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Items: 1 to 50 of 402

1.

Structure-based virtual screening for novel chymase inhibitors by in silico fragment mapping.

Ozawa SI, Takahashi M, Yamaotsu N, Hirono S.

J Mol Graph Model. 2019 Mar 12;89:102-108. doi: 10.1016/j.jmgm.2019.03.011. [Epub ahead of print]

PMID:
30884446
2.

[Identifying Inhibitors of USP7-HDM2 Protein-Protein Interaction (PPI) by the in silico Fragment-Mapping Method].

Misawa K, Ozawa SI, Yoshida T, Nakagome I, Yamaotsu N, Hirono S.

Yakugaku Zasshi. 2019 Mar 5. doi: 10.1248/yakushi.19-00006. [Epub ahead of print] Japanese.

3.

Low lymphocyte monocyte ratio after neoadjuvant therapy predicts poor survival after pancreatectomy in patients with borderline resectable pancreatic cancer.

Kawai M, Hirono S, Okada KI, Miyazawa M, Shimizu A, Kitahata Y, Kobayashi R, Ueno M, Hayami S, Tanioka K, Yamaue H.

Surgery. 2019 Feb 11. pii: S0039-6060(18)30844-4. doi: 10.1016/j.surg.2018.12.015. [Epub ahead of print]

PMID:
30765142
4.

Concomitant Use of Indocyanine Green Fluorescence Imaging and Interventional Radiology for Detection of Liver Segments During Laparoscopic Anatomical Liver Resection: Pilot Feasibility Study.

Ueno M, Hayami S, Sonomura T, Kawai M, Hirono S, Okada KI, Tanaka R, Yamaue H.

Surg Laparosc Endosc Percutan Tech. 2019 Jan 22. doi: 10.1097/SLE.0000000000000631. [Epub ahead of print]

PMID:
30676538
5.

DFT study of the influence of acetyl groups of cellulose acetate on its intrinsic birefringence and wavelength dependence.

Hayakawa D, Gouda H, Hirono S, Ueda K.

Carbohydr Polym. 2019 Mar 1;207:122-130. doi: 10.1016/j.carbpol.2018.11.074. Epub 2018 Nov 26.

PMID:
30599992
6.

Eighty percent survival rate at 15 years for 1p/19q co-deleted oligodendroglioma treated with upfront chemotherapy irrespective of tumor grade.

Iwadate Y, Matsutani T, Hara A, Hirono S, Ikegami S, Kobayashi M, Ito D, Kawauchi D, Horiguchi K, Tamiya A, Higuchi Y.

J Neurooncol. 2019 Jan;141(1):205-211. doi: 10.1007/s11060-018-03027-5. Epub 2018 Dec 18.

PMID:
30565028
7.

Standardization of surgical procedures for laparoscopic Spiegel lobectomy: A single-institutional experience.

Hayami S, Ueno M, Kawai M, Miyamoto A, Suzaki N, Hirono S, Okada KI, Yamaue H.

Asian J Endosc Surg. 2018 Dec 13. doi: 10.1111/ases.12609. [Epub ahead of print]

PMID:
30549230
8.

2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ Activation.

Morishita K, Shoji Y, Fukui M, Ito Y, Kitao T, Ozawa SI, Hirono S, Shirahase H.

Chem Pharm Bull (Tokyo). 2018;66(12):1131-1152. doi: 10.1248/cpb.c18-00571.

9.

New Model for Predicting Malignancy in Patients With Intraductal Papillary Mucinous Neoplasm.

Shimizu Y, Hijioka S, Hirono S, Kin T, Ohtsuka T, Kanno A, Koshita S, Hanada K, Kitano M, Inoue H, Itoi T, Ueki T, Matsuo K, Yanagisawa A, Yamaue H, Sugiyama M, Okazaki K.

Ann Surg. 2018 Nov 29. doi: 10.1097/SLA.0000000000003108. [Epub ahead of print]

PMID:
30499803
10.

MAPLE-PD trial (Mesenteric Approach vs. Conventional Approach for Pancreatic Cancer during Pancreaticoduodenectomy): study protocol for a multicenter randomized controlled trial of 354 patients with pancreatic ductal adenocarcinoma.

Hirono S, Kawai M, Okada KI, Fujii T, Sho M, Satoi S, Amano R, Eguchi H, Mataki Y, Nakamura M, Matsumoto I, Baba H, Tani M, Kawabata Y, Nagakawa Y, Yamada S, Murakami Y, Shimokawa T, Yamaue H.

Trials. 2018 Nov 8;19(1):613. doi: 10.1186/s13063-018-3002-z.

11.

Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma.

Shigekawa Y, Hayami S, Ueno M, Miyamoto A, Suzaki N, Kawai M, Hirono S, Okada KI, Hamamoto R, Yamaue H.

Oncotarget. 2018 Sep 28;9(76):34320-34335. doi: 10.18632/oncotarget.26144. eCollection 2018 Sep 28.

12.

Design of a New α-1-C-Alkyl-DAB Derivative Acting as a Pharmacological Chaperone for β-Glucocerebrosidase Using Ligand Docking and Molecular Dynamics Simulation.

Nakagome I, Kato A, Yamaotsu N, Yoshida T, Ozawa SI, Adachi I, Hirono S.

Molecules. 2018 Oct 18;23(10). pii: E2683. doi: 10.3390/molecules23102683.

13.

Transition of serum cytokines following pancreaticoduodenectomy: A subsidiary study of JAPAN-PD.

Maeda H, Okada KI, Fujii T, Oba MS, Kawai M, Hirono S, Kodera Y, Sho M, Akahori T, Shimizu Y, Ambo Y, Kondo N, Murakami Y, Ohuchida J, Eguchi H, Nagano H, Sakamoto J, Yamaue H.

Oncol Lett. 2018 Nov;16(5):6847-6853. doi: 10.3892/ol.2018.9422. Epub 2018 Sep 7.

14.

Intensive perioperative rehabilitation improves surgical outcomes after pancreaticoduodenectomy.

Kitahata Y, Hirono S, Kawai M, Okada KI, Miyazawa M, Shimizu A, Kobayashi R, Ueno M, Hayami S, Shimokawa T, Kouda K, Tajima F, Yamaue H.

Langenbecks Arch Surg. 2018 Sep;403(6):711-718. doi: 10.1007/s00423-018-1710-1. Epub 2018 Sep 15.

PMID:
30219924
15.

In silico fragment-mapping method: a new tool for fragment-based/structure-based drug discovery.

Yamaotsu N, Hirono S.

J Comput Aided Mol Des. 2018 Nov;32(11):1229-1245. doi: 10.1007/s10822-018-0160-8. Epub 2018 Sep 8.

PMID:
30196523
16.

Identification of a novel HLA-A24-restricted cytotoxic T lymphocyte epitope peptide derived from mesothelin in pancreatic cancer.

Tsukagoshi M, Wada S, Hirono S, Yoshida S, Yada E, Sasada T, Shirabe K, Kuwano H, Yamaue H.

Oncotarget. 2018 Jul 31;9(59):31448-31458. doi: 10.18632/oncotarget.25837. eCollection 2018 Jul 31.

17.

Detection of needle tract implantation and peritoneal seeding after radiofrequency ablation using intraoperative near-infrared fluorescence system for recurrent hepatocellular carcinoma: a case report.

Nakamura M, Hayami S, Ueno M, Kawai M, Miyamoto A, Suzaki N, Hirono S, Okada KI, Miyazawa M, Kitahata Y, Yamaue H.

Surg Case Rep. 2018 Jul 13;4(1):76. doi: 10.1186/s40792-018-0485-5.

18.

Real-time methylation-specific PCR for the evaluation of methylation status of MGMT gene in glioblastoma.

Yoshioka M, Matsutani T, Hara A, Hirono S, Hiwasa T, Takiguchi M, Iwadate Y.

Oncotarget. 2018 Jun 12;9(45):27728-27735. doi: 10.18632/oncotarget.25543. eCollection 2018 Jun 12.

19.

Ischemic gastropathy after distal pancreatectomy with en bloc celiac axis resection for pancreatic body cancer.

Okada KI, Kawai M, Hirono S, Miyazawa M, Kitahata Y, Ueno M, Hayami S, Shimokawa T, Yamaue H.

Langenbecks Arch Surg. 2018 Aug;403(5):561-571. doi: 10.1007/s00423-018-1692-z. Epub 2018 Jun 28.

PMID:
29956031
20.

Hammock Middle Cerebral Artery and Delayed Infarction in Lenticulostriate Artery After Staged Resection of Giant Insular Glioma.

Hirono S, Ozaki K, Ito D, Matsutani T, Iwadate Y.

World Neurosurg. 2018 Sep;117:80-83. doi: 10.1016/j.wneu.2018.05.226. Epub 2018 Jun 7.

PMID:
29886303
21.

Clinical impact of developing better practices at the institutional level on surgical outcomes after distal pancreatectomy in 1515 patients: Domestic audit of the Japanese Society of Pancreatic Surgery.

Satoi S, Yamamoto T, Motoi F, Matsumoto I, Yoshitomi H, Amano R, Tahara M, Murakami Y, Arimitsu H, Hirono S, Sho M, Ryota H, Ohtsuka M, Unno M, Takeyama Y, Yamaue H.

Ann Gastroenterol Surg. 2018 Mar 25;2(3):212-219. doi: 10.1002/ags3.12066. eCollection 2018 May.

22.

Mesenteric approach during pancreaticoduodenectomy for pancreatic ductal adenocarcinoma.

Hirono S, Kawai M, Okada KI, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Shimokawa T, Nakao A, Yamaue H.

Ann Gastroenterol Surg. 2017 Jun 7;1(3):208-218. doi: 10.1002/ags3.12013. eCollection 2017 Sep.

23.

Modified Blumgart Mattress Suture Versus Conventional Interrupted Suture in Pancreaticojejunostomy During Pancreaticoduodenectomy: Randomized Controlled Trial.

Hirono S, Kawai M, Okada KI, Miyazawa M, Kitahata Y, Hayami S, Ueno M, Yamaue H.

Ann Surg. 2019 Feb;269(2):243-251. doi: 10.1097/SLA.0000000000002802.

25.

Validation of molecular force field parameters for peptides including isomerized amino acids.

Oda A, Nakayoshi T, Fukuyoshi S, Kurimoto E, Yamaotsu N, Hirono S, Takahashi O.

Chirality. 2018 Apr;30(4):332-341. doi: 10.1002/chir.22821. Epub 2018 Feb 2.

PMID:
29393985
26.

Prospective validation of patient fatigue questionnaire (FACIT-F) for fatigue assessment in nab-paclitaxel plus gemcitabine therapy.

Okada KI, Hirono S, Kawai M, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Hayami S, Shimokawa T, Yamaue H.

Mol Clin Oncol. 2018 Jan;8(1):121-126. doi: 10.3892/mco.2017.1485. Epub 2017 Nov 3.

27.

Efficacy and safety of sofosbuvir and ledipasvir in Japanese patients aged 75 years or over with hepatitis C genotype 1.

Ozono Y, Nagata K, Hasuike S, Iwakiri H, Nakamura K, Tsuchimochi M, Yamada Y, Takaishi Y, Sueta M, Miike T, Tahara Y, Yamamoto S, Shide K, Hidaka T, Kubuki Y, Kusumoto K, Ochiai T, Kato J, Komada N, Hirono S, Kuroki K, Shigehira M, Shimoda K.

World J Hepatol. 2017 Dec 28;9(36):1340-1345. doi: 10.4254/wjh.v9.i36.1340.

28.

Percutaneous Coronary Intervention for a Patient with Left Main Coronary Compression Syndrome.

Ikegami R, Ozaki K, Ozawa T, Hirono S, Ito M, Minamino T.

Intern Med. 2018 May 15;57(10):1421-1424. doi: 10.2169/internalmedicine.9534-17. Epub 2018 Jan 11. Review.

29.

Dual Antiplatelet Therapy Guided by CYP2C19 Polymorphisms after Implantation of Second-Generation Drug-Eluting Stents for Management of Acute Coronary Syndrome.

Ozawa T, Suda M, Ikegami R, Takano T, Wakasugi T, Yanagawa T, Tanaka K, Ozaki K, Hirono S, Minamino T.

Int Heart J. 2018 Jan 27;59(1):21-26. doi: 10.1536/ihj.17-005. Epub 2017 Dec 27.

30.

Exploration of DPP-IV inhibitors with a novel scaffold by multistep in silico screening.

Uchida T, Wakasugi M, Kitamura T, Yamamoto T, Asakura M, Fujiwara R, Itoh T, Fujii H, Hirono S.

J Mol Graph Model. 2018 Jan;79:254-263. doi: 10.1016/j.jmgm.2017.12.005. Epub 2017 Dec 14.

PMID:
29274572
31.

Indocyanine green fluorescence imaging techniques and interventional radiology during laparoscopic anatomical liver resection (with video).

Ueno M, Hayami S, Sonomura T, Tanaka R, Kawai M, Hirono S, Okada KI, Yamaue H.

Surg Endosc. 2018 Feb;32(2):1051-1055. doi: 10.1007/s00464-017-5997-8. Epub 2017 Dec 22.

PMID:
29273869
32.

Aortic Regurgitation Presenting with Recurrent Detachment of a Prosthetic Valve, as the First Presenting Symptom of Cardiovascular Behçet's Disease.

Takayama T, Ozawa T, Sanada A, Watanabe T, Ito M, Hirono S, Aizawa Y, Minamino T.

Intern Med. 2018 Mar 15;57(6):823-827. doi: 10.2169/internalmedicine.9603-17. Epub 2017 Dec 8. Review.

33.

Novel Non-carboxylate Benzoylsulfonamide-Based Protein Tyrosine Phosphatase 1B Inhibitors with Non-competitive Actions.

Morishita K, Shoji Y, Tanaka S, Fukui M, Ito Y, Kitao T, Ozawa SI, Hirono S, Shirahase H.

Chem Pharm Bull (Tokyo). 2017;65(12):1144-1160. doi: 10.1248/cpb.c17-00635.

34.

Reinforced staplers for distal pancreatectomy.

Kawai M, Hirono S, Okada KI, Satoi S, Yanagimoto H, Kon M, Murakami Y, Kondo N, Sho M, Akahori T, Toyama H, Fukumoto T, Fujii T, Matsumoto I, Eguchi H, Ikoma H, Takeda Y, Fujimoto J, Yamaue H.

Langenbecks Arch Surg. 2017 Dec;402(8):1197-1204. doi: 10.1007/s00423-017-1634-1. Epub 2017 Nov 4.

PMID:
29103084
35.

Left Gastric Artery Reconstruction after Distal Pancreatectomy with Celiac Axis En-Bloc Resection: How We Do It.

Okada KI, Hirono S, Kawai M, Hayami S, Asamura S, Wada Y, Ueno M, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H.

Gastrointest Tumors. 2017 Sep;4(1-2):28-35. doi: 10.1159/000469660. Epub 2017 Apr 12.

36.

[II.Portal Vein Resection during Pancreaticoduodenectomy].

Hirono S, Yamaue H.

Gan To Kagaku Ryoho. 2017 Oct;44(10):845-848. Japanese. No abstract available.

PMID:
29066677
37.

Postoperative Visceral Tissue Edema Assessed by Computed Tomography Is a Predictor for Severe Complications After Pancreaticoduodenectomy.

Shimizu A, Kawai M, Hirono S, Okada KI, Miyazawa M, Kitahata Y, Ueno M, Hayami S, Miyamoto A, Kimoto Y, Shimokawa T, Yamaue H.

J Gastrointest Surg. 2018 Jan;22(1):77-87. doi: 10.1007/s11605-017-3608-6. Epub 2017 Oct 18.

PMID:
29047069
39.

In silico analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease.

Kato A, Nakagome I, Nakagawa S, Kinami K, Adachi I, Jenkinson SF, Désiré J, Blériot Y, Nash RJ, Fleet GWJ, Hirono S.

Org Biomol Chem. 2017 Nov 15;15(44):9297-9304. doi: 10.1039/c7ob02281f.

PMID:
28959811
40.

Natural history of de novo High Grade Glioma: first description of growth parabola.

Altieri R, Hirono S, Duffau H, Ducati A, Fontanella M, LA Rocca G, Melcarne A, Panciani PP, Spena G, Garbossa D.

J Neurosurg Sci. 2017 Jul 26. doi: 10.23736/S0390-5616.17.04067-X. [Epub ahead of print]

PMID:
28748908
41.

Effect of Neoadjuvant Nab-Paclitaxel plus Gemcitabine Therapy on Overall Survival in Patients with Borderline Resectable Pancreatic Cancer: A Prospective Multicenter Phase II Trial (NAC-GA Trial).

Okada KI, Shimokawa T, Hirono S, Kawai M, Sho M, Satoi S, Matsumoto I, Eguchi H, Murakami Y, Yamada S, Doi M, Yamaue H; NAC-GA investigators.

Oncology. 2017;93(5):343-346. doi: 10.1159/000478660. Epub 2017 Jul 19.

PMID:
28719890
42.

In silico analyses of the effects of a point mutation and a pharmacological chaperone on the thermal fluctuation of phenylalanine hydroxylase.

Hayakawa D, Yamaotsu N, Nakagome I, Ozawa SI, Yoshida T, Hirono S.

Biophys Chem. 2017 Sep;228:47-54. doi: 10.1016/j.bpc.2017.06.014. Epub 2017 Jun 30.

PMID:
28697448
43.

Successful removal of an internal pancreatic stent that migrated into the bile duct using double-balloon enteroscopy after pancreaticoduodenectomy.

Hirono S, Kawai M, Yamashita Y, Okada KI, Miyazawa M, Ueno M, Maeda Y, Itonaga M, Kitano M, Yamaue H.

Surg Today. 2018 Feb;48(2):167-174. doi: 10.1007/s00595-017-1563-1. Epub 2017 Jul 8.

PMID:
28689268
44.

Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin.

Yamasaki K, Hyodo S, Taguchi K, Nishi K, Yamaotsu N, Hirono S, Chuang VTG, Seo H, Maruyama T, Otagiri M.

PLoS One. 2017 Jun 29;12(6):e0180404. doi: 10.1371/journal.pone.0180404. eCollection 2017.

45.

A novel serine racemase inhibitor suppresses neuronal over-activation in vivo.

Mori H, Wada R, Takahara S, Horino Y, Izumi H, Ishimoto T, Yoshida T, Mizuguchi M, Obita T, Gouda H, Hirono S, Toyooka N.

Bioorg Med Chem. 2017 Jul 15;25(14):3736-3745. doi: 10.1016/j.bmc.2017.05.011. Epub 2017 May 11.

PMID:
28533113
46.

Investigation of substrate recognition for cytochrome P450 1A2 mediated by water molecules using docking and molecular dynamics simulations.

Watanabe Y, Fukuyoshi S, Kato K, Hiratsuka M, Yamaotsu N, Hirono S, Gouda H, Oda A.

J Mol Graph Model. 2017 Jun;74:326-336. doi: 10.1016/j.jmgm.2017.04.006. Epub 2017 Apr 13.

PMID:
28475969
47.

Precise prediction of activators for the human constitutive androstane receptor using structure-based three-dimensional quantitative structure-activity relationship methods.

Kato H, Yamaotsu N, Iwazaki N, Okamura S, Kume T, Hirono S.

Drug Metab Pharmacokinet. 2017 Jun;32(3):179-188. doi: 10.1016/j.dmpk.2017.02.001. Epub 2017 Feb 9.

PMID:
28412023
48.

Current advance and future foresight of surgical treatment for pancreatic cancer.

Hirono S, Yamaue H.

Nihon Shokakibyo Gakkai Zasshi. 2017;114(4):607-616. doi: 10.11405/nisshoshi.114.607. Review. Japanese. No abstract available.

PMID:
28381777
49.

Phase I Study of Nab-Paclitaxel plus Gemcitabine as Neoadjuvant Therapy for Borderline Resectable Pancreatic Cancer.

Okada KI, Hirono S, Kawai M, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Hayami S, Yamaue H.

Anticancer Res. 2017 Feb;37(2):853-858.

PMID:
28179342
50.

The Pluripotent Stem-Cell Marker Alkaline Phosphatase is Highly Expressed in Refractory Glioblastoma with DNA Hypomethylation.

Iwadate Y, Suganami A, Tamura Y, Matsutani T, Hirono S, Shinozaki N, Hiwasa T, Takiguchi M, Saeki N.

Neurosurgery. 2017 Feb 1;80(2):248-256. doi: 10.1093/neuros/nyw026.

PMID:
28173571

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