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Items: 1 to 50 of 418

1.

Hierarchical organization of cortical and thalamic connectivity.

Harris JA, Mihalas S, Hirokawa KE, Whitesell JD, Choi H, Bernard A, Bohn P, Caldejon S, Casal L, Cho A, Feiner A, Feng D, Gaudreault N, Gerfen CR, Graddis N, Groblewski PA, Henry AM, Ho A, Howard R, Knox JE, Kuan L, Kuang X, Lecoq J, Lesnar P, Li Y, Luviano J, McConoughey S, Mortrud MT, Naeemi M, Ng L, Oh SW, Ouellette B, Shen E, Sorensen SA, Wakeman W, Wang Q, Wang Y, Williford A, Phillips JW, Jones AR, Koch C, Zeng H.

Nature. 2019 Nov;575(7781):195-202. doi: 10.1038/s41586-019-1716-z. Epub 2019 Oct 30.

PMID:
31666704
2.

Three-dimensional surface models of autopsied human brains constructed from multiple photographs by photogrammetry.

Shintaku H, Yamaguchi M, Toru S, Kitagawa M, Hirokawa K, Yokota T, Uchihara T.

PLoS One. 2019 Jul 10;14(7):e0219619. doi: 10.1371/journal.pone.0219619. eCollection 2019.

3.

How to demix Alzheimer-type and PSP-type tau lesions out of their mixture -hybrid approach to dissect comorbidity.

Ebashi M, Ito Y, Uematsu M, Nakamura A, Hirokawa K, Kamei S, Uchihara T.

Acta Neuropathol Commun. 2019 May 6;7(1):71. doi: 10.1186/s40478-019-0708-4.

4.

Detection of AD-specific four repeat tau with deamidated asparagine residue 279-specific fraction purified from 4R tau polyclonal antibody.

Ebashi M, Toru S, Nakamura A, Kamei S, Yokota T, Hirokawa K, Uchihara T.

Acta Neuropathol. 2019 Jul;138(1):163-166. doi: 10.1007/s00401-019-02012-0. Epub 2019 Apr 20. No abstract available.

5.

Adjustment ability and associated factors of outpatients living with cancer.

Hirokawa K, Suzuki S.

Nurs Open. 2018 Dec 14;6(2):408-417. doi: 10.1002/nop2.221. eCollection 2019 Apr.

6.

Effects of chocolate containing Leuconostoc mesenteroides strain NTM048 on immune function: a randomized, double-blind, placebo-controlled trial.

Kuroda R, Higuchi H, Yoshida K, Yonejima Y, Hisa K, Utsuyama M, Osawa K, Hirokawa K.

Immun Ageing. 2018 Nov 20;15:29. doi: 10.1186/s12979-018-0139-2. eCollection 2018.

7.

Shared and distinct transcriptomic cell types across neocortical areas.

Tasic B, Yao Z, Graybuck LT, Smith KA, Nguyen TN, Bertagnolli D, Goldy J, Garren E, Economo MN, Viswanathan S, Penn O, Bakken T, Menon V, Miller J, Fong O, Hirokawa KE, Lathia K, Rimorin C, Tieu M, Larsen R, Casper T, Barkan E, Kroll M, Parry S, Shapovalova NV, Hirschstein D, Pendergraft J, Sullivan HA, Kim TK, Szafer A, Dee N, Groblewski P, Wickersham I, Cetin A, Harris JA, Levi BP, Sunkin SM, Madisen L, Daigle TL, Looger L, Bernard A, Phillips J, Lein E, Hawrylycz M, Svoboda K, Jones AR, Koch C, Zeng H.

Nature. 2018 Nov;563(7729):72-78. doi: 10.1038/s41586-018-0654-5. Epub 2018 Oct 31.

8.

Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer's disease.

Whitesell JD, Buckley AR, Knox JE, Kuan L, Graddis N, Pelos A, Mukora A, Wakeman W, Bohn P, Ho A, Hirokawa KE, Harris JA.

J Comp Neurol. 2019 Sep 1;527(13):2122-2145. doi: 10.1002/cne.24555. Epub 2018 Dec 4.

PMID:
30311654
9.

Relationship between the Second to Fourth Finger Length Ratio and Calcaneus Quantitative Ultrasound.

Takahata Y, Hirokawa K.

Sci Rep. 2018 Oct 2;8(1):14603. doi: 10.1038/s41598-018-33056-z.

10.

Associations between broader autism phenotype (BAP) and maternal attachment are moderated by maternal postpartum depression when infants are one month old: A prospective study of the Japan environment & children's study.

Hirokawa K, Kimura T, Ikehara S, Honjo K, Sato T, Ueda K, Iso H; Japan Environment & Children's Study Group.

J Affect Disord. 2019 Jan 15;243:485-493. doi: 10.1016/j.jad.2018.09.060. Epub 2018 Sep 19.

PMID:
30273887
11.

Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer's Disease?

Fulop T, Witkowski JM, Bourgade K, Khalil A, Zerif E, Larbi A, Hirokawa K, Pawelec G, Bocti C, Lacombe G, Dupuis G, Frost EH.

Front Aging Neurosci. 2018 Jul 24;10:224. doi: 10.3389/fnagi.2018.00224. eCollection 2018. Review.

12.

Development of an adjustment ability scale for outpatients with cancer: Verification of its reliability and validity.

Hirokawa K, Suzuki S.

Nurs Open. 2018 Apr 15;5(3):351-361. doi: 10.1002/nop2.145. eCollection 2018 Jul.

13.

A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality.

Daigle TL, Madisen L, Hage TA, Valley MT, Knoblich U, Larsen RS, Takeno MM, Huang L, Gu H, Larsen R, Mills M, Bosma-Moody A, Siverts LA, Walker M, Graybuck LT, Yao Z, Fong O, Nguyen TN, Garren E, Lenz GH, Chavarha M, Pendergraft J, Harrington J, Hirokawa KE, Harris JA, Nicovich PR, McGraw MJ, Ollerenshaw DR, Smith KA, Baker CA, Ting JT, Sunkin SM, Lecoq J, Lin MZ, Boyden ES, Murphy GJ, da Costa NM, Waters J, Li L, Tasic B, Zeng H.

Cell. 2018 Jul 12;174(2):465-480.e22. doi: 10.1016/j.cell.2018.06.035.

14.

Macroscopic Localized Subicular Thinning as a Potential Indicator of Amyotrophic Lateral Sclerosis.

Yamada H, Takeda T, Uchihara T, Sato S, Kirimura S, Hirota Y, Kodama M, Kitagawa M, Hirokawa K, Yokota T, Toru S.

Eur Neurol. 2018;79(3-4):200-205. doi: 10.1159/000487992. Epub 2018 Mar 23.

PMID:
29587294
15.

14-3-3 protein sigma isoform co-localizes with phosphorylated α-synuclein in Lewy bodies and Lewy neurites in patients with Lewy body disease.

Wakabayashi K, Umahara T, Hirokawa K, Hanyu H, Uchihara T.

Neurosci Lett. 2018 May 1;674:171-175. doi: 10.1016/j.neulet.2018.03.013. Epub 2018 Mar 16.

PMID:
29555518
16.

[A Case of Gallbladder Carcinoma Producing Alpha-Fetoprotein(AFP)with Metastatic Liver Tumor].

Takahashi H, Suzuki Y, Higuchi K, Yoshinouchi S, Enomoto N, Yoshida T, Ohno R, Mutoh M, Hirokawa K.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1182-1184. Japanese.

PMID:
29394574
17.

Brainstem tau pathology in Alzheimer's disease is characterized by increase of three repeat tau and independent of amyloid β.

Uematsu M, Nakamura A, Ebashi M, Hirokawa K, Takahashi R, Uchihara T.

Acta Neuropathol Commun. 2018 Jan 3;6(1):1. doi: 10.1186/s40478-017-0501-1.

18.

Association Between Cortisol to DHEA-s Ratio and Sickness Absence in Japanese Male Workers.

Hirokawa K, Fujii Y, Taniguchi T, Takaki J, Tsutsumi A.

Int J Behav Med. 2018 Jun;25(3):362-367. doi: 10.1007/s12529-017-9700-1.

PMID:
29164484
19.

Time-dependent and lesion-dependent HMGB1-selective localization in brains of patients with cerebrovascular diseases.

Umahara T, Uchihara T, Hirokawa K, Hirao K, Shimizu S, Hashimoto T, Terasi H, Hanyu H.

Histol Histopathol. 2018 Feb;33(2):215-222. doi: 10.14670/HH-11-914. Epub 2017 Jul 3.

PMID:
28671243
20.

Three-Repeat Tau with Grain-Like Structures and Distribution in an 83-Year-Old Man.

Kasahata N, Sato T, Onishi I, Kitagawa M, Uchihara T, Hirokawa K.

J Alzheimers Dis. 2017;58(3):681-685. doi: 10.3233/JAD-160672.

PMID:
28453470
21.

Diverse Central Projection Patterns of Retinal Ganglion Cells.

Martersteck EM, Hirokawa KE, Evarts M, Bernard A, Duan X, Li Y, Ng L, Oh SW, Ouellette B, Royall JJ, Stoecklin M, Wang Q, Zeng H, Sanes JR, Harris JA.

Cell Rep. 2017 Feb 21;18(8):2058-2072. doi: 10.1016/j.celrep.2017.01.075.

22.

Occupational status and job stress in relation to cardiovascular stress reactivity in Japanese workers.

Hirokawa K, Ohira T, Nagayoshi M, Kajiura M, Imano H, Kitamura A, Kiyama M, Okada T, Iso H.

Prev Med Rep. 2016 May 19;4:61-7. doi: 10.1016/j.pmedr.2016.05.010. eCollection 2016 Dec.

23.

Dehydroepiandrosterone-sulfate is associated with cardiovascular reactivity to stress in women.

Hirokawa K, Ohira T, Nagayoshi M, Kajiura M, Imano H, Kitamura A, Kiyama M, Okada T, Iso H.

Psychoneuroendocrinology. 2016 Jul;69:116-22. doi: 10.1016/j.psyneuen.2016.04.005. Epub 2016 Apr 8.

PMID:
27104812
24.

Immunomodulation in Middle-Aged Humans Via the Ingestion of Physta® Standardized Root Water Extract of Eurycoma longifolia Jack--A Randomized, Double-Blind, Placebo-Controlled, Parallel Study.

George A, Suzuki N, Abas AB, Mohri K, Utsuyama M, Hirokawa K, Takara T.

Phytother Res. 2016 Apr;30(4):627-35. doi: 10.1002/ptr.5571. Epub 2016 Jan 27.

PMID:
26816234
25.

Modification Effects of Changes in Job Demands on Associations Between Changes in Testosterone Levels and Andropause Symptoms: 2-Year Follow-up Study in Male Middle-Aged Japanese Workers.

Hirokawa K, Taniguchi T, Fujii Y, Takaki J, Tsutsumi A.

Int J Behav Med. 2016 Aug;23(4):464-72. doi: 10.1007/s12529-015-9530-y.

PMID:
26714462
26.

Moderating effects of salivary testosterone levels on associations between job demand and psychological stress response in Japanese medical workers.

Hirokawa K, Miwa M, Taniguchi T, Tsuchiya M, Kawakami N.

Ind Health. 2016 Jun 10;54(3):194-203. doi: 10.2486/indhealth.2015-0113. Epub 2015 Dec 1.

27.

Improvement in Human Immune Function with Changes in Intestinal Microbiota by Salacia reticulata Extract Ingestion: A Randomized Placebo-Controlled Trial.

Oda Y, Ueda F, Utsuyama M, Kamei A, Kakinuma C, Abe K, Hirokawa K.

PLoS One. 2015 Dec 2;10(12):e0142909. doi: 10.1371/journal.pone.0142909. eCollection 2015.

28.

An Autopsy Case of Dementia with Lewy Bodies with Vocal Cord Abductor Paralysis.

Toru S, Uchihara T, Hara M, Mae S, Toru M, Hirokawa K, Endo T, Sugawara E, Kitagawa M, Kobayashi T.

Eur Neurol. 2015;74(3-4):186-7. doi: 10.1159/000441448. Epub 2015 Nov 10. No abstract available.

29.

Associations of workplace bullying and harassment with stress reactions: a two-year follow-up study.

Taniguchi T, Takaki J, Hirokawa K, Fujii Y, Harano K.

Ind Health. 2016;54(2):131-8. doi: 10.2486/indhealth.2014-0206. Epub 2015 Nov 3.

30.

Synthesis and inhibitory activity of substrate-analog fructosyl peptide oxidase inhibitors.

Watanabe B, Ichiyanagi A, Hirokawa K, Gomi K, Nakatsu T, Kato H, Kajiyama N.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):3910-3. doi: 10.1016/j.bmcl.2015.07.045. Epub 2015 Jul 23.

PMID:
26235953
31.

Trade off situation between thymus and growth hormone: age-related decline of growth hormone is a cause of thymic involution but favorable for elongation of lifespan.

Hirokawa K, Utsuyama M, Kikuchi Y.

Biogerontology. 2016 Feb;17(1):55-9. doi: 10.1007/s10522-015-9590-z. Epub 2015 Jul 14.

PMID:
26169108
32.

Novel glucose dehydrogenase from Mucor prainii: Purification, characterization, molecular cloning and gene expression in Aspergillus sojae.

Satake R, Ichiyanagi A, Ichikawa K, Hirokawa K, Araki Y, Yoshimura T, Gomi K.

J Biosci Bioeng. 2015 Nov;120(5):498-503. doi: 10.1016/j.jbiosc.2015.03.012. Epub 2015 Apr 23.

PMID:
25912449
33.

Menopausal status in relation to cardiovascular stress reactivity in healthy Japanese participants.

Hirokawa K, Nagayoshi M, Ohira T, Kajiura M, Kitamura A, Kiyama M, Okada T, Iso H.

Psychosom Med. 2014 Nov-Dec;76(9):701-8. doi: 10.1097/PSY.0000000000000121.

PMID:
25333497
34.

Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation.

Harris JA, Hirokawa KE, Sorensen SA, Gu H, Mills M, Ng LL, Bohn P, Mortrud M, Ouellette B, Kidney J, Smith KA, Dang C, Sunkin S, Bernard A, Oh SW, Madisen L, Zeng H.

Front Neural Circuits. 2014 Jul 10;8:76. doi: 10.3389/fncir.2014.00076. eCollection 2014.

35.

Aging is something like an opera which can be constructed by many players: an interview with Katsuiku Hirokawa.

Hirokawa K, Fulop T.

Biogerontology. 2014;15(5):535-42. doi: 10.1007/s10522-014-9518-z. Epub 2014 Jul 27. No abstract available.

PMID:
25064313
36.

Diagnosis and management of Enterococcus spp infections during rehabilitation of cold-stunned Kemp's ridley turtles (Lepidochelys kempii): 50 cases (2006-2012).

Innis CJ, Braverman H, Cavin JM, Ceresia ML, Baden LR, Kuhn DM, Frasca S Jr, McGowan JP, Hirokawa K, Weber ES 3rd, Stacy B, Merigo C.

J Am Vet Med Assoc. 2014 Aug 1;245(3):315-23. doi: 10.2460/javma.245.3.315.

PMID:
25029311
37.

Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice.

Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES.

Cereb Cortex. 2015 Sep;25(9):2707-18. doi: 10.1093/cercor/bhu067. Epub 2014 Apr 29.

38.

A mesoscale connectome of the mouse brain.

Oh SW, Harris JA, Ng L, Winslow B, Cain N, Mihalas S, Wang Q, Lau C, Kuan L, Henry AM, Mortrud MT, Ouellette B, Nguyen TN, Sorensen SA, Slaughterbeck CR, Wakeman W, Li Y, Feng D, Ho A, Nicholas E, Hirokawa KE, Bohn P, Joines KM, Peng H, Hawrylycz MJ, Phillips JW, Hohmann JG, Wohnoutka P, Gerfen CR, Koch C, Bernard A, Dang C, Jones AR, Zeng H.

Nature. 2014 Apr 10;508(7495):207-14. doi: 10.1038/nature13186. Epub 2014 Apr 2.

39.

Systematic comparison of adeno-associated virus and biotinylated dextran amine reveals equivalent sensitivity between tracers and novel projection targets in the mouse brain.

Wang Q, Henry AM, Harris JA, Oh SW, Joines KM, Nyhus J, Hirokawa KE, Dee N, Mortrud M, Parry S, Ouellette B, Caldejon S, Bernard A, Jones AR, Zeng H, Hohmann JG.

J Comp Neurol. 2014 Jun 15;522(9):1989-2012. doi: 10.1002/cne.23567.

PMID:
24639291
40.

Job stress and agentic-communal personality traits related to serum cortisol levels of male workers in a Japanese medium-sized company: a cross-sectional study.

Hirokawa K, Taniguchi T, Fujii Y.

Int J Behav Med. 2015 Feb;22(1):11-7. doi: 10.1007/s12529-014-9403-9.

PMID:
24590829
41.

Strategy of Daiichi Sankyo discovery research in oncology.

Akahane K, Hirokawa K.

Jpn J Clin Oncol. 2014 Feb;44(2):109-15. doi: 10.1093/jjco/hyt200. Epub 2014 Jan 23. Review.

PMID:
24459194
42.

Associations of workplace bullying and harassment with pain.

Takaki J, Taniguchi T, Hirokawa K.

Int J Environ Res Public Health. 2013 Sep 25;10(10):4560-70. doi: 10.3390/ijerph10104560.

43.

Correlated gene expression and target specificity demonstrate excitatory projection neuron diversity.

Sorensen SA, Bernard A, Menon V, Royall JJ, Glattfelder KJ, Desta T, Hirokawa K, Mortrud M, Miller JA, Zeng H, Hohmann JG, Jones AR, Lein ES.

Cereb Cortex. 2015 Feb;25(2):433-49. doi: 10.1093/cercor/bht243. Epub 2013 Sep 7.

PMID:
24014670
44.

Mortality risks in relation to occupational category and position among the Japanese working population: the Jichi Medical School (JMS) cohort study.

Hirokawa K, Tsutsumi A, Kayaba K; Jichi Medical Cohort study group.

BMJ Open. 2013 Aug 1;3(8). pii: e002690. doi: 10.1136/bmjopen-2013-002690.

45.

Eye-blink behaviors in 71 species of primates.

Tada H, Omori Y, Hirokawa K, Ohira H, Tomonaga M.

PLoS One. 2013 May 31;8(5):e66018. doi: 10.1371/journal.pone.0066018. Print 2013.

46.

Slower immune system aging in women versus men in the Japanese population.

Hirokawa K, Utsuyama M, Hayashi Y, Kitagawa M, Makinodan T, Fulop T.

Immun Ageing. 2013 May 15;10(1):19. doi: 10.1186/1742-4933-10-19.

47.

Isoform transition from four-repeat to three-repeat tau underlies dendrosomatic and regional progression of neurofibrillary pathology.

Hara M, Hirokawa K, Kamei S, Uchihara T.

Acta Neuropathol. 2013 Apr;125(4):565-79. doi: 10.1007/s00401-013-1097-6. Epub 2013 Feb 14.

PMID:
23407988
48.

Crystallization and preliminary crystallographic analysis of two eukaryotic fructosyl peptide oxidases.

Ichiyanagi A, Hirokawa K, Gomi K, Nakatsu T, Kato H, Kajiyama N.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Feb 1;69(Pt 2):130-3. doi: 10.1107/S1744309112051445. Epub 2013 Jan 30.

49.

Immunosenescence and cancer.

Fulop T, Larbi A, Witkowski JM, Kotb R, Hirokawa K, Pawelec G.

Crit Rev Oncog. 2013;18(6):489-513. Review.

PMID:
24579731
50.

Effects of a stress management program for hospital staffs on their coping strategies and interpersonal behaviors.

Hirokawa K, Taniguchi T, Tsuchiya M, Kawakami N.

Ind Health. 2012;50(6):487-98. Epub 2012 Oct 8.

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