshi M, Matsumoto M.

Sci Rep. 2017 Mar 24;7:45175. doi: 10.1038/srep45175.

10.

Estimation of the Compatibility of Blend Composites of Resins by Measuring the Fluorescent Spectra.

Hayashi H, Maeda M, Kuno J, Naruo T, Hirota H, Harada M, Iida K, Onouchi Y, Hirano K.

Anal Sci. 2016;32(11):1251-1256.

11.

Two New Diterpenoids from Salvia przewarskii.

Tsukada H, Kawabe H, Ohtaka A, Saito Y, Okamoto Y, Tori M, Kagechika H, Hirota H, Gong X, Kuroda C, Ohsaki A.

Nat Prod Commun. 2016 Feb;11(2):159-61.

PMID:
27032190
12.

Identification of novel secreted fatty acids that regulate nitrogen catabolite repression in fission yeast.

Sun X, Hirai G, Ueki M, Hirota H, Wang Q, Hongo Y, Nakamura T, Hitora Y, Takahashi H, Sodeoka M, Osada H, Hamamoto M, Yoshida M, Yashiroda Y.

Sci Rep. 2016 Feb 19;6:20856. doi: 10.1038/srep20856.

13.

Preparation of Microvolume Anion-Exchange Cartridge for Inductively Coupled Plasma Mass Spectrometry-Based Determination of (237)Np Content in Spent Nuclear Fuel.

Asai S, Hanzawa Y, Konda M, Suzuki D, Magara M, Kimura T, Ishihara R, Saito K, Yamada S, Hirota H.

Anal Chem. 2016 Mar 15;88(6):3149-55. doi: 10.1021/acs.analchem.5b04330. Epub 2016 Feb 25.

PMID:
26872085
14.

Haenamindole, an unusual diketopiperazine derivative from a marine-derived Penicillium sp. KCB12F005.

Kim JW, Ko SK, Son S, Shin KS, Ryoo IJ, Hong YS, Oh H, Hwang BY, Hirota H, Takahashi S, Kim BY, Osada H, Jang JH, Ahn JS.

Bioorg Med Chem Lett. 2015 Nov 15;25(22):5398-401. doi: 10.1016/j.bmcl.2015.09.026. Epub 2015 Sep 10.

PMID:
26403931
15.

A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis.

Kato N, Nogawa T, Hirota H, Jang JH, Takahashi S, Ahn JS, Osada H.

Biochem Biophys Res Commun. 2015 May 1;460(2):210-5. doi: 10.1016/j.bbrc.2015.03.011. Epub 2015 Mar 11.

PMID:
25770422
17.

Detection of oxygen addition peaks for terpendole E and related indole-diterpene alkaloids in a positive-mode ESI-MS.

Hongo Y, Nakamura T, Takahashi S, Motoyama T, Hayashi T, Hirota H, Osada H, Koshino H.

J Mass Spectrom. 2014 Jun;49(6):537-42. doi: 10.1002/jms.3360.

18.

Infusion of growth hormone into the hippocampus induces molecular and behavioral responses in mice.

Srimontri P, Hirota H, Kanno H, Okada T, Hirabayashi Y, Kato K.

Exp Brain Res. 2014 Sep;232(9):2957-66. doi: 10.1007/s00221-014-3977-y. Epub 2014 May 18. Erratum in: Exp Brain Res. 2014 Nov;232(11):3697.

PMID:
24838553
19.

Identification of 9α-hydroxy-17-oxo-1,2,3,4,10,19-hexanorandrost-6-en-5-oic acid and β-oxidation products of the C-17 side chain in cholic acid degradation by Comamonas testosteroni TA441.

Horinouchi M, Hayashi T, Koshino H, Malon M, Hirota H, Kudo T.

J Steroid Biochem Mol Biol. 2014 Sep;143:306-22. doi: 10.1016/j.jsbmb.2014.04.014. Epub 2014 May 5.

PMID:
24810629
20.

The first isolation of furanoeremophilane from Ligularia nelumbifolia.

Hirota H, Horiguchi Y, Kawaii S, Hanai R, Gong X, Kuroda C.

Nat Prod Commun. 2014 Mar;9(3):325-7.

PMID:
24689207
21.

Terpendole E and its derivative inhibit STLC- and GSK-1-resistant Eg5.

Tarui Y, Chinen T, Nagumo Y, Motoyama T, Hayashi T, Hirota H, Muroi M, Ishii Y, Kondo H, Osada H, Usui T.

Chembiochem. 2014 May 5;15(7):934-8. doi: 10.1002/cbic.201300808. Epub 2014 Mar 19.

PMID:
24648249
22.

Boseongazepines A-C, pyrrolobenzodiazepine derivatives from a Streptomyces sp. 11A057.

Oh M, Jang JH, Choo SJ, Kim SO, Kim JW, Ko SK, Soung NK, Lee JS, Kim CJ, Oh H, Hong YS, Ueki M, Hirota H, Osada H, Kim BY, Ahn JS.

Bioorg Med Chem Lett. 2014 Apr 1;24(7):1802-4. doi: 10.1016/j.bmcl.2014.02.022. Epub 2014 Feb 22.

PMID:
24613164
23.

Application of plug-plug technique to ACE experiments for discovery of peptides binding to a larger target protein: a model study of calmodulin-binding fragments selected from a digested mixture of reduced BSA.

Saito K, Nakato M, Mizuguchi T, Wada S, Uchimura H, Kataoka H, Yokoyama S, Hirota H, Kiso Y.

Electrophoresis. 2014 Mar;35(6):846-54. doi: 10.1002/elps.201300339. Epub 2014 Jan 13.

PMID:
24254403
24.

Anatomical characterization of athetotic and spastic cerebral palsy using an atlas-based analysis.

Yoshida S, Faria AV, Oishi K, Kanda T, Yamori Y, Yoshida N, Hirota H, Iwami M, Okano S, Hsu J, Li X, Jiang H, Li Y, Hayakawa K, Mori S.

J Magn Reson Imaging. 2013 Aug;38(2):288-98. doi: 10.1002/jmri.23931. Epub 2013 Jun 4.

25.

Kidney-protective effects of azelnidipine versus a diuretic in combination with olmesartan in hypertensive patients with diabetes and albuminuria: a randomized study.

Kojima M, Okubo S, Mizubayashi R, Isaka N, Machida H, Okamoto S, Hirota H, Takeuchi M, Kato T, Nakatani K, Mizuno O, Miyagawa K, Makino K, Okura T, Dohi Y, Ito M, Kimura G.

Nephrol Dial Transplant. 2013 Jul;28(7):1802-10. doi: 10.1093/ndt/gft034. Epub 2013 Mar 27.

PMID:
23535223
26.

Terpendole E, a kinesin Eg5 inhibitor, is a key biosynthetic intermediate of indole-diterpenes in the producing fungus Chaunopycnis alba.

Motoyama T, Hayashi T, Hirota H, Ueki M, Osada H.

Chem Biol. 2012 Dec 21;19(12):1611-9. doi: 10.1016/j.chembiol.2012.10.010.

27.

Early behavioural manifestation of Smith-Magenis syndrome (del 17p11.2) in a 4-month-old boy.

Einspieler C, Hirota H, Yuge M, Dejima S, Marschik PB.

Dev Neurorehabil. 2012;15(4):313-6. doi: 10.3109/17518423.2011.654281. Epub 2012 Jun 22.

PMID:
22724898
28.

Possible molecular mechanisms of species recognition by barnacle larvae inferred from multi-specific sequencing analysis of proteinaceous settlement-inducing pheromone.

Yorisue T, Matsumura K, Hirota H, Dohmae N, Kojima S.

Biofouling. 2012;28(6):605-11. doi: 10.1080/08927014.2012.695776.

PMID:
22709314
29.

Four new bisabolane-type sesquiterpenes from Ligularia lankongensis.

Hirota H, Horiguchi Y, Kawaii S, Kuroda C, Hanai R, Gong X.

Nat Prod Commun. 2012 Apr;7(4):451-4.

PMID:
22574439
30.

Chemical and genetic study of Ligularia duciformis and related species in Sichuan and Yunnan Provinces of China.

Nagano H, Hanai R, Yamada H, Matsushima M, Miura Y, Hoya T, Ozawa M, Fujiwara M, Kodama H, Torihata A, Onuki H, Nezu Y, Kawai S, Yamazaki M, Hirota H, Saito Y, Tori M, Ohsaki A, Gong X, Kuroda C.

Chem Biodivers. 2012 Apr;9(4):789-805. doi: 10.1002/cbdv.201100240.

PMID:
22492496
31.

Identification of amino acid residues essential for onion lachrymatory factor synthase activity.

Masamura N, Ohashi W, Tsuge N, Imai S, Ishii-Nakamura A, Hirota H, Nagata T, Kumagai H.

Biosci Biotechnol Biochem. 2012;76(3):447-53.

32.

Athetotic and spastic cerebral palsy: anatomic characterization based on diffusion-tensor imaging.

Yoshida S, Hayakawa K, Oishi K, Mori S, Kanda T, Yamori Y, Yoshida N, Hirota H, Iwami M, Okano S, Matsushita H.

Radiology. 2011 Aug;260(2):511-20. doi: 10.1148/radiol.11101783. Epub 2011 May 9.

PMID:
21555354
33.

Solution structure and fluctuation of the Mg(2+)-bound form of calmodulin C-terminal domain.

Ohashi W, Hirota H, Yamazaki T.

Protein Sci. 2011 Apr;20(4):690-701. doi: 10.1002/pro.598.

34.

Isolation of salsolinol, a tetrahydroisoquinoline alkaloid, from the marine sponge Xestospongia cf. vansoesti as a proteasome inhibitor.

Nagasawa Y, Ueoka R, Yamanokuchi R, Horiuchi N, Ikeda T, Rotinsulu H, Mangindaan RE, Ukai K, Kobayashi H, Namikoshi M, Hirota H, Yokosawa H, Tsukamoto S.

Chem Pharm Bull (Tokyo). 2011;59(2):287-90.

35.

Movements and postures of infants aged 3 to 5 months: to what extent is their optimality related to perinatal events and to the neurological outcome?

Yuge M, Marschik PB, Nakajima Y, Yamori Y, Kanda T, Hirota H, Yoshida N, Einspieler C.

Early Hum Dev. 2011 Mar;87(3):231-7. doi: 10.1016/j.earlhumdev.2010.12.046. Epub 2011 Feb 4.

PMID:
21295927
36.

Notoamide O, a structurally unprecedented prenylated indole alkaloid, and notoamides P-R from a marine-derived fungus, Aspergillus sp.

Tsukamoto S, Umaoka H, Yoshikawa K, Ikeda T, Hirota H.

J Nat Prod. 2010 Aug 27;73(8):1438-40. doi: 10.1021/np1002498. Erratum in: J Nat Prod. 2013 Jun 28;76(6):1232.

PMID:
20795742
37.

Solution structure of polytheonamide B, a highly cytotoxic nonribosomal polypeptide from marine sponge.

Hamada T, Matsunaga S, Fujiwara M, Fujita K, Hirota H, Schmucki R, Güntert P, Fusetani N.

J Am Chem Soc. 2010 Sep 22;132(37):12941-5. doi: 10.1021/ja104616z.

PMID:
20795624
38.

Quantitative diffusion tensor tractography of the motor and sensory tract in children with cerebral palsy.

Yoshida S, Hayakawa K, Yamamoto A, Okano S, Kanda T, Yamori Y, Yoshida N, Hirota H.

Dev Med Child Neurol. 2010 Oct;52(10):935-40. doi: 10.1111/j.1469-8749.2010.03669.x. Epub 2010 Apr 12.

39.

SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene.

Nakaoka Y, Shioyama W, Kunimoto S, Arita Y, Higuchi K, Yamamoto K, Fujio Y, Nishida K, Kuroda T, Hirota H, Yamauchi-Takihara K, Hirano T, Komuro I, Mochizuki N.

J Mol Cell Cardiol. 2010 Aug;49(2):157-64. doi: 10.1016/j.yjmcc.2010.03.001. Epub 2010 Mar 11.

PMID:
20226789
40.

Zinc suppresses Th17 development via inhibition of STAT3 activation.

Kitabayashi C, Fukada T, Kanamoto M, Ohashi W, Hojyo S, Atsumi T, Ueda N, Azuma I, Hirota H, Murakami M, Hirano T.

Int Immunol. 2010 May;22(5):375-86. doi: 10.1093/intimm/dxq017. Epub 2010 Mar 9.

PMID:
20215335
41.

Chemical and genetic differentiation of Ligularia hodgsonii in Japan and China.

Torihata A, Chao X, Kuroda C, Hanai R, Hirota H, Gong X.

Chem Biodivers. 2009 Dec;6(12):2184-91. doi: 10.1002/cbdv.200800346.

PMID:
20020450
42.

A lichen substance as an antiproliferative compound against HL-60 human leukemia cells: 16-O-acetyl-leucotylic acid isolated from Myelochroa aurulenta.

Tokiwano T, Satoh H, Obara T, Hirota H, Yoshizawa Y, Yamamoto Y.

Biosci Biotechnol Biochem. 2009 Nov;73(11):2525-7. Epub 2009 Nov 7.

43.

The effect of sodium dodecyl sulfate and anion-exchange silica gel on matrix-assisted laser desorption/ionization mass spectrometric analysis of proteins.

Asanuma M, Fukuzawa S, Matsuda T, Hirota H.

Rapid Commun Mass Spectrom. 2009 Jun;23(11):1647-53. doi: 10.1002/rcm.4051.

PMID:
19418491
44.

Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp.

Tsukamoto S, Kato H, Greshock TJ, Hirota H, Ohta T, Williams RM.

J Am Chem Soc. 2009 Mar 25;131(11):3834-5. doi: 10.1021/ja810029b. Erratum in: J Am Chem Soc. 2013 Jul 24;135(29):10878.

45.

Isolation of antipodal (-)-versicolamide B and notoamides L-N from a marine-derived Aspergillus sp.

Tsukamoto S, Kawabata T, Kato H, Greshock TJ, Hirota H, Ohta T, Williams RM.

Org Lett. 2009 Mar 19;11(6):1297-300. doi: 10.1021/ol900071c.

46.

Notoamides F-K, prenylated indole alkaloids isolated from a marine-derived Aspergillus sp.

Tsukamoto S, Kato H, Samizo M, Nojiri Y, Onuki H, Hirota H, Ohta T.

J Nat Prod. 2008 Dec;71(12):2064-7. doi: 10.1021/np800471y. Erratum in: J Nat Prod. 2013 Jun 28;76(6):1233.

PMID:
19053517
47.

Symmetrical central tegmental tract (CTT) hyperintense lesions on magnetic resonance imaging in children.

Yoshida S, Hayakawa K, Yamamoto A, Aida N, Okano S, Matsushita H, Kanda T, Yamori Y, Yoshida N, Hirota H.

Eur Radiol. 2009 Feb;19(2):462-9. doi: 10.1007/s00330-008-1167-7. Epub 2008 Sep 16.

PMID:
18795297
48.

Interaction of scaffolding adaptor protein Gab1 with tyrosine phosphatase SHP2 negatively regulates IGF-I-dependent myogenic differentiation via the ERK1/2 signaling pathway.

Koyama T, Nakaoka Y, Fujio Y, Hirota H, Nishida K, Sugiyama S, Okamoto K, Yamauchi-Takihara K, Yoshimura M, Mochizuki S, Hori M, Hirano T, Mochizuki N.

J Biol Chem. 2008 Aug 29;283(35):24234-44. doi: 10.1074/jbc.M803907200. Epub 2008 Jun 23.

49.

Sesquiterpenoids isolated from Eupatorium glehnii. Isolation of guaiaglehnin A, structure revision of Hiyodorilactone B, and genetic comparison.

Tori M, Morishita N, Hirota N, Saito Y, Nakashima K, Sono M, Tanaka M, Utagawa A, Hirota H.

Chem Pharm Bull (Tokyo). 2008 May;56(5):677-81.

50.

Chemical constituents and diversity of Ligularia lankongensis in Yunnan Province of China.

Onuki H, Yamazaki M, Nakamura A, Hanai R, Kuroda C, Gong X, Shen Y, Hirota H.

J Nat Prod. 2008 Apr;71(4):520-4. doi: 10.1021/np070195p. Epub 2008 Feb 9.

PMID:
18260639

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