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Items: 29


Aire Expression Is Inherent to Most Medullary Thymic Epithelial Cells during Their Differentiation Program.

Kawano H, Nishijima H, Morimoto J, Hirota F, Morita R, Mouri Y, Nishioka Y, Matsumoto M.

J Immunol. 2015 Dec 1;195(11):5149-58. doi: 10.4049/jimmunol.1501000. Epub 2015 Oct 26.


Ectopic Aire Expression in the Thymic Cortex Reveals Inherent Properties of Aire as a Tolerogenic Factor within the Medulla.

Nishijima H, Kitano S, Miyachi H, Morimoto J, Kawano H, Hirota F, Morita R, Mouri Y, Masuda K, Imoto I, Ikuta K, Matsumoto M.

J Immunol. 2015 Nov 15;195(10):4641-9. doi: 10.4049/jimmunol.1501026. Epub 2015 Oct 9.


Seasonal and interannual variations in feeding station behavior of cattle: effects of sward and meteorological conditions.

Hirata M, Matsumoto Y, Izumi S, Soga Y, Hirota F, Tobisa M.

Animal. 2015 Apr;9(4):682-90. doi: 10.1017/S1751731114002869. Epub 2014 Dec 2.


NF-κB-inducing kinase in thymic stroma establishes central tolerance by orchestrating cross-talk with not only thymocytes but also dendritic cells.

Mouri Y, Nishijima H, Kawano H, Hirota F, Sakaguchi N, Morimoto J, Matsumoto M.

J Immunol. 2014 Nov 1;193(9):4356-67. doi: 10.4049/jimmunol.1400389. Epub 2014 Sep 26.


Temporal lineage tracing of Aire-expressing cells reveals a requirement for Aire in their maturation program.

Nishikawa Y, Nishijima H, Matsumoto M, Morimoto J, Hirota F, Takahashi S, Luche H, Fehling HJ, Mouri Y, Matsumoto M.

J Immunol. 2014 Mar 15;192(6):2585-92. doi: 10.4049/jimmunol.1302786. Epub 2014 Feb 10.


Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.

Mouri Y, Yano M, Shinzawa M, Shimo Y, Hirota F, Nishikawa Y, Nii T, Kiyonari H, Abe T, Uehara H, Izumi K, Tamada K, Chen L, Penninger JM, Inoue J, Akiyama T, Matsumoto M.

J Immunol. 2011 May 1;186(9):5047-57. doi: 10.4049/jimmunol.1003533. Epub 2011 Mar 25.


Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation.

Nishikawa Y, Hirota F, Yano M, Kitajima H, Miyazaki J, Kawamoto H, Mouri Y, Matsumoto M.

J Exp Med. 2010 May 10;207(5):963-71. doi: 10.1084/jem.20092144. Epub 2010 Apr 19.


Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann DJ, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E.

J Cell Biol. 2009 Aug 10;186(3):393-407. doi: 10.1083/jcb.200904105.


Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology.

Matsumoto M, Zhou Y, Matsuo S, Nakanishi H, Hirose K, Oura H, Arase S, Ishida-Yamamoto A, Bando Y, Izumi K, Kiyonari H, Oshima N, Nakayama R, Matsushima A, Hirota F, Mouri Y, Kuroda N, Sano S, Chaplin DD.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6720-4. doi: 10.1073/pnas.0709345105. Epub 2008 Apr 24.


Developmental stage-dependent collaboration between the TNF receptor-associated factor 6 and lymphotoxin pathways for B cell follicle organization in secondary lymphoid organs.

Qin J, Konno H, Ohshima D, Yanai H, Motegi H, Shimo Y, Hirota F, Matsumoto M, Takaki S, Inoue J, Akiyama T.

J Immunol. 2007 Nov 15;179(10):6799-807.


Visualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals.

Ohtani N, Imamura Y, Yamakoshi K, Hirota F, Nakayama R, Kubo Y, Ishimaru N, Takahashi A, Hirao A, Shimizu T, Mann DJ, Saya H, Hayashi Y, Arase S, Matsumoto M, Kazuki N, Hara E.

Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15034-9. Epub 2007 Sep 11.


Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice.

Niki S, Oshikawa K, Mouri Y, Hirota F, Matsushima A, Yano M, Han H, Bando Y, Izumi K, Matsumoto M, Nakayama KI, Kuroda N, Matsumoto M.

J Clin Invest. 2006 May;116(5):1292-301. Epub 2006 Apr 20.


Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance.

Kinoshita D, Hirota F, Kaisho T, Kasai M, Izumi K, Bando Y, Mouri Y, Matsushima A, Niki S, Han H, Oshikawa K, Kuroda N, Maegawa M, Irahara M, Takeda K, Akira S, Matsumoto M.

J Immunol. 2006 Apr 1;176(7):3995-4002.


Tsutsugamushi disease in Kanagawa Prefecture, Japan: clinical report of two cases and survey of other incidences in 1998.

Ozaki H, Matsuyama T, Hirabayashi K, Iizuka M, Urano K, Kawakubo Y, Kanno S, Ozawa A, Ohkido M, Hirota F, Nagashima N.

Tokai J Exp Clin Med. 2001 Apr;26(1):19-24.


Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice.

Nakagawa T, Tsuchida A, Itakura Y, Nonomura T, Ono M, Hirota F, Inoue T, Nakayama C, Taiji M, Noguchi H.

Diabetes. 2000 Mar;49(3):436-44.


[Effective treatment of AFP-producing lung cancer with UFT].

Hirota F, Hosaka K, Funahashi K, Oota M, Ikeda A, Oobayashi Y, Fujii S, Inada Y, Murai M.

Gan To Kagaku Ryoho. 1999 Feb;26(3):381-4. Japanese.



Furue H, Mugitani H, Hirota F, Suminaga M.

Gan To Kagaku Ryoho. 1988 Apr;15(4 Pt 2-1):797-803. Review. Japanese.


[Interferon production in vitro].

Kaise R, Hirota F, Sakamoto K, Suminaga M, Sato S, Karibe M, Nagai K, Mugitani H, Kako M, Furue H.

Gan To Kagaku Ryoho. 1987 Mar;14(3 Pt 2):896-902. Japanese.


[Host factors in cancer chemotherapy].

Furue H, Kako M, Mugitani H, Fuse K, Kaise R, Hirota F, Takahashi T, Sakamoto K, Takahashi M, Suminaga M, et al.

Gan To Kagaku Ryoho. 1986 Apr;13(4 Pt 2):1126-34. Japanese.


[Simultaneous localization of HBs antigen and alpha-fetoprotein in liver cell dysplasia].

Nagai K, Kako M, Kanazawa S, Hirota F, Takahashi T, Sakamoto K, Suminaga M, Takahashi M, Kaise R, Fuse K, et al.

Nihon Shokakibyo Gakkai Zasshi. 1985 Nov;82(11):2840-4. Japanese. No abstract available.


[Pharmacokinetics of human interferons].

Furue H, Kobayashi H, Komuro T, Kako M, Mugitani H, Fuse K, Kaise R, Nagai K, Takahashi T, Hirota F, et al.

Gan To Kagaku Ryoho. 1984 Apr;11(4):935-42. Japanese.


[Pancreatic oncofetal antigen (POA)].

Mugitani H, Furue H, Kako M, Hirota F, Fuse K, Takahashi T, Sakamoto K, Yamada K, Suminaga M, Ezaki M, Judo R.

Gan To Kagaku Ryoho. 1983 Aug;10(8):1737-43. Japanese.


[Phase II clinical trial of MCNU].

Furue H, Kako M, Mugitani H, Fuse K, Hirota F, Sakamoto K, Takahashi T, Ezaki M, Yamada K, Suminaga M, Kaise R.

Gan To Kagaku Ryoho. 1983 Jul;10(7):1679-83. Japanese.


[Clinical experiences with pepleomycin].

Furue H, Komita T, Mugitani H, Fuse K, Hakozaki M, Kobayashi H, Takahashi T, Hirota F, Yoshihira T.

Gan To Kagaku Ryoho. 1982 May;9(5):930-5. Japanese.


Prism arrangement in human cusp enamel deduced by X-ray diffraction.

Hirota F.

Arch Oral Biol. 1982;27(11):931-7.


[Early detection of complications of myocardial infarct and nursing at sudden changes in clinical conditions].

Got K, Aato K, Hirota F.

Kango Gijutsu. 1979 Apr;25(5):52-60. Japanese. No abstract available.


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